IRIS
BALDARI, COSIMA
 Distribuzione geografica
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Continente #
NA - Nord America 24.737
EU - Europa 19.237
AS - Asia 9.685
SA - Sud America 1.497
Continente sconosciuto - Info sul continente non disponibili 637
AF - Africa 451
OC - Oceania 34
Totale 56.278
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Nazione #
US - Stati Uniti d'America 24.421
GB - Regno Unito 4.495
IT - Italia 3.425
CN - Cina 3.412
RU - Federazione Russa 3.278
SG - Singapore 2.957
IE - Irlanda 2.362
SE - Svezia 1.365
BR - Brasile 1.245
UA - Ucraina 1.184
VN - Vietnam 1.000
FR - Francia 971
DE - Germania 892
HK - Hong Kong 759
FI - Finlandia 589
KR - Corea 517
IN - India 255
ZA - Sudafrica 180
CA - Canada 154
ES - Italia 127
BD - Bangladesh 125
NL - Olanda 118
AR - Argentina 91
TR - Turchia 83
IQ - Iraq 82
BE - Belgio 78
NG - Nigeria 78
MX - Messico 77
JP - Giappone 76
CI - Costa d'Avorio 66
AT - Austria 53
CH - Svizzera 52
PL - Polonia 48
SA - Arabia Saudita 46
CZ - Repubblica Ceca 45
ID - Indonesia 42
PK - Pakistan 42
IR - Iran 41
EC - Ecuador 35
VE - Venezuela 33
KE - Kenya 32
UZ - Uzbekistan 31
CO - Colombia 28
AE - Emirati Arabi Uniti 25
AU - Australia 25
EU - Europa 25
IL - Israele 25
LT - Lituania 24
MA - Marocco 21
GR - Grecia 20
CL - Cile 19
JO - Giordania 19
EG - Egitto 18
PA - Panama 18
TN - Tunisia 18
MY - Malesia 16
PH - Filippine 16
CR - Costa Rica 14
DZ - Algeria 14
PE - Perù 14
KG - Kirghizistan 12
KZ - Kazakistan 12
PT - Portogallo 12
UY - Uruguay 12
AZ - Azerbaigian 11
PY - Paraguay 11
DO - Repubblica Dominicana 10
JM - Giamaica 10
NP - Nepal 10
HN - Honduras 9
DK - Danimarca 8
GE - Georgia 8
SK - Slovacchia (Repubblica Slovacca) 8
HU - Ungheria 7
NZ - Nuova Zelanda 7
OM - Oman 7
RO - Romania 7
RS - Serbia 7
AL - Albania 6
BO - Bolivia 6
BY - Bielorussia 6
ET - Etiopia 6
LK - Sri Lanka 6
LU - Lussemburgo 6
NI - Nicaragua 6
TT - Trinidad e Tobago 6
GT - Guatemala 5
LA - Repubblica Popolare Democratica del Laos 5
LB - Libano 5
NO - Norvegia 5
AM - Armenia 4
BA - Bosnia-Erzegovina 4
BG - Bulgaria 4
BH - Bahrain 4
GA - Gabon 4
HR - Croazia 4
KH - Cambogia 4
KW - Kuwait 4
LV - Lettonia 4
MK - Macedonia 4
Totale 55.597
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Città #
Southend 3.988
Dallas 3.709
Dublin 2.330
Ashburn 2.042
Fairfield 1.992
Singapore 1.785
Menlo Park 1.613
Chandler 1.254
Santa Clara 1.063
Jacksonville 971
Woodbridge 957
San Jose 931
Moscow 883
Milan 871
Wilmington 833
Seattle 800
Beijing 783
Hong Kong 725
Houston 723
Cambridge 671
Ann Arbor 665
Hefei 656
Siena 598
Seoul 506
Council Bluffs 483
Princeton 386
The Dalles 361
Nanjing 335
Los Angeles 326
Helsinki 310
Rome 291
Ho Chi Minh City 284
New York 260
Florence 249
Lauterbourg 240
Hanoi 204
Dong Ket 176
Venezia 170
Dearborn 156
Johannesburg 153
Munich 149
Boardman 143
Shanghai 139
Buffalo 136
Columbus 130
San Diego 125
São Paulo 112
San Mateo 108
Nanchang 97
Shenyang 96
London 91
Bengaluru 89
Fremont 81
Orem 80
Málaga 76
Abuja 75
Lancaster 72
Brussels 67
Abidjan 66
Frankfurt am Main 64
Kunming 62
Phoenix 61
Lappeenranta 59
Tianjin 56
Figino 55
San Francisco 53
Tokyo 52
Chennai 50
Hebei 49
Rio de Janeiro 49
Haiphong 48
Düsseldorf 47
Chicago 46
Redondo Beach 46
Amsterdam 45
Changsha 45
Jinan 45
Turku 43
Guangzhou 41
Norwalk 41
Nuremberg 41
Toronto 41
Warsaw 41
Turin 38
Jiaxing 37
Belo Horizonte 36
Montreal 36
Zhengzhou 36
Atlanta 35
Redwood City 34
Washington 34
Brno 33
Brooklyn 33
Da Nang 32
Denver 32
Vienna 32
Brasília 31
Dhaka 30
Tashkent 30
Izmir 28
Totale 39.412
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Nome #
Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles 1.192
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T cell antigen receptor signaling to Ras family GTPases and Myc dependent survival 639
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape 395
Development of novel cyclic peptides as pro-apoptotic agents 392
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 375
A T cell suppressive circuitry mediated by CD39 and regulated by ShcC/RAI is induced in astrocytes by encephalitogenic T cells 369
Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment 354
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 347
