Nome |
# |
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis., file e0feeaa4-f2b2-44d2-e053-6605fe0a8db0
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187
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Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system, file e0feeaa5-0abe-44d2-e053-6605fe0a8db0
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179
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p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape, file e0feeaa8-3781-44d2-e053-6605fe0a8db0
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174
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Orchestration of Immunological Synapse Assembly by Vesicular Trafficking, file e0feeaa8-37f2-44d2-e053-6605fe0a8db0
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172
|
Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse, file e0feeaa8-345e-44d2-e053-6605fe0a8db0
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167
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Src family kinases regulate interferon regulatory factor 1 K63 ubiquitination following activation by TLR7/8 vaccine adjuvant in human monocytes and B cells, file e0feeaa7-dca9-44d2-e053-6605fe0a8db0
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163
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Intrinsic factor recognition promotes T helper 17/T helper 1 autoimmune gastric inflammation in patients with pernicious anemia, file e0feeaa8-2e9f-44d2-e053-6605fe0a8db0
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142
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A T cell suppressive circuitry mediated by CD39 and regulated by ShcC/RAI is induced in astrocytes by encephalitogenic T cells, file e0feeaa8-1c04-44d2-e053-6605fe0a8db0
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136
|
Human cytotoxic T lymphocytes form dysfunctional immune synapses with B cells characterized by non-polarized lytic granule release, file e0feeaa5-c7eb-44d2-e053-6605fe0a8db0
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133
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The T cell IFT20 interactome reveals new players in immune synapse assembly, file e0feeaa6-2251-44d2-e053-6605fe0a8db0
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132
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Signals controlling lytic granule polarization at the cytotoxic immune synapse, file e0feeaa7-db46-44d2-e053-6605fe0a8db0
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128
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p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB, file 8c4550d7-b86f-43d2-b9ee-b0574cf7b66d
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125
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LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy, file e0feeaa8-2e9e-44d2-e053-6605fe0a8db0
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123
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An apical actin-rich domain drives the establishment of cell polarity during cell adhesion., file e0feeaa4-ec7e-44d2-e053-6605fe0a8db0
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121
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Compartmentalized cyclic AMP production by the Bordetella pertussis and Bacillus anthracis adenylate cyclase toxins differentially affects the immune synapse in T lymphocytes, file e0feeaa7-d70a-44d2-e053-6605fe0a8db0
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118
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Boosting chemokine receptor recycling: An elixir of life for chronic lymphocytic leukemia, file e0feeaa7-d70d-44d2-e053-6605fe0a8db0
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117
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Interleukin-17/Interleukin-21 and Interferon-g producing T cells specific for β2 Glycoprotein I in atherosclerosis inflammation of systemic lupus erythematosus patients with antiphospholipid syndrome, file e0feeaa8-3edd-44d2-e053-6605fe0a8db0
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113
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A Ciliary View of the Immunological Synapse, file e0feeaa8-403a-44d2-e053-6605fe0a8db0
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112
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Transcellular communication at the immunological synapse: A vesicular traffic-mediated mutual exchange, file e0feeaa7-d70c-44d2-e053-6605fe0a8db0
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111
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Nature vs. Nurture: The Two Opposing Behaviors of Cytotoxic T Lymphocytes in the Tumor Microenvironment, file e0feeaaa-d116-44d2-e053-6605fe0a8db0
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81
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Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway, file e0feeaa6-254b-44d2-e053-6605fe0a8db0
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72
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Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays, file e0feeaa8-eb00-44d2-e053-6605fe0a8db0
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72
