IRIS
BUTINI, STEFANIA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 15.099
EU - Europa 13.499
AS - Asia 5.836
SA - Sud America 916
AF - Africa 156
OC - Oceania 34
Continente sconosciuto - Info sul continente non disponibili 15
AN - Antartide 1
Totale 35.556
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 14.891
GB - Regno Unito 3.120
RU - Federazione Russa 2.873
CN - Cina 2.257
IT - Italia 2.184
SG - Singapore 1.798
IE - Irlanda 1.561
SE - Svezia 837
DE - Germania 828
BR - Brasile 753
UA - Ucraina 739
FR - Francia 474
HK - Hong Kong 451
FI - Finlandia 322
KR - Corea 298
VN - Vietnam 278
IN - India 202
TR - Turchia 162
CA - Canada 121
ES - Italia 110
NL - Olanda 71
AR - Argentina 64
AT - Austria 61
BD - Bangladesh 59
MX - Messico 55
PL - Polonia 54
CZ - Repubblica Ceca 52
JP - Giappone 51
ZA - Sudafrica 44
BE - Belgio 43
CI - Costa d'Avorio 42
IQ - Iraq 30
IR - Iran 30
RO - Romania 30
GR - Grecia 24
PK - Pakistan 24
EC - Ecuador 23
MA - Marocco 23
AU - Australia 22
ID - Indonesia 21
SA - Arabia Saudita 20
UZ - Uzbekistan 20
LT - Lituania 19
VE - Venezuela 18
EG - Egitto 17
IL - Israele 17
AZ - Azerbaigian 14
CO - Colombia 14
PT - Portogallo 14
CH - Svizzera 13
AE - Emirati Arabi Uniti 12
CL - Cile 12
JO - Giordania 12
PE - Perù 11
EU - Europa 10
EE - Estonia 9
KZ - Kazakistan 9
NZ - Nuova Zelanda 9
BO - Bolivia 8
DK - Danimarca 8
JM - Giamaica 8
KG - Kirghizistan 8
LV - Lettonia 8
TN - Tunisia 8
PY - Paraguay 7
BG - Bulgaria 6
ET - Etiopia 6
HU - Ungheria 6
KE - Kenya 6
NP - Nepal 6
PA - Panama 6
RS - Serbia 6
GE - Georgia 5
LA - Repubblica Popolare Democratica del Laos 5
MY - Malesia 5
SY - Repubblica araba siriana 5
CR - Costa Rica 4
HN - Honduras 4
LB - Libano 4
MC - Monaco 4
NO - Norvegia 4
OM - Oman 4
PH - Filippine 4
TH - Thailandia 4
TW - Taiwan 4
UY - Uruguay 4
XK - ???statistics.table.value.countryCode.XK??? 4
AM - Armenia 3
AO - Angola 3
BA - Bosnia-Erzegovina 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
KW - Kuwait 3
LK - Sri Lanka 3
MD - Moldavia 3
AL - Albania 2
BB - Barbados 2
BN - Brunei Darussalam 2
DZ - Algeria 2
GY - Guiana 2
Totale 35.527
Salva come PNG Salva come JPEG
Città #
Southend 2.794
Dallas 2.138
Fairfield 1.754
Dublin 1.546
Ashburn 1.395
Singapore 982
Woodbridge 789
Chandler 787
Siena 730
Moscow 721
Seattle 660
Wilmington 643
Santa Clara 641
Beijing 622
Houston 613
Cambridge 603
Jacksonville 603
Hong Kong 450
Ann Arbor 443
Hefei 328
Seoul 291
Princeton 264
Los Angeles 227
Nanjing 210
New York 209
Milan 161
Dearborn 146
Florence 144
Helsinki 128
Munich 126
Fremont 115
Izmir 115
Boardman 109
Shanghai 104
Rome 95
The Dalles 92
Bengaluru 91
San Diego 88
San Mateo 84
Ho Chi Minh City 81
Washington 79
Buffalo 75
Nanchang 74
São Paulo 73
Düsseldorf 60
Lappeenranta 58
London 56
Málaga 56
Hanoi 52
Lancaster 49
Hebei 46
Tokyo 46
Council Bluffs 44
Abidjan 42
Brno 42
Guangzhou 42
Shenyang 40
Warsaw 40
Denver 39
Jiaxing 39
Vienna 39
Columbus 37
Redondo Beach 37
Brussels 36
Redwood City 35
Aachen 34
Jinan 34
Brooklyn 33
Changsha 33
Kunming 33
San Francisco 33
Tianjin 33
Frankfurt am Main 32
Norwalk 31
Nuremberg 31
Johannesburg 30
Venezia 30
Atlanta 29
Montreal 29
Toronto 29
Orem 28
Portsmouth 28
Turku 28
Menlo Park 26
Ottawa 26
Phoenix 26
Poplar 26
Stockholm 26
Ningbo 25
Belo Horizonte 24
Chennai 24
Dong Ket 23
Lauterbourg 23
Rio de Janeiro 23
Boston 22
Mexico City 20
Naples 20
Tashkent 20
Pisa 19
Berlin 18
Totale 24.307
Salva come PNG Salva come JPEG
Nome #
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation 404
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 380
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 371
Development of novel cyclic peptides as pro-apoptotic agents 369
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 360
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 354
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 341
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 331
A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin 307
Synthetic spirocyclic endoperoxides: new antimalarial scaffolds 304
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 303
Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation 303
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 300
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis 296
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 295
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 295
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 293
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 292
Identification of novel fluorescent probes preventing PrP(Sc) replication in prion diseases 284
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 284
Unveiling Wound Healing Properties of Biostimulated Walnut Kernel Extracts via Epithelial Mesenchymal Transition: Switching a Nutritional Matrix into a Therapeutic Remedy 283
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 281
1H-Cyclopentapyrimidine-2,4(1H,3H)-dione-Related Ionotropic Glutamate Receptors Ligands. Structure-Activity Relationships and Identification of Potent and Selective iGluR5 Modulators 278
Natural Compounds and Synthetic Drugs to Target FAAH Enzyme 278
A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues 277
The 1-(2,3-dichlorophenyl)-piperazine-to-aripiprazole ratio at steady state in rats and schizophrenic patients 274
A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides 270
A stereoselective approach to peptidomimetic BACE1 inhibitors 270
Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies 268
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine d3 and serotonin 5-HT 1A and 5-HT2A receptors: Design, synthesis, and effects on behavior 260
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 259
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 258
Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling 254
Old but gold: tracking the new guise of Histone Deacetylase 6 (HDAC6) enzyme as a biomarker and therapeutic target in rare diseases 253
Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors 252
