IRIS
FROSINI, MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 6.677
EU - Europa 5.746
AS - Asia 919
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 6
SA - Sud America 6
AF - Africa 3
Totale 13.368
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Nazione #
US - Stati Uniti d'America 6.652
GB - Regno Unito 2.043
IE - Irlanda 1.040
CN - Cina 728
SE - Svezia 591
IT - Italia 559
UA - Ucraina 559
DE - Germania 337
FR - Francia 283
FI - Finlandia 169
VN - Vietnam 81
TR - Turchia 69
ES - Italia 53
BE - Belgio 25
CA - Canada 21
RU - Federazione Russa 20
GR - Grecia 14
AU - Australia 11
IR - Iran 10
RO - Romania 10
IN - India 9
NL - Olanda 8
AT - Austria 7
HU - Ungheria 7
EU - Europa 6
SG - Singapore 5
BG - Bulgaria 4
MX - Messico 4
DK - Danimarca 3
KR - Corea 3
SA - Arabia Saudita 3
BD - Bangladesh 2
BR - Brasile 2
CH - Svizzera 2
CL - Cile 2
CZ - Repubblica Ceca 2
EG - Egitto 2
MD - Moldavia 2
PK - Pakistan 2
RS - Serbia 2
AE - Emirati Arabi Uniti 1
AR - Argentina 1
CY - Cipro 1
EE - Estonia 1
GH - Ghana 1
ID - Indonesia 1
IL - Israele 1
IM - Isola di Man 1
JP - Giappone 1
KZ - Kazakistan 1
LU - Lussemburgo 1
MK - Macedonia 1
MY - Malesia 1
PE - Perù 1
PL - Polonia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 13.368
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Città #
Southend 1.897
Fairfield 1.111
Dublin 1.027
Ashburn 610
Chandler 545
Wilmington 479
Woodbridge 469
Houston 455
Jacksonville 439
Seattle 413
Cambridge 401
Ann Arbor 310
Siena 249
Princeton 183
Nanjing 171
Beijing 150
Helsinki 82
Fremont 81
Dong Ket 78
San Mateo 78
San Diego 73
Boardman 63
Izmir 62
Nanchang 54
Málaga 51
New York 50
Shanghai 44
Dearborn 41
Menlo Park 40
Shenyang 38
Tianjin 35
London 30
Hebei 29
Jinan 29
Brussels 25
Washington 25
Milan 23
Hangzhou 20
Jiaxing 20
Norwalk 18
Taizhou 17
Zhengzhou 17
Redwood City 15
San Francisco 15
Florence 14
Changsha 13
Guangzhou 13
Rome 13
Düsseldorf 11
Kunming 10
Mestre 10
Toronto 10
Latina 9
Ningbo 9
Tappahannock 9
Changchun 8
Hefei 8
Torino 8
Auburn Hills 7
Canberra 7
Falls Church 7
Nottingham 7
Venezia 7
Vienna 7
Budapest 6
Lancaster 6
Zanjan 6
Berlin 5
Candiolo 5
Cerreto Guidi 5
Chicago 5
Galatone 5
Kilburn 5
Lamezia Terme 5
Lanzhou 5
Leawood 5
Los Angeles 5
Scarperia 5
Acton 4
Ambrogio 4
Andover 4
Arconate 4
Edinburgh 4
Falkenstein 4
Horia 4
Hounslow 4
Montefalco 4
Redmond 4
Scandicci 4
Turku 4
Bonndorf 3
Detroit 3
Empoli 3
Marino 3
Melbourne 3
Montemiletto 3
Mountain View 3
Naples 3
Terni 3
Winnipeg 3
Totale 10.400
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Nome #
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 270
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 249
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors 245
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 231
The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo. 220
Resveratrol: from diet to topical usage 202
Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage 189
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 178
Calcium and taurine interaction in mammalian brain metabolism 175
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 172
Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies 168
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 166
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 165
Effects of taurine and structurally related analogues on Ca2+ uptake and respiration rate in rat liver mitochondria 164
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 162
In vitro assessement of tariquidar toxicity towards vasculature 161
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 160
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields 159
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies 156
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors 155
The in vivo release of taurine in the striatonigral pathway 152
In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies 152
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 151
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects 150
Changes in CSF composition during heat stress and fever in conscious rabbits 150
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 149
Possible involvement of brain calcium metabolism in the action of taurine in mammalian thermoregulation 148
Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein 148
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 147
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 143
Calcium channel antagonists discovered by a multidisciplinary approach 141
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 141
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 140
Human tuberculosis I. epidemiology, diagnosis and pathogenetic mechanisms 140
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 139
Synthesis of taurine analogues from alkenes 138
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 138
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 136
Potentiation of mitochondrial Ca2+ sequestration by taurine 134