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system 345
The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases 344
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 344
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis 342
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly 341
Analysis of TCR/CD3 recycling at the immune synapse 340
Phase Ib study of poly-epitope peptide vaccination to thymidylate synthase (TSPP) and GOLFIG chemo-immunotherapy for treatment of metastatic colorectal cancer patients 339
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 321
A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly 318
The T cell IFT20 interactome reveals new players in immune synapse assembly 316
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes 316
Compartmentalized cyclic AMP production by the Bordetella pertussis and Bacillus anthracis adenylate cyclase toxins differentially affects the immune synapse in T lymphocytes 315
Anthrax toxins suppress T-lymphocyte activation by disrupting antigen receptor signaling 310
The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis 309
Colchicine myopathy and neuromyopathy: two cases with different characteristics 308
Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells 308
The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse 304
An apical actin-rich domain drives the establishment of cell polarity during cell adhesion 302
Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia 300
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia 297
Validation of a diagnostic score for the diagnosis of autoinflammatory diseases in adults 296
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia 296
The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells 293
Intraflagellar transport: a new player at the immune synapse. 285
Altered balance of helper T cells in Rai-/- mice 284
The Shc protein Rai enhances T-cell survival under hypoxia 282
An intraflagellar transport component is required for polarized recycling of the TCR/CD3 complex to the immune synapse 281
Astrocyte deficiency of the Shc family member Rai attenuates myelin-reactive Th17 cell-dependent neurodegeneration in EAE: a mechanistic study of astrocyte-T cell interactions 281
F-actin dynamics controls segregation of the TCR signaling cascade to clustered lipid rafts 279
The Rab GTPase Rab8 as a shared regulator of ciliogenesis and immune synapse assembly: from a conserved pathway to diverse cellular structures 279
A Ciliary View of the Immunological Synapse 279
Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway 278
p66Shc promotes T-cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis 278
p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics 276
Human cytotoxic T lymphocytes form dysfunctional immune synapses with B cells characterized by non-polarized lytic granule release 274
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) 273
Dysfunctional immune synapses in T cell immunodeficiencies 271
Lack of p66Shc in the CLL mouse model E mu-TCL1 exacerbates nodal and extranodal infiltration of leukemic cells which can undergo Richter's transformation 268
An AMBRA1, ULK1 and PP2A regulatory network regulates cytotoxic T cell differentiation via TFEB activation 267
IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo 264
Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells 262
The adaptor protein p66shc is a positive regulator in the angiogenic response induced by hypoxic T cells 262
The immune synapse: Past, present, and future 262
Altered balance of helper T cells in Rai-/- mice 260
Anthrax toxins: a paradigm of bacterial immune suppression 259
The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of Th17 cell development 256
T cell costimulation by the hepatitis C virus envelope protein E2 binding to CD81 is mediated by Lck 255
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T-cells 253
Anthrax toxins inhibit immune cell chemotaxis 252
Hypoxia and immune surveillance: role of the adaptor protein p66ShcA in negative regulation of T-cell activation and survival ' 251
Src family kinases regulate interferon regulatory factor 1 K63 ubiquitination following activation by TLR7/8 vaccine adjuvant in human monocytes and B cells 251
