IRIS
VALOTI, MASSIMO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 11.759
EU - Europa 8.638
AS - Asia 4.634
SA - Sud America 787
AF - Africa 178
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 7
Totale 26.024
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 11.616
GB - Regno Unito 1.999
RU - Federazione Russa 1.687
CN - Cina 1.683
SG - Singapore 1.490
IE - Irlanda 1.105
IT - Italia 958
BR - Brasile 653
SE - Svezia 629
UA - Ucraina 617
FR - Francia 530
DE - Germania 456
VN - Vietnam 366
HK - Hong Kong 346
FI - Finlandia 268
KR - Corea 219
TR - Turchia 111
IN - India 108
ES - Italia 104
ZA - Sudafrica 77
CA - Canada 72
BD - Bangladesh 63
BE - Belgio 46
AR - Argentina 43
MX - Messico 40
NL - Olanda 37
CZ - Repubblica Ceca 35
JP - Giappone 35
AT - Austria 33
NG - Nigeria 30
PL - Polonia 30
IQ - Iraq 27
SA - Arabia Saudita 23
EC - Ecuador 21
PK - Pakistan 21
CL - Cile 17
ID - Indonesia 17
AU - Australia 16
MA - Marocco 16
CO - Colombia 15
KE - Kenya 15
EG - Egitto 14
LT - Lituania 14
VE - Venezuela 14
GR - Grecia 13
AZ - Azerbaigian 12
IR - Iran 11
PE - Perù 11
UZ - Uzbekistan 11
CI - Costa d'Avorio 10
NP - Nepal 10
HU - Ungheria 9
JO - Giordania 9
RO - Romania 9
BG - Bulgaria 8
PH - Filippine 8
AE - Emirati Arabi Uniti 7
EE - Estonia 7
PY - Paraguay 7
TW - Taiwan 7
LB - Libano 6
MY - Malesia 6
CH - Svizzera 5
CR - Costa Rica 5
EU - Europa 5
IL - Israele 5
JM - Giamaica 5
KZ - Kazakistan 5
OM - Oman 5
AL - Albania 4
GE - Georgia 4
LV - Lettonia 4
NZ - Nuova Zelanda 4
PT - Portogallo 4
RS - Serbia 4
SK - Slovacchia (Repubblica Slovacca) 4
TT - Trinidad e Tobago 4
AO - Angola 3
BB - Barbados 3
BO - Bolivia 3
BY - Bielorussia 3
CM - Camerun 3
CY - Cipro 3
GT - Guatemala 3
HR - Croazia 3
TN - Tunisia 3
UY - Uruguay 3
DK - Danimarca 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
GA - Gabon 2
HN - Honduras 2
IM - Isola di Man 2
LK - Sri Lanka 2
LU - Lussemburgo 2
MD - Moldavia 2
NI - Nicaragua 2
NO - Norvegia 2
PS - Palestinian Territory 2
QA - Qatar 2
Totale 26.000
Salva come PNG Salva come JPEG
Città #
Southend 1.748
Fairfield 1.134
Dublin 1.092
Dallas 1.091
Singapore 846
Ashburn 794
Chandler 682
Woodbridge 541
Jacksonville 496
Wilmington 459
Moscow 455
Seattle 449
Santa Clara 434
Houston 418
Cambridge 404
Beijing 397
San Jose 371
Ann Arbor 361
Siena 340
Hong Kong 330
Hefei 220
Seoul 217
Princeton 200
The Dalles 191
Nanjing 173
Los Angeles 160
Menlo Park 136
New York 121
Helsinki 114
Lauterbourg 112
Fremont 107
Council Bluffs 105
Ho Chi Minh City 97
Dearborn 93
San Diego 88
Boardman 83
Hanoi 80
Milan 80
Izmir 78
Málaga 76
Nanchang 74
Munich 73
Florence 70
Johannesburg 70
Shanghai 69
São Paulo 65
San Mateo 58
Buffalo 57
Columbus 55
Brussels 45
Orem 39
Dong Ket 38
London 37
Tianjin 37
Frankfurt am Main 36
Hebei 35
Shenyang 35
Bengaluru 34
Redondo Beach 33
Turku 31
Tokyo 30
Brooklyn 29
Abuja 28
Rome 28
Lappeenranta 27
San Francisco 27
Jiaxing 26
Changsha 25
Vienna 25
Washington 25
Brno 24
Atlanta 22
Jinan 22
Warsaw 22
Denver 21
Phoenix 21
Chicago 20
Guangzhou 19
Redwood City 19
Rio de Janeiro 19
Zhengzhou 19
Brasília 17
Stockholm 17
Belo Horizonte 16
Chennai 16
Kunming 16
Montreal 16
Toronto 16
Da Nang 15
Norwalk 15
Haiphong 14
Manchester 14
Mexico City 14
Hangzhou 13
Nairobi 13
Poplar 13
Amsterdam 12
Boston 12
Nuremberg 12
Taizhou 12
Totale 17.135
Salva come PNG Salva come JPEG
Nome #
Effects on C57/BL mice of subchronic treatment with benzene [Effetto del trattamento subcronico con benzene in topi C57/Bl] 1.064
Prodrugs of pyrazolo[3,4-d]pyrimidines: from library synthesis to evaluation as potential anticancer agents in an orthotopic glioblastoma model 390
Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe 361
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 359
A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor 332
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 316
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 314
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 312
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 311
Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: Nanosystem approaches for drug delivery 306
