CAMPIANI, GIUSEPPE
CAMPIANI, GIUSEPPE
Dipartimento di Biotecnologie, Chimica e Farmacia
'BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines
2008-01-01 L., Greene; Campiani, Giuseppe; M., Lawler; D., Williams; D. M., Zisterer
'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one
2002-01-01 Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Morelli, Elena; Minetti, Patrizia; Tinti, Ornella; Nacci, Vito
(+)-(R)- and (−)-(S)-Perhexiline maleate: enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages
2020-01-01 Guidi, A.; Prasanth Saraswati, A.; Relitti, N.; Gimmelli, R.; Saccoccia, F.; Sirignano, C.; Taglialatela-Scafati, O.; Campiani, G.; Ruberti, G.; Gemma, S.
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation
2018-01-01 Brogi, Simone; Brindisi, Margherita; Butini, Stefania; Kshirsagar, Giridhar U.; Maramai, Samuele; Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonytė, Raminta; Han, Liwei; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S.
1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators
2008-01-01 Butini, Stefania; Pickering, Darryl S.; Morelli, Elena; Coccone, Salvatore Sanna; Trotta, Francesco; De Angelis, Meri; Guarino, Egeria; Fiorini, Isabella; Campiani, Giuseppe; Novellino, Ettore; Schousboe, Arne; Christensen, Jeppe K.; Gemma, Sandra
A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor
1994-01-01 Greco, Giovanni; Novellino, Ettore; Fiorini, Isabella; Nacci, Vito; Campiani, Giuseppe; Ciani, Silvia M.; Garofalo, Antonio; Bernasconi, Paola; Mennini, Tiziana
A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors
1995-01-01 Dalpiaz, Alessandro; Bertolasi, Valerio; Boreal, Pier Andrea; Nacci, Vito; Fiorini, Isabella; Campiani, Giuseppe; Mennini, Tiziana; Manzoni, Cristina; Novellino, Ettore; Greco, Giovanni
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents
2018-01-01 Federico, Stefano; Khan, Tuhina; Relitti, Nicola; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Novellino, Ettore; Zisterer, Daniela M.; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision
2019-01-01 Chemi, G.; Brindisi, M.; Brogi, S.; Relitti, N.; Butini, S.; Gemma, S.; Campiani, G.
A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin
2008-01-01 Verma, Navin K.; Dempsey, Eugene; Conroy, Jennifer; Olwell, Peter; Mcelligott, Anthony M.; Davies, Anthony M.; Kelleher, Dermot; Butini, Stefania; Campiani, Giuseppe; Williams, D. Clive; Zisterer, Daniela M.; Lawler, Mark; Volkov, Yuri
A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds
2021-01-01 Ghanim, Magda; Relitti, Nicola; Mcmanus, Gavin; Butini, Stefania; Cappelli, Andrea; Campiani, Giuseppe; Mok, K H; Kelly, Vincent P
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis
2021-01-01 Vanni, Francesca; Lopresti, Ludovica; Zurli, Vanessa; Kabanova, Anna; Cattaneo, Francesca; Sicuranza, Anna; Gozzetti, Alessandro; Gemma, Sandra; Zisterer, Daniela M; Bocchia, Monica; Campiani, Giuseppe; Baldari, Cosima T; Butini, Stefania; Ulivieri, Cristina
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients
2024-01-01 Rossi, Sara; Tatangelo, Vanessa; Dichiara, Maria; Butini, Stefania; Gemma, Sandra; Brogi, Simone; Pasquini, Silvia; Cappello, Martina; Vincenzi, Fabrizio; Varani, Katia; Lopresti, Ludovica; Malchiodi, Margherita; Carrara, Chiara; Gozzetti, Alessandro; Bocchia, Monica; Marotta, Giuseppe; Patrussi, Laura; Carullo, Gabriele; Baldari, Cosima T.; Campiani, Giuseppe
A palladium-catalyzed route to huperzine A and its analogs and their anticholinesterase activity
1993-01-01 Campiani, Giuseppe; Sun, Li-Qiang; Kozikowski, Alan P.; Aagaard, Patricia; Mckinney, Michael
A palladium-catalyzed synthetic approach to new Huperzine A analogues modified at the pyridone ring
2003-01-01 Gemma, Sandra; Butini, Stefania; Fattorusso, Caterina; Fiorini, Isabella; Nacci, Vito; Bellebaum, Katherine; Mckissic, Down; Saxena, Ashima; Campiani, Giuseppe
A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents
2001-01-01 Campiani, G.; De Angelis, M.; Armaroli, S.; Fattorusso, C.; Catalanotti, B.; Ramunno, A.; Nacci, V.; Novellino, E.; Grewer, C.; Ionescu, D.; Rauen, T.; Griffiths, R.