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 250
The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity 249
The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II 249
Intrinsic factor recognition promotes T helper 17/T helper 1 autoimmune gastric inflammation in patients with pernicious anemia 249
Simvastatin inhibits T cell activation by selectively impairing the function of RAS superfamily GTPases 248
Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters 248
Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia 248
ZAP-70. AfCS-Nature Molecule Pages 246
Transcellular communication at the immunological synapse: A vesicular traffic-mediated mutual exchange 245
Anthax toxins: a weapon to systematically dismantle the host immune defenses 244
First report of circulating microRNAs in tumour necrosis factor receptor-associated periodic syndrome (TRAPS). 244
The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development 242
Boosting chemokine receptor recycling: An elixir of life for chronic lymphocytic leukemia 242
Antigen receptor signaling under the tuscan sun 241
Regulation of T Cell Activation and Differentiation by Extracellular Vesicles and Their Pathogenic Role in Systemic Lupus Erythematosus and Multiple Sclerosis 241
B cell development: COX-1 joins the game 239
The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation 239
Astrocytic ShcC/Rai supports the function of autoreactive T cells during EAE by modulating adenosine-dependent CTLA4 expression through the inhibition of CD39 and CD73 activity 239
Vesicular trafficking to the immune synapse: How to assemble receptor-tailored pathways from a basic building set 238
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays 237
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis 236
Regulation of Selective B Cell Autophagy by the Pro-oxidant Adaptor p66SHC 236
Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis 235
Signals controlling lytic granule polarization at the cytotoxic immune synapse 235
Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium 234
Regulation of vesicular traffic at the T cell immune synapse: lessons from the primary cilium 233
Nonsteroidal anti-inflammatory drugs inhibit a Fyn dependent pathway coupled to Rac and stress kinase activation in TCR signaling 233
Statins and the joint: multiple targets for a global protection? 231
The B-side of the immune response 231
The CXCL12/CXCR4 Axis as a Therapeutic Target in Cancer and HIV-1 Infection 230
Systemic-onset juvenile idiopathic arthritis complicated by early onset amyloidosis in a patient carrying a mutation in the MEFV gene 228
The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells 228
Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse 228
Neisseria meningitidis subverts the polarized organization and intracellular trafficking of host cells to cross the epithelial barrier 225
p66Shc: the apoptotic side of Shc proteins 223
Simvastatin impairs humoral and cell-mediated immunity in mice by inhibiting lymphocyte homing, T-cell activation and antigen cross-presentation 223
Development and preliminary validation of a diagnostic score for identifying patients affected with adult-onset autoinflammatory disorders 223
Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering 223
Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus 221
Expression in T-cells of the proapoptotic protein p66SHC is controlled by promoter demethylation 221
Immune-inflammatory markers predict the outcome of metastatic colorectal cancer patients treated with the thymidylate synthase poly-epitope peptide (TSPP) vaccine: results from a multi-arm TSPP/VAC phase lb program 221
Totale 28.565
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Categoria #
all - tutte 167.801
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 167.801
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.116 0 386 163 436 224 99 169 155 159 320 353 652
2022/20234.797 305 481 618 660 470 945 91 373 469 129 161 95
2023/20244.156 141 70 385 192 161 1.007 1.255 409 20 99 93 324
2024/20256.970 171 401 609 389 898 565 199 442 471 283 707 1.835
2025/202618.032 1.373 3.696 1.954 1.812 3.128 489 1.923 428 599 793 387 1.450
2026/20271.172 739 433 0 0 0 0 0 0 0 0 0 0
Totale 56.278