IRIS
FROSINI, MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 9.196
EU - Europa 8.005
AS - Asia 3.767
SA - Sud America 711
AF - Africa 56
OC - Oceania 16
Continente sconosciuto - Info sul continente non disponibili 6
Totale 21.757
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Nazione #
US - Stati Uniti d'America 9.082
GB - Regno Unito 2.121
RU - Federazione Russa 1.561
CN - Cina 1.521
SG - Singapore 1.164
IE - Irlanda 1.042
IT - Italia 804
SE - Svezia 601
BR - Brasile 598
UA - Ucraina 573
DE - Germania 440
FR - Francia 324
HK - Hong Kong 283
KR - Corea 225
FI - Finlandia 220
VN - Vietnam 198
IN - India 98
TR - Turchia 93
ES - Italia 69
CA - Canada 60
AR - Argentina 58
NL - Olanda 35
MX - Messico 33
AT - Austria 32
CZ - Repubblica Ceca 32
BE - Belgio 28
BD - Bangladesh 25
PL - Polonia 21
IQ - Iraq 20
EC - Ecuador 19
JP - Giappone 18
IR - Iran 16
GR - Grecia 15
ID - Indonesia 15
ZA - Sudafrica 15
AU - Australia 14
BG - Bulgaria 14
MA - Marocco 12
PK - Pakistan 12
AE - Emirati Arabi Uniti 10
CI - Costa d'Avorio 10
RO - Romania 10
EG - Egitto 9
HU - Ungheria 9
JO - Giordania 8
LT - Lituania 8
SA - Arabia Saudita 8
CL - Cile 7
CO - Colombia 7
DK - Danimarca 7
EE - Estonia 7
NP - Nepal 7
PY - Paraguay 7
UZ - Uzbekistan 7
EU - Europa 6
PE - Perù 6
CH - Svizzera 5
IL - Israele 5
LB - Libano 5
LV - Lettonia 5
VE - Venezuela 5
JM - Giamaica 4
KE - Kenya 4
KH - Cambogia 4
PA - Panama 4
PT - Portogallo 4
CY - Cipro 3
HN - Honduras 3
HR - Croazia 3
KZ - Kazakistan 3
NO - Norvegia 3
RS - Serbia 3
TN - Tunisia 3
AM - Armenia 2
AZ - Azerbaigian 2
BB - Barbados 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
MY - Malesia 2
NZ - Nuova Zelanda 2
OM - Oman 2
PH - Filippine 2
SV - El Salvador 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BO - Bolivia 1
BY - Bielorussia 1
GE - Georgia 1
GH - Ghana 1
GY - Guiana 1
IM - Isola di Man 1
LI - Liechtenstein 1
LK - Sri Lanka 1
LU - Lussemburgo 1
Totale 21.752
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Città #
Southend 1.897
Fairfield 1.111
Dublin 1.029
Dallas 963
Ashburn 758
Singapore 655
Chandler 545
Wilmington 481
Woodbridge 469
Houston 462
Jacksonville 441
Moscow 419
Seattle 417
Cambridge 401
Beijing 386
Santa Clara 383
Ann Arbor 310
Hong Kong 282
Siena 276
Seoul 223
Hefei 210
Princeton 183
Nanjing 171
Los Angeles 107
Boardman 95
Helsinki 94
Fremont 81
New York 79
Dong Ket 78
San Mateo 78
The Dalles 78
San Diego 73
Izmir 64
São Paulo 59
Munich 58
Milan 56
Shanghai 56
Florence 55
Nanchang 54
Council Bluffs 53
Málaga 51
Columbus 48
Buffalo 47
Ho Chi Minh City 47
London 46
Bengaluru 43
Dearborn 41
Tianjin 41
Menlo Park 40
Shenyang 39
Redondo Beach 33
Chicago 31
Hebei 29
Jinan 29
Brussels 28
San Francisco 27
Turku 26
Hanoi 25
Washington 25
Hangzhou 21
Rio de Janeiro 21
Zhengzhou 21
Changsha 20
Guangzhou 20
Jiaxing 20
Toronto 20
Brooklyn 19
Rome 19
Vienna 19
Atlanta 18
Belo Horizonte 18
Brno 18
Norwalk 18
Nuremberg 18
Taizhou 18
Lappeenranta 17
Tokyo 16
Warsaw 16
Montreal 15
Poplar 15
Redwood City 15
Curitiba 14
Boston 13
Düsseldorf 12
Frankfurt am Main 12
Stockholm 12
Kunming 11
Manchester 11
Mexico City 11
Phoenix 11
Abidjan 10
Brasília 10
Johannesburg 10
Mestre 10
Olomouc 10
Orem 10
Baghdad 9
Bexley 9
Changchun 9
Chennai 9
Totale 14.991
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Nome #
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 364
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors 352
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 330
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 307
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 292
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 291
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 284
Resveratrol: from diet to topical usage 274
The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo. 266
Calcium and taurine interaction in mammalian brain metabolism 259
Effects of taurine and structurally related analogues on Ca2+ uptake and respiration rate in rat liver mitochondria 254
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 252
Effects of aqueous extract of lycopersicum esculentum L. var. “Camone” tomato on blood pressure, behavior and brain susceptibility to oxidative stress in spontaneously hypertensive rats 251
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 248
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 245
Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage 236
In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies 235
Calcium channel antagonists discovered by a multidisciplinary approach 234
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields 233
In vitro assessement of tariquidar toxicity towards vasculature 233
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 229
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors 229
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 224
Changes in CSF composition during heat stress and fever in conscious rabbits 224
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 222
Human tuberculosis I. epidemiology, diagnosis and pathogenetic mechanisms 220
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 218
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 215
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 215
3,5-di-t-butylcatechol (DTCAT) as an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC) 214
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 214
Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein 214