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The Intraflagellar Transport Protein IFT20 Recruits ATG16L1 to Early Endosomes to Promote Autophagosome Formation in T Cells, file e0feeaaa-bc6b-44d2-e053-6605fe0a8db0
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69
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Emerging Roles of the Intraflagellar Transport System in the Orchestration of Cellular Degradation Pathways, file e0feeaa8-d075-44d2-e053-6605fe0a8db0
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66
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Differential proteomic analysis of astrocytes and astrocytes-derived extracellular vesicles from control and rai knockout mice: insights into the mechanisms of neuroprotection, file e0feeaaa-cd39-44d2-e053-6605fe0a8db0
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66
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Learning from TCR Signaling and Immunological Synapse Assembly to Build New Chimeric Antigen Receptors (CARs)., file a93a4b51-5400-4b6a-a45f-66f6537d8222
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65
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Regulation of Selective B Cell Autophagy by the Pro-oxidant Adaptor p66SHC, file e0feeaa9-05b9-44d2-e053-6605fe0a8db0
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64
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SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly, file c7480c5b-74c7-4cd3-a53c-0c4db9d2c455
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62
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F-Actin Dynamics in the Regulation of Endosomal Recycling and Immune Synapse Assembly, file e0feeaaa-9e2d-44d2-e053-6605fe0a8db0
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62
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Vesicular trafficking to the immune synapse: How to assemble receptor-tailored pathways from a basic building set, file e0feeaa6-20ea-44d2-e053-6605fe0a8db0
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58
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Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells, file e0feeaa6-29aa-44d2-e053-6605fe0a8db0
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57
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The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells, file e0feeaa6-2a16-44d2-e053-6605fe0a8db0
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52
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Defective signaling to Fyn by a TCR lacking the a-chain connecting peptide motif, file e0feeaaa-5e4f-44d2-e053-6605fe0a8db0
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50
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The Adenylate Cyclase Toxins of Bacillus anthracis and Bordetella pertussis Promote Th2 Cell Development by Shaping T Cell Antigen Receptor Signaling, file e0feeaa4-c924-44d2-e053-6605fe0a8db0
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48
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Increasing LFA-1 Expression Enhances Immune Synapse Architecture and T Cell Receptor Signaling in Jurkat E6.1 Cells, file e0feeaaa-9e9f-44d2-e053-6605fe0a8db0
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48
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Lymphocyte Polarization During Immune Synapse Assembly: Centrosomal Actin Joins the Game, file e32c58f7-362b-4954-9c8c-d88bc49ff6d2
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44
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P66shc: A pleiotropic regulator of B cell trafficking and a gatekeeper in chronic lymphocytic leukemia, file e0feeaab-3f23-44d2-e053-6605fe0a8db0
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42
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Regulation of T Cell Activation and Differentiation by Extracellular Vesicles and Their Pathogenic Role in Systemic Lupus Erythematosus and Multiple Sclerosis, file e0feeaa6-1e07-44d2-e053-6605fe0a8db0
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39
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Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1, file e0feeaa9-dc9e-44d2-e053-6605fe0a8db0
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35
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Development of novel cyclic peptides as pro-apoptotic agents, file e0feeaab-defe-44d2-e053-6605fe0a8db0
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35
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The Expanding Arsenal of Cytotoxic T Cells, file fa3293d7-c716-478f-898f-79365b6e5d78
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32
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Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation, file 4283228b-2437-421e-b40f-6af1d698a31d
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31
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Interleukin (IL)-9 Supports the Tumor-Promoting Environment of Chronic Lymphocytic Leukemia, file 5827f762-8f8e-4919-b373-cb46a1f3b240
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30
|