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 134
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 134
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 132
Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines. 131
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 131
Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs 129
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 129
Apoptotic-induced Effects of Castanea sativa Bark Extract in Human SH-SY5Y Neuroblastoma Cells 129
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice. 128
The mitochondrial permeability transition and taurine 127
Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig 126
Neuroprotective Effects of Castanea sativa Mill. Bark Extract in Human Neuroblastoma Cells Subjected to Oxidative Stress 125
Selective ozone concentrations may reduce the ischemic damage after a stroke 125
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 124
Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury 124
Role of taurine in thermoregulation and motor control. Behavioural and cellular studies 123
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 122
Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells 122
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 120
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 120
Effects of bacterial endotoxin, interleukin-1 and prostaglandins on thermoregulation and cerebrospinal fluid-calcium concentration in rabbits 118
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives. 117
Effects of aqueous extract of lycopersicum esculentum L. var. “Camone” tomato on blood pressure, behavior and brain susceptibility to oxidative stress in spontaneously hypertensive rats 117
Antagonism by taurine on the ruthenium red-induced and 6-hydroxydopamine plus 1-methyl-4-phenylpyridinium-induced Ca2+ release from rat liver mitochondria 115
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 113
3,5-di-t-butylcatechol (DTCAT) as an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC). 112
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 112
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 112
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 112
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 111
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker 110
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect. 110
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations. 108
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 108
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes. 107
null 106
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles 105
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA 104
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 103
null 103
Playing with opening and closing of heterocycles: using the Cusmano-Ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors. 103
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 102
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From calcium-channel modulators properties to multidrug-resistance reverting activity 101
In vivo release of taurine from rat neostriatum and substantia nigra 99
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 98
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening 92
Effect of the endocrine disruptor Bisphenol A in in vitro models of human placenta 91
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 87
Olive leaves and hibiscus flowers extracts-based preparation protect brain from oxidative stress-induced injury 86
Nitric oxide modulation of interleukin-1[beta]-evoked intracellular Ca2+ release in human astrocytoma U-373 MG cells and brain striatal slices. 85
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 84
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 83
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 83
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 82
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 80
Calcium changes in rabbit CSF during endotoxin, IL-1 beta, and PGE2 fever 79
Apoptotic-induced effects of acacia catechu willd. Extract in human colon cancer cells 79
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 76
Pharmacokinetic of diphenydramine in young volunteers with a dimenhydrinate 25 mg chewing gum formulation 73
Effect of the endocrine distruptor Bisphenonol in "in vitro" models of human placenta 73
Iron(III) complexing ability of new ligands based on natural γ-pyrone maltol 72
Totale 13.030
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Categoria #
all - tutte 41.235
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.235
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.075 0 0 0 0 0 0 0 0 0 234 447 394
2019/20202.988 374 106 166 433 232 281 267 346 300 238 85 160
2020/20212.656 149 244 72 250 240 336 87 327 235 280 248 188
2021/20221.629 104 187 134 139 99 50 93 92 82 180 157 312
2022/20232.122 127 185 308 297 164 400 37 196 233 79 66 30
2023/20241.480 70 31 157 74 95 432 559 34 13 15 0 0
Totale 13.640