IRIS
FROSINI, MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 6.772
EU - Europa 6.244
AS - Asia 1.038
AF - Africa 14
OC - Oceania 11
SA - Sud America 8
Continente sconosciuto - Info sul continente non disponibili 6
Totale 14.093
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Nazione #
US - Stati Uniti d'America 6.744
GB - Regno Unito 2.049
IE - Irlanda 1.041
CN - Cina 736
IT - Italia 650
SE - Svezia 591
UA - Ucraina 559
DE - Germania 357
RU - Federazione Russa 330
FR - Francia 290
FI - Finlandia 188
SG - Singapore 106
VN - Vietnam 81
TR - Turchia 69
ES - Italia 53
CZ - Repubblica Ceca 31
BE - Belgio 26
CA - Canada 23
GR - Grecia 15
IN - India 12
AU - Australia 11
CI - Costa d'Avorio 10
IR - Iran 10
NL - Olanda 10
RO - Romania 10
HU - Ungheria 9
AT - Austria 8
EU - Europa 6
BG - Bulgaria 4
DK - Danimarca 4
MX - Messico 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
KR - Corea 3
SA - Arabia Saudita 3
AM - Armenia 2
AR - Argentina 2
BD - Bangladesh 2
BR - Brasile 2
CL - Cile 2
EG - Egitto 2
IL - Israele 2
LV - Lettonia 2
MD - Moldavia 2
NO - Norvegia 2
PK - Pakistan 2
PL - Polonia 2
RS - Serbia 2
CY - Cipro 1
EC - Ecuador 1
EE - Estonia 1
GH - Ghana 1
ID - Indonesia 1
IM - Isola di Man 1
JP - Giappone 1
KH - Cambogia 1
KZ - Kazakistan 1
LU - Lussemburgo 1
MK - Macedonia 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 14.093
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Città #
Southend 1.897
Fairfield 1.111
Dublin 1.028
Ashburn 614
Chandler 545
Wilmington 479
Woodbridge 469
Houston 455
Jacksonville 439
Seattle 414
Cambridge 401
Ann Arbor 310
Siena 256
Princeton 183
Nanjing 171
Beijing 150
Boardman 94
Helsinki 87
Fremont 81
Dong Ket 78
San Mateo 78
San Diego 73
Singapore 65
Izmir 62
Moscow 55
Nanchang 54
Málaga 51
New York 51
Shanghai 46
Dearborn 41
Menlo Park 40
Shenyang 38
Tianjin 35
London 31
Hebei 29
Jinan 29
Florence 27
Brussels 26
Milan 26
Washington 25
Hangzhou 20
Jiaxing 20
Brno 18
Norwalk 18
San Francisco 17
Taizhou 17
Zhengzhou 17
Redwood City 15
Lappeenranta 14
Los Angeles 14
Changsha 13
Guangzhou 13
Munich 13
Rome 13
Düsseldorf 11
Abidjan 10
Chicago 10
Kunming 10
Mestre 10
Olomouc 10
Toronto 10
Dallas 9
Latina 9
Ningbo 9
San Costantino Calabro 9
Tappahannock 9
Changchun 8
Hefei 8
Torino 8
Vienna 8
Auburn Hills 7
Berlin 7
Canberra 7
Falls Church 7
Naples 7
Nottingham 7
Venezia 7
Budapest 6
Lancaster 6
Zanjan 6
Bari 5
Candiolo 5
Cerreto Guidi 5
Galatone 5
Kilburn 5
Lamezia Terme 5
Lanzhou 5
Leawood 5
Scarperia 5
Acton 4
Ambrogio 4
Andover 4
Arconate 4
Edinburgh 4
Falkenstein 4
Frankfurt am Main 4
Horia 4
Hounslow 4
Montefalco 4
Paris 4
Totale 10.670
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Nome #
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 280
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors 256
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 254
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 237
The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo. 223
Resveratrol: from diet to topical usage 208
Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage 191
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 184
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 181
Calcium and taurine interaction in mammalian brain metabolism 181
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 181
Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies 175
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 173
Effects of taurine and structurally related analogues on Ca2+ uptake and respiration rate in rat liver mitochondria 170
In vitro assessement of tariquidar toxicity towards vasculature 167
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 166
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields 164
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 162
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors 162
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies 159
In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies 158
Changes in CSF composition during heat stress and fever in conscious rabbits 156
The in vivo release of taurine in the striatonigral pathway 155
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 155
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects 154
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 153
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 153
Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein 153
Possible involvement of brain calcium metabolism in the action of taurine in mammalian thermoregulation 152
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 152
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 150
Calcium channel antagonists discovered by a multidisciplinary approach 148
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 147
Human tuberculosis I. epidemiology, diagnosis and pathogenetic mechanisms 146
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 146
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 146
Synthesis of taurine analogues from alkenes 141
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 140
