IRIS
FROSINI, MARIA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 6.824
EU - Europa 6.425
AS - Asia 1.187
SA - Sud America 17
AF - Africa 15
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 6
Totale 14.486
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 6.794
GB - Regno Unito 2.051
IE - Irlanda 1.041
CN - Cina 767
IT - Italia 692
SE - Svezia 591
UA - Ucraina 561
RU - Federazione Russa 446
DE - Germania 363
FR - Francia 290
SG - Singapore 212
FI - Finlandia 189
VN - Vietnam 81
TR - Turchia 69
ES - Italia 53
CZ - Repubblica Ceca 31
BE - Belgio 26
CA - Canada 25
IN - India 16
GR - Grecia 15
NL - Olanda 15
AU - Australia 12
BR - Brasile 10
CI - Costa d'Avorio 10
IR - Iran 10
RO - Romania 10
AT - Austria 9
HU - Ungheria 9
EU - Europa 6
CH - Svizzera 5
BG - Bulgaria 4
DK - Danimarca 4
MX - Messico 4
PK - Pakistan 4
AE - Emirati Arabi Uniti 3
AR - Argentina 3
EG - Egitto 3
KR - Corea 3
NO - Norvegia 3
SA - Arabia Saudita 3
AM - Armenia 2
BD - Bangladesh 2
CL - Cile 2
IL - Israele 2
JO - Giordania 2
LT - Lituania 2
LV - Lettonia 2
MD - Moldavia 2
MY - Malesia 2
PL - Polonia 2
RS - Serbia 2
AZ - Azerbaigian 1
CY - Cipro 1
EC - Ecuador 1
EE - Estonia 1
GH - Ghana 1
HK - Hong Kong 1
HR - Croazia 1
ID - Indonesia 1
IM - Isola di Man 1
JP - Giappone 1
KH - Cambogia 1
KZ - Kazakistan 1
LU - Lussemburgo 1
MK - Macedonia 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 14.486
Salva come PNG Salva come JPEG
Città #
Southend 1.897
Fairfield 1.111
Dublin 1.028
Ashburn 619
Chandler 545
Wilmington 479
Woodbridge 469
Houston 455
Jacksonville 439
Seattle 414
Cambridge 401
Ann Arbor 310
Siena 270
Princeton 183
Nanjing 171
Beijing 153
Singapore 142
Boardman 94
Helsinki 88
Fremont 81
Dong Ket 78
San Mateo 78
San Diego 73
Izmir 62
Moscow 55
Nanchang 54
New York 53
Málaga 51
Shanghai 51
Dearborn 41
Menlo Park 40
Shenyang 38
Tianjin 35
London 32
Florence 31
Milan 30
Hebei 29
Jinan 29
Brussels 26
Washington 25
Hangzhou 20
Jiaxing 20
San Francisco 20
Brno 18
Munich 18
Norwalk 18
Zhengzhou 18
Los Angeles 17
Taizhou 17
Redwood City 15
Lappeenranta 14
Changsha 13
Guangzhou 13
Rome 13
Düsseldorf 11
Kunming 11
Toronto 11
Abidjan 10
Chicago 10
Columbus 10
Mestre 10
Olomouc 10
Dallas 9
Latina 9
Ningbo 9
San Costantino Calabro 9
Tappahannock 9
Changchun 8
Hefei 8
Torino 8
Vienna 8
Auburn Hills 7
Berlin 7
Canberra 7
Falls Church 7
Naples 7
Nottingham 7
Venezia 7
Budapest 6
Lancaster 6
Zanjan 6
Amsterdam 5
Bari 5
Bologna 5
Candiolo 5
Cerreto Guidi 5
Galatone 5
Kilburn 5
Lamezia Terme 5
Lanzhou 5
Leawood 5
Scarperia 5
Acton 4
Ambrogio 4
Andover 4
Arconate 4
Edinburgh 4
Falkenstein 4
Frankfurt am Main 4
Horia 4
Totale 10.808
Salva come PNG Salva come JPEG
Nome #
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 283
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors 261
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 256
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 241
The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo. 225
Resveratrol: from diet to topical usage 213
Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage 196
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 189
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 187
Calcium and taurine interaction in mammalian brain metabolism 185
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 181
Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies 178
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 176
Effects of taurine and structurally related analogues on Ca2+ uptake and respiration rate in rat liver mitochondria 173
In vitro assessement of tariquidar toxicity towards vasculature 172
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields 169
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 168
Human tuberculosis I. epidemiology, diagnosis and pathogenetic mechanisms 166
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies 164
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors 164
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 163
In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies 161
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 159
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 158
Changes in CSF composition during heat stress and fever in conscious rabbits 158
The in vivo release of taurine in the striatonigral pathway 157
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 156
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 156
Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein 156
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects 155
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 155
Possible involvement of brain calcium metabolism in the action of taurine in mammalian thermoregulation 153
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 152
Calcium channel antagonists discovered by a multidisciplinary approach 150
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 149
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 148
