IRIS
CAMPIANI, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 27.916
EU - Europa 20.865
AS - Asia 10.602
SA - Sud America 1.714
Continente sconosciuto - Info sul continente non disponibili 751
AF - Africa 551
OC - Oceania 54
AN - Antartide 1
Totale 62.454
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Nazione #
US - Stati Uniti d'America 27.349
GB - Regno Unito 4.417
IT - Italia 4.061
RU - Federazione Russa 3.905
CN - Cina 3.666
SG - Singapore 3.117
IE - Irlanda 2.323
BR - Brasile 1.335
SE - Svezia 1.265
UA - Ucraina 1.256
DE - Germania 1.239
FR - Francia 1.022
VN - Vietnam 1.000
HK - Hong Kong 854
FI - Finlandia 510
KR - Corea 484
IN - India 363
CA - Canada 283
ZA - Sudafrica 259
BD - Bangladesh 226
TR - Turchia 210
ES - Italia 165
NL - Olanda 135
AR - Argentina 118
MX - Messico 102
PL - Polonia 93
JP - Giappone 79
AT - Austria 75
IQ - Iraq 71
NG - Nigeria 69
CO - Colombia 68
CZ - Repubblica Ceca 60
BE - Belgio 58
ID - Indonesia 58
VE - Venezuela 57
PK - Pakistan 54
CI - Costa d'Avorio 52
IL - Israele 50
EC - Ecuador 47
IR - Iran 41
AU - Australia 37
RO - Romania 37
SA - Arabia Saudita 37
UZ - Uzbekistan 36
CL - Cile 35
LT - Lituania 35
CR - Costa Rica 32
GR - Grecia 32
KE - Kenya 32
MA - Marocco 31
JM - Giamaica 28
EE - Estonia 26
EG - Egitto 24
JO - Giordania 23
AZ - Azerbaigian 22
MY - Malesia 22
AE - Emirati Arabi Uniti 21
PH - Filippine 21
TN - Tunisia 21
CH - Svizzera 19
HN - Honduras 19
KZ - Kazakistan 18
PT - Portogallo 18
DK - Danimarca 17
ET - Etiopia 17
GT - Guatemala 16
PE - Perù 16
NI - Nicaragua 15
GE - Georgia 14
NP - Nepal 14
NZ - Nuova Zelanda 14
PR - Porto Rico 13
SC - Seychelles 13
UY - Uruguay 13
BO - Bolivia 12
EU - Europa 12
DZ - Algeria 11
KG - Kirghizistan 11
LV - Lettonia 11
PA - Panama 11
SV - El Salvador 11
BY - Bielorussia 10
HU - Ungheria 10
PY - Paraguay 10
TT - Trinidad e Tobago 10
BG - Bulgaria 9
CW - ???statistics.table.value.countryCode.CW??? 9
RS - Serbia 9
TH - Thailandia 9
LA - Repubblica Popolare Democratica del Laos 8
MD - Moldavia 8
PS - Palestinian Territory 8
AL - Albania 7
LB - Libano 7
OM - Oman 7
SY - Repubblica araba siriana 7
TW - Taiwan 7
BB - Barbados 6
SK - Slovacchia (Repubblica Slovacca) 6
SN - Senegal 6
Totale 61.616
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Città #
Southend 3.822
Dallas 3.139
Fairfield 2.762
Ashburn 2.564
Dublin 2.300
Singapore 1.696
San Jose 1.322
Chandler 1.250
Woodbridge 1.198
Santa Clara 1.072
Jacksonville 1.017
Seattle 998
Moscow 996
Wilmington 981
Houston 939
Cambridge 928
Milan 903
Beijing 878
Hong Kong 803
Siena 800
Ann Arbor 654
Hefei 638
Council Bluffs 560
Seoul 476
Los Angeles 436
Princeton 399
Rome 351
Nanjing 350
New York 342
The Dalles 330
Ho Chi Minh City 314
Lauterbourg 259
Hanoi 251
Johannesburg 235
Helsinki 203
Boardman 198
Florence 198
Dearborn 165
Fremont 157
Munich 156
Shanghai 152
San Diego 146
Buffalo 138
Izmir 136
São Paulo 134
Nanchang 127
Bengaluru 122
Orem 114
Washington 97
London 91
San Mateo 90
Columbus 87
Düsseldorf 83
Lappeenranta 82
Frankfurt am Main 80
Chicago 79
Menlo Park 77
Málaga 77
Turin 73
Warsaw 72
North Bergen 71
Shenyang 71
Tokyo 69
Figino 68
Hebei 68
Phoenix 67
Denver 66
Atlanta 64
Montreal 63
Brooklyn 62
Chennai 62
Naples 61
Jiaxing 59
Kunming 58
San Francisco 58
Da Nang 57
Abuja 56
Lancaster 56
Redondo Beach 56
Guangzhou 55
Toronto 55
Venezia 55
Abidjan 52
Redwood City 51
Tianjin 51
Changsha 50
Vienna 50
Brussels 46
Haiphong 46
Brno 43
Bologna 42
Jinan 42
Ningbo 42
Norwalk 42
Amsterdam 41
Mexico City 40
Nuremberg 39
Philadelphia 39
Stockholm 39
Boston 36
Totale 41.245
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Nome #
The insulin-releasing agent quercetin-3-oleate stimulates CaV1.2 channels similarly to quercetin, though with a reduced vasorelaxant activity 497
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation 467
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 428
Pyrrolo 1,3 benzothiazepine-based Atypical Antipsychotic Agents. Synthesis, Structure-Activity Relationship, Molecular Modeling, and Biological Studies 427
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 409
Natural Compounds and Synthetic Drugs to Target FAAH Enzyme 406
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 405
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 402
Development of novel cyclic peptides as pro-apoptotic agents 399
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 382
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 380
A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin 368
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 364
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis 357
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 356
Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation 347
Unveiling Wound Healing Properties of Biostimulated Walnut Kernel Extracts via Epithelial Mesenchymal Transition: Switching a Nutritional Matrix into a Therapeutic Remedy 342
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 342
Synthetic spirocyclic endoperoxides: new antimalarial scaffolds 342
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 339
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 337
A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors 335
A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides 332
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 330
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 327
Identification of novel fluorescent probes preventing PrP(Sc) replication in prion diseases 324
1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators 320
A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues 320
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 317
Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies 315
A stereoselective approach to peptidomimetic BACE1 inhibitors 311
The 1-(2,3-dichlorophenyl)-piperazine-to-aripiprazole ratio at steady state in rats and schizophrenic patients 309
Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling 304
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 299
An efficient approach to chiral C8/C9-Piperazino-Substituted 1,4-Benzodiazepin-2-ones as peptidomimetic scaffolds 298
