CAMPIANI, GIUSEPPE
CAMPIANI, GIUSEPPE
Dipartimento di Biotecnologie, Chimica e Farmacia
'BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines
2008-01-01 L., Greene; Campiani, Giuseppe; M., Lawler; D., Williams; D. M., Zisterer
'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one
2002-01-01 Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; E., Morelli; P., Minetti; O., Tinti; Nacci, Vito
(+)-(R)- and (−)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages
2020-01-01 Guidi, A.; Prasanth Saraswati, A.; Relitti, N.; Gimmelli, R.; Saccoccia, F.; Sirignano, C.; Taglialatela-Scafati, O.; Campiani, G.; Ruberti, G.; Gemma, S.
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation
2018-01-01 Brogi, Simone; Brindisi, Margherita; Butini, Stefania; Kshirsagar, Giridhar U.; Maramai, Samuele; Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonytė, Raminta; Han, Liwei; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S.
1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators
2008-01-01 Butini, Stefania; DARRYL S., Pickering; Elena, Morelli; SANNA COCCONE, Salvatore; Trotta, Francesco; MERI DE, Angelis; Guarino, Egeria; Fiorini, Isabella; Campiani, Giuseppe; Ettore, Novellino; Arne, Schousboe; JEPPE K., Christensen; Gemma, Sandra
A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor
1994-01-01 Giovanni, Greco; Ettore, Novellino; Fiorini, Isabella; Nacci, Vito; Campiani, Giuseppe; Silvia M., Ciani; Antonio, Garofalo; Paola, Bernasconi; Tiziana, Mennini
A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors
1995-01-01 Alessandro, Dalpiaz; Valerio, Bertolasi; Pier Andrea, Borea; Nacci, Vito; Fiorini, Isabella; Campiani, Giuseppe; Tiziana, Mennini; Cristina, Manzoni; Ettore, Novellino; Giovanni, Greco
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents
2018-01-01 Federico, Stefano; Khan, Tuhina; Relitti, Nicola; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Novellino, Ettore; Zisterer, Daniela M.; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision
2019-01-01 Chemi, G.; Brindisi, M.; Brogi, S.; Relitti, N.; Butini, S.; Gemma, S.; Campiani, G.
A NEW MICROTUBULE TARGETING COMPOUND PBOX-15 INHIBITS T- CELL MIGRATION VIA POST-TRANSLATIONAL MODIFICATIONS OF TUBULIN;
2008-01-01 NAVIN K., Verma; Eugene, Dempsey; Jennifer, Conroy; Peter, Olwell; ANTHONY M., Mcelligott; ANTHONY M., Davies; Dermot, Kelleher; Butini, Stefania; Campiani, Giuseppe; D., CLIVE WILLIAMS; DANIELA M., Zisterer; Mark, Lawler; Yuri, Volkov
A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds
2021-01-01 Ghanim, Magda; Relitti, Nicola; Mcmanus, Gavin; Butini, Stefania; Cappelli, Andrea; Campiani, Giuseppe; Mok, K H; Kelly, Vincent P
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis
2021-01-01 Vanni, Francesca; Lopresti, Ludovica; Zurli, Vanessa; Kabanova, Anna; Cattaneo, Francesca; Sicuranza, Anna; Gozzetti, Alessandro; Gemma, Sandra; Zisterer, Daniela M; Bocchia, Monica; Campiani, Giuseppe; Baldari, Cosima T; Butini, Stefania; Ulivieri, Cristina
A palladium-catalyzed route to huperzine A and its analogs and their anticholinesterase activity
1993-01-01 Campiani, Giuseppe; Li Qiang, Sun; Alan P., Kozikowski; Patricia, Aagaard; Michael, Mckinney
A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents.
2001-01-01 Campiani, Giuseppe; M., De Angelis; S., Armaroli; C., Fattorusso; B., Catalanotti; A., Ramunno; Nacci, Vito; E., Novellino; C., Grewer; D., Ionescu; T., Rauen; R., Griffiths; C., Sinclair; E., Fumagalli; T., Mennini
A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting Profiles
2019-01-01 Battah, B.; Chemi, G.; Butini, S.; Campiani, G.; Brogi, S.; Delogu, G.; Gemma, S.
A stereoselective approach to peptidomimetic BACE1 inhibitors
2013-01-01 Butini, Stefania; Emanuele, Gabellieri; Brindisi, Margherita; Giovani, Simone; Maramai, Samuele; Kshirsagar, Giridhar; Egeria, Guarino; Brogi, Simone; Valeria La, Pietra; Mariateresa, Giustiniano; Luciana, Marinelli; Ettore, Novellino; Campiani, Giuseppe; Cappelli, Andrea; Gemma, Sandra
A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues
2013-01-01 Brindisi, Margherita; Gemma, Sandra; Alfano, Gloria; Kshirsagar, Giridhar; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania
A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs
2012-01-01 Butini, Stefania; Gemma, Sandra; Campiani, Giuseppe
A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides
2013-01-01 Gemma, Sandra; Kunjir, SANIL ASHOK; Brindisi, Margherita; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania
Activation of the c-Jun NH2 Terminal Kinase (JNK) Signalling Pathway is Essential During PBOX-6-Induced Apoptosis in Chronic Myelogenous leukemia (CML) Cells
2002-01-01 MC GEE, M.; Campiani, G.; Ramunno, A.; Williams, C; Zisterer, D; Nacci, V.; Lawler, M.
