IRIS
SANTUCCI, ANNALISA
 Distribuzione geografica
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Continente #
NA - Nord America 29.978
EU - Europa 24.215
AS - Asia 13.526
SA - Sud America 2.118
AF - Africa 702
OC - Oceania 47
Continente sconosciuto - Info sul continente non disponibili 21
Totale 70.607
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Nazione #
US - Stati Uniti d'America 29.547
GB - Regno Unito 5.699
RU - Federazione Russa 4.585
CN - Cina 4.521
SG - Singapore 4.262
IT - Italia 3.181
IE - Irlanda 2.801
BR - Brasile 1.764
DE - Germania 1.626
SE - Svezia 1.606
UA - Ucraina 1.504
FR - Francia 1.402
VN - Vietnam 1.277
HK - Hong Kong 980
KR - Corea 711
FI - Finlandia 690
IN - India 439
ZA - Sudafrica 269
TR - Turchia 257
CA - Canada 233
ES - Italia 228
BD - Bangladesh 226
NL - Olanda 176
PL - Polonia 136
AR - Argentina 132
CI - Costa d'Avorio 124
JP - Giappone 120
MX - Messico 116
BE - Belgio 110
NG - Nigeria 110
IQ - Iraq 97
CZ - Repubblica Ceca 94
PK - Pakistan 88
AT - Austria 71
ID - Indonesia 68
EC - Ecuador 54
IR - Iran 48
KE - Kenya 48
SA - Arabia Saudita 45
PT - Portogallo 40
UZ - Uzbekistan 40
AU - Australia 37
VE - Venezuela 37
AE - Emirati Arabi Uniti 36
EG - Egitto 34
JO - Giordania 33
EE - Estonia 32
AZ - Azerbaigian 30
LT - Lituania 30
MA - Marocco 30
CH - Svizzera 29
PE - Perù 28
TN - Tunisia 28
IL - Israele 27
CL - Cile 26
KZ - Kazakistan 26
PH - Filippine 26
CO - Colombia 25
RO - Romania 25
MY - Malesia 24
PY - Paraguay 22
EU - Europa 20
BO - Bolivia 19
GR - Grecia 19
JM - Giamaica 17
NP - Nepal 17
HU - Ungheria 16
LB - Libano 16
CR - Costa Rica 14
OM - Oman 14
RS - Serbia 14
BG - Bulgaria 13
DK - Danimarca 13
DZ - Algeria 13
TW - Taiwan 13
KG - Kirghizistan 12
SK - Slovacchia (Repubblica Slovacca) 12
AM - Armenia 11
ET - Etiopia 11
NO - Norvegia 11
PA - Panama 10
AL - Albania 9
BY - Bielorussia 9
DO - Repubblica Dominicana 9
GE - Georgia 9
NZ - Nuova Zelanda 9
UY - Uruguay 9
HR - Croazia 8
SN - Senegal 8
LV - Lettonia 7
NI - Nicaragua 7
SY - Repubblica araba siriana 7
AO - Angola 6
CG - Congo 6
PS - Palestinian Territory 6
TH - Thailandia 6
HN - Honduras 5
LA - Repubblica Popolare Democratica del Laos 5
LK - Sri Lanka 5
TT - Trinidad e Tobago 5
Totale 70.530
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Città #
Southend 4.948
Dallas 3.851
Menlo Park 2.842
Dublin 2.767
Singapore 2.445
Fairfield 2.326
Ashburn 2.093
Chandler 1.787
Moscow 1.233
Jacksonville 1.232
Santa Clara 1.185
San Jose 1.069
Woodbridge 1.054
Siena 981
Beijing 974
Wilmington 948
Hong Kong 931
Houston 871
Hefei 814
Seattle 810
Cambridge 749
Ann Arbor 716
Seoul 680
Princeton 535
Los Angeles 462
Nanjing 438
The Dalles 420
Milan 410
Ho Chi Minh City 370
New York 369
Helsinki 352
Lauterbourg 301
Hanoi 284
Munich 272
Council Bluffs 256
Boardman 249
Florence 246
Johannesburg 238
San Mateo 197
Buffalo 177
Shanghai 173
São Paulo 162
Izmir 153
Nanchang 153
Orem 146
San Diego 144
Rome 136
Bengaluru 127
Abidjan 124
Shenyang 121
Dearborn 118
Lancaster 115
Frankfurt am Main 111
London 111
Málaga 109
Warsaw 108
Abuja 105
Dong Ket 105
Fremont 104
Brussels 103
Columbus 96
Tokyo 89
Tianjin 86
Hebei 82
Redondo Beach 73
Chicago 72
Da Nang 72
Changsha 71
Toronto 69
Turku 69
Chennai 68
Phoenix 68
Redwood City 68
Montreal 67
Stockholm 67
Amsterdam 66
Kunming 66
Brooklyn 65
Denver 61
Rio de Janeiro 60
Atlanta 59
Brno 59
San Francisco 59
Washington 58
Guangzhou 54
Haiphong 54
Jiaxing 51
Boston 50
Jinan 50
Mexico City 47
Nuremberg 47
Düsseldorf 46
Norwalk 46
Manchester 45
Vienna 45
Belo Horizonte 44
Zhengzhou 44
Mumbai 43
Poplar 42
University Park 42
Totale 47.830
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Nome #
Chondroptosis in alkaptonuric cartilage 490
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 488
A new integrated and interactive tool applicable to inborn errors of metabolism: Application to alkaptonuria 485
Assessment of glutathione/glutathione disulphide ratio and S-glutathionylated proteins in human blood, solid tissues, and cultured cells 460
Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient 406
4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases 405
N-acetylcysteine ethyl ester as GSH enhancer in human primary endothelial cells: A comparative study with other drugs 404
Homogentisic acid induces morphological and mechanical aberration of ochronotic cartilage in alkaptonuria 403
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors 399
TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration 395
Biochemical and proteomic characterization of alkaptonuric chondrocytes 385
Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma 377
Histological and Ultrastructural Characterization of Alkaptonuric Tissues 375
CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration 369
Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria. 368
Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria 366
Antipeptide monoclonal antibodies inhibit the binding of rabiesvirus glycoprotein and alpha-bungarotoxin to the nicotinic acetylcholine receptor 364
Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium 362
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: preliminary in vitro studies with analogues of immucillin-G 360
Establishment of Four New Human Primary Cell Cultures from Chemo-Naïve Italian Osteosarcoma Patients 357
Effects of Nitisinone on Oxidative and Inflammatory Markers in Alkaptonuria: Results from SONIA1 and SONIA2 Studies 356
Beer promotes differentiation and mineralization of human osteoblastic cells: Role of silicon 354
A monoclonal antibody to a synthetic fragment of rabies virus glycoprotein binds ligands of the nicotinic cholinergic receptor 353
Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste 351
Alkaptonuria is a novel human secondary amyloidogenic disease 349
Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project 342
Angiogenesis in alkaptonuria 341
A structural bioinformatics investigation on protein–DNA complexes delineates their modes of interaction 330
Western blotting of total lysate of Helicobacter pylori in cases of atrophic body gastritis 323
A novel ex vivo organotypic culture model of alkaptonuria-ochronosis 316
A model of the rabies virus glycoprotein active site 315
H pylori infection and systemic antibodies to CagA and heat shock protein 60 in patients with coronary heart disease 303
Diagnosis of secondary amyloidosis in alkaptonuria 303
A combined ML and DFT strategy for the prediction of dye candidates for indoor DSSCs 302
Homogentisate 1,2 dioxygenase is expressed in human osteoarticular cells: implications in alkaptonuria. 301
Long-term effects of neridronate on human osteoblastic cell cultures 301
Different factors affecting human ANP amyloid aggregation and their implications in congestive heart failure 301
A proteomic study of human osteoblastic cells proliferation and differentiation 301
Biochemical investigation of the effects of human platelet releasates on human articular chondrocytes 301
Cytoskeleton Aberrations in Alkaptonuric Chondrocytes 300
Antimicrobial activity against Helicobacter pylori strains and antioxidant properties of blackberry leaves (Rubus ulmifolius) and isolated compounds 298
A sialoglycoprotein, gp20, of the human capacitated sperm surface is a homologue of the leukocyte CD52: analysis of the effect of anti-CD52 monoclonal antibody (CAMPATH-1) on capacitated spermatozoa 298
The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration 298
Quick Diagnosis of Alkaptonuria by Homogentisic Acid Determination in Urine Paper Spots 294
Application of proteomics to the study of Helicobacter pylori and implications for the clinic 292
Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1,2-dioxygenase mutants at the base of rare disease Alkaptonuria 292
Yield Determination of Bioethanol Production of Saccharomyces Cerevisiae Metabolic Process by Mathematical Modelling and In-Vivo 13C-NMR 291
Comparative proteomics in alkaptonuria provides insights into inflammation and oxidative stress 288
Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria 288
High performance liquid chromatography immunoaffinity purification of antibodies and antibody fragments 287
Amyloidosis in alkaptonuria 286
Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins 284
Proteomic investigation of dermal fibroblasts isolated from affected and unaffected skin samples from patients with limited cutaneous systemic sclerosis: 2 distinct entities? 284
An Introduction to Personalized Nutrition 284
A new light on Alkaptonuria: A Fourier-transform infrared microscopy (FTIRM) and low energy X-ray fluorescence (LEXRF) microscopy correlative study on a rare disease 283
Proteomic and redox-proteomic evaluation of homogentisic acid and ascorbic acid effects on human articular chondrocytes 279
Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria 279
