IRIS
FROSINI, MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 11.821
EU - Europa 9.072
AS - Asia 4.791
SA - Sud America 850
Continente sconosciuto - Info sul continente non disponibili 344
AF - Africa 164
OC - Oceania 22
Totale 27.064
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Nazione #
US - Stati Uniti d'America 11.572
GB - Regno Unito 2.202
CN - Cina 1.686
RU - Federazione Russa 1.586
SG - Singapore 1.498
IT - Italia 1.493
IE - Irlanda 1.046
BR - Brasile 672
SE - Svezia 611
UA - Ucraina 582
DE - Germania 477
VN - Vietnam 455
FR - Francia 440
HK - Hong Kong 357
FI - Finlandia 244
KR - Corea 227
IN - India 141
CA - Canada 123
TR - Turchia 98
ES - Italia 77
ZA - Sudafrica 74
AR - Argentina 67
BD - Bangladesh 64
NL - Olanda 58
MX - Messico 45
IQ - Iraq 36
CZ - Repubblica Ceca 34
AT - Austria 33
CO - Colombia 31
EC - Ecuador 30
BE - Belgio 28
PL - Polonia 27
ID - Indonesia 26
JP - Giappone 24
PK - Pakistan 22
AU - Australia 20
NG - Nigeria 20
IL - Israele 19
CL - Cile 18
BG - Bulgaria 17
IR - Iran 17
GR - Grecia 16
CR - Costa Rica 15
LT - Lituania 14
SC - Seychelles 14
AE - Emirati Arabi Uniti 13
MA - Marocco 13
RO - Romania 13
EE - Estonia 12
JM - Giamaica 12
JO - Giordania 12
SA - Arabia Saudita 12
CI - Costa d'Avorio 11
VE - Venezuela 11
HU - Ungheria 10
KE - Kenya 10
MY - Malesia 10
SV - El Salvador 10
DK - Danimarca 9
EG - Egitto 9
NP - Nepal 9
PE - Perù 9
UZ - Uzbekistan 9
CH - Svizzera 8
GT - Guatemala 8
HN - Honduras 8
LB - Libano 7
PY - Paraguay 7
EU - Europa 6
LV - Lettonia 6
NI - Nicaragua 6
PH - Filippine 6
PT - Portogallo 6
AZ - Azerbaigian 5
KZ - Kazakistan 5
OM - Oman 5
TN - Tunisia 5
CY - Cipro 4
KH - Cambogia 4
NO - Norvegia 4
PA - Panama 4
RS - Serbia 4
TT - Trinidad e Tobago 4
AM - Armenia 3
BY - Bielorussia 3
CW - ???statistics.table.value.countryCode.CW??? 3
DZ - Algeria 3
HR - Croazia 3
MN - Mongolia 3
QA - Qatar 3
BB - Barbados 2
DO - Repubblica Dominicana 2
GD - Grenada 2
GP - Guadalupe 2
GY - Guiana 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
PR - Porto Rico 2
TH - Thailandia 2
Totale 26.703
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Città #
Southend 1.897
Ashburn 1.150
Fairfield 1.111
Dublin 1.032
Dallas 990
Singapore 782
San Jose 601
Chandler 545
Wilmington 482
Santa Clara 475
Woodbridge 472
Houston 466
Jacksonville 446
Seattle 421
Moscow 420
Milan 407
Cambridge 402
Beijing 392
Hong Kong 343
Ann Arbor 310
Council Bluffs 280
Siena 276
Hefei 259
Seoul 223
Princeton 184
Nanjing 171
Los Angeles 166
The Dalles 162
Ho Chi Minh City 137
Rome 123
Helsinki 116
New York 114
Boardman 110
Lauterbourg 103
Hanoi 87
Fremont 83
Dong Ket 78
San Mateo 78
Columbus 77
San Diego 74
Florence 69
Johannesburg 66
Izmir 64
São Paulo 64
Shanghai 61
Munich 58
Buffalo 56
London 55
Nanchang 54
Málaga 51
Chicago 46
Bengaluru 43
Tianjin 42
Dearborn 41
Menlo Park 40
Orem 40
North Bergen 39
Shenyang 39
San Francisco 35
Redondo Beach 33
Atlanta 31
Washington 31
Hebei 29
Jinan 29
Montreal 29
Brussels 28
Figino 28
Chennai 26
Frankfurt am Main 26
Guangzhou 26
Toronto 26
Turku 26
Hangzhou 24
Phoenix 24
Brooklyn 22
Zhengzhou 22
Boston 21
Changsha 21
Rio de Janeiro 21
Abuja 20
Jiaxing 20
Naples 20
Nuremberg 20
Vienna 20
Belo Horizonte 19
Brno 19
Lappeenranta 19
Tokyo 19
Turin 19
Warsaw 19
Da Nang 18
Norwalk 18
Taizhou 18
Manchester 17
Philadelphia 17
Poplar 17
Salt Lake City 17
Baghdad 16
Mexico City 16
Brasília 15
Totale 17.914
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Nome #
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 430
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors 408
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats 387
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 363
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 344
Chemical characterization and antihypertensive effects of locular gel and serum of Lycopersicum esculentum L. var. “Camone” tomato in spontaneously hypertensive rats 334
Resveratrol: from diet to topical usage 327
In vitro toxicity evaluation of lomefloxacin-loaded MCM-41 mesoporous silica nanoparticles 317
Effects of aqueous extract of lycopersicum esculentum L. var. “Camone” tomato on blood pressure, behavior and brain susceptibility to oxidative stress in spontaneously hypertensive rats 313
The effect of kainic acid and AMPA on the release of taurine and GABA from the rat substantia nigra in vivo 306
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system 300
Acacia catechu willd. Extract protects neuronal cells from oxidative stress-induced damage 300
Effects of taurine and structurally related analogues on Ca2+ uptake and respiration rate in rat liver mitochondria 298
Calcium and taurine interaction in mammalian brain metabolism 298
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters 291
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields 290
