IRIS
BALDARI, COSIMA
 Distribuzione geografica
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Continente #
NA - Nord America 22.494
EU - Europa 17.378
AS - Asia 9.194
SA - Sud America 1.430
AF - Africa 437
OC - Oceania 31
Continente sconosciuto - Info sul continente non disponibili 25
Totale 50.989
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Nazione #
US - Stati Uniti d'America 22.240
GB - Regno Unito 4.351
CN - Cina 3.254
RU - Federazione Russa 3.144
SG - Singapore 2.795
IE - Irlanda 2.283
IT - Italia 2.131
SE - Svezia 1.326
BR - Brasile 1.195
UA - Ucraina 1.133
VN - Vietnam 957
FR - Francia 935
DE - Germania 862
HK - Hong Kong 719
FI - Finlandia 571
KR - Corea 499
IN - India 239
ZA - Sudafrica 174
ES - Italia 120
CA - Canada 119
NL - Olanda 112
BD - Bangladesh 103
AR - Argentina 86
IQ - Iraq 80
TR - Turchia 79
NG - Nigeria 78
BE - Belgio 74
MX - Messico 72
JP - Giappone 67
CI - Costa d'Avorio 66
AT - Austria 52
CH - Svizzera 47
PL - Polonia 46
CZ - Repubblica Ceca 44
SA - Arabia Saudita 44
ID - Indonesia 42
PK - Pakistan 40
IR - Iran 38
EC - Ecuador 32
VE - Venezuela 32
UZ - Uzbekistan 30
KE - Kenya 27
CO - Colombia 26
EU - Europa 25
IL - Israele 25
LT - Lituania 24
AE - Emirati Arabi Uniti 23
AU - Australia 22
MA - Marocco 21
GR - Grecia 20
JO - Giordania 19
EG - Egitto 17
PA - Panama 17
TN - Tunisia 17
MY - Malesia 16
PH - Filippine 16
CL - Cile 15
DZ - Algeria 14
PE - Perù 13
KG - Kirghizistan 12
UY - Uruguay 12
AZ - Azerbaigian 11
KZ - Kazakistan 11
PT - Portogallo 11
PY - Paraguay 11
NP - Nepal 10
DO - Repubblica Dominicana 9
SK - Slovacchia (Repubblica Slovacca) 8
CR - Costa Rica 7
GE - Georgia 7
HN - Honduras 7
HU - Ungheria 7
JM - Giamaica 7
NZ - Nuova Zelanda 7
RO - Romania 7
AL - Albania 6
BY - Bielorussia 6
ET - Etiopia 6
LK - Sri Lanka 6
LU - Lussemburgo 6
NI - Nicaragua 6
OM - Oman 6
BO - Bolivia 5
DK - Danimarca 5
LB - Libano 5
NO - Norvegia 5
RS - Serbia 5
AM - Armenia 4
BA - Bosnia-Erzegovina 4
BH - Bahrain 4
GA - Gabon 4
HR - Croazia 4
LA - Repubblica Popolare Democratica del Laos 4
LV - Lettonia 4
MK - Macedonia 4
TH - Thailandia 4
TT - Trinidad e Tobago 4
AO - Angola 3
CY - Cipro 3
EE - Estonia 3
Totale 50.928
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Città #
Southend 3.865
Dallas 3.575
Dublin 2.253
Fairfield 1.983
Ashburn 1.706
Singapore 1.701
Menlo Park 1.598
Chandler 1.205
Santa Clara 954
Woodbridge 953
Jacksonville 926
Moscow 850
Wilmington 821
Seattle 795
Beijing 746
Houston 713
Hong Kong 688
Cambridge 669
Ann Arbor 652
Hefei 634
San Jose 598
Siena 585
Seoul 488
Princeton 376
The Dalles 330
Nanjing 318
Helsinki 305
Los Angeles 291
Ho Chi Minh City 268
Florence 233
Lauterbourg 231
New York 223
Council Bluffs 209
Hanoi 190
Dong Ket 176
Venezia 168
Milan 161
Dearborn 156
Johannesburg 148
Munich 146
Boardman 137
Shanghai 133
Buffalo 128
San Diego 119
San Mateo 106
São Paulo 106
Nanchang 92
Shenyang 91
London 88
Bengaluru 87
Fremont 80
Rome 78
Orem 77
Abuja 75
Málaga 75
Columbus 74
Lancaster 68
Abidjan 66
Brussels 65
Frankfurt am Main 61
Kunming 60
Lappeenranta 57
Tianjin 54
San Francisco 52
Tokyo 50
Chennai 48
Düsseldorf 47
Rio de Janeiro 47
Haiphong 46
Hebei 46
Amsterdam 45
Jinan 45
Phoenix 45
Redondo Beach 43
Changsha 42
Nuremberg 41
Turku 40
Warsaw 40
Guangzhou 38
Chicago 37
Norwalk 37
Belo Horizonte 36
Jiaxing 36
Zhengzhou 35
Redwood City 34
Toronto 34
Brno 33
Washington 33
Vienna 32
Brasília 31
Montreal 31
Da Nang 30
Brooklyn 29
Tashkent 29
Dhaka 28
Atlanta 27
Izmir 27
Ningbo 27
Denver 25
Baghdad 24
Totale 36.234
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Nome #
Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles 1.170
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T cell antigen receptor signaling to Ras family GTPases and Myc dependent survival 631
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape 388
Development of novel cyclic peptides as pro-apoptotic agents 384
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 364
A T cell suppressive circuitry mediated by CD39 and regulated by ShcC/RAI is induced in astrocytes by encephalitogenic T cells 355
Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment 344