A T cell suppressive circuitry mediated by CD39 and regulated by ShcC/RAI is induced in astrocytes by encephalitogenic T cells, file e0feeaa8-3eed-44d2-e053-6605fe0a8db0
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25
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T-cell-based immunotherapy of autoimmune diseases, file e0feeaa5-982c-44d2-e053-6605fe0a8db0
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21
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Rai promotes astrocyte-dependent inflammation during experimental autoimmune encephalomyelitis, file e0feeaa8-3edf-44d2-e053-6605fe0a8db0
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21
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Intraflagellar transport: a new player at the immune synapse., file e0feeaaa-53ea-44d2-e053-6605fe0a8db0
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20
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The immunological synapse: an emerging target for immune evasion by bacterial pathogens, file f52cd595-63c7-46e9-bfcc-9e408d5f1352
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19
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Interleukin-17/Interleukin-21 and Interferon-g producing T cells specific for β2 Glycoprotein I in atherosclerosis inflammation of systemic lupus erythematosus patients with antiphospholipid syndrome, file e0feeaa8-47c7-44d2-e053-6605fe0a8db0
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16
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IFT20: An Eclectic Regulator of Cellular Processes beyond Intraflagellar Transport, file b5ad3436-1861-41af-8b4f-969b242c0b33
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15
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Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes, file d4b4c021-d0b0-4393-98cc-bfc9068e1a67
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15
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Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents, file e0feeaaa-4452-44d2-e053-6605fe0a8db0
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15
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p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes, file e0feeaab-62a8-44d2-e053-6605fe0a8db0
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13
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The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II, file e0feeaa7-d70f-44d2-e053-6605fe0a8db0
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12
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Treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway (vol 6, 2018), file 4ef6457a-51ba-4f0a-bc00-64dc16f94bce
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11
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Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia, file e0feeaa9-9d01-44d2-e053-6605fe0a8db0
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7
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The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse, file e0feeaa9-b046-44d2-e053-6605fe0a8db0
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7
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Phase Ib study of poly-epitope peptide vaccination to thymidylate synthase (TSPP) and GOLFIG chemo-immunotherapy for treatment of metastatic colorectal cancer patients, file e0feeaa9-b948-44d2-e053-6605fe0a8db0
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7
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The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis, file e0feeaa9-c21d-44d2-e053-6605fe0a8db0
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7
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IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo, file e0feeaa9-c220-44d2-e053-6605fe0a8db0
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7
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Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression, file 41046031-c304-4323-8cfa-bdacc4682f6f
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6
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p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes, file e0feeaa8-010c-44d2-e053-6605fe0a8db0
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6
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Identification and characterization of a novel NFAT1 isoform expressed in mouse brain, file e0feeaa5-af76-44d2-e053-6605fe0a8db0
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5
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Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia, file 466a3ed6-bddd-4f52-8dab-18d8b91c5b92
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4
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Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents, file e0feeaa7-bb57-44d2-e053-6605fe0a8db0
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4
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Ligation of human Fc receptor like-2 (FCRL2) by monoclonal antibodies downregulates B cell receptor mediated signaling., file e0feeaa5-94a0-44d2-e053-6605fe0a8db0
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3
|