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 303
Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach 298
CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction 293
Design, synthesis, biological activity and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study 291
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 287
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold 285
β-Naphtoflavone and Ethanol Induce Cytochrome P450 and Protect towards MPP⁺ Toxicity in Human Neuroblastoma SH-SY5Y Cells 279
Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents 274
Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors 273
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 270
Folate-targeted liposomal nitrooxy-doxorubicin: an effective tool against P-glycoprotein-positive and folate receptor-positive tumors 269
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 265
Antioxidant properties of PF9601N, a novel MAO-B inhibitor: assessment of its ability to interact with reactive nitrogen species 265
2,4,6-trinitrotoluene (TNT) with xenobiotic biotransformation system in European eel Anguilla anguilla (Linnaeus, 1758) 263
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy 260
Calcium antagonist and antiperoxidant properties of some hindered phenols 259
Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine 257
Antioxidant properties of propargylamine derivatives: assessment of their ability to scavenge peroxynitrite 256
Gold nanoparticles potentiate CaVchannel currents in rat tail artery myocytes 256
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents 256
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 254
Physiopathological Effects of the NO Donor 3-Morpholinosydnonimine on Rat Cortical Synaptosomes 253
Cyclooxygenase activity of hemoglobin. 253
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy 251
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 251
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 247
Gold nanoparticles uptake and cytotoxicity assessed on rat liver precision cut slices 243
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 241
Carotenoids: actual knowledge on food sources, intakes, stability and bioavailability and their protective role in humans 237
Synthesis and in vitro pharmacological activity of oxypropanol analogs of labetalol 237
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 237
Cancer cell permeability-glycoprotein as a target of MDR reverters: possible role of novel dihydropyridine derivatives 235
Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor 235
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 234
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 232
Development of MCM-41 mesoporous silica nanoparticles as a platform for pramipexole delivery 232
DP7, a novel dihydropyridine multidrug resistance reverter, shows only weak inhibitory activity on human CYP3A enzyme(s) 231
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 231
Merging computational modelling and experimental metabolite identification for toxicity prediction 230
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 226
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 224
The soy phytoestrogens genistein and daidzein as neuroprotective agents against anoxia-glucopenia and reperfusion damage in rat urinary bladder 221
Toxic injury to rat gut musculature following intraperitoneal administration of 2-t-butyl-4-methoxyphenol 218
Flavonoids and hERG channels: Friends or foes? 217
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 216
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 215
Anti-apoptotic effect of Mao-B inhibitor PF9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] is mediated by p53 pathway inhibition in MPP+-treated SH-SY5Y human dopaminergic cells 209
Gold nanoparticles uptake and cytotoxicity assessed on rat liver precision-cut slices 207
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 206
Effects of St John's wort and its active constituents, hypericin and hyperforin, on isolated rat urinary bladder 206
