Starting from (+)- and (−)-1-(4-chlorophenyl)-2-propynylamine, in turn obtained by CAL-mediated kinetic resolution of the corresponding racemate, a stereoselective synthesis of both enantiomers of the title compound has been achieved.

Messina, F., Botta, M., Corelli, F., Mugnaini, C. (1999). Chiral Azole Derivatives, 3. Synthesis of the Enantiomers of the Potent Aromatase Inhibitor 1-[2-Benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole. TETRAHEDRON LETTERS, 40(40), 7289-7292 [10.1016/S0040-4039(99)01569-5].

Chiral Azole Derivatives, 3. Synthesis of the Enantiomers of the Potent Aromatase Inhibitor 1-[2-Benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole

Botta, Maurizio;Corelli, Federico;Mugnaini, Claudia
1999-01-01

Abstract

Starting from (+)- and (−)-1-(4-chlorophenyl)-2-propynylamine, in turn obtained by CAL-mediated kinetic resolution of the corresponding racemate, a stereoselective synthesis of both enantiomers of the title compound has been achieved.
1999
Messina, F., Botta, M., Corelli, F., Mugnaini, C. (1999). Chiral Azole Derivatives, 3. Synthesis of the Enantiomers of the Potent Aromatase Inhibitor 1-[2-Benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole. TETRAHEDRON LETTERS, 40(40), 7289-7292 [10.1016/S0040-4039(99)01569-5].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/11878
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