BOTTA, MAURIZIO
BOTTA, MAURIZIO
Dipartimento di Biotecnologie, Chimica e Farmacia
'Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells
2012-01-01 Colombo, F; Tintori, Cristina; Furlan, A; Borrelli, S; Christodoulou, Ms; Dono, R; Maina, F; Botta, Maurizio; Amat, M; Bosch, J; Passarella, D.
(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity
2020-01-01 Humbert, N; Kovalenko, L; Saladini, F; Giannini, A; Pires, M; Botzanowski, T; Cherenok, S; Boudier, C; Sharma, Kk; Real, E; Zaporozhets, Oa; Cianférani, S; Seguin-Devaux, C; Poggialini, F; Botta, M; Zazzi, M; Kalchenko, Vi; Mori, M; Mély, Y.
1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation
2009-01-01 Biava, M.; Porretta, G. C.; Poce, G.; De Logu, A.; Meleddu, R.; De Rossi, E.; Manetti, Fabrizio; Botta, Maurizio
1,5-Diarylpyrrole-3-acetic Acids and Esters as Novel Classes of Potent and Highly Selective Cyclooxygenase-2 Inhibitors
2005-01-01 Biava, M.; Porretta, G. C.; Cappelli, Andrea; Vomero, S.; Manetti, Fabrizio; Botta, Maurizio; Sautebin, L.; Rossi, A.; Makovec, F.; Anzini, Maurizio
1,5-Diphenylpyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings
2008-01-01 Biava, M; Porretta, G. C.; Poce, G; DE LOGU, A; Saddi, M; Meleddu, R; Manetti, Fabrizio; DE ROSSI, E; Botta, Maurizio
1-[(3-Aryloxy-3-aryl)propyl]-2H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies
2008-01-01 La Regina, G.; D'Auria, F.; Tafi, Andrea; Piscitelli, F.; Olla, S.; Caporuscio, F.; Nencioni, L.; Cirilli, R.; LA TORRE, F.; Rodrigues De Melo, N.; Kelly, S.; Lamb, D.; Artico, M.; Botta, Maurizio; Palamara, A.; Silvestri, R.
158. Preparation of analogues of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine as antitubercular agents
2006-01-01 Biava, Mariangela; Manetti, Fabrizio; Deidda, Delia; Pompei, Raffaello; Botta, Maurizio; Porretta, Giulio Cesare
2-Aminothiazolones as anti-hiv agents that act as gp120-cd4 inhibitors
2014-01-01 Tiberi, Marika; Tintori, Cristina; Ceresola, Elisa Rita; Fazi, Roberta; Zamperini, Claudio; Calandro, Pierpaolo; Franchi, Luigi; Selvaraj, Manikandan; Botta, Lorenzo; Sampaolo, Michela; Saita, Diego; Ferrarese, Roberto; Clementi, Massimo; Canducci, Filippo; Botta, Maurizio
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors
2010-01-01 Dreassi, Elena; Zizzari, ALESSANDRA TANIA; Mori, Mattia; Filippi, Irene; Belfiore, Amalia; Naldini, Antonella; Carraro, Fabio; Santucci, Annalisa; Schenone, Silvia; Botta, Maurizio
3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una nuova classe di ligandi potenti ed altamente selettivi per i recettori alfa1 adrenergici
2004-01-01 V., Pittala'; M. A., Siracusa; L., Salerno; F., Guerrera; G., Romeo; F., Russo; A., Cagnotto; T., Mennini; Manetti, Fabrizio; Botta, Maurizio
3-Arylidene-N-hydroxyoxindoles: A New Class of Compounds Endowed with Antitumor Activity
2016-01-01 Musso, Loana; Cincinelli, Raffaella; Zuco, Valentina; Decesare, Michelandrea; Zunino, Franco; Fallacara, ANNA LUCIA; Botta, Maurizio; Dallavalle, Sabrina
3D QSAR model on a set of selective A1 adenosine receptor (A1AR) antagonists
2004-01-01 Manetti, Fabrizio; Tintori, Cristina; A., Martinelli; M. L., Trincavelli; S., Schenone; Botta, Maurizio
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors
2008-01-01 Falchi, F.; Manetti, Fabrizio; Schenone, S.; Botta, Maurizio
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors
