IRIS
FROSINI, MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 10.133
EU - Europa 8.359
AS - Asia 4.705
SA - Sud America 797
AF - Africa 149
OC - Oceania 22
Continente sconosciuto - Info sul continente non disponibili 6
Totale 24.171
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Nazione #
US - Stati Uniti d'America 9.990
GB - Regno Unito 2.160
CN - Cina 1.668
RU - Federazione Russa 1.566
SG - Singapore 1.476
IE - Irlanda 1.045
IT - Italia 898
BR - Brasile 653
SE - Svezia 603
UA - Ucraina 576
DE - Germania 463
VN - Vietnam 452
FR - Francia 436
HK - Hong Kong 353
FI - Finlandia 244
KR - Corea 227
IN - India 140
TR - Turchia 97
CA - Canada 77
ES - Italia 75
ZA - Sudafrica 73
AR - Argentina 63
BD - Bangladesh 61
NL - Olanda 50
MX - Messico 41
IQ - Iraq 36
CZ - Repubblica Ceca 34
AT - Austria 33
BE - Belgio 28
PL - Polonia 26
EC - Ecuador 25
ID - Indonesia 23
JP - Giappone 21
PK - Pakistan 21
AU - Australia 20
NG - Nigeria 20
BG - Bulgaria 17
CL - Cile 16
GR - Grecia 16
IR - Iran 16
AE - Emirati Arabi Uniti 13
MA - Marocco 13
CO - Colombia 12
RO - Romania 12
CI - Costa d'Avorio 11
JO - Giordania 11
LT - Lituania 11
SA - Arabia Saudita 11
HU - Ungheria 10
KE - Kenya 10
EG - Egitto 9
NP - Nepal 9
PE - Perù 9
UZ - Uzbekistan 9
CH - Svizzera 8
DK - Danimarca 8
EE - Estonia 7
LB - Libano 7
MY - Malesia 7
PY - Paraguay 7
VE - Venezuela 7
EU - Europa 6
LV - Lettonia 6
AZ - Azerbaigian 5
IL - Israele 5
JM - Giamaica 5
TN - Tunisia 5
CY - Cipro 4
HN - Honduras 4
KH - Cambogia 4
KZ - Kazakistan 4
NO - Norvegia 4
OM - Oman 4
PA - Panama 4
PH - Filippine 4
PT - Portogallo 4
RS - Serbia 4
BY - Bielorussia 3
DZ - Algeria 3
HR - Croazia 3
MN - Mongolia 3
QA - Qatar 3
AM - Armenia 2
BB - Barbados 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
GY - Guiana 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
SV - El Salvador 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BO - Bolivia 1
ET - Etiopia 1
Totale 24.156
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Città #
Southend 1.897
Fairfield 1.111
Dublin 1.032
Dallas 976
Ashburn 826
Singapore 771
Chandler 545
Wilmington 481
Woodbridge 469
Houston 463
Jacksonville 443
Moscow 420
Seattle 418
Santa Clara 407
Cambridge 401
San Jose 393
Beijing 389
Hong Kong 341
Ann Arbor 310
Siena 276
Hefei 259
Seoul 223
Princeton 183
Nanjing 171
The Dalles 161
Los Angeles 142
Ho Chi Minh City 137
Council Bluffs 120
Helsinki 116
Lauterbourg 103
Boardman 97
New York 90
Hanoi 85
Fremont 82
Dong Ket 78
San Mateo 78
San Diego 74
Milan 73
Johannesburg 66
Izmir 64
São Paulo 63
Shanghai 60
Florence 59
Munich 58
London 54
Nanchang 54
Buffalo 51
Málaga 51
Columbus 50
Bengaluru 43
Tianjin 42
Dearborn 41
Menlo Park 40
Orem 40
Shenyang 39
Chicago 38
Redondo Beach 33
San Francisco 31
Hebei 29
Jinan 29
Brussels 28
Washington 27
Chennai 26
Guangzhou 26
Turku 26
Frankfurt am Main 25
Rome 25
Hangzhou 24
Montreal 23
Zhengzhou 22
Atlanta 21
Changsha 21
Rio de Janeiro 21
Toronto 21
Abuja 20
Jiaxing 20
Belo Horizonte 19
Brno 19
Brooklyn 19
Lappeenranta 19
Nuremberg 19
Tokyo 19
Vienna 19
Warsaw 19
Norwalk 18
Taizhou 18
Da Nang 17
Manchester 17
Poplar 17
Baghdad 16
Boston 16
Curitiba 15
Mexico City 15
Redwood City 15
Amsterdam 13
Mumbai 13
Stockholm 13
Canberra 12
Düsseldorf 12
Jakarta 12
Totale 16.443
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Nome #
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 401
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors 384
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 359
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 337
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 316
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 314
Resveratrol: from diet to topical usage 304
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 303
Effects of aqueous extract of lycopersicum esculentum L. var. “Camone” tomato on blood pressure, behavior and brain susceptibility to oxidative stress in spontaneously hypertensive rats 294
The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo. 290
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 287
Calcium and taurine interaction in mammalian brain metabolism 284
Effects of taurine and structurally related analogues on Ca2+ uptake and respiration rate in rat liver mitochondria 279
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields 270
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 270
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 265
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 254
Calcium channel antagonists discovered by a multidisciplinary approach 252
In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies 251
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 251
In vitro assessement of tariquidar toxicity towards vasculature 249
Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage 248
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 247
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors 243
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 241
Human tuberculosis I. epidemiology, diagnosis and pathogenetic mechanisms 238
Changes in CSF composition during heat stress and fever in conscious rabbits 238
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 237
Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein 236
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 234
3,5-di-t-butylcatechol (DTCAT) as an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC) 233
