IRIS
CAMPIANI, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 23.868
EU - Europa 19.134
AS - Asia 10.230
SA - Sud America 1.589
AF - Africa 532
OC - Oceania 49
Continente sconosciuto - Info sul continente non disponibili 17
AN - Antartide 1
Totale 55.420
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Nazione #
US - Stati Uniti d'America 23.555
GB - Regno Unito 4.342
RU - Federazione Russa 3.883
CN - Cina 3.613
SG - Singapore 3.030
IT - Italia 2.562
IE - Irlanda 2.318
BR - Brasile 1.284
UA - Ucraina 1.249
SE - Svezia 1.226
DE - Germania 1.219
FR - Francia 1.015
VN - Vietnam 994
HK - Hong Kong 830
FI - Finlandia 510
KR - Corea 483
IN - India 355
ZA - Sudafrica 256
TR - Turchia 206
CA - Canada 172
ES - Italia 156
BD - Bangladesh 127
NL - Olanda 124
AR - Argentina 110
PL - Polonia 91
MX - Messico 89
AT - Austria 75
JP - Giappone 74
IQ - Iraq 71
NG - Nigeria 69
CZ - Repubblica Ceca 60
BE - Belgio 54
CI - Costa d'Avorio 52
PK - Pakistan 48
VE - Venezuela 46
ID - Indonesia 41
IR - Iran 38
RO - Romania 36
UZ - Uzbekistan 36
AU - Australia 35
EC - Ecuador 34
SA - Arabia Saudita 33
CL - Cile 31
GR - Grecia 31
KE - Kenya 31
MA - Marocco 31
CO - Colombia 30
LT - Lituania 27
EG - Egitto 24
IL - Israele 24
JO - Giordania 23
AZ - Azerbaigian 22
TN - Tunisia 21
AE - Emirati Arabi Uniti 18
KZ - Kazakistan 18
PT - Portogallo 18
CH - Svizzera 17
ET - Etiopia 17
PE - Perù 16
DK - Danimarca 14
EE - Estonia 14
PH - Filippine 14
GE - Georgia 13
UY - Uruguay 13
BO - Bolivia 12
EU - Europa 12
JM - Giamaica 12
NP - Nepal 12
DZ - Algeria 11
LV - Lettonia 11
MY - Malesia 11
NZ - Nuova Zelanda 11
PA - Panama 11
BY - Bielorussia 10
HU - Ungheria 10
PY - Paraguay 10
KG - Kirghizistan 9
RS - Serbia 9
BG - Bulgaria 8
CR - Costa Rica 8
LA - Repubblica Popolare Democratica del Laos 8
PS - Palestinian Territory 8
LB - Libano 7
MD - Moldavia 7
OM - Oman 7
SY - Repubblica araba siriana 7
TH - Thailandia 7
TW - Taiwan 7
AL - Albania 6
SK - Slovacchia (Repubblica Slovacca) 6
SN - Senegal 6
AM - Armenia 5
HN - Honduras 5
MC - Monaco 5
NO - Norvegia 5
QA - Qatar 5
AO - Angola 4
BB - Barbados 4
DO - Repubblica Dominicana 4
HR - Croazia 4
Totale 55.352
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Città #
Southend 3.822
Dallas 3.101
Fairfield 2.762
Dublin 2.297
Ashburn 1.957
Singapore 1.666
Chandler 1.250
Woodbridge 1.197
Jacksonville 1.009
Moscow 996
Seattle 992
Wilmington 980
Houston 929
Cambridge 928
Santa Clara 926
Beijing 866
Siena 799
Hong Kong 784
San Jose 757
Ann Arbor 654
Hefei 637
Seoul 475
Princeton 396
Los Angeles 360
Nanjing 350
Ho Chi Minh City 312
The Dalles 310
New York 276
Lauterbourg 259
Hanoi 249
Johannesburg 233
Council Bluffs 215
Helsinki 203
Milan 193
Boardman 185
Florence 166
Dearborn 164
Fremont 156
Munich 155
Shanghai 148
San Diego 139
Izmir 136
São Paulo 129
Nanchang 127
Bengaluru 122
Buffalo 116
Rome 113
Orem 107
San Mateo 90
Washington 84
London 83
Lappeenranta 82
Düsseldorf 80
Menlo Park 77
Málaga 77
Frankfurt am Main 76
Warsaw 72
Shenyang 71
Hebei 68
Tokyo 67
Chennai 62
Jiaxing 59
Kunming 58
Da Nang 57
Abuja 56
Redondo Beach 56
Lancaster 55
Venezia 55
Guangzhou 54
Abidjan 52
Montreal 52
Redwood City 51
Tianjin 51
Changsha 50
Vienna 49
Denver 48
Brussels 46
Haiphong 46
Brno 43
Jinan 42
Ningbo 42
San Francisco 42
Brooklyn 41
Amsterdam 39
Norwalk 39
Nuremberg 39
Chicago 38
Columbus 38
Toronto 38
Atlanta 37
Phoenix 37
Aachen 34
Rio de Janeiro 34
Stockholm 34
Dhaka 33
Turku 33
Belo Horizonte 32
Tashkent 32
Mexico City 31
Portsmouth 31
Totale 37.796
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Nome #
The insulin-releasing agent quercetin-3-oleate stimulates CaV1.2 channels similarly to quercetin, though with a reduced vasorelaxant activity 453
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation 435
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 402
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 394
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 392
Development of novel cyclic peptides as pro-apoptotic agents 384
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 374
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 364
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 356
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 335
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 330
A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin 329
Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation 324
Synthetic spirocyclic endoperoxides: new antimalarial scaffolds 324
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 320
Unveiling Wound Healing Properties of Biostimulated Walnut Kernel Extracts via Epithelial Mesenchymal Transition: Switching a Nutritional Matrix into a Therapeutic Remedy 317
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis 316
Natural Compounds and Synthetic Drugs to Target FAAH Enzyme 312
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 311
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 311
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 310
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 310
Identification of novel fluorescent probes preventing PrP(Sc) replication in prion diseases 307
A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides 304
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 304
1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators 299
A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues 298
A stereoselective approach to peptidomimetic BACE1 inhibitors 290
The 1-(2,3-dichlorophenyl)-piperazine-to-aripiprazole ratio at steady state in rats and schizophrenic patients 286
Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies 286
A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors 279
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 277
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine d3 and serotonin 5-HT 1A and 5-HT2A receptors: Design, synthesis, and effects on behavior 276
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase 275
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 274
A palladium-catalyzed synthetic approach to new Huperzine A analogues modified at the pyridone ring 273
