IRIS
FROSINI, MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 10.708
EU - Europa 8.889
AS - Asia 4.736
SA - Sud America 802
Continente sconosciuto - Info sul continente non disponibili 329
AF - Africa 151
OC - Oceania 22
Totale 25.637
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Nazione #
US - Stati Uniti d'America 10.548
GB - Regno Unito 2.161
CN - Cina 1.678
RU - Federazione Russa 1.566
SG - Singapore 1.488
IT - Italia 1.419
IE - Irlanda 1.045
BR - Brasile 656
SE - Svezia 607
UA - Ucraina 576
DE - Germania 463
VN - Vietnam 453
FR - Francia 437
HK - Hong Kong 356
FI - Finlandia 244
KR - Corea 227
IN - India 141
TR - Turchia 97
CA - Canada 84
ES - Italia 75
ZA - Sudafrica 73
AR - Argentina 63
BD - Bangladesh 63
NL - Olanda 52
MX - Messico 42
IQ - Iraq 36
CZ - Repubblica Ceca 34
AT - Austria 33
BE - Belgio 28
PL - Polonia 26
EC - Ecuador 25
ID - Indonesia 23
JP - Giappone 21
PK - Pakistan 21
AU - Australia 20
NG - Nigeria 20
BG - Bulgaria 17
CL - Cile 16
GR - Grecia 16
IR - Iran 16
CO - Colombia 14
AE - Emirati Arabi Uniti 13
MA - Marocco 13
RO - Romania 13
CI - Costa d'Avorio 11
JO - Giordania 11
LT - Lituania 11
SA - Arabia Saudita 11
HU - Ungheria 10
KE - Kenya 10
EG - Egitto 9
NP - Nepal 9
PE - Perù 9
UZ - Uzbekistan 9
CH - Svizzera 8
DK - Danimarca 8
EE - Estonia 7
LB - Libano 7
MY - Malesia 7
PY - Paraguay 7
VE - Venezuela 7
EU - Europa 6
JM - Giamaica 6
LV - Lettonia 6
AZ - Azerbaigian 5
HN - Honduras 5
IL - Israele 5
PH - Filippine 5
TN - Tunisia 5
CY - Cipro 4
KH - Cambogia 4
KZ - Kazakistan 4
NO - Norvegia 4
OM - Oman 4
PA - Panama 4
PT - Portogallo 4
RS - Serbia 4
BY - Bielorussia 3
CR - Costa Rica 3
DZ - Algeria 3
HR - Croazia 3
MN - Mongolia 3
QA - Qatar 3
SV - El Salvador 3
AM - Armenia 2
BB - Barbados 2
DO - Repubblica Dominicana 2
GT - Guatemala 2
GY - Guiana 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
SC - Seychelles 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
Totale 25.293
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Città #
Southend 1.897
Fairfield 1.111
Dublin 1.032
Dallas 981
Ashburn 946
Singapore 778
Chandler 545
Wilmington 482
Woodbridge 469
Houston 464
Jacksonville 444
Santa Clara 442
San Jose 423
Moscow 420
Seattle 420
Cambridge 401
Beijing 392
Milan 379
Hong Kong 342
Ann Arbor 310
Siena 276
Council Bluffs 273
Hefei 259
Seoul 223
Princeton 183
Nanjing 171
The Dalles 161
Los Angeles 145
Ho Chi Minh City 137
Rome 118
Helsinki 116
Lauterbourg 103
Boardman 99
New York 96
Hanoi 86
Fremont 82
Dong Ket 78
San Mateo 78
Columbus 76
San Diego 74
Johannesburg 66
Izmir 64
São Paulo 64
Florence 61
Shanghai 61
Munich 58
London 55
Nanchang 54
Buffalo 51
Málaga 51
Bengaluru 43
Chicago 43
Tianjin 42
Dearborn 41
Menlo Park 40
Orem 40
Shenyang 39
Redondo Beach 33
San Francisco 33
Hebei 29
Jinan 29
Brussels 28
Figino 28
Washington 28
Chennai 26
Guangzhou 26
Turku 26
Frankfurt am Main 25
Atlanta 24
Hangzhou 24
Montreal 24
Zhengzhou 22
Changsha 21
Rio de Janeiro 21
Toronto 21
Abuja 20
Jiaxing 20
Belo Horizonte 19
Boston 19
Brno 19
Brooklyn 19
Lappeenranta 19
Nuremberg 19
Tokyo 19
Vienna 19
Warsaw 19
Naples 18
Norwalk 18
Taizhou 18
Turin 18
Da Nang 17
Manchester 17
Phoenix 17
Poplar 17
Baghdad 16
Mexico City 16
Curitiba 15
Redwood City 15
Mumbai 14
Amsterdam 13
Totale 17.293
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Nome #
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 413
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors 397
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 370
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 352
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 328
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 324
Resveratrol: from diet to topical usage 316
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 307
Effects of aqueous extract of lycopersicum esculentum L. var. “Camone” tomato on blood pressure, behavior and brain susceptibility to oxidative stress in spontaneously hypertensive rats 303
The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo 300
Effects of taurine and structurally related analogues on Ca2+ uptake and respiration rate in rat liver mitochondria 291
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 290
Calcium and taurine interaction in mammalian brain metabolism 287
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 284
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields 279
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 269
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 268
Calcium channel antagonists discovered by a multidisciplinary approach 260
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 258
In vitro assessement of tariquidar toxicity towards vasculature 258
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 257
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 257
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors 256
In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies 255
Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage 253
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 249
Human tuberculosis I. epidemiology, diagnosis and pathogenetic mechanisms 248
Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein 246
3,5-di-t-butylcatechol (DTCAT) as an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC) 245
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 245
Changes in CSF composition during heat stress and fever in conscious rabbits 242
