IRIS
SANTUCCI, ANNALISA
 Distribuzione geografica
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Continente #
NA - Nord America 27.149
EU - Europa 23.138
AS - Asia 10.935
SA - Sud America 1.884
AF - Africa 304
OC - Oceania 43
Continente sconosciuto - Info sul continente non disponibili 21
Totale 63.474
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Nazione #
US - Stati Uniti d'America 26.838
GB - Regno Unito 5.627
RU - Federazione Russa 4.596
CN - Cina 4.099
SG - Singapore 3.620
IT - Italia 2.857
IE - Irlanda 2.807
BR - Brasile 1.623
SE - Svezia 1.605
DE - Germania 1.559
UA - Ucraina 1.498
FR - Francia 1.025
HK - Hong Kong 846
KR - Corea 704
FI - Finlandia 635
VN - Vietnam 473
IN - India 309
TR - Turchia 233
ES - Italia 188
CA - Canada 174
NL - Olanda 130
CI - Costa d'Avorio 121
BE - Belgio 107
AR - Argentina 105
BD - Bangladesh 96
CZ - Repubblica Ceca 93
MX - Messico 93
PL - Polonia 91
JP - Giappone 88
ZA - Sudafrica 76
AT - Austria 64
PK - Pakistan 59
ID - Indonesia 49
IR - Iran 47
IQ - Iraq 40
EC - Ecuador 39
AU - Australia 33
SA - Arabia Saudita 33
EE - Estonia 32
PT - Portogallo 32
AE - Emirati Arabi Uniti 28
CH - Svizzera 26
LT - Lituania 24
UZ - Uzbekistan 24
EG - Egitto 23
IL - Israele 23
PE - Perù 23
AZ - Azerbaigian 22
RO - Romania 22
VE - Venezuela 22
MA - Marocco 21
EU - Europa 20
CO - Colombia 18
PY - Paraguay 18
TN - Tunisia 17
GR - Grecia 15
KE - Kenya 15
CL - Cile 14
KZ - Kazakistan 14
BG - Bulgaria 13
BO - Bolivia 13
DK - Danimarca 13
JO - Giordania 13
HU - Ungheria 12
MY - Malesia 12
KG - Kirghizistan 11
LB - Libano 11
RS - Serbia 10
SK - Slovacchia (Repubblica Slovacca) 10
AM - Armenia 9
DO - Repubblica Dominicana 9
JM - Giamaica 9
NO - Norvegia 9
NZ - Nuova Zelanda 9
TW - Taiwan 9
GE - Georgia 8
PH - Filippine 8
BY - Bielorussia 7
LV - Lettonia 7
NP - Nepal 7
OM - Oman 7
UY - Uruguay 7
AL - Albania 6
ET - Etiopia 6
PA - Panama 6
CR - Costa Rica 5
DZ - Algeria 5
LA - Repubblica Popolare Democratica del Laos 5
LK - Sri Lanka 5
HR - Croazia 4
NG - Nigeria 4
SY - Repubblica araba siriana 4
BH - Bahrain 3
CG - Congo 3
LU - Lussemburgo 3
SN - Senegal 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
HN - Honduras 2
Totale 63.426
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Città #
Southend 4.961
Dallas 3.830
Menlo Park 2.850
Dublin 2.775
Fairfield 2.337
Singapore 2.068
Ashburn 1.841
Chandler 1.792
Moscow 1.236
Jacksonville 1.234
Santa Clara 1.130
Woodbridge 1.060
Siena 979
Beijing 970
Wilmington 950
Houston 868
Hong Kong 826
Seattle 813
Cambridge 753
Ann Arbor 719
Hefei 681
Seoul 680
Princeton 537
Nanjing 441
Los Angeles 366
New York 321
Milan 308
Helsinki 296
Munich 274
Boardman 250
Florence 215
The Dalles 210
San Mateo 198
Shanghai 165
Buffalo 161
Nanchang 154
Izmir 153
São Paulo 145
San Diego 142
Ho Chi Minh City 134
Bengaluru 127
Abidjan 121
Shenyang 121
Dearborn 117
Lancaster 114
Council Bluffs 113
Málaga 109
Rome 106
Dong Ket 105
Fremont 104
Brussels 100
London 98
Columbus 94
Hebei 82
Tianjin 81
Hanoi 75
Redondo Beach 74
Changsha 70
Turku 69
Redwood City 68
Warsaw 67
Kunming 66
Stockholm 64
Frankfurt am Main 62
Tokyo 62
Brooklyn 60
Brno 59
Toronto 58
Rio de Janeiro 57
San Francisco 56
Washington 56
Chicago 55
Johannesburg 54
Denver 53
Jiaxing 51
Phoenix 51
Jinan 50
Guangzhou 48
Atlanta 46
Düsseldorf 46
Norwalk 46
Orem 46
Montreal 45
Vienna 43
Zhengzhou 43
Boston 42
University Park 42
Lappeenranta 41
Venezia 41
Amsterdam 40
Belo Horizonte 40
Brasília 40
Hangzhou 39
Mexico City 38
Nuremberg 38
Poplar 38
Manchester 31
Chennai 29
Ningbo 28
Falls Church 27
Totale 43.669
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Nome #
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 460
Chondroptosis in alkaptonuric cartilage 453
A new integrated and interactive tool applicable to inborn errors of metabolism: Application to alkaptonuria 449
Assessment of glutathione/glutathione disulphide ratio and S-glutathionylated proteins in human blood, solid tissues, and cultured cells 410
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors 378
Homogentisic acid induces morphological and mechanical aberration of ochronotic cartilage in alkaptonuria 376
Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient 373
TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration 365
4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases 356
Histological and Ultrastructural Characterization of Alkaptonuric Tissues 353
Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma 350
Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria. 342
CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration 341
N-acetylcysteine ethyl ester as GSH enhancer in human primary endothelial cells: A comparative study with other drugs 340
Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria 340
Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium 340
A monoclonal antibody to a synthetic fragment of rabies virus glycoprotein binds ligands of the nicotinic cholinergic receptor 332
Beer promotes differentiation and mineralization of human osteoblastic cells: Role of silicon 332
Biochemical and proteomic characterization of alkaptonuric chondrocytes 330
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: preliminary in vitro studies with analogues of immucillin-G 329
Establishment of Four New Human Primary Cell Cultures from Chemo-Naïve Italian Osteosarcoma Patients 322
Antipeptide monoclonal antibodies inhibit the binding of rabiesvirus glycoprotein and alpha-bungarotoxin to the nicotinic acetylcholine receptor 320
Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project 313
Alkaptonuria is a novel human secondary amyloidogenic disease 311
Western blotting of total lysate of Helicobacter pylori in cases of atrophic body gastritis. 309
Angiogenesis in alkaptonuria 298
A structural bioinformatics investigation on protein–DNA complexes delineates their modes of interaction 297
A novel ex vivo organotypic culture model of alkaptonuria-ochronosis 293
A model of the rabies virus glycoprotein active site 293
Long-term effects of neridronate on human osteoblastic cell cultures 286
Different factors affecting human ANP amyloid aggregation and their implications in congestive heart failure 281
H pylori infection and systemic antibodies to CagA and heat shock protein 60 in patients with coronary heart disease 279
Homogentisate 1,2 dioxygenase is expressed in human osteoarticular cells: implications in alkaptonuria. 277
Quick Diagnosis of Alkaptonuria by Homogentisic Acid Determination in Urine Paper Spots 277
A sialoglycoprotein, gp20, of the human capacitated sperm surface is a homologue of the leukocyte CD52: analysis of the effect of anti-CD52 monoclonal antibody (CAMPATH-1) on capacitated spermatozoa 276
Biochemical investigation of the effects of human platelet releasates on human articular chondrocytes 276
Cytoskeleton Aberrations in Alkaptonuric Chondrocytes 275
Diagnosis of secondary amyloidosis in alkaptonuria 275
The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration 274
Yield Determination of Bioethanol Production of Saccharomyces Cerevisiae Metabolic Process by Mathematical Modelling and In-Vivo 13C-NMR 273
Antimicrobial activity against Helicobacter pylori strains and antioxidant properties of blackberry leaves (Rubus ulmifolius) and isolated compounds 273
Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1,2-dioxygenase mutants at the base of rare disease Alkaptonuria 273
Comparative proteomics in alkaptonuria provides insights into inflammation and oxidative stress 271
Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria 270
Application of proteomics to the study of Helicobacter pylori and implications for the clinic 269
A new light on Alkaptonuria: A Fourier-transform infrared microscopy (FTIRM) and low energy X-ray fluorescence (LEXRF) microscopy correlative study on a rare disease 267
An Introduction to Personalized Nutrition 262
Proteomic and redox-proteomic evaluation of homogentisic acid and ascorbic acid effects on human articular chondrocytes 260
High performance liquid chromatography immunoaffinity purification of antibodies and antibody fragments 259
Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste 258
Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins 258
Proteomic investigation of dermal fibroblasts isolated from affected and unaffected skin samples from patients with limited cutaneous systemic sclerosis: 2 distinct entities? 258
Proteomic response to physiological fermentation stresses in a wild-type wine strain of Saccharomyces cerevisiae 257
A proteomic study of human osteoblastic cells proliferation and differentiation 256
Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria 254
Wild-type wine Saccharomyces cerevisiae as a tool to evaluate the effects on eukaryotic life of locally used herbicides 253
Interactive alkaptonuria database: investigating clinical data to improve patient care in a rare disease 253
