IRIS
FROSINI, MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 9.839
EU - Europa 8.325
AS - Asia 4.654
SA - Sud America 797
AF - Africa 149
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 6
Totale 23.791
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Nazione #
US - Stati Uniti d'America 9.708
GB - Regno Unito 2.157
CN - Cina 1.648
RU - Federazione Russa 1.566
SG - Singapore 1.461
IE - Irlanda 1.045
IT - Italia 867
BR - Brasile 653
SE - Svezia 603
UA - Ucraina 576
DE - Germania 463
VN - Vietnam 452
FR - Francia 436
HK - Hong Kong 349
FI - Finlandia 244
KR - Corea 227
IN - India 139
TR - Turchia 97
ES - Italia 75
ZA - Sudafrica 73
CA - Canada 68
AR - Argentina 63
BD - Bangladesh 51
NL - Olanda 50
MX - Messico 39
IQ - Iraq 36
CZ - Repubblica Ceca 34
AT - Austria 33
BE - Belgio 28
PL - Polonia 26
EC - Ecuador 25
ID - Indonesia 23
JP - Giappone 21
PK - Pakistan 21
NG - Nigeria 20
AU - Australia 19
BG - Bulgaria 17
CL - Cile 16
GR - Grecia 16
IR - Iran 16
AE - Emirati Arabi Uniti 13
MA - Marocco 13
CO - Colombia 12
RO - Romania 12
CI - Costa d'Avorio 11
JO - Giordania 11
LT - Lituania 11
SA - Arabia Saudita 11
HU - Ungheria 10
KE - Kenya 10
EG - Egitto 9
NP - Nepal 9
PE - Perù 9
UZ - Uzbekistan 9
CH - Svizzera 8
DK - Danimarca 8
EE - Estonia 7
LB - Libano 7
MY - Malesia 7
PY - Paraguay 7
VE - Venezuela 7
EU - Europa 6
LV - Lettonia 6
AZ - Azerbaigian 5
IL - Israele 5
TN - Tunisia 5
CY - Cipro 4
HN - Honduras 4
JM - Giamaica 4
KH - Cambogia 4
KZ - Kazakistan 4
NO - Norvegia 4
OM - Oman 4
PA - Panama 4
PH - Filippine 4
PT - Portogallo 4
RS - Serbia 4
BY - Bielorussia 3
DZ - Algeria 3
HR - Croazia 3
MN - Mongolia 3
QA - Qatar 3
AM - Armenia 2
BB - Barbados 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
GY - Guiana 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
SV - El Salvador 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BO - Bolivia 1
ET - Etiopia 1
Totale 23.777
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Città #
Southend 1.897
Fairfield 1.111
Dublin 1.031
Dallas 971
Ashburn 815
Singapore 768
Chandler 545
Wilmington 481
Woodbridge 469
Houston 462
Jacksonville 441
Moscow 420
Seattle 417
Cambridge 401
Santa Clara 389
Beijing 387
Hong Kong 337
Ann Arbor 310
San Jose 294
Siena 276
Hefei 259
Seoul 223
Princeton 183
Nanjing 171
The Dalles 159
Ho Chi Minh City 137
Los Angeles 136
Helsinki 116
Council Bluffs 114
Lauterbourg 103
Boardman 95
Hanoi 85
New York 84
Fremont 81
Dong Ket 78
San Mateo 78
San Diego 73
Milan 71
Johannesburg 66
Izmir 64
São Paulo 63
Shanghai 60
Munich 58
Florence 57
Nanchang 54
London 53
Málaga 51
Columbus 49
Buffalo 48
Bengaluru 43
Tianjin 42
Dearborn 41
Menlo Park 40
Shenyang 39
Orem 37
Chicago 35
Redondo Beach 33
Hebei 29
Jinan 29
Brussels 28
San Francisco 28
Washington 27
Chennai 26
Guangzhou 26
Turku 26
Frankfurt am Main 25
Rome 24
Hangzhou 22
Zhengzhou 22
Atlanta 21
Rio de Janeiro 21
Abuja 20
Changsha 20
Jiaxing 20
Toronto 20
Belo Horizonte 19
Brno 19
Brooklyn 19
Lappeenranta 19
Montreal 19
Nuremberg 19
Tokyo 19
Vienna 19
Warsaw 19
Norwalk 18
Taizhou 18
Da Nang 17
Manchester 17
Poplar 17
Baghdad 16
Boston 16
Curitiba 15
Redwood City 15
Amsterdam 13
Mexico City 13
Mumbai 13
Stockholm 13
Canberra 12
Düsseldorf 12
Jakarta 12
Totale 16.243
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Nome #
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 397
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors 380
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 355
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 329
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 313
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 312
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 302
Resveratrol: from diet to topical usage 301
The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo. 289
Effects of aqueous extract of lycopersicum esculentum L. var. “Camone” tomato on blood pressure, behavior and brain susceptibility to oxidative stress in spontaneously hypertensive rats 288
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 284
Calcium and taurine interaction in mammalian brain metabolism 281
Effects of taurine and structurally related analogues on Ca2+ uptake and respiration rate in rat liver mitochondria 272
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 269
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields 264
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 263
Calcium channel antagonists discovered by a multidisciplinary approach 251
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 250
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 249
In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies 248
In vitro assessement of tariquidar toxicity towards vasculature 248
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 247
Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage 246
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 239
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors 239
Changes in CSF composition during heat stress and fever in conscious rabbits 237
Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein 235
Human tuberculosis I. epidemiology, diagnosis and pathogenetic mechanisms 233
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 231
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 230
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 229
3,5-di-t-butylcatechol (DTCAT) as an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC) 227
Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies 226
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 223
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 222
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 222
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 221
Antagonism by taurine on the ruthenium red-induced and 6-hydroxydopamine plus 1-methyl-4-phenylpyridinium-induced Ca2+ release from rat liver mitochondria 221
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 220
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies 220
Potentiation of mitochondrial Ca2+ sequestration by taurine 218
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects 217
The in vivo release of taurine in the striatonigral pathway 215
Apoptotic-induced Effects of Castanea sativa Bark Extract in Human SH-SY5Y Neuroblastoma Cells 214
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 212
Effect of the endocrine disruptor Bisphenol A in in vitro models of human placenta 211
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 210
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 210
Possible involvement of brain calcium metabolism in the action of taurine in mammalian thermoregulation 206
Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells 206
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 204
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 204
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 204
Calcium changes in rabbit CSF during endotoxin, IL-1 beta, and PGE2 fever 200
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 199
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker 198
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 198
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 198
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 197
Selective ozone concentrations may reduce the ischemic damage after a stroke 197
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 196
The mitochondrial permeability transition and taurine 195
Role of taurine in thermoregulation and motor control. Behavioural and cellular studies 192
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 192
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 192
Pharmacokinetic of diphenydramine in young volunteers with a dimenhydrinate 25 mg chewing gum formulation 191
Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines. 191
Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury 191
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 190
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 189
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 189
Effects of bacterial endotoxin, interleukin-1 and prostaglandins on thermoregulation and cerebrospinal fluid-calcium concentration in rabbits 189
Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents 188
Synthesis of taurine analogues from alkenes 188
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes 187
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 187
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 185
Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs 184
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 182
Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig 181
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 181
Neuroprotective Effects of Castanea sativa Mill. Bark Extract in Human Neuroblastoma Cells Subjected to Oxidative Stress 178
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 177
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives 177
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect 177
Apoptotic-induced effects of acacia catechu willd. Extract in human colon cancer cells 177
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From calcium-channel modulators properties to multidrug-resistance reverting activity 175
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 167
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA 166
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles 165
Playing with opening and closing of heterocycles: using the Cusmano-Ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors 164
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 164
Olive leaves and hibiscus flowers extracts-based preparation protect brain from oxidative stress-induced injury 162
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening 156
Effect of the endocrine distruptor Bisphenonol in "in vitro" models of human placenta 154
In vivo release of taurine from rat neostriatum and substantia nigra 154
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 153
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations 152
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme 146
Serum Metabolomics and Proteomics to Study the Antihypertensive Effect of Protein Extracts from Tenebrio molitor 144
Totale 21.699
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Categoria #
all - tutte 73.171
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.171
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021716 0 0 0 0 0 0 0 0 0 280 248 188
2021/20221.629 104 187 134 139 99 50 93 92 82 180 157 312
2022/20232.122 127 185 308 297 164 400 37 196 233 79 66 30
2023/20241.723 70 31 157 74 95 432 559 34 13 41 50 167
2024/20253.391 108 154 309 200 437 197 127 208 329 189 335 798
2025/20266.840 635 1.046 806 812 1.444 241 884 267 337 368 0 0
Totale 24.114