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 239
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 237
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 237
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 236
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 233
Antagonism by taurine on the ruthenium red-induced and 6-hydroxydopamine plus 1-methyl-4-phenylpyridinium-induced Ca2+ release from rat liver mitochondria 230
The in vivo release of taurine in the striatonigral pathway 230
Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies 230
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies 230
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 229
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 228
Effect of the endocrine disruptor Bisphenol A in in vitro models of human placenta 228
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects 227
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 225
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 222
Potentiation of mitochondrial Ca2+ sequestration by taurine 221
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 221
Apoptotic-induced Effects of Castanea sativa Bark Extract in Human SH-SY5Y Neuroblastoma Cells 221
Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents 217
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 216
Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells 215
Possible involvement of brain calcium metabolism in the action of taurine in mammalian thermoregulation 213
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 212
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 212
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 212
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 211
Selective ozone concentrations may reduce the ischemic damage after a stroke 211
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker 209
Calcium changes in rabbit CSF during endotoxin, IL-1 beta, and PGE2 fever 208
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 207
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 206
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes 205
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 205
Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury 205
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 205
Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines 203
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 203
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 203
The mitochondrial permeability transition and taurine 202
Effects of bacterial endotoxin, interleukin-1 and prostaglandins on thermoregulation and cerebrospinal fluid-calcium concentration in rabbits 202
Pharmacokinetic of diphenydramine in young volunteers with a dimenhydrinate 25 mg chewing gum formulation 200
Synthesis of taurine analogues from alkenes 199
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 199
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 198
Role of taurine in thermoregulation and motor control. Behavioural and cellular studies 198
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 193
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From calcium-channel modulators properties to multidrug-resistance reverting activity 193
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 191
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives 191
Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig 191
Apoptotic-induced effects of acacia catechu willd. Extract in human colon cancer cells 190
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 189
Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs 188
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 188
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 187
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect 183
Neuroprotective Effects of Castanea sativa Mill. Bark Extract in Human Neuroblastoma Cells Subjected to Oxidative Stress 182
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 181
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA 178
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles 172
Effect of the endocrine distruptor Bisphenonol in "in vitro" models of human placenta 171
Playing with opening and closing of heterocycles: using the Cusmano-Ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors 169
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening 167
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 167
In vivo release of taurine from rat neostriatum and substantia nigra 166
Olive leaves and hibiscus flowers extracts-based preparation protect brain from oxidative stress-induced injury 165
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations 162
Serum Metabolomics and Proteomics to Study the Antihypertensive Effect of Protein Extracts from Tenebrio molitor 160
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme 158
Totale 22.889
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Categoria #
all - tutte 79.857
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 79.857
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.525 0 187 134 139 99 50 93 92 82 180 157 312
2022/20232.122 127 185 308 297 164 400 37 196 233 79 66 30
2023/20241.723 70 31 157 74 95 432 559 34 13 41 50 167
2024/20253.391 108 154 309 200 437 197 127 208 329 189 335 798
2025/20267.769 635 1.046 806 812 1.444 241 884 267 337 430 202 665
2026/2027594 400 194 0 0 0 0 0 0 0 0 0 0
Totale 25.637