Secondary amyloidosis in an alkaptonuric aortic valve 252
Modern proteomic methodologies for the characterization of lactosylation protein targets in milk 250
Redox-proteomics of the effects of homogentisic acid in an in vitro human serum model of alkaptonuric ochronosis 250
Differentially activated Src kinase in chemo-naive human primary osteosarcoma cells and effects of a Src kinase inhibitor 248
Evaluation of anti-oxidant treatments in an in vitro model of alkaptonuric ochronosis 247
Atrial natriuretic peptide aggregation and its control by plasma factors 245
Amyloidosis in alkaptonuria 244
Affinity purification of rabies virus glycoprotein using immobilized antipeptide antibodies 242
HIV-1 gp 120 binding to nicotinig receptors 242
A combined ML and DFT strategy for the prediction of dye candidates for indoor DSSCs 241
Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease 241
Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria 241
Comparative analysis of the effects of locally used herbicides and their active ingredients on a wild-type wine Saccharomyces cerevisiae strain 240
New 4-substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 240
Homogentisate 1,2 dioxygenase is expressed in brain: implications in alkaptonuria 240
Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’ in Italy 240
Conformations and biological activities of Amyloid Beta Peptide 25-35 239
Oxidative stress and mechanisms of ochronosis in alkaptonuria 239
Purification of acidic synthetic peptides by high performance liquid chromatography using ammonium acetate buffer 237
Antimicrobial Activity of Plant Extracts against Helicobacter pylori 234
Pro-Apoptotic activity of French Polynesian Padina pavonica Extract on Human Osteosarcoma Cells 234
Omicron variants of SARS CoV-2 indicate a new antiviral strategy: Interfere with spike glycoprotein trimerization 233
Saccharomyces cerevisiae as a Tool to Evaluate the Effects of Herbicides on Eukaryotic Life 232
Machine learning application for patient stratification and phenotype/genotype investigation in a rare disease 232
Helicobacter pylori: immunoproteomics related to different pathologies 230
Structure of rubella E1 glycoprotein epitopes established by multiple peptide synthesis 230
Antibacterial activity of grape extracts towards cagA positive and cagA negative Helicobacter pylori clinical isolates 229
Bactericidal activity of grape, soy flour, tomato, and bramble leaf extracts to Helicobacter pylori 227
Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU 226
Prevalence of isolated atrial amyloidosis in young patients affected by congestive heart failure 224
Mapping phosphoproteins in Neisseria meningitidis serogroup A 223
An antigenic determinant common to human chorionic somatomammotropin and human growth hormone revealed by limited proteolysis of immune complexes 223
METABOLITE AND PROTEIN PATTERNS IN PLASMA OF LESCH-NYHAN SYNDROME PATIENTS 223
Padina pavonica Extract Promotes In Vitro Differentiation and Functionality of Human Primary Osteoblasts 222
HIV-1 and human myelin proteins share an antigenic determinant 221
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells. 220
Effects of selenium on oxidative damage and antioxidant enzymes of eukaryotic cells: wine Saccharomyces cerevisiae 220
Cd93 signaling via rho proteins drives cytoskeletal remodeling in spreading endothelial cells 220
HPLC immunoaffinity purification of rabies virus glycoprotein using immobilized antipeptide antibodies 219
Negative Helicobacter pylori status is associated with poor prognosis in patients with gastric cancer 219
Animal and cell models for Lesch-Nyhan syndrome 219
Proteomics and redox-proteomics of the effects of herbicides on a wild-type wine Saccharomyces cerevisiae strain 218
Suitability of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment 217
Totale 27.618
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Categoria #
all - tutte 184.073
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 184.073
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20214.178 0 0 0 0 0 734 324 817 626 770 496 411
2021/20224.631 365 549 341 389 214 178 214 195 272 500 460 954
2022/20236.198 389 584 759 844 652 1.196 144 521 610 165 210 124
2023/20244.657 170 105 477 228 208 1.236 1.479 137 14 59 156 388
2024/20259.718 222 512 948 559 1.164 511 395 616 1.009 396 983 2.403
2025/202616.064 1.802 3.347 3.162 2.911 4.710 132 0 0 0 0 0 0
Totale 64.221