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 273
Novel quinolone-based potent and selective HDAC6 inhibitors: synthesis, molecular modeling studies and biological investigation 273
Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors 272
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents 271
Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling 270
Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents 270
An efficient approach to chiral C8/C9-Piperazino-Substituted 1,4-Benzodiazepin-2-ones as peptidomimetic scaffolds 267
Old but gold: tracking the new guise of Histone Deacetylase 6 (HDAC6) enzyme as a biomarker and therapeutic target in rare diseases 267
Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR):  From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry Blockers 264
A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor 263
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 263
Discovery of Potent Inhibitors of Human and Mouse Fatty Acid Amide Hydrolases 263
Telomerase-based cancer therapeutics: a review on their clinical trials 261
Non-Nucleoside Inhibitors of Human Adenosine Kinase: Synthesis, Molecular Modeling, and Biological Studies 260
Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boride reduction: a convenient approach to 4-aminoquinolines and derivatives 260
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) 259
Development of Antitubercular Compounds Based on a 4-Quinolylhydrazone Scaffold. Further Structure-activity Relationship Studies 257
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 255
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents 255
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy 255
Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors 250
Synthetic studies toward 1,2-dioxanes as precursors of potential endoperoxide-containing antimalarials 248
Synthesis of Dihydroplakortin, 6-epi-Dihydroplakortin, and Their C10-Desethyl Analogues 245
Pyrrolo 1,3 benzothiazepine-based Atypical Antipsychotic Agents. Synthesis, Structure-Activity Relationship, Molecular Modeling, and Biological Studies 244
Discovery of Bishomo(hetero)arylpiperazines as Novel Multifunctional Ligands Targeting Dopamine D-3 and Serotonin 5-HT1A and 5-HT2A Receptors 244
Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663 242
A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs 242
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 242
Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore 242
ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE 241
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 239
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation 239
Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold 239
Novel aryl piperazine derivatives with medical utility 237
Discovery of Huperzine A/Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Mid-gorge Recognition Sites 237
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 237
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders 237
Synthesis and structure–activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 237
Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological Studies 236
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling 236
Pyrrolobenzoxazepinone Derivatives as Non-Nucleoside HIV-1 RT Inhibitors: Further Structure-Activity Relationship Studies and Identification of More Potent Broad-Spectrum HIV-1 RT Inhibitors with Antiviral Activity 235
Malaria chemotherapy: recent advances in drug development 235
'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one 235
(+)-(R)- and (−)-(S)-Perhexiline maleate: enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages 235
Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization 234
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors 234
New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine Structure 233
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy 230
Synthesis and Antiplasmodial Activity of Bicyclic Dioxanes as Simplified Dihydroplakortin Analogues 230
Disease modifying anti-Alzheimer’s drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregation 230
Screening and phenotypical characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) inhibitors as multistage antischistosomal agents 230
An approach to modified heterocyclic analogues of huperzine A and isohuperzine A. Synthesis of the pyrimidone and pyrazole analogues, and their anticholinesterase activity 229
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells 229
The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity 229
Computational tool for fast in silico evaluation of hERG K+ channel affinity 227
A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents 226
Retinitis pigmentosa and retinal degenerations: deciphering pathways and targets for drug discovery and development 226
The Interactions of the 5-HT3 Receptor with Quipazine-Like Arylpiperazine Ligands. The Journey Track at the End of the First Decade of the Third Millennium 225
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations 224
ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS. 223
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 222
New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding site 221
Raising the bar in anticancer therapy: recent advances in, and perspectives on, telomerase inhibitors 219
Pyrrolo[1,5]benzoxa(thia)zepines as a New Class of Potent Apoptotic Agents. Biological Studies and Identification of an Intracellular Location of Their Drug Target 218
Totale 27.302
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Categoria #
all - tutte 163.193
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 163.193
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.258 0 0 0 0 0 0 0 0 0 557 440 261
2021/20223.544 302 526 243 194 174 82 200 140 170 437 390 686
2022/20234.785 284 398 635 661 534 960 117 387 427 135 157 90
2023/20243.997 157 81 351 177 214 1.084 1.234 69 34 119 139 338
2024/20257.496 197 342 859 392 864 396 213 389 815 339 701 1.989
2025/202617.380 1.377 2.501 2.663 2.206 3.399 829 2.136 621 648 1.000 0 0
Totale 56.125