3,5-Di-t-butyl-4-hydroxyanisole (DTBHA) activation of rat skeletal muscle sarcoplasmic reticulum Ca2+-ATPase 202
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 202
Effect of loxiglumide (CR 1505) on CCK-induced contractions and 3H-acetylcholine release from guinea-pig gallbladder 199
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 198
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 196
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 195
BENZENE BONE MARROW TOXICITY AND EFFECTS ON LIVER ENZYMES OF C57BL/6 MICE 195
Pharmacokinetic of diphenydramine in young volunteers with a dimenhydrinate 25 mg chewing gum formulation 192
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 192
Expression, microsomal and mitochondrial activities of cytochrome P450 enzymes in brain regions from control and phenobarbital-treated rabbits 192
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 191
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes 190
Gender-related neuronal and smooth muscle damage of guinea pig isolated urinary bladder from anoxia-glucopenia and reperfusion injury and its relationship to glycogen content 189
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 187
Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration 186
Vanadate as an inhibitor of plant and mammalian peroxidases 185
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 185
Neuroprotection afforded by some hindered phenols and a-tocopherol in guinea-pig detrusor strips subjected to anoxia-glucopenia and reperfusion-like conditions. 184
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 183
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 183
Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds 182
Effects of 2,5-di-t-butyl-1,4-benzohydroquinone (BHQ) on rat aorta smooth muscle 181
Dehalogenation and N-dealkylation of chlorpromazine as revealed by plasma concentrations of metabolites in a population of chronically medicated schizophrenics 181
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect 180
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 179
Myorelaxant activity of 2-t-butyl-4-methoxyphenol (BHA) in guinea pig gastric fundus 178
Red wine alcohol promotes quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro 170
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 169
Peroxidase catalysed formation of prostaglandins from arachidonic acid 168
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 168
Synthesis and antiperoxidant activity of new phenolic O-glycosides 167
Heteroaryl-substituted phenols as potential antioxidants 166
Functionalized mesoporous silica nanoparticles for oral delivery of budesonide 164
Evidence of a coupled mechanism between monoamine oxidase and peroxidase in the metabolism of tyramine by rat intestinal mitochondria 163
Oxidative ring-coupling of tyrosine and its derivatives by purified rat intestinal peroxidase 159
Purification and characterization of rat intestinal peroxidase. Its activity towards 2-t-butyl-4-methoxyphenol (BHA) 158
Reversible monoacylglycerol lipase inhibitors: discovery of a new class of benzylpiperidine derivatives 158
Synthetic approach, regio- and stereochemical characterisation and differentiation of new potential antioxidant C- and O- arylglycosides 157
Gold nanoparticles toxicity in rat precision-cut liver slices: a preliminary study 157
Thin layer chromatography in the quantitative analysis of pharmaceuticals. Comparison of layers in the analysis of complex mixtures of phenothiazine derivatives 156
Totale 23.640
Salva come PNG Salva come JPEG
Categoria #
all - tutte 79.424
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 79.424
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021154 0 0 0 0 0 0 0 0 0 0 0 154
2021/20221.869 165 222 138 161 96 62 117 96 77 209 183 343
2022/20232.501 151 219 337 386 196 443 61 220 265 108 74 41
2023/20241.780 85 32 157 112 69 484 584 60 4 35 36 122
2024/20253.440 106 164 320 207 419 199 122 238 307 148 361 849
2025/20268.193 596 1.100 841 840 1.554 298 838 244 315 396 1.069 102
Totale 26.283