IRIS
CAMPIANI, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 24.521
EU - Europa 19.271
AS - Asia 10.419
SA - Sud America 1.592
AF - Africa 533
OC - Oceania 51
Continente sconosciuto - Info sul continente non disponibili 17
AN - Antartide 1
Totale 56.405
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Nazione #
US - Stati Uniti d'America 24.172
GB - Regno Unito 4.346
RU - Federazione Russa 3.883
CN - Cina 3.643
SG - Singapore 3.077
IT - Italia 2.688
IE - Irlanda 2.318
BR - Brasile 1.286
UA - Ucraina 1.249
SE - Svezia 1.226
DE - Germania 1.220
FR - Francia 1.015
VN - Vietnam 994
HK - Hong Kong 840
FI - Finlandia 510
KR - Corea 483
IN - India 359
ZA - Sudafrica 257
BD - Bangladesh 216
TR - Turchia 207
CA - Canada 191
ES - Italia 156
NL - Olanda 130
AR - Argentina 110
MX - Messico 97
PL - Polonia 91
AT - Austria 75
JP - Giappone 75
IQ - Iraq 71
NG - Nigeria 69
CZ - Repubblica Ceca 60
BE - Belgio 54
CI - Costa d'Avorio 52
PK - Pakistan 50
VE - Venezuela 46
ID - Indonesia 42
IR - Iran 38
RO - Romania 36
UZ - Uzbekistan 36
AU - Australia 35
EC - Ecuador 35
SA - Arabia Saudita 33
CL - Cile 31
GR - Grecia 31
KE - Kenya 31
MA - Marocco 31
CO - Colombia 30
LT - Lituania 27
EG - Egitto 24
IL - Israele 24
JO - Giordania 23
AZ - Azerbaigian 22
TN - Tunisia 21
AE - Emirati Arabi Uniti 18
JM - Giamaica 18
KZ - Kazakistan 18
PT - Portogallo 18
CH - Svizzera 17
ET - Etiopia 17
PE - Perù 16
MY - Malesia 15
DK - Danimarca 14
EE - Estonia 14
PH - Filippine 14
GE - Georgia 13
NZ - Nuova Zelanda 13
UY - Uruguay 13
BO - Bolivia 12
EU - Europa 12
NP - Nepal 12
DZ - Algeria 11
LV - Lettonia 11
PA - Panama 11
BY - Bielorussia 10
HU - Ungheria 10
PY - Paraguay 10
KG - Kirghizistan 9
RS - Serbia 9
BG - Bulgaria 8
CR - Costa Rica 8
LA - Repubblica Popolare Democratica del Laos 8
PS - Palestinian Territory 8
LB - Libano 7
MD - Moldavia 7
OM - Oman 7
SY - Repubblica araba siriana 7
TH - Thailandia 7
TW - Taiwan 7
AL - Albania 6
SK - Slovacchia (Repubblica Slovacca) 6
SN - Senegal 6
AM - Armenia 5
HN - Honduras 5
MC - Monaco 5
NO - Norvegia 5
QA - Qatar 5
AO - Angola 4
BB - Barbados 4
DO - Repubblica Dominicana 4
HR - Croazia 4
Totale 56.334
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Città #
Southend 3.822
Dallas 3.115
Fairfield 2.762
Dublin 2.297
Ashburn 2.005
Singapore 1.674
Chandler 1.250
Woodbridge 1.197
Jacksonville 1.009
Moscow 996
Seattle 993
Wilmington 980
Santa Clara 967
Houston 934
San Jose 934
Cambridge 928
Beijing 869
Siena 799
Hong Kong 793
Ann Arbor 654
Hefei 638
Seoul 475
Princeton 396
Los Angeles 380
Nanjing 350
The Dalles 325
Ho Chi Minh City 312
New York 302
Lauterbourg 259
Hanoi 249
Johannesburg 234
Council Bluffs 221
Milan 212
Helsinki 203
Boardman 185
Florence 178
Dearborn 164
Fremont 157
Munich 155
Shanghai 150
San Diego 143
Izmir 136
São Paulo 129
Nanchang 127
Buffalo 124
Bengaluru 122
Rome 118
Orem 111
San Mateo 90
London 85
Washington 85
Lappeenranta 82
Düsseldorf 80
Frankfurt am Main 77
Menlo Park 77
Málaga 77
Warsaw 72
Shenyang 71
Hebei 68
Tokyo 67
Chennai 62
Jiaxing 59
Kunming 58
Da Nang 57
Abuja 56
Redondo Beach 56
Guangzhou 55
Lancaster 55
Venezia 55
Montreal 54
Abidjan 52
Denver 52
Redwood City 51
Tianjin 51
Changsha 50
Vienna 49
San Francisco 48
Brussels 46
Haiphong 46
Toronto 45
Atlanta 44
Chicago 44
Brno 43
Phoenix 43
Jinan 42
Ningbo 42
Brooklyn 41
Norwalk 40
Amsterdam 39
Mexico City 39
Nuremberg 39
Columbus 38
Naples 35
Aachen 34
Rio de Janeiro 34
Stockholm 34
Dhaka 33
Turku 33
Belo Horizonte 32
Tashkent 32
Totale 38.282
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Nome #
The insulin-releasing agent quercetin-3-oleate stimulates CaV1.2 channels similarly to quercetin, though with a reduced vasorelaxant activity 463
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation 438
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 403
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 397
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 395
Development of novel cyclic peptides as pro-apoptotic agents 388
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 379
Natural Compounds and Synthetic Drugs to Target FAAH Enzyme 372
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 367
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 358
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 340
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 335
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis 334
A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin 331
Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation 328
Synthetic spirocyclic endoperoxides: new antimalarial scaffolds 328
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 323
Unveiling Wound Healing Properties of Biostimulated Walnut Kernel Extracts via Epithelial Mesenchymal Transition: Switching a Nutritional Matrix into a Therapeutic Remedy 318
A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors 315
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 314
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 312
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 311
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 311
Identification of novel fluorescent probes preventing PrP(Sc) replication in prion diseases 308
1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators 305
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 305
A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides 304
A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues 300
A stereoselective approach to peptidomimetic BACE1 inhibitors 292
Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies 289
The 1-(2,3-dichlorophenyl)-piperazine-to-aripiprazole ratio at steady state in rats and schizophrenic patients 286
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase 280
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine d3 and serotonin 5-HT 1A and 5-HT2A receptors: Design, synthesis, and effects on behavior 278
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 278
Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling 276