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 140
Potentiation of mitochondrial Ca2+ sequestration by taurine 139
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 138
Effects of aqueous extract of lycopersicum esculentum L. var. “Camone” tomato on blood pressure, behavior and brain susceptibility to oxidative stress in spontaneously hypertensive rats 138
Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs 137
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 136
Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines. 135
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 135
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 134
Apoptotic-induced Effects of Castanea sativa Bark Extract in Human SH-SY5Y Neuroblastoma Cells 134
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 133
Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury 130
Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells 130
The mitochondrial permeability transition and taurine 129
Selective ozone concentrations may reduce the ischemic damage after a stroke 129
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 128
Neuroprotective Effects of Castanea sativa Mill. Bark Extract in Human Neuroblastoma Cells Subjected to Oxidative Stress 128
Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig 128
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 126
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 126
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 125
Role of taurine in thermoregulation and motor control. Behavioural and cellular studies 124
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 123
Effects of bacterial endotoxin, interleukin-1 and prostaglandins on thermoregulation and cerebrospinal fluid-calcium concentration in rabbits 123
Antagonism by taurine on the ruthenium red-induced and 6-hydroxydopamine plus 1-methyl-4-phenylpyridinium-induced Ca2+ release from rat liver mitochondria 121
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 121
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 121
3,5-di-t-butylcatechol (DTCAT) as an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC) 119
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives. 119
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 117
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 117
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker 116
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect. 116
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 115
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes. 111
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations 110
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 110
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 108
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA 108
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles 108
null 106
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From calcium-channel modulators properties to multidrug-resistance reverting activity 106
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 106
Playing with opening and closing of heterocycles: using the Cusmano-Ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors. 105
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 103
null 103
In vivo release of taurine from rat neostriatum and substantia nigra 102
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 99
Effect of the endocrine disruptor Bisphenol A in in vitro models of human placenta 98
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 98
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening 96
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 93
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 92
Olive leaves and hibiscus flowers extracts-based preparation protect brain from oxidative stress-induced injury 91
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 90
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 89
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 89
Nitric oxide modulation of interleukin-1[beta]-evoked intracellular Ca2+ release in human astrocytoma U-373 MG cells and brain striatal slices. 88
Apoptotic-induced effects of acacia catechu willd. Extract in human colon cancer cells 87
Calcium changes in rabbit CSF during endotoxin, IL-1 beta, and PGE2 fever 85
Iron(III) complexing ability of new ligands based on natural γ-pyrone maltol 82
Pharmacokinetic of diphenydramine in young volunteers with a dimenhydrinate 25 mg chewing gum formulation 78
Totale 13.650
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Categoria #
all - tutte 46.367
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.367
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.508 0 0 166 433 232 281 267 346 300 238 85 160
2020/20212.656 149 244 72 250 240 336 87 327 235 280 248 188
2021/20221.629 104 187 134 139 99 50 93 92 82 180 157 312
2022/20232.122 127 185 308 297 164 400 37 196 233 79 66 30
2023/20241.723 70 31 157 74 95 432 559 34 13 41 50 167
2024/2025501 108 154 239 0 0 0 0 0 0 0 0 0
Totale 14.384