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 'BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines | 1-gen-2008 | L., Greene; Campiani, Giuseppe; M., Lawler; D., Williams; D. M., Zisterer | - | |
| 'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one | 1-gen-2002 | Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; E., Morelli; P., Minetti; O., Tinti; Nacci, Vito | - | |
| (+)-(R)- and (−)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages | 1-gen-2020 | Guidi, A.; Prasanth Saraswati, A.; Relitti, N.; Gimmelli, R.; Saccoccia, F.; Sirignano, C.; Taglialatela-Scafati, O.; Campiani, G.; Ruberti, G.; Gemma, S. | - | |
| (S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation | 1-gen-2018 | Brogi, Simone; Brindisi, Margherita; Butini, Stefania; Kshirsagar, Giridhar U.; Maramai, Samuele; Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonytė, Raminta; Han, Liwei; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S. | - | |
| 1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators | 1-gen-2008 | Butini, Stefania; DARRYL S., Pickering; Elena, Morelli; SANNA COCCONE, Salvatore; Trotta, Francesco; MERI DE, Angelis; Guarino, Egeria; Fiorini, Isabella; Campiani, Giuseppe; Ettore, Novellino; Arne, Schousboe; JEPPE K., Christensen; Gemma, Sandra | - | |
| A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor | 1-gen-1994 | Giovanni, Greco; Ettore, Novellino; Fiorini, Isabella; Nacci, Vito; Campiani, Giuseppe; Silvia M., Ciani; Antonio, Garofalo; Paola, Bernasconi; Tiziana, Mennini | - | |
| A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors | 1-gen-1995 | Alessandro, Dalpiaz; Valerio, Bertolasi; Pier Andrea, Borea; Nacci, Vito; Fiorini, Isabella; Campiani, Giuseppe; Tiziana, Mennini; Cristina, Manzoni; Ettore, Novellino; Giovanni, Greco | - | |
| A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents | 1-gen-2018 | Federico, Stefano; Khan, Tuhina; Relitti, Nicola; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Novellino, Ettore; Zisterer, Daniela M.; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania | - | |
| A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision | 1-gen-2019 | Chemi, G.; Brindisi, M.; Brogi, S.; Relitti, N.; Butini, S.; Gemma, S.; Campiani, G. | - | |
| A NEW MICROTUBULE TARGETING COMPOUND PBOX-15 INHIBITS T- CELL MIGRATION VIA POST-TRANSLATIONAL MODIFICATIONS OF TUBULIN; | 1-gen-2008 | NAVIN K., Verma; Eugene, Dempsey; Jennifer, Conroy; Peter, Olwell; ANTHONY M., Mcelligott; ANTHONY M., Davies; Dermot, Kelleher; Butini, Stefania; Campiani, Giuseppe; D., CLIVE WILLIAMS; DANIELA M., Zisterer; Mark, Lawler; Yuri, Volkov | - | |
| A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds | 1-gen-2021 | Ghanim, Magda; Relitti, Nicola; Mcmanus, Gavin; Butini, Stefania; Cappelli, Andrea; Campiani, Giuseppe; Mok, K H; Kelly, Vincent P | - | |
| A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis | 1-gen-2021 | Vanni, Francesca; Lopresti, Ludovica; Zurli, Vanessa; Kabanova, Anna; Cattaneo, Francesca; Sicuranza, Anna; Gozzetti, Alessandro; Gemma, Sandra; Zisterer, Daniela M; Bocchia, Monica; Campiani, Giuseppe; Baldari, Cosima T; Butini, Stefania; Ulivieri, Cristina | - | |
| A palladium-catalyzed route to huperzine A and its analogs and their anticholinesterase activity | 1-gen-1993 | Campiani, Giuseppe; Li Qiang, Sun; Alan P., Kozikowski; Patricia, Aagaard; Michael, Mckinney | - | |
| A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents. | 1-gen-2001 | Campiani, Giuseppe; M., De Angelis; S., Armaroli; C., Fattorusso; B., Catalanotti; A., Ramunno; Nacci, Vito; E., Novellino; C., Grewer; D., Ionescu; T., Rauen; R., Griffiths; C., Sinclair; E., Fumagalli; T., Mennini | - | |
| A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting Profiles | 1-gen-2019 | Battah, B.; Chemi, G.; Butini, S.; Campiani, G.; Brogi, S.; Delogu, G.; Gemma, S. | - | |
| A stereoselective approach to peptidomimetic BACE1 inhibitors | 1-gen-2013 | Butini, Stefania; Emanuele, Gabellieri; Brindisi, Margherita; Giovani, Simone; Maramai, Samuele; Kshirsagar, Giridhar; Egeria, Guarino; Brogi, Simone; Valeria La, Pietra; Mariateresa, Giustiniano; Luciana, Marinelli; Ettore, Novellino; Campiani, Giuseppe; Cappelli, Andrea; Gemma, Sandra | - | |
| A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues | 1-gen-2013 | Brindisi, Margherita; Gemma, Sandra; Alfano, Gloria; Kshirsagar, Giridhar; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania | - | |
| A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs | 1-gen-2012 | Butini, Stefania; Gemma, Sandra; Campiani, Giuseppe | - | |
| A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides | 1-gen-2013 | Gemma, Sandra; Kunjir, SANIL ASHOK; Brindisi, Margherita; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania | - | |
| Activation of the c-Jun NH2 Terminal Kinase (JNK) Signalling Pathway is Essential During PBOX-6-Induced Apoptosis in Chronic Myelogenous leukemia (CML) Cells | 1-gen-2002 | MC GEE, M.; Campiani, G.; Ramunno, A.; Williams, C; Zisterer, D; Nacci, V.; Lawler, M. | - |