IRIS
MUGNAINI, CLAUDIA
 Distribuzione geografica
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Continente #
NA - Nord America 8.036
EU - Europa 6.187
AS - Asia 3.478
SA - Sud America 630
Continente sconosciuto - Info sul continente non disponibili 179
AF - Africa 167
OC - Oceania 10
Totale 18.687
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Nazione #
US - Stati Uniti d'America 7.900
IT - Italia 1.324
GB - Regno Unito 1.228
CN - Cina 1.085
RU - Federazione Russa 1.057
SG - Singapore 1.044
IE - Irlanda 745
BR - Brasile 507
FR - Francia 388
SE - Svezia 384
UA - Ucraina 374
VN - Vietnam 335
DE - Germania 284
HK - Hong Kong 281
KR - Corea 196
FI - Finlandia 175
IN - India 120
BD - Bangladesh 111
TR - Turchia 83
ZA - Sudafrica 73
CA - Canada 51
MX - Messico 50
AR - Argentina 49
JP - Giappone 39
ES - Italia 38
NL - Olanda 29
PL - Polonia 29
CI - Costa d'Avorio 23
IQ - Iraq 21
CO - Colombia 19
NG - Nigeria 19
PK - Pakistan 19
AT - Austria 16
BE - Belgio 16
SA - Arabia Saudita 16
CZ - Repubblica Ceca 15
ID - Indonesia 15
EC - Ecuador 14
TW - Taiwan 13
EG - Egitto 11
RO - Romania 11
AE - Emirati Arabi Uniti 10
AU - Australia 10
LT - Lituania 10
CH - Svizzera 9
JO - Giordania 9
MY - Malesia 9
PY - Paraguay 9
AL - Albania 8
CL - Cile 8
PT - Portogallo 8
KE - Kenya 7
MA - Marocco 7
NP - Nepal 7
TN - Tunisia 7
UY - Uruguay 7
UZ - Uzbekistan 7
VE - Venezuela 7
BG - Bulgaria 6
DZ - Algeria 6
PE - Perù 6
RS - Serbia 6
CR - Costa Rica 5
GR - Grecia 5
HN - Honduras 5
IL - Israele 5
IR - Iran 5
JM - Giamaica 5
KZ - Kazakistan 5
LB - Libano 5
PH - Filippine 5
AM - Armenia 4
DO - Repubblica Dominicana 4
ET - Etiopia 4
GE - Georgia 4
LV - Lettonia 4
NI - Nicaragua 4
SN - Senegal 4
SV - El Salvador 4
KW - Kuwait 3
LK - Sri Lanka 3
MD - Moldavia 3
OM - Oman 3
PS - Palestinian Territory 3
SK - Slovacchia (Repubblica Slovacca) 3
AZ - Azerbaigian 2
BF - Burkina Faso 2
BH - Bahrain 2
BO - Bolivia 2
EE - Estonia 2
GT - Guatemala 2
HR - Croazia 2
HU - Ungheria 2
LY - Libia 2
MM - Myanmar 2
PA - Panama 2
SI - Slovenia 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
AO - Angola 1
Totale 18.494
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Città #
Southend 1.074
Dallas 997
Dublin 744
Fairfield 743
Singapore 592
Ashburn 559
Menlo Park 426
Santa Clara 368
Woodbridge 365
San Jose 339
Chandler 319
Jacksonville 299
Wilmington 294
Beijing 292
Houston 285
Moscow 281
Seattle 281
Milan 278
Cambridge 269
Hong Kong 269
Siena 261
Hefei 213
Seoul 190
Ann Arbor 169
Council Bluffs 169
The Dalles 151
Princeton 124
Los Angeles 120
Ho Chi Minh City 119
Rome 113
Florence 93
Helsinki 93
Nanjing 90
New York 83
Hanoi 76
Lauterbourg 75
Johannesburg 66
Boardman 62
Izmir 57
Fremont 54
Buffalo 51
Columbus 49
São Paulo 48
San Diego 42
San Mateo 42
Munich 40
Nanchang 36
Bengaluru 33
Dearborn 33
Shanghai 33
London 30
Frankfurt am Main 29
Tokyo 29
Shenyang 28
Chicago 27
Abidjan 23
Tianjin 23
Turku 22
Chennai 21
Orem 20
Rio de Janeiro 19
San Francisco 19
Haiphong 18
Abuja 17
Bologna 17
Düsseldorf 17
Mumbai 17
Naples 17
Anguillara Sabazia 16
Phoenix 16
Redondo Beach 16
Turin 16
Hebei 15
Atlanta 14
Brooklyn 14
Brussels 14
Guangzhou 14
Mexico City 14
Montreal 14
Cardiff 13
Jiaxing 13
Jinan 13
Vienna 13
Bari 12
Boston 12
Paris 12
Redwood City 12
Warsaw 12
Belo Horizonte 11
Brno 11
Changsha 11
Da Nang 11
Figino 11
Kunming 11
Norwalk 11
Zhengzhou 11
Guarulhos 10
L’Aquila 10
Málaga 10
Amsterdam 9
Totale 12.654
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Nome #
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: preliminary in vitro studies with analogues of immucillin-G 378
