IRIS
BALDARI, COSIMA
 Distribuzione geografica
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Continente #
NA - Nord America 23.197
EU - Europa 17.523
AS - Asia 9.314
SA - Sud America 1.435
AF - Africa 441
OC - Oceania 33
Continente sconosciuto - Info sul continente non disponibili 25
Totale 51.968
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Nazione #
US - Stati Uniti d'America 22.915
GB - Regno Unito 4.356
CN - Cina 3.285
RU - Federazione Russa 3.169
SG - Singapore 2.842
IE - Irlanda 2.283
IT - Italia 2.217
SE - Svezia 1.327
BR - Brasile 1.199
UA - Ucraina 1.133
VN - Vietnam 963
FR - Francia 940
DE - Germania 867
HK - Hong Kong 724
FI - Finlandia 574
KR - Corea 505
IN - India 241
ZA - Sudafrica 175
CA - Canada 136
ES - Italia 122
BD - Bangladesh 120
NL - Olanda 116
AR - Argentina 86
IQ - Iraq 81
TR - Turchia 79
NG - Nigeria 78
BE - Belgio 74
MX - Messico 73
JP - Giappone 70
CI - Costa d'Avorio 66
AT - Austria 53
CH - Svizzera 50
PL - Polonia 47
CZ - Repubblica Ceca 45
SA - Arabia Saudita 44
ID - Indonesia 42
PK - Pakistan 41
IR - Iran 38
VE - Venezuela 33
EC - Ecuador 32
UZ - Uzbekistan 30
KE - Kenya 29
CO - Colombia 26
EU - Europa 25
IL - Israele 25
AU - Australia 24
LT - Lituania 24
AE - Emirati Arabi Uniti 23
MA - Marocco 21
GR - Grecia 20
JO - Giordania 19
PA - Panama 18
TN - Tunisia 18
EG - Egitto 17
MY - Malesia 16
PH - Filippine 16
CL - Cile 15
DZ - Algeria 14
PE - Perù 13
KG - Kirghizistan 12
UY - Uruguay 12
AZ - Azerbaigian 11
KZ - Kazakistan 11
PT - Portogallo 11
PY - Paraguay 11
JM - Giamaica 10
NP - Nepal 10
CR - Costa Rica 9
DO - Repubblica Dominicana 9
DK - Danimarca 8
GE - Georgia 8
HN - Honduras 8
SK - Slovacchia (Repubblica Slovacca) 8
HU - Ungheria 7
NZ - Nuova Zelanda 7
RO - Romania 7
AL - Albania 6
BY - Bielorussia 6
ET - Etiopia 6
LK - Sri Lanka 6
LU - Lussemburgo 6
NI - Nicaragua 6
OM - Oman 6
BO - Bolivia 5
LB - Libano 5
NO - Norvegia 5
RS - Serbia 5
TT - Trinidad e Tobago 5
AM - Armenia 4
BA - Bosnia-Erzegovina 4
BH - Bahrain 4
GA - Gabon 4
HR - Croazia 4
LA - Repubblica Popolare Democratica del Laos 4
LV - Lettonia 4
MK - Macedonia 4
TH - Thailandia 4
AO - Angola 3
CY - Cipro 3
EE - Estonia 3
Totale 51.905
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Città #
Southend 3.865
Dallas 3.629
Dublin 2.253
Fairfield 1.983
Ashburn 1.739
Singapore 1.730
Menlo Park 1.598
Chandler 1.205
Santa Clara 977
Woodbridge 953
Jacksonville 928
Moscow 859
San Jose 846
Wilmington 822
Seattle 795
Beijing 749
Houston 717
Hong Kong 693
Cambridge 669
Ann Arbor 656
Hefei 644
Siena 591
Seoul 494
Princeton 376
The Dalles 347
Nanjing 318
Helsinki 305
Los Angeles 301
Ho Chi Minh City 271
New York 238
Florence 236
Lauterbourg 232
Council Bluffs 209
Hanoi 191
Dong Ket 176
Milan 176
Venezia 168
Dearborn 156
Johannesburg 149
Munich 148
Boardman 139
Shanghai 133
Buffalo 131
San Diego 122
São Paulo 108
San Mateo 106
Rome 94
Nanchang 92
Shenyang 91
London 89
Bengaluru 88
Fremont 80
Orem 78
Columbus 77
Abuja 75
Málaga 75
Lancaster 68
Abidjan 66
Brussels 65
Frankfurt am Main 62
Kunming 60
Lappeenranta 59
Tianjin 54
San Francisco 53
Tokyo 50
Chennai 48
Düsseldorf 47
Rio de Janeiro 47
Haiphong 46
Hebei 46
Phoenix 46
Amsterdam 45
Jinan 45
Redondo Beach 44
Changsha 43
Chicago 43
Nuremberg 41
Turku 41
Warsaw 40
Guangzhou 38
Norwalk 38
Toronto 37
Belo Horizonte 36
Jiaxing 36
Montreal 36
Zhengzhou 35
Redwood City 34
Brno 33
Washington 33
Vienna 32
Brasília 31
Da Nang 30
Atlanta 29
Brooklyn 29
Denver 29
Tashkent 29
Dhaka 28
Izmir 27
Ningbo 27
Baghdad 25
Totale 36.801
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Nome #
Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles 1.178
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T cell antigen receptor signaling to Ras family GTPases and Myc dependent survival 635
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape 390
Development of novel cyclic peptides as pro-apoptotic agents 388
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 367
A T cell suppressive circuitry mediated by CD39 and regulated by ShcC/RAI is induced in astrocytes by encephalitogenic T cells 357
Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment 347
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 335