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase 298
A palladium-catalyzed synthetic approach to new Huperzine A analogues modified at the pyridone ring 297
Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents 296
A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor 293
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine d3 and serotonin 5-HT 1A and 5-HT2A receptors: Design, synthesis, and effects on behavior 293
Novel quinolone-based potent and selective HDAC6 inhibitors: synthesis, molecular modeling studies and biological investigation 293
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents 292
Discovery of Potent Inhibitors of Human and Mouse Fatty Acid Amide Hydrolases 291
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 289
Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors 286
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents 286
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) 283
Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR):  From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry Blockers 280
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 279
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy 279
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy 278
Development of Antitubercular Compounds Based on a 4-Quinolylhydrazone Scaffold. Further Structure-activity Relationship Studies 276
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 276
Telomerase-based cancer therapeutics: a review on their clinical trials 276
Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors 275
Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boride reduction: a convenient approach to 4-aminoquinolines and derivatives 274
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 274
Old but gold: tracking the new guise of Histone Deacetylase 6 (HDAC6) enzyme as a biomarker and therapeutic target in rare diseases 274
Non-Nucleoside Inhibitors of Human Adenosine Kinase: Synthesis, Molecular Modeling, and Biological Studies 271
Synthesis of Dihydroplakortin, 6-epi-Dihydroplakortin, and Their C10-Desethyl Analogues 270
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation 267
(+)-(R)- and (−)-(S)-Perhexiline maleate: enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages 266
Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663 265
ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE 265
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 264
Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold 264
Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products 264
Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor 263
Synthetic studies toward 1,2-dioxanes as precursors of potential endoperoxide-containing antimalarials 262
Synthesis and structure–activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 260
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling 259
A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs 258
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 258
Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization 257
Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore 256
New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine Structure 255
Discovery of Bishomo(hetero)arylpiperazines as Novel Multifunctional Ligands Targeting Dopamine D-3 and Serotonin 5-HT1A and 5-HT2A Receptors 255
Malaria chemotherapy: recent advances in drug development 253
An approach to modified heterocyclic analogues of huperzine A and isohuperzine A. Synthesis of the pyrimidone and pyrazole analogues, and their anticholinesterase activity 253
Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological Studies 252
Pyrrolobenzoxazepinone Derivatives as Non-Nucleoside HIV-1 RT Inhibitors: Further Structure-Activity Relationship Studies and Identification of More Potent Broad-Spectrum HIV-1 RT Inhibitors with Antiviral Activity 251
Synthesis and Antiplasmodial Activity of Bicyclic Dioxanes as Simplified Dihydroplakortin Analogues 251
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 251
Disease modifying anti-Alzheimer’s drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregation 250
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors 250
'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one 249
The Interactions of the 5-HT3 Receptor with Quipazine-Like Arylpiperazine Ligands. The Journey Track at the End of the First Decade of the Third Millennium 249
The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity 249
Extra virgin olive oil extracts of indigenous Southern Tuscany cultivar act as anti-inflammatory and vasorelaxant nutraceuticals 249
Discovery of Huperzine A/Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Mid-gorge Recognition Sites 247
New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding site 247
Computational tool for fast in silico evaluation of hERG K+ channel affinity 247
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations 247
A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents 246
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells 246
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders 246
Novel aryl piperazine derivatives with medical utility 243
A palladium-catalyzed route to huperzine A and its analogs and their anticholinesterase activity 243
Screening and phenotypical characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) inhibitors as multistage antischistosomal agents 242
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 241
Totale 29.756
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Categoria #
all - tutte 188.852
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 188.852
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.279 0 0 0 0 174 82 200 140 170 437 390 686
2022/20234.785 284 398 635 661 534 960 117 387 427 135 157 90
2023/20243.997 157 81 351 177 214 1.084 1.234 69 34 119 139 338
2024/20257.496 197 342 859 392 864 396 213 389 815 339 701 1.989
2025/202619.624 1.377 2.501 2.663 2.206 3.399 829 2.136 621 648 1.110 465 1.669
2026/20274.085 786 746 1.364 1.091 98 0 0 0 0 0 0 0
Totale 62.454