Synthesis of pyrazolo[1,5-a]pyrimidine ring as a possible bioisosteric replacement of the 5-(1H-pyrrol-1-yl)pyrazole scaffold 366
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor 336
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 334
Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease 317
Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach 315
New fluoroquinolones active against fluoroquinolones-resistant Mycobacterium tuberculosis strains 288
Design, Synthesis, and Pharmacological Characterization of Indole-3-ylacetamides, Indole-3-yloxoacetamides, and Indole-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse Agonists 287
Activation of the GABAB receptor prevents nicotine-induced locomotor stimulation in mice 285
Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors 282
Development and characterization of immobilized cannabinoid receptor (CB1/CB2) open tubular column for on-line screening 277
Synthesis, 1 structural properties, and pharmacological evaluation of 2-(acylamino)thiophene-3-carboxamides and analogues thereof 267
Screen of unfocused libraries identified compounds with direct or synergistic antibacterial activity 262
A combinatorial approach for the solid phase synthesis of 5,6-disubstituted pyrimidinones and pyrimidine derivatives 260
A new linker for anchoring/masking primary amines on solid support 260
Dihydro-alkylthio-benzyl-oxopyrimidines as Inhibitors of Reverse Transcriptase: Synthesis and Rationalization of the Biological Data on Both Wild-Type Enzyme and Relevant Clinical Mutants 258
An improved synthesis of solid-supported reagents (SSRs) for selective acylation of amines by microwave irradiation 258
Suppressing effect of COR659 on alcohol, sucrose, and chocolate self-administration in rats: Involvement of the GABAB and cannabinoid CB1 receptors 258
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility 256
Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor 255
NUOVA TERAPIA PER IL TRATTAMENTO DELL'IPERURICEMIA NELLA SINDROME DI LESCH-NYHAN 253
Anxiety-like behaviors at the end of the nocturnal period in sP rats with a “history” of unpredictable, limited access to alcohol. 252
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 3. Synthesis, Structure-Affinity Relationships, and Pharmacological Characterization of 6-Substituted 4-Quinolone-3-carboxamides as Highly Selective Cannabinoid-2 Receptor Ligands 251
Chiral Azole Derivatives, 3. Synthesis of the Enantiomers of the Potent Aromatase Inhibitor 1-[2-Benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole 247
Design, synthesis, and physicochemical and pharmacological profiling of 7‐Hydroxy-5-oxopyrazolo[4,3‐b]pyridine-6-carboxamide derivatives with antiosteoarthritic activity in vivo 247
Combinatorial chemistry as a tool for targeting different stages of the replicative HIV-1 cycle 245
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 1. Synthesis and Structure-Activity Relationship of a Class of Human Immunodeficiency Virus type 1 Integrase Inhibitors 245
Simplified Analogues of Immucillin-G Retain Potent Human Purine Nucleoside Phosphorylase Inhibitory Activity 244
Regioselective functionalization of quinolin-4(1H)-ones via sequential palladium-catalyzed reactions 244
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 240
A novel highly selective cannabinoid CB2 agonist reduces in vitro growth and TGF-beta release of human glial cell tumors 239
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 234
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 6. Synthesis and Pharmacological Evaluation of 7-Substituted 4-Quinolone-3-carboxamide Derivatives as High Affinity Ligands for Cannabinoid Receptors 234