Novel quinolone-based potent and selective HDAC6 inhibitors: synthesis, molecular modeling studies and biological investigation 276
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 276
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 275
Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents 274
A palladium-catalyzed synthetic approach to new Huperzine A analogues modified at the pyridone ring 273
Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors 273
An efficient approach to chiral C8/C9-Piperazino-Substituted 1,4-Benzodiazepin-2-ones as peptidomimetic scaffolds 272
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents 272
Old but gold: tracking the new guise of Histone Deacetylase 6 (HDAC6) enzyme as a biomarker and therapeutic target in rare diseases 267
A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor 266
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 265
Discovery of Potent Inhibitors of Human and Mouse Fatty Acid Amide Hydrolases 265
Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR):  From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry Blockers 264
Non-Nucleoside Inhibitors of Human Adenosine Kinase: Synthesis, Molecular Modeling, and Biological Studies 263
Telomerase-based cancer therapeutics: a review on their clinical trials 262
Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boride reduction: a convenient approach to 4-aminoquinolines and derivatives 261
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) 261
Development of Antitubercular Compounds Based on a 4-Quinolylhydrazone Scaffold. Further Structure-activity Relationship Studies 260
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy 260
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 257
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents 256
Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors 252
Synthesis of Dihydroplakortin, 6-epi-Dihydroplakortin, and Their C10-Desethyl Analogues 252
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy 251
Synthetic studies toward 1,2-dioxanes as precursors of potential endoperoxide-containing antimalarials 251
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 250
Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663 246
Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore 246
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation 246
Pyrrolo 1,3 benzothiazepine-based Atypical Antipsychotic Agents. Synthesis, Structure-Activity Relationship, Molecular Modeling, and Biological Studies 245
A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs 245
Discovery of Bishomo(hetero)arylpiperazines as Novel Multifunctional Ligands Targeting Dopamine D-3 and Serotonin 5-HT1A and 5-HT2A Receptors 245
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 243
Discovery of Huperzine A/Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Mid-gorge Recognition Sites 242
ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE 242
Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold 242
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 240
Novel aryl piperazine derivatives with medical utility 239
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders 239
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling 239
Malaria chemotherapy: recent advances in drug development 238
Synthesis and structure–activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 238
Pyrrolobenzoxazepinone Derivatives as Non-Nucleoside HIV-1 RT Inhibitors: Further Structure-Activity Relationship Studies and Identification of More Potent Broad-Spectrum HIV-1 RT Inhibitors with Antiviral Activity 237
Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological Studies 237
'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one 237
(+)-(R)- and (−)-(S)-Perhexiline maleate: enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages 237
Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization 236
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors 236
The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity 235
New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine Structure 234
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells 233
Disease modifying anti-Alzheimer’s drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregation 232
Synthesis and Antiplasmodial Activity of Bicyclic Dioxanes as Simplified Dihydroplakortin Analogues 231
Screening and phenotypical characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) inhibitors as multistage antischistosomal agents 231
ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS. 230
An approach to modified heterocyclic analogues of huperzine A and isohuperzine A. Synthesis of the pyrimidone and pyrazole analogues, and their anticholinesterase activity 230
Computational tool for fast in silico evaluation of hERG K+ channel affinity 228
A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents 227
Retinitis pigmentosa and retinal degenerations: deciphering pathways and targets for drug discovery and development 227
The Interactions of the 5-HT3 Receptor with Quipazine-Like Arylpiperazine Ligands. The Journey Track at the End of the First Decade of the Third Millennium 226
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 224
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations 224
Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products 224
New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding site 223
Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor 222
Totale 27.691
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Categoria #
all - tutte 170.165
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 170.165
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021261 0 0 0 0 0 0 0 0 0 0 0 261
2021/20223.544 302 526 243 194 174 82 200 140 170 437 390 686
2022/20234.785 284 398 635 661 534 960 117 387 427 135 157 90
2023/20243.997 157 81 351 177 214 1.084 1.234 69 34 119 139 338
2024/20257.496 197 342 859 392 864 396 213 389 815 339 701 1.989
2025/202618.375 1.377 2.501 2.663 2.206 3.399 829 2.136 621 648 1.110 465 420
Totale 57.120