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 232
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 231
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 228
Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies 227
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 226
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 224
Antagonism by taurine on the ruthenium red-induced and 6-hydroxydopamine plus 1-methyl-4-phenylpyridinium-induced Ca2+ release from rat liver mitochondria 222
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies 222
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 221
Potentiation of mitochondrial Ca2+ sequestration by taurine 218
The in vivo release of taurine in the striatonigral pathway 218
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects 218
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 216
Apoptotic-induced Effects of Castanea sativa Bark Extract in Human SH-SY5Y Neuroblastoma Cells 216
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 215
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 214
Effect of the endocrine disruptor Bisphenol A in in vitro models of human placenta 214
Possible involvement of brain calcium metabolism in the action of taurine in mammalian thermoregulation 210
Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells 208
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 206
Calcium changes in rabbit CSF during endotoxin, IL-1 beta, and PGE2 fever 206
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 204
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 204
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 202
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 200
Selective ozone concentrations may reduce the ischemic damage after a stroke 200
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker 199
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 198
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 198
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 198
The mitochondrial permeability transition and taurine 197
Role of taurine in thermoregulation and motor control. Behavioural and cellular studies 196
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 196
Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents 195
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 195
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 194
Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines. 193
Pharmacokinetic of diphenydramine in young volunteers with a dimenhydrinate 25 mg chewing gum formulation 192
Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury 192
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 192
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 191
Synthesis of taurine analogues from alkenes 190
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes 190
Effects of bacterial endotoxin, interleukin-1 and prostaglandins on thermoregulation and cerebrospinal fluid-calcium concentration in rabbits 190
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 187
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 185
Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs 184
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 183
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 183
Apoptotic-induced effects of acacia catechu willd. Extract in human colon cancer cells 182
Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig 181
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives 180
Neuroprotective Effects of Castanea sativa Mill. Bark Extract in Human Neuroblastoma Cells Subjected to Oxidative Stress 180
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect 180
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From calcium-channel modulators properties to multidrug-resistance reverting activity 180
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 179
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA 169
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 169
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 168
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles 167
Playing with opening and closing of heterocycles: using the Cusmano-Ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors 165
Olive leaves and hibiscus flowers extracts-based preparation protect brain from oxidative stress-induced injury 164
Effect of the endocrine distruptor Bisphenonol in "in vitro" models of human placenta 158
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening 157
In vivo release of taurine from rat neostriatum and substantia nigra 157
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 155
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations 152
In vitro and in silico analysis of the vascular effects of asymmetrical N,N-bis(alkanol)amine aryl esters, novel multidrug resistance-reverting agents 147
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme 146
Totale 21.965
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Categoria #
all - tutte 76.124
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 76.124
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021188 0 0 0 0 0 0 0 0 0 0 0 188
2021/20221.629 104 187 134 139 99 50 93 92 82 180 157 312
2022/20232.122 127 185 308 297 164 400 37 196 233 79 66 30
2023/20241.723 70 31 157 74 95 432 559 34 13 41 50 167
2024/20253.391 108 154 309 200 437 197 127 208 329 189 335 798
2025/20267.220 635 1.046 806 812 1.444 241 884 267 337 430 202 116
Totale 24.494