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 2. Synthesis and Structure-Activity Relationship of Potent and Selective Cannabinoid-2 Receptor Agonists Endowed with Analgesic Activity in Vivo 233
Solid phase synthesis of 5,6-disubstituted pyrimidinone and pyrimidindione derivatives 232
Solution-phase parallel synthesis of S-DABO analogues 227
Reduction by the positive allosteric modulator of the GABAB receptor, GS39783, of alcohol self-administration in Sardinian alcohol-preferring rats exposed to the “sipper” procedure 223
Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies 222
The 4-Quinolone-3-carboxylic Acid Motif as a Multivalent Scaffold in Medicinal Chemistry 220
COR758, a negative allosteric modulator of GABAB receptors 220
Light-mediated activation/deactivation control and in vitro ADME-Tox profiling of a donepezil-like Dual AChE/MAO-B Inhibitor 215
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 215
Chiral Azole Derivatives. 4. Enantiomers of Bifonazole and Related Antifungal Agents: Stereoselective Synthesis, Configuration Assignment, and Biological Evaluation 213
Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands 212
Reducing effect of saikosaponin A, an active ingredient of Bupleurum falcatum, on alcohol self-administration in rats: Possible involvement of the GABAB receptor 211
Anti-addictive properties of COR659 – Additional pharmacological evidence and comparison with a series of novel analogues 211
Three-Dimensional Quantitative Structure-Selectivity Relationships (3D-QSSR) Analysis Guided Rational Design of a Highly Selective Ligand for the Cannabinoid Receptor 2 208
Comparison of the effect of the positive allosteric modulator of the GABAb receptor, GS39783, on alcohol self-administration in three different lines of alcohol-preferring rats 206
Rational design and synthesis of homochiral azole antifungal agents 205
Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors 204
Inhibition of alcohol self-administration by positive allosteric modulators of the GABA(B) receptor in rats: lack of tolerance and potentiation of baclofen 202
Practical synthesis of novel purine analogues as Hsp90 inhibitors. 200
Preparation of a set of 4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-4-ones as potential Hsp90 ligands 197
Synthesis and biological evaluation of guanidino compounds endowed with subnanomolar affinity as competitive inhibitors of maize polyamine oxidase 196
Towards new methodologies for the synthesis of biologically interesting 6-substituted pyrimidines and 4(3H)-pyrimidinones 191
Parallel Solution-Phase and Microwave-Assisted Synthesis of New S-DABO Derivatives Endowed with Subnanomolar Anti-HIV-1 Activity 189
Chemistry of GABAB receptor ligands: focus on agonists and antagonists 189
Synthesis of reactive cytidine derivatives as building blocks for cross-linking oligonucleotides 188
null 186
The bioisosteric concept applied to cannabinoid ligands 184
Synthesis and biological investigation of S-aryl-S-DABO derivatives as HIV-1 inhibitors 183
Optimization of Pyrazole Compounds as Antibiotic Adjuvants Active against Colistin- and Carbapenem-Resistant Acinetobacter baumannii 176
Microwave-assisted acylation of amines, alcohols and phenols by the use of solid-supported reagents (SSRs) 176
Total Synthesis of δ-Sanshool and Analogues Thereof 171
Lipoic/Capsaicin-Related Amides: Synthesis and Biological Characterization of New TRPV1 Agonists Endowed with Protective Properties against Oxidative Stress 170
USO DI DERIVATI DELL’ACIDO 2-AMMINOTIOFEN-3- CARBOSSILICO PER IL TRATTAMENTO DELLE DIPENDENZE DA CIBO 170
Synthesis and biological evaluation of thiophene-based cannabinoid receptor type 2 radiotracers for PET imaging 168