Phase Ib study of poly-epitope peptide vaccination to thymidylate synthase (TSPP) and GOLFIG chemo-immunotherapy for treatment of metastatic colorectal cancer patients 333
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 330
Analysis of TCR/CD3 recycling at the immune synapse 330
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly 328
The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases 327
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system 324
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis 316
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 310
Anthrax toxins suppress T-lymphocyte activation by disrupting antigen receptor signaling. 301
A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly 300
Compartmentalized cyclic AMP production by the Bordetella pertussis and Bacillus anthracis adenylate cyclase toxins differentially affects the immune synapse in T lymphocytes 298
Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells 297
The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis 295
Colchicine myopathy and neuromyopathy: two cases with different characteristics 294
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 293
The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse 291
Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia 289
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia 289
The T cell IFT20 interactome reveals new players in immune synapse assembly 287
An apical actin-rich domain drives the establishment of cell polarity during cell adhesion. 286
The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells 281
Validation of a diagnostic score for the diagnosis of autoinflammatory diseases in adults 280
The Shc protein Rai enhances T-cell survival under hypoxia 278
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia 275
Altered balance of helper T cells in Rai-/- mice 274
Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway 271
F-actin dynamics controls segregation of the TCR signaling cascade to clustered lipid rafts 270
A Ciliary View of the Immunological Synapse 270
Intraflagellar transport: a new player at the immune synapse. 269
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes 269
Astrocyte deficiency of the Shc family member Rai attenuates myelin-reactive Th17 cell-dependent neurodegeneration in EAE: a mechanistic study of astrocyte-T cell interactions 268
An intraflagellar transport component is required for polarized recycling of the TCR/CD3 complex to the immune synapse 266
p66Shc promotes T-cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis 265
The Rab GTPase Rab8 as a shared regulator of ciliogenesis and immune synapse assembly: from a conserved pathway to diverse cellular structures 264
p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics 260
IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo 259
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) 259
Human cytotoxic T lymphocytes form dysfunctional immune synapses with B cells characterized by non-polarized lytic granule release 257
Lack of p66Shc in the CLL mouse model E mu-TCL1 exacerbates nodal and extranodal infiltration of leukemic cells which can undergo Richter's transformation 253
Dysfunctional immune synapses in T cell immunodeficiencies 252
Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells 249
The immune synapse: Past, present, and future 249
Anthrax toxins: a paradigm of bacterial immune suppression 249
The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of Th17 cell development 248
Altered balance of helper T cells in Rai-/- mice 247
Anthrax toxins inhibit immune cell chemotaxis 246
The adaptor protein p66shc is a positive regulator in the angiogenic response induced by hypoxic T cells 244
T cell costimulation by the hepatitis C virus envelope protein E2 binding to CD81 is mediated by Lck 241
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T-cells 240
The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity 240
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 240
Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters 239
The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II 239
Hypoxia and immune surveillance: role of the adaptor protein p66ShcA in negative regulation of T-cell activation and survival ' 237