Effects of aqueous extract of lycopersicum esculentum L. var. “Camone” tomato on blood pressure, behavior and brain susceptibility to oxidative stress in spontaneously hypertensive rats 144
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 143
Potentiation of mitochondrial Ca2+ sequestration by taurine 142
Synthesis of taurine analogues from alkenes 142
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 142
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 141
Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs 140
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 140
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 138
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 137
Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines. 136
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 136
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 136
Apoptotic-induced Effects of Castanea sativa Bark Extract in Human SH-SY5Y Neuroblastoma Cells 136
Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells 133
Selective ozone concentrations may reduce the ischemic damage after a stroke 132
Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury 131
The mitochondrial permeability transition and taurine 130
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 129
Neuroprotective Effects of Castanea sativa Mill. Bark Extract in Human Neuroblastoma Cells Subjected to Oxidative Stress 129
Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig 129
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 128
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 128
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 127
Antagonism by taurine on the ruthenium red-induced and 6-hydroxydopamine plus 1-methyl-4-phenylpyridinium-induced Ca2+ release from rat liver mitochondria 126
Role of taurine in thermoregulation and motor control. Behavioural and cellular studies 126
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 125
Effects of bacterial endotoxin, interleukin-1 and prostaglandins on thermoregulation and cerebrospinal fluid-calcium concentration in rabbits 125
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 125
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 125
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives 124
3,5-di-t-butylcatechol (DTCAT) as an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC) 121
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 119
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 119
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker 118
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect 118
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 113
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 111
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes 111
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations 111
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 111
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 110
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles 110
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA 109
Playing with opening and closing of heterocycles: using the Cusmano-Ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors. 109
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From calcium-channel modulators properties to multidrug-resistance reverting activity 108
null 106
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 105
In vivo release of taurine from rat neostriatum and substantia nigra 103
null 103
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 103
Effect of the endocrine disruptor Bisphenol A in in vitro models of human placenta 101
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening 97
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 96
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 96
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 95
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 94
Olive leaves and hibiscus flowers extracts-based preparation protect brain from oxidative stress-induced injury 93
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 91
Nitric oxide modulation of interleukin-1[beta]-evoked intracellular Ca2+ release in human astrocytoma U-373 MG cells and brain striatal slices. 90
Apoptotic-induced effects of acacia catechu willd. Extract in human colon cancer cells 90
Calcium changes in rabbit CSF during endotoxin, IL-1 beta, and PGE2 fever 88
Iron(III) complexing ability of new ligands based on natural γ-pyrone maltol 86
Effect of the endocrine distruptor Bisphenonol in "in vitro" models of human placenta 81
Totale 13.974
Salva come PNG Salva come JPEG
Categoria #
all - tutte 49.060
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.060
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.909 0 0 0 0 232 281 267 346 300 238 85 160
2020/20212.656 149 244 72 250 240 336 87 327 235 280 248 188
2021/20221.629 104 187 134 139 99 50 93 92 82 180 157 312
2022/20232.122 127 185 308 297 164 400 37 196 233 79 66 30
2023/20241.723 70 31 157 74 95 432 559 34 13 41 50 167
2024/2025897 108 154 309 200 126 0 0 0 0 0 0 0
Totale 14.780