IRIS
CAMPIANI, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 25.859
EU - Europa 20.533
AS - Asia 10.494
SA - Sud America 1.612
Continente sconosciuto - Info sul continente non disponibili 737
AF - Africa 534
OC - Oceania 51
AN - Antartide 1
Totale 59.821
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Nazione #
US - Stati Uniti d'America 25.468
GB - Regno Unito 4.350
IT - Italia 3.922
RU - Federazione Russa 3.883
CN - Cina 3.660
SG - Singapore 3.108
IE - Irlanda 2.318
BR - Brasile 1.298
UA - Ucraina 1.250
SE - Svezia 1.229
DE - Germania 1.221
FR - Francia 1.018
VN - Vietnam 994
HK - Hong Kong 853
FI - Finlandia 510
KR - Corea 483
IN - India 359
ZA - Sudafrica 257
BD - Bangladesh 223
CA - Canada 214
TR - Turchia 207
ES - Italia 163
NL - Olanda 132
AR - Argentina 112
MX - Messico 98
PL - Polonia 92
AT - Austria 75
JP - Giappone 75
IQ - Iraq 71
NG - Nigeria 69
CZ - Repubblica Ceca 60
BE - Belgio 56
CI - Costa d'Avorio 52
PK - Pakistan 51
VE - Venezuela 46
ID - Indonesia 43
IR - Iran 41
RO - Romania 37
UZ - Uzbekistan 36
AU - Australia 35
CO - Colombia 35
EC - Ecuador 35
SA - Arabia Saudita 33
CL - Cile 32
GR - Grecia 32
KE - Kenya 31
MA - Marocco 31
LT - Lituania 27
EG - Egitto 24
IL - Israele 24
JM - Giamaica 23
JO - Giordania 23
AZ - Azerbaigian 22
TN - Tunisia 21
AE - Emirati Arabi Uniti 18
KZ - Kazakistan 18
PT - Portogallo 18
CH - Svizzera 17
ET - Etiopia 17
PE - Perù 16
MY - Malesia 15
PH - Filippine 15
DK - Danimarca 14
EE - Estonia 14
GE - Georgia 13
NZ - Nuova Zelanda 13
UY - Uruguay 13
BO - Bolivia 12
EU - Europa 12
NP - Nepal 12
DZ - Algeria 11
LV - Lettonia 11
PA - Panama 11
BY - Bielorussia 10
HU - Ungheria 10
PY - Paraguay 10
KG - Kirghizistan 9
RS - Serbia 9
BG - Bulgaria 8
CR - Costa Rica 8
HN - Honduras 8
LA - Repubblica Popolare Democratica del Laos 8
MD - Moldavia 8
PS - Palestinian Territory 8
TH - Thailandia 8
LB - Libano 7
OM - Oman 7
SY - Repubblica araba siriana 7
TW - Taiwan 7
AL - Albania 6
SK - Slovacchia (Repubblica Slovacca) 6
SN - Senegal 6
AM - Armenia 5
BB - Barbados 5
MC - Monaco 5
NI - Nicaragua 5
NO - Norvegia 5
QA - Qatar 5
AO - Angola 4
DO - Repubblica Dominicana 4
Totale 59.020
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Città #
Southend 3.822
Dallas 3.127
Fairfield 2.762
Dublin 2.297
Ashburn 2.207
Singapore 1.692
Chandler 1.250
Woodbridge 1.197
Santa Clara 1.030
Jacksonville 1.010
San Jose 1.009
Moscow 996
Seattle 996
Wilmington 980
Houston 936
Cambridge 928
Milan 886
Beijing 877
Hong Kong 802
Siena 800
Ann Arbor 654
Hefei 638
Council Bluffs 559
Seoul 475
Los Angeles 401
Princeton 397
Nanjing 350
Rome 339
The Dalles 325
New York 318
Ho Chi Minh City 312
Lauterbourg 259
Hanoi 249
Johannesburg 234
Helsinki 203
Florence 192
Boardman 185
Dearborn 164
Fremont 157
Munich 155
Shanghai 152
San Diego 145
Izmir 136
São Paulo 129
Buffalo 127
Nanchang 127
Bengaluru 122
Orem 113
Washington 91
San Mateo 90
London 89
Columbus 86
Lappeenranta 82
Düsseldorf 80
Frankfurt am Main 77
Menlo Park 77
Málaga 77
Warsaw 72
Shenyang 71
Hebei 68
Tokyo 67
Figino 66
Chicago 64
Turin 64
Chennai 62
Jiaxing 59
Kunming 58
Da Nang 57
Abuja 56
Montreal 56
Redondo Beach 56
Guangzhou 55
Lancaster 55
Venezia 55
Naples 54
Denver 53
Abidjan 52
Redwood City 51
Tianjin 51
Changsha 50
San Francisco 50
Atlanta 49
Phoenix 49
Vienna 49
Brussels 46
Haiphong 46
Toronto 46
Brno 43
Brooklyn 43
Jinan 42
Ningbo 42
Bologna 40
Mexico City 40
Norwalk 40
Amsterdam 39
Nuremberg 39
Aachen 34
Boston 34
Dhaka 34
Rio de Janeiro 34
Totale 40.161
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Nome #
The insulin-releasing agent quercetin-3-oleate stimulates CaV1.2 channels similarly to quercetin, though with a reduced vasorelaxant activity 478
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation 451
Pyrrolo 1,3 benzothiazepine-based Atypical Antipsychotic Agents. Synthesis, Structure-Activity Relationship, Molecular Modeling, and Biological Studies 417
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 411
Natural Compounds and Synthetic Drugs to Target FAAH Enzyme 400
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 399
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 397
Development of novel cyclic peptides as pro-apoptotic agents 392
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 391
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 375
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 369
A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin 361
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 348
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 347
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis 342
Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation 337
Synthetic spirocyclic endoperoxides: new antimalarial scaffolds 336
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 335
Unveiling Wound Healing Properties of Biostimulated Walnut Kernel Extracts via Epithelial Mesenchymal Transition: Switching a Nutritional Matrix into a Therapeutic Remedy 333
A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors 325
A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides 324
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 322
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 322
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 321
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 320
Identification of novel fluorescent probes preventing PrP(Sc) replication in prion diseases 315
A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues 311
1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators 310
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 309
A stereoselective approach to peptidomimetic BACE1 inhibitors 300
Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies 299
The 1-(2,3-dichlorophenyl)-piperazine-to-aripiprazole ratio at steady state in rats and schizophrenic patients 294
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase 289
A palladium-catalyzed synthetic approach to new Huperzine A analogues modified at the pyridone ring 288
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 288