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 213
Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies 213
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 210
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 210
Antagonism by taurine on the ruthenium red-induced and 6-hydroxydopamine plus 1-methyl-4-phenylpyridinium-induced Ca2+ release from rat liver mitochondria 208
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 208
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 206
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies 205
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects 203
Apoptotic-induced Effects of Castanea sativa Bark Extract in Human SH-SY5Y Neuroblastoma Cells 202
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 200
The in vivo release of taurine in the striatonigral pathway 199
Potentiation of mitochondrial Ca2+ sequestration by taurine 198
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 195
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 194
Effect of the endocrine disruptor Bisphenol A in in vitro models of human placenta 192
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 192
Possible involvement of brain calcium metabolism in the action of taurine in mammalian thermoregulation 191
Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells 191
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker 189
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 188
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 188
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 187
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 187
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 187
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 187
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 186
Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines. 184
Selective ozone concentrations may reduce the ischemic damage after a stroke 184
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 182
Synthesis of taurine analogues from alkenes 180
Calcium changes in rabbit CSF during endotoxin, IL-1 beta, and PGE2 fever 180
Effects of bacterial endotoxin, interleukin-1 and prostaglandins on thermoregulation and cerebrospinal fluid-calcium concentration in rabbits 180
Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury 180
The mitochondrial permeability transition and taurine 179
Pharmacokinetic of diphenydramine in young volunteers with a dimenhydrinate 25 mg chewing gum formulation 179
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 179
Role of taurine in thermoregulation and motor control. Behavioural and cellular studies 178
Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs 178
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 178
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 176
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 175
Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig 175
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 172
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes 171
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives 170
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 168
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 168
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 167
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 166
Neuroprotective Effects of Castanea sativa Mill. Bark Extract in Human Neuroblastoma Cells Subjected to Oxidative Stress 165
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect 164
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 163
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From calcium-channel modulators properties to multidrug-resistance reverting activity 161
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA 158
Playing with opening and closing of heterocycles: using the Cusmano-Ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors 154
Apoptotic-induced effects of acacia catechu willd. Extract in human colon cancer cells 153
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles 151
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening 147
Olive leaves and hibiscus flowers extracts-based preparation protect brain from oxidative stress-induced injury 144
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 144
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations 143
Effect of the endocrine distruptor Bisphenonol in "in vitro" models of human placenta 142
In vivo release of taurine from rat neostriatum and substantia nigra 141
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 139
Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents 130
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme 128
In vitro and in silico analysis of the vascular effects of asymmetrical N,N-bis(alkanol)amine aryl esters, novel multidrug resistance-reverting agents 126
Totale 20.109
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Categoria #
all - tutte 69.030
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 69.030
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.701 0 0 0 0 0 336 87 327 235 280 248 188
2021/20221.629 104 187 134 139 99 50 93 92 82 180 157 312
2022/20232.122 127 185 308 297 164 400 37 196 233 79 66 30
2023/20241.723 70 31 157 74 95 432 559 34 13 41 50 167
2024/20253.391 108 154 309 200 437 197 127 208 329 189 335 798
2025/20264.788 635 1.046 806 812 1.444 45 0 0 0 0 0 0
Totale 22.062