IRIS
SANTUCCI, ANNALISA
 Distribuzione geografica
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Continente #
NA - Nord America 29.069
EU - Europa 24.035
AS - Asia 13.334
SA - Sud America 2.115
AF - Africa 698
OC - Oceania 47
Continente sconosciuto - Info sul continente non disponibili 21
Totale 69.319
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Nazione #
US - Stati Uniti d'America 28.682
GB - Regno Unito 5.691
RU - Federazione Russa 4.584
CN - Cina 4.474
SG - Singapore 4.212
IT - Italia 3.023
IE - Irlanda 2.801
BR - Brasile 1.763
DE - Germania 1.626
SE - Svezia 1.606
UA - Ucraina 1.504
FR - Francia 1.402
VN - Vietnam 1.277
HK - Hong Kong 973
KR - Corea 708
FI - Finlandia 690
IN - India 439
ZA - Sudafrica 269
TR - Turchia 257
ES - Italia 226
CA - Canada 208
NL - Olanda 172
BD - Bangladesh 150
PL - Polonia 134
AR - Argentina 131
CI - Costa d'Avorio 124
JP - Giappone 119
MX - Messico 111
NG - Nigeria 110
BE - Belgio 107
IQ - Iraq 96
CZ - Repubblica Ceca 94
PK - Pakistan 88
AT - Austria 71
ID - Indonesia 67
EC - Ecuador 54
IR - Iran 48
KE - Kenya 48
SA - Arabia Saudita 45
PT - Portogallo 40
UZ - Uzbekistan 40
AU - Australia 37
VE - Venezuela 37
AE - Emirati Arabi Uniti 34
EE - Estonia 32
EG - Egitto 32
JO - Giordania 32
AZ - Azerbaigian 30
LT - Lituania 30
MA - Marocco 30
CH - Svizzera 29
PE - Perù 28
TN - Tunisia 28
IL - Israele 27
CL - Cile 26
KZ - Kazakistan 26
PH - Filippine 26
CO - Colombia 24
RO - Romania 24
MY - Malesia 22
PY - Paraguay 22
EU - Europa 20
BO - Bolivia 19
GR - Grecia 19
NP - Nepal 17
HU - Ungheria 16
LB - Libano 16
OM - Oman 14
RS - Serbia 14
BG - Bulgaria 13
DK - Danimarca 13
TW - Taiwan 13
DZ - Algeria 12
JM - Giamaica 12
KG - Kirghizistan 12
SK - Slovacchia (Repubblica Slovacca) 12
AM - Armenia 11
CR - Costa Rica 11
ET - Etiopia 11
NO - Norvegia 10
PA - Panama 10
AL - Albania 9
BY - Bielorussia 9
DO - Repubblica Dominicana 9
GE - Georgia 9
NZ - Nuova Zelanda 9
UY - Uruguay 9
HR - Croazia 8
SN - Senegal 8
LV - Lettonia 7
SY - Repubblica araba siriana 7
AO - Angola 6
CG - Congo 6
NI - Nicaragua 6
PS - Palestinian Territory 6
TH - Thailandia 6
HN - Honduras 5
LA - Repubblica Popolare Democratica del Laos 5
LK - Sri Lanka 5
BH - Bahrain 4
Totale 69.248
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Città #
Southend 4.948
Dallas 3.840
Menlo Park 2.842
Dublin 2.767
Singapore 2.439
Fairfield 2.326
Ashburn 2.034
Chandler 1.786
Moscow 1.233
Jacksonville 1.232
Santa Clara 1.148
Woodbridge 1.054
Siena 979
Beijing 970
Wilmington 947
Hong Kong 925
Houston 868
San Jose 868
Hefei 814
Seattle 808
Cambridge 749
Ann Arbor 716
Seoul 680
Princeton 535
Los Angeles 444
Nanjing 438
The Dalles 418
Ho Chi Minh City 370
Milan 370
Helsinki 352
New York 346
Lauterbourg 301
Hanoi 284
Munich 272
Council Bluffs 250
Boardman 249
Johannesburg 238
Florence 234
San Mateo 197
Shanghai 172
Buffalo 170
São Paulo 162
Izmir 153
Nanchang 153
Orem 144
San Diego 144
Bengaluru 127
Abidjan 124
Shenyang 121
Dearborn 117
Rome 116
Lancaster 115
Frankfurt am Main 111
London 110
Málaga 109
Warsaw 107
Abuja 105
Dong Ket 105
Fremont 103
Brussels 100
Columbus 94
Tokyo 89
Tianjin 86
Hebei 82
Redondo Beach 73
Da Nang 72
Changsha 70
Turku 69
Chennai 68
Redwood City 68
Stockholm 67
Amsterdam 66
Chicago 66
Kunming 66
Brooklyn 64
Montreal 63
Toronto 63
Denver 60
Rio de Janeiro 60
Brno 59
Phoenix 58
Washington 57
San Francisco 55
Guangzhou 54
Haiphong 54
Atlanta 52
Jiaxing 51
Jinan 50
Boston 49
Nuremberg 47
Düsseldorf 46
Norwalk 46
Manchester 45
Vienna 45
Belo Horizonte 44
Zhengzhou 44
Mumbai 43
Mexico City 42
Poplar 42
University Park 42
Totale 47.310
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Nome #
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 487
Chondroptosis in alkaptonuric cartilage 486
A new integrated and interactive tool applicable to inborn errors of metabolism: Application to alkaptonuria 482
Assessment of glutathione/glutathione disulphide ratio and S-glutathionylated proteins in human blood, solid tissues, and cultured cells 451
Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient 403
Homogentisic acid induces morphological and mechanical aberration of ochronotic cartilage in alkaptonuria 401
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors 399
4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases 397
N-acetylcysteine ethyl ester as GSH enhancer in human primary endothelial cells: A comparative study with other drugs 395
TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration 389
Biochemical and proteomic characterization of alkaptonuric chondrocytes 384
Histological and Ultrastructural Characterization of Alkaptonuric Tissues 375
Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma 373
Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria. 367
Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria 365
CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration 363
Antipeptide monoclonal antibodies inhibit the binding of rabiesvirus glycoprotein and alpha-bungarotoxin to the nicotinic acetylcholine receptor 360
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: preliminary in vitro studies with analogues of immucillin-G 357
Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium 355
A monoclonal antibody to a synthetic fragment of rabies virus glycoprotein binds ligands of the nicotinic cholinergic receptor 352
Beer promotes differentiation and mineralization of human osteoblastic cells: Role of silicon 351
Alkaptonuria is a novel human secondary amyloidogenic disease 347
Establishment of Four New Human Primary Cell Cultures from Chemo-Naïve Italian Osteosarcoma Patients 344
Angiogenesis in alkaptonuria 340
Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project 335
Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste 333
A structural bioinformatics investigation on protein–DNA complexes delineates their modes of interaction 327
Western blotting of total lysate of Helicobacter pylori in cases of atrophic body gastritis. 318
A novel ex vivo organotypic culture model of alkaptonuria-ochronosis 313
A model of the rabies virus glycoprotein active site 312
Diagnosis of secondary amyloidosis in alkaptonuria 302
Different factors affecting human ANP amyloid aggregation and their implications in congestive heart failure 299
Biochemical investigation of the effects of human platelet releasates on human articular chondrocytes 299
Homogentisate 1,2 dioxygenase is expressed in human osteoarticular cells: implications in alkaptonuria. 298
A proteomic study of human osteoblastic cells proliferation and differentiation 298
Long-term effects of neridronate on human osteoblastic cell cultures 297
Cytoskeleton Aberrations in Alkaptonuric Chondrocytes 296
H pylori infection and systemic antibodies to CagA and heat shock protein 60 in patients with coronary heart disease 296
A combined ML and DFT strategy for the prediction of dye candidates for indoor DSSCs 294
A sialoglycoprotein, gp20, of the human capacitated sperm surface is a homologue of the leukocyte CD52: analysis of the effect of anti-CD52 monoclonal antibody (CAMPATH-1) on capacitated spermatozoa 294
The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration 294
Antimicrobial activity against Helicobacter pylori strains and antioxidant properties of blackberry leaves (Rubus ulmifolius) and isolated compounds 293
Quick Diagnosis of Alkaptonuria by Homogentisic Acid Determination in Urine Paper Spots 292
Application of proteomics to the study of Helicobacter pylori and implications for the clinic 292
Yield Determination of Bioethanol Production of Saccharomyces Cerevisiae Metabolic Process by Mathematical Modelling and In-Vivo 13C-NMR 289
Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria 288
Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1,2-dioxygenase mutants at the base of rare disease Alkaptonuria 288
Amyloidosis in alkaptonuria 286
Comparative proteomics in alkaptonuria provides insights into inflammation and oxidative stress 284
Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins 283
A new light on Alkaptonuria: A Fourier-transform infrared microscopy (FTIRM) and low energy X-ray fluorescence (LEXRF) microscopy correlative study on a rare disease 283
An Introduction to Personalized Nutrition 282
High performance liquid chromatography immunoaffinity purification of antibodies and antibody fragments 280
Proteomic investigation of dermal fibroblasts isolated from affected and unaffected skin samples from patients with limited cutaneous systemic sclerosis: 2 distinct entities? 279
Proteomic and redox-proteomic evaluation of homogentisic acid and ascorbic acid effects on human articular chondrocytes 278
Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria 276
Proteomic response to physiological fermentation stresses in a wild-type wine strain of Saccharomyces cerevisiae 275
