IRIS
SANTUCCI, ANNALISA
 Distribuzione geografica
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Continente #
NA - Nord America 32.394
EU - Europa 25.884
AS - Asia 13.681
SA - Sud America 2.247
Continente sconosciuto - Info sul continente non disponibili 788
AF - Africa 706
OC - Oceania 47
Totale 75.747
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Nazione #
US - Stati Uniti d'America 31.882
GB - Regno Unito 5.711
IT - Italia 4.794
RU - Federazione Russa 4.585
CN - Cina 4.544
SG - Singapore 4.294
IE - Irlanda 2.803
BR - Brasile 1.805
DE - Germania 1.629
SE - Svezia 1.620
UA - Ucraina 1.504
FR - Francia 1.411
VN - Vietnam 1.287
HK - Hong Kong 990
KR - Corea 711
FI - Finlandia 691
IN - India 442
ZA - Sudafrica 271
CA - Canada 264
TR - Turchia 260
BD - Bangladesh 247
ES - Italia 234
NL - Olanda 179
AR - Argentina 143
PL - Polonia 137
CI - Costa d'Avorio 124
MX - Messico 123
JP - Giappone 121
BE - Belgio 111
NG - Nigeria 110
PK - Pakistan 99
IQ - Iraq 97
CZ - Repubblica Ceca 94
ID - Indonesia 80
AT - Austria 72
EC - Ecuador 72
CO - Colombia 63
VE - Venezuela 53
KE - Kenya 49
SA - Arabia Saudita 49
IR - Iran 48
PT - Portogallo 42
UZ - Uzbekistan 40
AE - Emirati Arabi Uniti 37
AU - Australia 37
EG - Egitto 34
JO - Giordania 34
MY - Malesia 33
EE - Estonia 32
AZ - Azerbaigian 30
LT - Lituania 30
MA - Marocco 30
CH - Svizzera 29
KZ - Kazakistan 29
PH - Filippine 29
CL - Cile 28
PE - Perù 28
TN - Tunisia 28
IL - Israele 27
RO - Romania 25
PY - Paraguay 23
CR - Costa Rica 21
JM - Giamaica 21
BO - Bolivia 20
EU - Europa 20
GR - Grecia 19
NP - Nepal 17
HU - Ungheria 16
LB - Libano 16
BG - Bulgaria 14
OM - Oman 14
RS - Serbia 14
TW - Taiwan 14
DK - Danimarca 13
DZ - Algeria 13
KG - Kirghizistan 13
HN - Honduras 12
NI - Nicaragua 12
SK - Slovacchia (Repubblica Slovacca) 12
AM - Armenia 11
DO - Repubblica Dominicana 11
ET - Etiopia 11
NO - Norvegia 11
TH - Thailandia 11
PA - Panama 10
UY - Uruguay 10
AL - Albania 9
BY - Bielorussia 9
GE - Georgia 9
NZ - Nuova Zelanda 9
HR - Croazia 8
SN - Senegal 8
SY - Repubblica araba siriana 8
TT - Trinidad e Tobago 8
LV - Lettonia 7
AO - Angola 6
CG - Congo 6
GT - Guatemala 6
PS - Palestinian Territory 6
LA - Repubblica Popolare Democratica del Laos 5
Totale 74.888
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Città #
Southend 4.948
Dallas 3.876
Menlo Park 2.842
Dublin 2.768
Singapore 2.463
Ashburn 2.357
Fairfield 2.327
Chandler 1.787
San Jose 1.435
Santa Clara 1.310
Milan 1.289
Jacksonville 1.235
Moscow 1.233
Woodbridge 1.055
Beijing 984
Siena 983
Wilmington 950
Hong Kong 940
Houston 882
Seattle 825
Hefei 814
Council Bluffs 755
Cambridge 750
Ann Arbor 716
Seoul 680
Princeton 536
Los Angeles 488
Nanjing 438
The Dalles 421
Rome 413
New York 394
Ho Chi Minh City 376
Helsinki 353
Lauterbourg 301
Hanoi 285
Munich 272
Florence 265
Boardman 263
Johannesburg 239
San Mateo 197
Buffalo 185
Shanghai 177
São Paulo 165
Columbus 160
Izmir 154
Nanchang 154
Orem 146
San Diego 146
Bengaluru 128
Abidjan 124
Shenyang 121
Dearborn 118
Lancaster 115
London 112
Frankfurt am Main 111
Málaga 109
Warsaw 109
Abuja 105
Dong Ket 105
Brussels 104
Fremont 104
Chicago 97
Tokyo 89
Tianjin 86
Hebei 82
Phoenix 80
Brooklyn 78
Figino 73
Redondo Beach 73
Da Nang 72
Montreal 72
Changsha 71
Toronto 70
Turku 69
Chennai 68
Redwood City 68
Stockholm 67
Amsterdam 66
Atlanta 66
Boston 66
Kunming 66
San Francisco 66
Denver 64
Washington 62
Rio de Janeiro 60
Brno 59
Turin 58
Guangzhou 54
Haiphong 54
Jiaxing 51
Jinan 50
Mexico City 48
Nuremberg 47
Düsseldorf 46
Norwalk 46
Manchester 45
Vienna 45
Belo Horizonte 44
Brasília 44
Mumbai 44
Totale 50.663
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Nome #
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 502
Chondroptosis in alkaptonuric cartilage 501
A new integrated and interactive tool applicable to inborn errors of metabolism: Application to alkaptonuria 496
Assessment of glutathione/glutathione disulphide ratio and S-glutathionylated proteins in human blood, solid tissues, and cultured cells 481
N-acetylcysteine ethyl ester as GSH enhancer in human primary endothelial cells: A comparative study with other drugs 448
Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient 431
4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases 421
Homogentisic acid induces morphological and mechanical aberration of ochronotic cartilage in alkaptonuria 420
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors 416
TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration 407
Biochemical and proteomic characterization of alkaptonuric chondrocytes 405
Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma 390
Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria. 388
Histological and Ultrastructural Characterization of Alkaptonuric Tissues 381
CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration 380
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: preliminary in vitro studies with analogues of immucillin-G 378
Antipeptide monoclonal antibodies inhibit the binding of rabiesvirus glycoprotein and alpha-bungarotoxin to the nicotinic acetylcholine receptor 375
Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium 374
Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria 373
Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste 371
Effects of Nitisinone on Oxidative and Inflammatory Markers in Alkaptonuria: Results from SONIA1 and SONIA2 Studies 368
Beer promotes differentiation and mineralization of human osteoblastic cells: Role of silicon 364
Establishment of Four New Human Primary Cell Cultures from Chemo-Naïve Italian Osteosarcoma Patients 363
A monoclonal antibody to a synthetic fragment of rabies virus glycoprotein binds ligands of the nicotinic cholinergic receptor 362
Alkaptonuria is a novel human secondary amyloidogenic disease 359
Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project 355
Angiogenesis in alkaptonuria 351
A structural bioinformatics investigation on protein–DNA complexes delineates their modes of interaction 342
Western blotting of total lysate of Helicobacter pylori in cases of atrophic body gastritis 337
A novel ex vivo organotypic culture model of alkaptonuria-ochronosis 330
A model of the rabies virus glycoprotein active site 328
Biochemical investigation of the effects of human platelet releasates on human articular chondrocytes 322
A sialoglycoprotein, gp20, of the human capacitated sperm surface is a homologue of the leukocyte CD52: analysis of the effect of anti-CD52 monoclonal antibody (CAMPATH-1) on capacitated spermatozoa 320
A combined ML and DFT strategy for the prediction of dye candidates for indoor DSSCs 319
A proteomic study of human osteoblastic cells proliferation and differentiation 318
Antimicrobial activity against Helicobacter pylori strains and antioxidant properties of blackberry leaves (Rubus ulmifolius) and isolated compounds 317
Diagnosis of secondary amyloidosis in alkaptonuria 316
The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration 316
Different factors affecting human ANP amyloid aggregation and their implications in congestive heart failure 315
Yield Determination of Bioethanol Production of Saccharomyces Cerevisiae Metabolic Process by Mathematical Modelling and In-Vivo 13C-NMR 313
Homogentisate 1,2 dioxygenase is expressed in human osteoarticular cells: implications in alkaptonuria. 313
Application of proteomics to the study of Helicobacter pylori and implications for the clinic 311
Long-term effects of neridronate on human osteoblastic cell cultures 310
Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1,2-dioxygenase mutants at the base of rare disease Alkaptonuria 310
H pylori infection and systemic antibodies to CagA and heat shock protein 60 in patients with coronary heart disease 309
Cytoskeleton Aberrations in Alkaptonuric Chondrocytes 304
High performance liquid chromatography immunoaffinity purification of antibodies and antibody fragments 301
Comparative proteomics in alkaptonuria provides insights into inflammation and oxidative stress 299
Homogentisic acid induces aggregation and fibrillation of amyloidogenic proteins 297
Quick Diagnosis of Alkaptonuria by Homogentisic Acid Determination in Urine Paper Spots 297
An Introduction to Personalized Nutrition 297
A new light on Alkaptonuria: A Fourier-transform infrared microscopy (FTIRM) and low energy X-ray fluorescence (LEXRF) microscopy correlative study on a rare disease 297
Proteomic investigation of dermal fibroblasts isolated from affected and unaffected skin samples from patients with limited cutaneous systemic sclerosis: 2 distinct entities? 296
Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria 294
Wild-type wine Saccharomyces cerevisiae as a tool to evaluate the effects on eukaryotic life of locally used herbicides 291
Amyloidosis in alkaptonuria 291