Novel quinolone-based potent and selective HDAC6 inhibitors: synthesis, molecular modeling studies and biological investigation 252
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents 251
A palladium-catalyzed synthetic approach to new Huperzine A analogues modified at the pyridone ring 250
Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents 248
Telomerase-based cancer therapeutics: a review on their clinical trials 248
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 248
Non-Nucleoside Inhibitors of Human Adenosine Kinase: Synthesis, Molecular Modeling, and Biological Studies 247
Discovery of Potent Inhibitors of Human and Mouse Fatty Acid Amide Hydrolases 247
Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boride reduction: a convenient approach to 4-aminoquinolines and derivatives 244
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 243
Development of Antitubercular Compounds Based on a 4-Quinolylhydrazone Scaffold. Further Structure-activity Relationship Studies 241
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) 241
An efficient approach to chiral C8/C9-Piperazino-Substituted 1,4-Benzodiazepin-2-ones as peptidomimetic scaffolds 236
Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors 235
Synthetic studies toward 1,2-dioxanes as precursors of potential endoperoxide-containing antimalarials 232
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents 231
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 230
Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore 230
Discovery of Bishomo(hetero)arylpiperazines as Novel Multifunctional Ligands Targeting Dopamine D-3 and Serotonin 5-HT1A and 5-HT2A Receptors 229
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 228
Synthesis of Dihydroplakortin, 6-epi-Dihydroplakortin, and Their C10-Desethyl Analogues 227
Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663 226
Discovery of Huperzine A/Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Mid-gorge Recognition Sites 223
Synthesis and structure–activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 223
'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one 222
Pyrrolo 1,3 benzothiazepine-based Atypical Antipsychotic Agents. Synthesis, Structure-Activity Relationship, Molecular Modeling, and Biological Studies 221
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy 221
Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological Studies 220
Synthesis and Antiplasmodial Activity of Bicyclic Dioxanes as Simplified Dihydroplakortin Analogues 219
Malaria chemotherapy: recent advances in drug development 218
Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and Pharmacological and Biostructural Characterization 218
Novel aryl piperazine derivatives with medical utility 217
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells 217
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling 217
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors 216
The Interactions of the 5-HT3 Receptor with Quipazine-Like Arylpiperazine Ligands. The Journey Track at the End of the First Decade of the Third Millennium 215
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 215
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders 215
A Straightforward Approach for Engineering Efficacy and Selectivity at GPCRs 214
The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity 214
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 212
Disease modifying anti-Alzheimer’s drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregation 212
Retinitis pigmentosa and retinal degenerations: deciphering pathways and targets for drug discovery and development 212
ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS. 211
Computational tool for fast in silico evaluation of hERG K+ channel affinity 210
Screening and phenotypical characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) inhibitors as multistage antischistosomal agents 210
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 209
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations 209
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation 208
Raising the bar in anticancer therapy: recent advances in, and perspectives on, telomerase inhibitors 206
Synthetic studies toward bicyclic endoperoxides presenting polar side chains 203
Specific Targeting of Peripheral Serotonin 5-HT3 Receptors. Synthesis, Biological Investigation and Structure Activity Relationships 200
Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas 199
Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains 198
Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants 198
Pyrroloquinoxaline hydrazones as fluorescent probes for amyloid fibrils 195
null 195
Pyrrolo[1,5]benzoxa(thia)zepines as a New Class of Potent Apoptotic Agents. Biological Studies and Identification of an Intracellular Location of Their Drug Target 194
Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity 193
Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties 191
Development of a multiplexed activity-based protein profiling assay to evaluate activity of endocannabinoid hydrolase inhibitors 191
Multifunctional Cholinesterase and Amyloid Beta Fibrillization Modulators. Synthesis and Biological Investigation 190
Clotrimazole Scaffold as an Innovative Pharmacophore Towards Potent Antimalarial Agents: Design, Synthesis, Biological and Structure-Activity Relationship Studies 189
Neuronal high affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases 188
Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats 188
Totale 24.681
Salva come PNG Salva come JPEG
Categoria #
all - tutte 106.228
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 106.228
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.709 0 0 0 0 0 609 331 463 322 475 317 192
2021/20222.602 229 307 226 156 123 73 133 111 123 330 294 497
2022/20233.081 178 302 415 392 337 602 89 242 277 100 93 54
2023/20242.984 107 55 276 137 183 797 895 42 30 99 124 239
2024/20255.393 165 223 658 303 620 297 173 282 616 250 490 1.316
2025/20269.248 972 1.721 1.875 1.698 2.599 383 0 0 0 0 0 0
Totale 36.117