A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting Profiles
2019-01-01 Battah, B.; Chemi, G.; Butini, S.; Campiani, G.; Brogi, S.; Delogu, G.; Gemma, S.
A stereoselective approach to peptidomimetic BACE1 inhibitors
2013-01-01 Butini, Stefania; Gabellieri, Emanuele; Brindisi, Margherita; Giovani, Simone; Maramai, Samuele; Kshirsagar, Giridhar; Guarino, Egeria; Brogi, Simone; La Pietra, Valeria; Giustiniano, Mariateresa; Marinelli, Luciana; Novellino, Ettore; Campiani, Giuseppe; Cappelli, Andrea; Gemma, Sandra
A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues
2013-01-01 Brindisi, Margherita; Gemma, Sandra; Alfano, Gloria; Kshirsagar, Giridhar; Novellino, Ettore; Campiani, Giuseppe; Butini, Stefania
A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs
2012-01-01 Butini, Stefania; Gemma, Sandra; Campiani, Giuseppe
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 'BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines | 1-gen-2008 | L., Greene; Campiani, Giuseppe; M., Lawler; D., Williams; D. M., Zisterer | - | |
| 'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one | 1-gen-2002 | Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Morelli, Elena; Minetti, Patrizia; Tinti, Ornella; Nacci, Vito | - | |
| (+)-(R)- and (−)-(S)-Perhexiline maleate: enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages | 1-gen-2020 | Guidi, A.; Prasanth Saraswati, A.; Relitti, N.; Gimmelli, R.; Saccoccia, F.; Sirignano, C.; Taglialatela-Scafati, O.; Campiani, G.; Ruberti, G.; Gemma, S. | - | |
| (S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation | 1-gen-2018 | Brogi, Simone; Brindisi, Margherita; Butini, Stefania; Kshirsagar, Giridhar U.; Maramai, Samuele; Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonytė, Raminta; Han, Liwei; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S. | - | |
| 1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators | 1-gen-2008 | Butini, Stefania; Pickering, Darryl S.; Morelli, Elena; Coccone, Salvatore Sanna; Trotta, Francesco; De Angelis, Meri; Guarino, Egeria; Fiorini, Isabella; Campiani, Giuseppe; Novellino, Ettore; Schousboe, Arne; Christensen, Jeppe K.; Gemma, Sandra | - | |
| A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor | 1-gen-1994 | Greco, Giovanni; Novellino, Ettore; Fiorini, Isabella; Nacci, Vito; Campiani, Giuseppe; Ciani, Silvia M.; Garofalo, Antonio; Bernasconi, Paola; Mennini, Tiziana | - | |
| A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors | 1-gen-1995 | Dalpiaz, Alessandro; Bertolasi, Valerio; Boreal, Pier Andrea; Nacci, Vito; Fiorini, Isabella; Campiani, Giuseppe; Mennini, Tiziana; Manzoni, Cristina; Novellino, Ettore; Greco, Giovanni | - | |
| A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents | 1-gen-2018 | Federico, Stefano; Khan, Tuhina; Relitti, Nicola; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Novellino, Ettore; Zisterer, Daniela M.; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania | - | |
| A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision | 1-gen-2019 | Chemi, G.; Brindisi, M.; Brogi, S.; Relitti, N.; Butini, S.; Gemma, S.; Campiani, G. | - | |
| A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin | 1-gen-2008 | Verma, Navin K.; Dempsey, Eugene; Conroy, Jennifer; Olwell, Peter; Mcelligott, Anthony M.; Davies, Anthony M.; Kelleher, Dermot; Butini, Stefania; Campiani, Giuseppe; Williams, D. Clive; Zisterer, Daniela M.; Lawler, Mark; Volkov, Yuri | - | |
| A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds | 1-gen-2021 | Ghanim, Magda; Relitti, Nicola; Mcmanus, Gavin; Butini, Stefania; Cappelli, Andrea; Campiani, Giuseppe; Mok, K H; Kelly, Vincent P | - | |
| A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis | 1-gen-2021 | Vanni, Francesca; Lopresti, Ludovica; Zurli, Vanessa; Kabanova, Anna; Cattaneo, Francesca; Sicuranza, Anna; Gozzetti, Alessandro; Gemma, Sandra; Zisterer, Daniela M; Bocchia, Monica; Campiani, Giuseppe; Baldari, Cosima T; Butini, Stefania; Ulivieri, Cristina | - | |
| A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients | 1-gen-2024 | Rossi, Sara; Tatangelo, Vanessa; Dichiara, Maria; Butini, Stefania; Gemma, Sandra; Brogi, Simone; Pasquini, Silvia; Cappello, Martina; Vincenzi, Fabrizio; Varani, Katia; Lopresti, Ludovica; Malchiodi, Margherita; Carrara, Chiara; Gozzetti, Alessandro; Bocchia, Monica; Marotta, Giuseppe; Patrussi, Laura; Carullo, Gabriele; Baldari, Cosima T.; Campiani, Giuseppe | - | |
| A palladium-catalyzed route to huperzine A and its analogs and their anticholinesterase activity | 1-gen-1993 | Campiani, Giuseppe; Sun, Li-Qiang; Kozikowski, Alan P.; Aagaard, Patricia; Mckinney, Michael | - | |
| A palladium-catalyzed synthetic approach to new Huperzine A analogues modified at the pyridone ring | 1-gen-2003 | Gemma, Sandra; Butini, Stefania; Fattorusso, Caterina; Fiorini, Isabella; Nacci, Vito; Bellebaum, Katherine; Mckissic, Down; Saxena, Ashima; Campiani, Giuseppe | - | |
| A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents | 1-gen-2001 | Campiani, G.; De Angelis, M.; Armaroli, S.; Fattorusso, C.; Catalanotti, B.; Ramunno, A.; Nacci, V.; Novellino, E.; Grewer, C.; Ionescu, D.; Rauen, T.; Griffiths, R. | - | |
| A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting Profiles | 1-gen-2019 | Battah, B.; Chemi, G.; Butini, S.; Campiani, G.; Brogi, S.; Delogu, G.; Gemma, S. | - | |
| A stereoselective approach to peptidomimetic BACE1 inhibitors | 1-gen-2013 | Butini, Stefania; Gabellieri, Emanuele; Brindisi, Margherita; Giovani, Simone; Maramai, Samuele; Kshirsagar, Giridhar; Guarino, Egeria; Brogi, Simone; La Pietra, Valeria; Giustiniano, Mariateresa; Marinelli, Luciana; Novellino, Ettore; Campiani, Giuseppe; Cappelli, Andrea; Gemma, Sandra | - | |
| A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues | 1-gen-2013 | Brindisi, Margherita; Gemma, Sandra; Alfano, Gloria; Kshirsagar, Giridhar; Novellino, Ettore; Campiani, Giuseppe; Butini, Stefania | - | |
| A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs | 1-gen-2012 | Butini, Stefania; Gemma, Sandra; Campiani, Giuseppe | - |