Wild-type wine Saccharomyces cerevisiae as a tool to evaluate the effects on eukaryotic life of locally used herbicides 271
Interactive alkaptonuria database: investigating clinical data to improve patient care in a rare disease 271
Atrial natriuretic peptide aggregation and its control by plasma factors 270
Modern proteomic methodologies for the characterization of lactosylation protein targets in milk 267
Secondary amyloidosis in an alkaptonuric aortic valve 266
Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease 266
Differentially activated Src kinase in chemo-naive human primary osteosarcoma cells and effects of a Src kinase inhibitor 265
Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria 264
Redox-proteomics of the effects of homogentisic acid in an in vitro human serum model of alkaptonuric ochronosis 263
Evaluation of anti-oxidant treatments in an in vitro model of alkaptonuric ochronosis 262
HIV-1 gp 120 binding to nicotinig receptors 261
Comparative analysis of the effects of locally used herbicides and their active ingredients on a wild-type wine Saccharomyces cerevisiae strain 261
Omicron variants of SARS CoV-2 indicate a new antiviral strategy: Interfere with spike glycoprotein trimerization 260
Affinity purification of rabies virus glycoprotein using immobilized antipeptide antibodies 260
Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’ in Italy 260
Antibacterial activity of grape extracts towards cagA positive and cagA negative Helicobacter pylori clinical isolates 260
Machine learning application for patient stratification and phenotype/genotype investigation in a rare disease 259
Conformations and biological activities of Amyloid Beta Peptide 25-35 257
Antimicrobial Activity of Plant Extracts against Helicobacter pylori 257
Bactericidal activity of grape, soy flour, tomato, and bramble leaf extracts to Helicobacter pylori 256
Homogentisate 1,2 dioxygenase is expressed in brain: implications in alkaptonuria 256
New 4-substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 254
Oxidative stress and mechanisms of ochronosis in alkaptonuria 254
Purification of acidic synthetic peptides by high performance liquid chromatography using ammonium acetate buffer 250
Saccharomyces cerevisiae as a Tool to Evaluate the Effects of Herbicides on Eukaryotic Life 250
Pro-Apoptotic activity of French Polynesian Padina pavonica Extract on Human Osteosarcoma Cells 248
Helicobacter pylori infection and autoimmune thyroid diseases: The role of virulent strains 246
Helicobacter pylori: immunoproteomics related to different pathologies 244
Structure of rubella E1 glycoprotein epitopes established by multiple peptide synthesis 244
Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial 244
Cd93 signaling via rho proteins drives cytoskeletal remodeling in spreading endothelial cells 244
METABOLITE AND PROTEIN PATTERNS IN PLASMA OF LESCH-NYHAN SYNDROME PATIENTS 243
Cloning, characterization, and modeling of a monoclonal anti-human transferrin antibody that competes with the transferrin receptor 243
A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria 242
Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU 241
Mapping phosphoproteins in Neisseria meningitidis serogroup A 240
An antigenic determinant common to human chorionic somatomammotropin and human growth hormone revealed by limited proteolysis of immune complexes 240
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data 239
Negative Helicobacter pylori status is associated with poor prognosis in patients with gastric cancer 239
Animal and cell models for Lesch-Nyhan syndrome 239
AKUImg: A database of cartilage images of Alkaptonuria patients 239
Inactivation of Helicobacter pylori cagA gene affects motility 238
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells. 237
Totale 29.946
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Categoria #
all - tutte 195.584
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 195.584
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.672 0 0 0 0 0 0 0 0 0 767 494 411
2021/20224.619 364 545 340 389 214 178 213 194 272 500 459 951
2022/20236.176 388 583 757 841 649 1.192 144 520 604 165 210 123
2023/20244.643 170 104 476 228 208 1.232 1.473 137 14 59 156 386
2024/20259.698 220 511 946 558 1.161 509 395 615 1.008 395 981 2.399
2025/202622.068 1.797 3.340 3.156 2.902 4.693 936 2.585 686 804 1.169 0 0
Totale 70.074