Proteomic response to physiological fermentation stresses in a wild-type wine strain of Saccharomyces cerevisiae 275
Wild-type wine Saccharomyces cerevisiae as a tool to evaluate the effects on eukaryotic life of locally used herbicides 273
Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease 273
Interactive alkaptonuria database: investigating clinical data to improve patient care in a rare disease 272
Atrial natriuretic peptide aggregation and its control by plasma factors 270
Secondary amyloidosis in an alkaptonuric aortic valve 269
Modern proteomic methodologies for the characterization of lactosylation protein targets in milk 268
Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria 267
Omicron variants of SARS CoV-2 indicate a new antiviral strategy: Interfere with spike glycoprotein trimerization 265
Differentially activated Src kinase in chemo-naive human primary osteosarcoma cells and effects of a Src kinase inhibitor 265
Evaluation of anti-oxidant treatments in an in vitro model of alkaptonuric ochronosis 265
HIV-1 gp 120 binding to nicotinig receptors 264
Redox-proteomics of the effects of homogentisic acid in an in vitro human serum model of alkaptonuric ochronosis 264
Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’ in Italy 263
Comparative analysis of the effects of locally used herbicides and their active ingredients on a wild-type wine Saccharomyces cerevisiae strain 262
Antibacterial activity of grape extracts towards cagA positive and cagA negative Helicobacter pylori clinical isolates 262
Machine learning application for patient stratification and phenotype/genotype investigation in a rare disease 261
Affinity purification of rabies virus glycoprotein using immobilized antipeptide antibodies 260
Oxidative stress and mechanisms of ochronosis in alkaptonuria 260
Antimicrobial Activity of Plant Extracts against Helicobacter pylori 259
Bactericidal activity of grape, soy flour, tomato, and bramble leaf extracts to Helicobacter pylori 259
New 4-substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 259
Conformations and biological activities of Amyloid Beta Peptide 25-35 258
Homogentisate 1,2 dioxygenase is expressed in brain: implications in alkaptonuria 257
Purification of acidic synthetic peptides by high performance liquid chromatography using ammonium acetate buffer 253
Saccharomyces cerevisiae as a Tool to Evaluate the Effects of Herbicides on Eukaryotic Life 252
Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial 252
Helicobacter pylori infection and autoimmune thyroid diseases: The role of virulent strains 249
Pro-Apoptotic activity of French Polynesian Padina pavonica Extract on Human Osteosarcoma Cells 249
Metabolite and protein patterns in plasma of Lesch-nyhan syndrome patients 248
Cd93 signaling via rho proteins drives cytoskeletal remodeling in spreading endothelial cells 247
Helicobacter pylori: immunoproteomics related to different pathologies 244
Structure of rubella E1 glycoprotein epitopes established by multiple peptide synthesis 244
Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU 244
A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria 244
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells. 243
Cloning, characterization, and modeling of a monoclonal anti-human transferrin antibody that competes with the transferrin receptor 243
AKUImg: A database of cartilage images of Alkaptonuria patients 243
An antigenic determinant common to human chorionic somatomammotropin and human growth hormone revealed by limited proteolysis of immune complexes 242
Negative Helicobacter pylori status is associated with poor prognosis in patients with gastric cancer 242
Padina pavonica Extract Promotes In Vitro Differentiation and Functionality of Human Primary Osteoblasts 242
Animal and cell models for Lesch-Nyhan syndrome 241
Mapping phosphoproteins in Neisseria meningitidis serogroup A 240
Totale 30.378
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Categoria #
all - tutte 203.754
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 203.754
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021411 0 0 0 0 0 0 0 0 0 0 0 411
2021/20224.619 364 545 340 389 214 178 213 194 272 500 459 951
2022/20236.176 388 583 757 841 649 1.192 144 520 604 165 210 123
2023/20244.643 170 104 476 228 208 1.232 1.473 137 14 59 156 386
2024/20259.698 220 511 946 558 1.161 509 395 615 1.008 395 981 2.399
2025/202623.361 1.797 3.340 3.156 2.902 4.693 936 2.585 686 804 1.285 605 572
Totale 71.367