Modern proteomic methodologies for the characterization of lactosylation protein targets in milk 289
Proteomic and redox-proteomic evaluation of homogentisic acid and ascorbic acid effects on human articular chondrocytes 289
Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria 289
Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease 285
Omicron variants of SARS CoV-2 indicate a new antiviral strategy: Interfere with spike glycoprotein trimerization 284
Proteomic response to physiological fermentation stresses in a wild-type wine strain of Saccharomyces cerevisiae 284
Atrial natriuretic peptide aggregation and its control by plasma factors 283
HIV-1 gp 120 binding to nicotinig receptors 280
Twelve novel HGD gene variants identified in 99 alkaptonuria patients: focus on ‘black bone disease’ in Italy 280
Interactive alkaptonuria database: investigating clinical data to improve patient care in a rare disease 280
Secondary amyloidosis in an alkaptonuric aortic valve 279
Differentially activated Src kinase in chemo-naive human primary osteosarcoma cells and effects of a Src kinase inhibitor 277
Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial 276
Antimicrobial Activity of Plant Extracts against Helicobacter pylori 275
Bactericidal activity of grape, soy flour, tomato, and bramble leaf extracts to Helicobacter pylori 275
New 4-substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 275
Affinity purification of rabies virus glycoprotein using immobilized antipeptide antibodies 274
Machine learning application for patient stratification and phenotype/genotype investigation in a rare disease 274
Evaluation of anti-oxidant treatments in an in vitro model of alkaptonuric ochronosis 274
Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria 274
Conformations and biological activities of Amyloid Beta Peptide 25-35 273
Comparative analysis of the effects of locally used herbicides and their active ingredients on a wild-type wine Saccharomyces cerevisiae strain 273
Redox-proteomics of the effects of homogentisic acid in an in vitro human serum model of alkaptonuric ochronosis 271
Homogentisate 1,2 dioxygenase is expressed in brain: implications in alkaptonuria 270
Antibacterial activity of grape extracts towards cagA positive and cagA negative Helicobacter pylori clinical isolates 270
Oxidative stress and mechanisms of ochronosis in alkaptonuria 268
Mapping phosphoproteins in Neisseria meningitidis serogroup A 264
Metabolite and protein patterns in plasma of Lesch-nyhan syndrome patients 264
Purification of acidic synthetic peptides by high performance liquid chromatography using ammonium acetate buffer 264
Saccharomyces cerevisiae as a Tool to Evaluate the Effects of Herbicides on Eukaryotic Life 264
An antigenic determinant common to human chorionic somatomammotropin and human growth hormone revealed by limited proteolysis of immune complexes 263
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells. 262
Helicobacter pylori infection and autoimmune thyroid diseases: The role of virulent strains 262
Padina pavonica Extract Promotes In Vitro Differentiation and Functionality of Human Primary Osteoblasts 262
Cd93 signaling via rho proteins drives cytoskeletal remodeling in spreading endothelial cells 257
Helicobacter pylori: immunoproteomics related to different pathologies 256
Pro-Apoptotic activity of French Polynesian Padina pavonica Extract on Human Osteosarcoma Cells 256
Alkaptonuria 255
Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU 255
A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria 255
Negative Helicobacter pylori status is associated with poor prognosis in patients with gastric cancer 254
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data 253
Oxidative damage mediated by herbicides on yeast cells 253
Animal and cell models for Lesch-Nyhan syndrome 253
Totale 31.743
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Categoria #
all - tutte 217.471
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 217.471
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.710 0 0 340 389 214 178 213 194 272 500 459 951
2022/20236.176 388 583 757 841 649 1.192 144 520 604 165 210 123
2023/20244.643 170 104 476 228 208 1.232 1.473 137 14 59 156 386
2024/20259.698 220 511 946 558 1.161 509 395 615 1.008 395 981 2.399
2025/202624.955 1.797 3.340 3.156 2.902 4.693 936 2.585 686 804 1.285 605 2.166
2026/20272.786 1.036 736 1.014 0 0 0 0 0 0 0 0 0
Totale 75.747