Antigen receptor signaling under the tuscan sun 236
The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development 236
Src family kinases regulate interferon regulatory factor 1 K63 ubiquitination following activation by TLR7/8 vaccine adjuvant in human monocytes and B cells 236
Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia 235
Simvastatin inhibits T cell activation by selectively impairing the function of RAS superfamily GTPases 234
B cell development: COX-1 joins the game 234
Regulation of T Cell Activation and Differentiation by Extracellular Vesicles and Their Pathogenic Role in Systemic Lupus Erythematosus and Multiple Sclerosis 233
Transcellular communication at the immunological synapse: A vesicular traffic-mediated mutual exchange 232
Intrinsic factor recognition promotes T helper 17/T helper 1 autoimmune gastric inflammation in patients with pernicious anemia 231
Vesicular trafficking to the immune synapse: How to assemble receptor-tailored pathways from a basic building set 230
First report of circulating microRNAs in tumour necrosis factor receptor-associated periodic syndrome (TRAPS). 229
The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation. 229
Astrocytic ShcC/Rai supports the function of autoreactive T cells during EAE by modulating adenosine-dependent CTLA4 expression through the inhibition of CD39 and CD73 activity 228
Statins and the joint: multiple targets for a global protection? 227
ZAP-70. AfCS-Nature Molecule Pages 225
Regulation of vesicular traffic at the T cell immune synapse: lessons from the primary cilium 225
Anthax toxins: a weapon to systematically dismantle the host immune defenses. 224
Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium 224
Signals controlling lytic granule polarization at the cytotoxic immune synapse 224
Neisseria meningitidis subverts the polarized organization and intracellular trafficking of host cells to cross the epithelial barrier 222
Boosting chemokine receptor recycling: An elixir of life for chronic lymphocytic leukemia 222
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis 220
Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis 219
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays 219
Nonsteroidal anti-inflammatory drugs inhibit a Fyn dependent pathway coupled to Rac and stress kinase activation in TCR signaling 218
The B-side of the immune response 218
p66Shc: the apoptotic side of Shc proteins 217
The CXCL12/CXCR4 Axis as a Therapeutic Target in Cancer and HIV-1 Infection 217
Regulation of Selective B Cell Autophagy by the Pro-oxidant Adaptor p66SHC 216
Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse 215
Systemic-onset juvenile idiopathic arthritis complicated by early onset amyloidosis in a patient carrying a mutation in the MEFV gene 214
Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus 212
The possible role of T cells and neutrophils in the regulation of tumour angiogenesis 212
Development and preliminary validation of a diagnostic score for identifying patients affected with adult-onset autoinflammatory disorders 212
Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering 211
Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases. 210
Simvastatin impairs humoral and cell-mediated immunity in mice by inhibiting lymphocyte homing, T-cell activation and antigen cross-presentation. 210
Defective Vav expression and impaired F-actin reorganization in a subset of common variable immunodeficiency patients with T-cell defects 210
Lymphocyte Polarization During Immune Synapse Assembly: Centrosomal Actin Joins the Game 209
Totale 27.177
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Categoria #
all - tutte 150.489
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 150.489
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.258 0 0 0 0 0 0 0 0 0 468 408 382
2021/20223.284 233 377 161 425 223 98 168 153 158 310 345 633
2022/20234.650 296 468 598 642 453 913 89 358 457 125 158 93
2023/20244.053 135 67 377 184 158 975 1.221 408 20 97 93 318
2024/20256.637 166 387 589 380 876 475 186 425 441 272 674 1.766
2025/202615.521 1.334 3.595 1.874 1.752 3.005 465 1.826 418 581 671 0 0
Totale 51.587