Suppressing effect of the novel positive allosteric modulator of the GABAB receptor, COR659, on locomotor hyperactivity induced by different drugs of abuse 164
Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo 163
Simplified Analogs Of Immucillin-G Retain Potent Human Purine Nucleoside Phosphorylase Inhibitory Activity 163
Synthesis and conformational studies of 3’-(2’-aminoborane-2’-deoxyuridyl)-5’-thymidilyl hydrogen phospate to be used in the construction of oligonucleotide sequences 159
Precise structure activity relationships in asymmetric catalysis using carbohydrate scaffolds to allow ready fine tuning: dialkylzinc-aldehyde additions 158
Synthesis and biological evaluation of 4-alkylamino-6-(2-hydroxyethyl)-2-methylthiopyrimidines as a new ribella virus inhibitors 157
Indole-2-Carboxamide as an Effective Scaffold for the Design of New TRPV1 Agonists 156
Research on L-Nucleosides. Synthesis and Biological Evaluation of a Series of L- and D-2’,3’-Dideoxy-3’-[Tris(methylthio)methyl]-β-Pentofuranosyl Nucleosides 155
New synthesis of N1- and N2-substituted pyrazolo[4,3-b]pyridine-5-one derivatives as CB2 receptor ligands 155
The allosteric modulation of the GABAB receptor: a medicinal chemistry perspective 152
Synthesis of some novel 1-aryl-1H-1,2,3-triazole-4-carboxamides and ethyl 1-aryl-5-(1,2,3-triazol-1-yl)-1H-pyrazole-4-carboxylates 151
Operant, oral alcohol self-administration: Sex differences in Sardinian alcohol-preferring rats 145
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor 140
In silico multi-target approach revealed potential lead compounds as scaffold for the synthesis of chemical analogues targeting SARS-CoV-2 128
The GABAB receptor positive allosteric modulator COR659: in vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives 128
Suppressing effect of CMPPE, a new positive allosteric modulator of the GABAB receptor, on alcohol self-administration and reinstatement of alcohol seeking in rats 126
Investigation on Novel E/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity 114
Potent immunomodulatory activity of a highly selective cannabinoid CB2 agonist on immune cells from healthy subjects and patients with multiple sclerosis. 114
Structure optimization of positive allosteric modulators of GABAB receptors led to the unexpected discovery of antagonists/potential negative allosteric modulators 110
The Selective CB2 Agonist COR167 Reduced Symptoms in a Mice Model of Trauma-Induced Peripheral Neuropathy through HDAC-1 Inhibition 106
Targeting TRPA1 with Novel Synthetic Compounds Based on Different Scaffolds to Reduce Acute and Chronic Pain 19
Light-Controlled Modulation of the Endocannabinoid System: Photoswitchable Ligands for Cannabinoid and TRPV1 Receptors 13
GABAB Receptor signaling in CA1 Pyramidal Cells is not Regulated by Aging in the APP/PS1 Mouse Model of Amyloid Pathology 12
A sesquiterpene-rich essential oil from Cannabis sativa L. attenuates symptoms and neuroinflammation in experimental autoimmune encephalomyelitis model through a CB2-mediated signalling 12
Totale 18.687
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Categoria #
all - tutte 57.495
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 57.495
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022807 0 0 78 104 29 42 57 39 39 119 90 210
2022/20231.398 97 94 205 171 136 297 44 121 128 34 52 19
2023/20241.256 71 24 83 101 50 268 418 35 11 19 28 148
2024/20252.459 56 134 237 141 279 136 94 149 240 123 230 640
2025/20266.079 478 1.150 618 633 1.000 218 642 190 198 273 191 488
2026/2027682 285 189 208 0 0 0 0 0 0 0 0 0
Totale 18.687