Phase Ib study of poly-epitope peptide vaccination to thymidylate synthase (TSPP) and GOLFIG chemo-immunotherapy for treatment of metastatic colorectal cancer patients 335
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis 334
Analysis of TCR/CD3 recycling at the immune synapse 333
The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases 333
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system 333
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly 331
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 311
Anthrax toxins suppress T-lymphocyte activation by disrupting antigen receptor signaling. 305
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes 305
Compartmentalized cyclic AMP production by the Bordetella pertussis and Bacillus anthracis adenylate cyclase toxins differentially affects the immune synapse in T lymphocytes 304
A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly 303
Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells 302
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 302
The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis 299
Colchicine myopathy and neuromyopathy: two cases with different characteristics 297
The T cell IFT20 interactome reveals new players in immune synapse assembly 293
The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse 293
Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia 292
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia 291
An apical actin-rich domain drives the establishment of cell polarity during cell adhesion. 290
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia 288
The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells 285
Validation of a diagnostic score for the diagnosis of autoinflammatory diseases in adults 284
The Shc protein Rai enhances T-cell survival under hypoxia 279
Altered balance of helper T cells in Rai-/- mice 278
Intraflagellar transport: a new player at the immune synapse. 275
F-actin dynamics controls segregation of the TCR signaling cascade to clustered lipid rafts 272
Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway 272
A Ciliary View of the Immunological Synapse 272
An intraflagellar transport component is required for polarized recycling of the TCR/CD3 complex to the immune synapse 270
Astrocyte deficiency of the Shc family member Rai attenuates myelin-reactive Th17 cell-dependent neurodegeneration in EAE: a mechanistic study of astrocyte-T cell interactions 269
The Rab GTPase Rab8 as a shared regulator of ciliogenesis and immune synapse assembly: from a conserved pathway to diverse cellular structures 267
p66Shc promotes T-cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis 266
Dysfunctional immune synapses in T cell immunodeficiencies 264
IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo 263
p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics 263
Human cytotoxic T lymphocytes form dysfunctional immune synapses with B cells characterized by non-polarized lytic granule release 263
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) 261
Lack of p66Shc in the CLL mouse model E mu-TCL1 exacerbates nodal and extranodal infiltration of leukemic cells which can undergo Richter's transformation 255
An AMBRA1, ULK1 and PP2A regulatory network regulates cytotoxic T cell differentiation via TFEB activation 254
The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of Th17 cell development 252
Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells 252
Anthrax toxins: a paradigm of bacterial immune suppression 251
Anthrax toxins inhibit immune cell chemotaxis 250
The adaptor protein p66shc is a positive regulator in the angiogenic response induced by hypoxic T cells 249
Altered balance of helper T cells in Rai-/- mice 249
The immune synapse: Past, present, and future 249
The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity 245
T cell costimulation by the hepatitis C virus envelope protein E2 binding to CD81 is mediated by Lck 244
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T-cells 243
Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters 242
Intrinsic factor recognition promotes T helper 17/T helper 1 autoimmune gastric inflammation in patients with pernicious anemia 242