2009-01-01 Falchi, F.; Manetti, Fabrizio; Carraro, Fabio; Naldini, Antonella; Maga, G.; Crespan, E.; Schenone, S.; Bruno, O.; Brullo, C.; Botta, Maurizio
3D QSAR models of interaction between b-tubulin and MSAAs: taxanes and epothilones
2003-01-01 Maccari, L; Manetti, Fabrizio; Forli, S; Corelli, Federico; Botta, Maurizio
3D QSAR models of interactions between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA): a survey on taxanes and epothilones
2004-01-01 Manetti, Fabrizio; L., Maccari; Corelli, Federico; Botta, Maurizio
3D QSAR studies for the β-tubulin binding site of microtubule-stabilizing anticancer agents (MSAAs): A pseudoreceptor model for taxanes based on the experimental structure of tubulin
2003-01-01 Maccari, Laura; Manetti, Fabrizio; Corelli, Federico; Botta, Maurizio
3D QSAR studies of the interaction between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA). A combined pharmacophore generation and pseudoreceptor modeling approach applied to taxanes and epothilones
2003-01-01 Manetti, Fabrizio; Forli, Stefano; Maccari, Laura; Corelli, Federico; Botta, Maurizio
4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling
2016-01-01 Trist, Iuni M. L.; Nannetti, Giulio; Tintori, Cristina; Fallacara, ANNA LUCIA; Deodato, Davide; Mercorelli, Beatrice; Palù, Giorgio; Wijtmans, Maikel; Gospodova, Tzveta; Edink, Ewald; Verheij, Mark; De Esch, Iwan; Viteva, Lilia; Loregian, Arianna; Botta, Maurizio
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof
2004-01-01 Bondavalli, F; Botta, Maurizio; Manetti, Fabrizio; Donnini, Sandra; Schenone, S; Ziche, Marina
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 'Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells | 1-gen-2012 | Colombo, F; Tintori, Cristina; Furlan, A; Borrelli, S; Christodoulou, Ms; Dono, R; Maina, F; Botta, Maurizio; Amat, M; Bosch, J; Passarella, D. | - | |
| (Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity | 1-gen-2020 | Humbert, N; Kovalenko, L; Saladini, F; Giannini, A; Pires, M; Botzanowski, T; Cherenok, S; Boudier, C; Sharma, Kk; Real, E; Zaporozhets, Oa; Cianférani, S; Seguin-Devaux, C; Poggialini, F; Botta, M; Zazzi, M; Kalchenko, Vi; Mori, M; Mély, Y. | - | |
| 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation | 1-gen-2009 | Biava, M.; Porretta, G. C.; Poce, G.; De Logu, A.; Meleddu, R.; De Rossi, E.; Manetti, Fabrizio; Botta, Maurizio | - | |
| 1,5-Diarylpyrrole-3-acetic Acids and Esters as Novel Classes of Potent and Highly Selective Cyclooxygenase-2 Inhibitors | 1-gen-2005 | Biava, M.; Porretta, G. C.; Cappelli, Andrea; Vomero, S.; Manetti, Fabrizio; Botta, Maurizio; Sautebin, L.; Rossi, A.; Makovec, F.; Anzini, Maurizio | - | |
| 1,5-Diphenylpyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings | 1-gen-2008 | Biava, M; Porretta, G. C.; Poce, G; DE LOGU, A; Saddi, M; Meleddu, R; Manetti, Fabrizio; DE ROSSI, E; Botta, Maurizio | - | |
| 1-[(3-Aryloxy-3-aryl)propyl]-2H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies | 1-gen-2008 | La Regina, G.; D'Auria, F.; Tafi, Andrea; Piscitelli, F.; Olla, S.; Caporuscio, F.; Nencioni, L.; Cirilli, R.; LA TORRE, F.; Rodrigues De Melo, N.; Kelly, S.; Lamb, D.; Artico, M.; Botta, Maurizio; Palamara, A.; Silvestri, R. | - | |
| 158. Preparation of analogues of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine as antitubercular agents | 1-gen-2006 | Biava, Mariangela; Manetti, Fabrizio; Deidda, Delia; Pompei, Raffaello; Botta, Maurizio; Porretta, Giulio Cesare | - | |