An efficient approach to chiral C8/C9-Piperazino-Substituted 1,4-Benzodiazepin-2-ones as peptidomimetic scaffolds 286
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine d3 and serotonin 5-HT 1A and 5-HT2A receptors: Design, synthesis, and effects on behavior 285
Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents 284
Novel quinolone-based potent and selective HDAC6 inhibitors: synthesis, molecular modeling studies and biological investigation 283
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents 282
A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor 282
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 282
Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling 280
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 276
Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors 275
Discovery of Potent Inhibitors of Human and Mouse Fatty Acid Amide Hydrolases 275
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) 273
Telomerase-based cancer therapeutics: a review on their clinical trials 272
Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR):  From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry Blockers 271
Development of Antitubercular Compounds Based on a 4-Quinolylhydrazone Scaffold. Further Structure-activity Relationship Studies 270
Old but gold: tracking the new guise of Histone Deacetylase 6 (HDAC6) enzyme as a biomarker and therapeutic target in rare diseases 270
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 269
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy 269
Non-Nucleoside Inhibitors of Human Adenosine Kinase: Synthesis, Molecular Modeling, and Biological Studies 266
Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boride reduction: a convenient approach to 4-aminoquinolines and derivatives 266
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 266
Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors 265
Synthesis of Dihydroplakortin, 6-epi-Dihydroplakortin, and Their C10-Desethyl Analogues 265
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents 263
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy 260
Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663 258
Synthetic studies toward 1,2-dioxanes as precursors of potential endoperoxide-containing antimalarials 257
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 256
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation 255
Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold 254
A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs 252
ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE 252
(+)-(R)- and (−)-(S)-Perhexiline maleate: enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages 252
Synthesis and structure–activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 252
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling 251
Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore 250
Discovery of Bishomo(hetero)arylpiperazines as Novel Multifunctional Ligands Targeting Dopamine D-3 and Serotonin 5-HT1A and 5-HT2A Receptors 248
Pyrrolobenzoxazepinone Derivatives as Non-Nucleoside HIV-1 RT Inhibitors: Further Structure-Activity Relationship Studies and Identification of More Potent Broad-Spectrum HIV-1 RT Inhibitors with Antiviral Activity 247
Malaria chemotherapy: recent advances in drug development 247
Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization 246
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 245
Synthesis and Antiplasmodial Activity of Bicyclic Dioxanes as Simplified Dihydroplakortin Analogues 244
Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological Studies 244
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 244
Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor 243
Discovery of Huperzine A/Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Mid-gorge Recognition Sites 243
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells 243
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors 243
New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine Structure 242
An approach to modified heterocyclic analogues of huperzine A and isohuperzine A. Synthesis of the pyrimidone and pyrazole analogues, and their anticholinesterase activity 242
'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one 241
Disease modifying anti-Alzheimer’s drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregation 241
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders 241
Novel aryl piperazine derivatives with medical utility 240
The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity 239
Computational tool for fast in silico evaluation of hERG K+ channel affinity 239
New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding site 238
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations 237
Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products 237
The Interactions of the 5-HT3 Receptor with Quipazine-Like Arylpiperazine Ligands. The Journey Track at the End of the First Decade of the Third Millennium 236
Synthetic studies toward bicyclic endoperoxides presenting polar side chains 236
Screening and phenotypical characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) inhibitors as multistage antischistosomal agents 235
Extra virgin olive oil extracts of indigenous Southern Tuscany cultivar act as anti-inflammatory and vasorelaxant nutraceuticals 235
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 233
Retinitis pigmentosa and retinal degenerations: deciphering pathways and targets for drug discovery and development 233
Totale 28.762
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Categoria #
all - tutte 178.685
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 178.685
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.242 0 526 243 194 174 82 200 140 170 437 390 686
2022/20234.785 284 398 635 661 534 960 117 387 427 135 157 90
2023/20243.997 157 81 351 177 214 1.084 1.234 69 34 119 139 338
2024/20257.496 197 342 859 392 864 396 213 389 815 339 701 1.989
2025/202619.624 1.377 2.501 2.663 2.206 3.399 829 2.136 621 648 1.110 465 1.669
2026/20271.452 786 666 0 0 0 0 0 0 0 0 0 0
Totale 59.821