The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development, file e0feeaa5-95b2-44d2-e053-6605fe0a8db0
|
3
|
p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics, file e0feeaa5-98d6-44d2-e053-6605fe0a8db0
|
3
|
Phosphoproteomic analysis of CD2 signaling reveals an AMPK-dependent targeted granule secretion in human cytotoxic T cells, file e0feeaa9-840f-44d2-e053-6605fe0a8db0
|
3
|
Role of etanercept in the treatment of tumor necrosis factor receptor-associated periodic syndrome: personal experience and review of the literature, file e0feeaa5-7dcb-44d2-e053-6605fe0a8db0
|
2
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Development and preliminary validation of a diagnostic score for identifying patients affected with adult-onset autoinflammatory disorders, file e0feeaa5-e4a7-44d2-e053-6605fe0a8db0
|
2
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Analysis of TCR/CD3 recycling at the immune synapse, file e0feeaa6-2a55-44d2-e053-6605fe0a8db0
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2
|
Saturday night fever: bizarre recurrence of fever attacks in a patient carrying a mutation in both the MEFV and TNFRSF1A genes, file e0feeaa7-903b-44d2-e053-6605fe0a8db0
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2
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Themis releases the brakes on TCR signaling during thymocyte selection by disabling SHP-1, file e0feeaa7-d70b-44d2-e053-6605fe0a8db0
|
2
|
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia, file e0feeaa8-314c-44d2-e053-6605fe0a8db0
|
2
|
The Shc protein Rai enhances T-cell survival under hypoxia, file e0feeaa9-5630-44d2-e053-6605fe0a8db0
|
2
|
Development of novel cyclic peptides as pro-apoptotic agents, file e0feeaa9-e7ed-44d2-e053-6605fe0a8db0
|
2
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cAMP: a multifaceted modulator of immune synapse assembly and T cell activation, file 06a62f79-7b75-4001-8aaf-950e84445add
|
1
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Sequence of two cDNA clones from the medfly Ceratitis capitata encoding antibacterial peptides of the cecropin family, file e0feeaa4-c598-44d2-e053-6605fe0a8db0
|
1
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Generation of a monoclonal antibody to a defined portion of the Helicobacter pylori vacuolating cytotoxin by DNA immunization, file e0feeaa4-cd55-44d2-e053-6605fe0a8db0
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1
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Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases., file e0feeaa4-da8d-44d2-e053-6605fe0a8db0
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1
|
p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells, file e0feeaa4-daf3-44d2-e053-6605fe0a8db0
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1
|
Restoration of thymic development in an Lck-/- thymoma overexpressing ZAP-70, file e0feeaa4-dec2-44d2-e053-6605fe0a8db0
|
1
|
Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus, file e0feeaa4-e057-44d2-e053-6605fe0a8db0
|
1
|
p66Shc promotes apoptosis and antagonises mitogenic signaling in T cells., file e0feeaa4-e070-44d2-e053-6605fe0a8db0
|
1
|
The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation., file e0feeaa4-e981-44d2-e053-6605fe0a8db0
|
1
|
First report of circulating microRNAs in tumour necrosis factor receptor-associated periodic syndrome (TRAPS)., file e0feeaa4-fd30-44d2-e053-6605fe0a8db0
|
1
|
Cytokine BAFF Released by Helicobacter pylori-Infected Macrophages Triggers the Th17 Response in Human Chronic Gastritis, file e0feeaa5-76a9-44d2-e053-6605fe0a8db0
|
1
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Cytokine BAFF Released by Helicobacter pylori-Infected Macrophages Triggers the Th17 Response in Human Chronic Gastritis, file e0feeaa5-7bb0-44d2-e053-6605fe0a8db0
|
1
|
Defective recruitment and activation of ZAP-70 in CVID patients with T-cell defects., file e0feeaa5-94a2-44d2-e053-6605fe0a8db0
|
1
|
Statins: From cholesterol-lowering drugs to novel immunomodulators for the treatment of Th17-mediated autoimmune diseases, file e0feeaa5-96f6-44d2-e053-6605fe0a8db0
|
1
|
The immune synapse: Past, present, and future, file e0feeaa6-2641-44d2-e053-6605fe0a8db0
|
1
|
S1PR2 deficiency in DLBCL: A FOXy connection, file e0feeaa6-2b88-44d2-e053-6605fe0a8db0
|
1
|
p66Shc promotes T-cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis, file e0feeaa6-df48-44d2-e053-6605fe0a8db0
|
1
|
Molecular mechanisms underlying suppression of lymphocyte responses by nonsteroidal antiinflammatory drugs, file e0feeaa7-92d4-44d2-e053-6605fe0a8db0
|
1
|
p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells, file e0feeaa7-9735-44d2-e053-6605fe0a8db0
|
1
|
The immunological synapse as a pharmacological target, file e0feeaa7-db45-44d2-e053-6605fe0a8db0
|
1
|
Gene activating and proapoptotic potential are independent properties of different CD4 epitopes, file e0feeaa7-edfd-44d2-e053-6605fe0a8db0
|
1
|
The lipoprotein HP1454 of Helicobacter pylori regulates T-cell response by shaping T-cell receptor signalling, file e0feeaa8-0608-44d2-e053-6605fe0a8db0
|
1
|
About creation and other misnomers, file e0feeaa9-4ebd-44d2-e053-6605fe0a8db0
|
1
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Totale |
4.247 |