| 2-Aminothiazolones as anti-hiv agents that act as gp120-cd4 inhibitors | 1-gen-2014 | Tiberi, Marika; Tintori, Cristina; Ceresola, Elisa Rita; Fazi, Roberta; Zamperini, Claudio; Calandro, Pierpaolo; Franchi, Luigi; Selvaraj, Manikandan; Botta, Lorenzo; Sampaolo, Michela; Saita, Diego; Ferrarese, Roberto; Clementi, Massimo; Canducci, Filippo; Botta, Maurizio | - | |
| 2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors | 1-gen-2010 | Dreassi, Elena; Zizzari, ALESSANDRA TANIA; Mori, Mattia; Filippi, Irene; Belfiore, Amalia; Naldini, Antonella; Carraro, Fabio; Santucci, Annalisa; Schenone, Silvia; Botta, Maurizio | - | |
| 3-Arilpiperazinilalchilpirrolo[3,2-d]pirimidin-2,4-dione: una nuova classe di ligandi potenti ed altamente selettivi per i recettori alfa1 adrenergici | 1-gen-2004 | V., Pittala'; M. A., Siracusa; L., Salerno; F., Guerrera; G., Romeo; F., Russo; A., Cagnotto; T., Mennini; Manetti, Fabrizio; Botta, Maurizio | - | |
| 3-Arylidene-N-hydroxyoxindoles: A New Class of Compounds Endowed with Antitumor Activity | 1-gen-2016 | Musso, Loana; Cincinelli, Raffaella; Zuco, Valentina; Decesare, Michelandrea; Zunino, Franco; Fallacara, ANNA LUCIA; Botta, Maurizio; Dallavalle, Sabrina | - | |
| 3D QSAR model on a set of selective A1 adenosine receptor (A1AR) antagonists | 1-gen-2004 | Manetti, Fabrizio; Tintori, Cristina; A., Martinelli; M. L., Trincavelli; S., Schenone; Botta, Maurizio | - | |
| 3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors | 1-gen-2008 | Falchi, F.; Manetti, Fabrizio; Schenone, S.; Botta, Maurizio | - | |
| 3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors | 1-gen-2009 | Falchi, F.; Manetti, Fabrizio; Carraro, Fabio; Naldini, Antonella; Maga, G.; Crespan, E.; Schenone, S.; Bruno, O.; Brullo, C.; Botta, Maurizio | - | |
| 3D QSAR models of interaction between b-tubulin and MSAAs: taxanes and epothilones | 1-gen-2003 | Maccari, L; Manetti, Fabrizio; Forli, S; Corelli, Federico; Botta, Maurizio | - | |
| 3D QSAR models of interactions between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA): a survey on taxanes and epothilones | 1-gen-2004 | Manetti, Fabrizio; L., Maccari; Corelli, Federico; Botta, Maurizio | - | |
| 3D QSAR studies for the β-tubulin binding site of microtubule-stabilizing anticancer agents (MSAAs): A pseudoreceptor model for taxanes based on the experimental structure of tubulin | 1-gen-2003 | Maccari, Laura; Manetti, Fabrizio; Corelli, Federico; Botta, Maurizio | - | |
| 3D QSAR studies of the interaction between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA). A combined pharmacophore generation and pseudoreceptor modeling approach applied to taxanes and epothilones | 1-gen-2003 | Manetti, Fabrizio; Forli, Stefano; Maccari, Laura; Corelli, Federico; Botta, Maurizio | - | |
| 4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling | 1-gen-2016 | Trist, Iuni M. L.; Nannetti, Giulio; Tintori, Cristina; Fallacara, ANNA LUCIA; Deodato, Davide; Mercorelli, Beatrice; Palù, Giorgio; Wijtmans, Maikel; Gospodova, Tzveta; Edink, Ewald; Verheij, Mark; De Esch, Iwan; Viteva, Lilia; Loregian, Arianna; Botta, Maurizio | - | |
| 4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof | 1-gen-2004 | Bondavalli, F; Botta, Maurizio; Manetti, Fabrizio; Donnini, Sandra; Schenone, S; Ziche, Marina | - |