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 241
Src family kinases regulate interferon regulatory factor 1 K63 ubiquitination following activation by TLR7/8 vaccine adjuvant in human monocytes and B cells 240
The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II 240
Hypoxia and immune surveillance: role of the adaptor protein p66ShcA in negative regulation of T-cell activation and survival ' 239
Antigen receptor signaling under the tuscan sun 238
Simvastatin inhibits T cell activation by selectively impairing the function of RAS superfamily GTPases 238
The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development 238
Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia 238
B cell development: COX-1 joins the game 236
Transcellular communication at the immunological synapse: A vesicular traffic-mediated mutual exchange 235
Regulation of T Cell Activation and Differentiation by Extracellular Vesicles and Their Pathogenic Role in Systemic Lupus Erythematosus and Multiple Sclerosis 235
Vesicular trafficking to the immune synapse: How to assemble receptor-tailored pathways from a basic building set 233
First report of circulating microRNAs in tumour necrosis factor receptor-associated periodic syndrome (TRAPS). 232
The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation. 232
Boosting chemokine receptor recycling: An elixir of life for chronic lymphocytic leukemia 231
Astrocytic ShcC/Rai supports the function of autoreactive T cells during EAE by modulating adenosine-dependent CTLA4 expression through the inhibition of CD39 and CD73 activity 231
ZAP-70. AfCS-Nature Molecule Pages 228
Regulation of vesicular traffic at the T cell immune synapse: lessons from the primary cilium 227
Signals controlling lytic granule polarization at the cytotoxic immune synapse 227
Statins and the joint: multiple targets for a global protection? 227
Anthax toxins: a weapon to systematically dismantle the host immune defenses. 226
Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium 226
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays 225
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis 224
Neisseria meningitidis subverts the polarized organization and intracellular trafficking of host cells to cross the epithelial barrier 223
Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis 222
Nonsteroidal anti-inflammatory drugs inhibit a Fyn dependent pathway coupled to Rac and stress kinase activation in TCR signaling 221
The B-side of the immune response 219
p66Shc: the apoptotic side of Shc proteins 218
The CXCL12/CXCR4 Axis as a Therapeutic Target in Cancer and HIV-1 Infection 218
Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse 218
Regulation of Selective B Cell Autophagy by the Pro-oxidant Adaptor p66SHC 218
The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells 217
The possible role of T cells and neutrophils in the regulation of tumour angiogenesis 216
Development and preliminary validation of a diagnostic score for identifying patients affected with adult-onset autoinflammatory disorders 215
Systemic-onset juvenile idiopathic arthritis complicated by early onset amyloidosis in a patient carrying a mutation in the MEFV gene 214
Defective Vav expression and impaired F-actin reorganization in a subset of common variable immunodeficiency patients with T-cell defects 214
Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus 213
Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering 213
Expression in T-cells of the proapoptotic protein p66SHC is controlled by promoter demethylation. 212
Totale 27.609
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Categoria #
all - tutte 156.418
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 156.418
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021382 0 0 0 0 0 0 0 0 0 0 0 382
2021/20223.284 233 377 161 425 223 98 168 153 158 310 345 633
2022/20234.650 296 468 598 642 453 913 89 358 457 125 158 93
2023/20244.053 135 67 377 184 158 975 1.221 408 20 97 93 318
2024/20256.741 166 387 589 380 876 536 196 435 446 277 676 1.777
2025/202616.399 1.345 3.628 1.910 1.767 3.025 471 1.835 420 584 763 375 276
Totale 52.569