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation 278
In vitro assessement of tariquidar toxicity towards vasculature 272
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta 270
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors 270
Calcium channel antagonists discovered by a multidisciplinary approach 269
In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies 268
Potentiation of intracellular Ca2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage 267
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings 267
CYP-dependent metabolism of PF9601N, a new monoamine oxidase-B inhibitor, by C57BL/6 mouse and human liver microsomes 265
Human tuberculosis I. epidemiology, diagnosis and pathogenetic mechanisms 259
3,5-di-t-butylcatechol (DTCAT) as an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC) 257
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics 257
Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein 255
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol 253
Interactions of taurine and structurally related analogues with GABAergic system and taurine binding sites of rabbit brain 253
Effect of the endocrine disruptor Bisphenol A in in vitro models of human placenta 249
N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates 248
Changes in CSF composition during heat stress and fever in conscious rabbits 247
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 246
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 245
Inhibition of rabbit brain 4-aminobutyrate transaminase by some taurine analogues: a kinetic analysis 243
Antagonism by taurine on the ruthenium red-induced and 6-hydroxydopamine plus 1-methyl-4-phenylpyridinium-induced Ca2+ release from rat liver mitochondria 242
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects 241
Potentiation of mitochondrial Ca2+ sequestration by taurine 238
Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies 238
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies 238
Effects of taurine and some structurally related analogues on the central mechanism of thermoregulation: a structure-activity relationship study 238
The in vivo release of taurine in the striatonigral pathway 236
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses 235
Heat-stress-induced hyperthermia alters CSF osmolality and composition in conscious rabbits 232
Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents 231
Apoptotic-induced Effects of Castanea sativa Bark Extract in Human SH-SY5Y Neuroblastoma Cells 229
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 228
HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits 227
Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells 224
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 222
GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behaviour 222
Selective ozone concentrations may reduce the ischemic damage after a stroke 222
Calcium changes in rabbit CSF during endotoxin, IL-1 beta, and PGE2 fever 221
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes 221
Possible involvement of brain calcium metabolism in the action of taurine in mammalian thermoregulation 220
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 219
Pharmacokinetic of diphenydramine in young volunteers with a dimenhydrinate 25 mg chewing gum formulation 218
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 218
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 217
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage 217
Synthesis of taurine analogues from alkenes 215
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker 215
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 215
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 215
The mitochondrial permeability transition and taurine 214
Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury 214
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases 213
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells 213
l-Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes 212
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds 212
Role of intracellular Ca2+ and calmodulin/MAP kinase kinase/extracellular signal-regulated protein kinase signalling pathway in the mitogenic and antimitogenic effect of nitric oxide in glia- and neurone-derived cell lines 211
β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration 211
Effects of bacterial endotoxin, interleukin-1 and prostaglandins on thermoregulation and cerebrospinal fluid-calcium concentration in rabbits 207
Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices 205
Role of taurine in thermoregulation and motor control. Behavioural and cellular studies 204
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From calcium-channel modulators properties to multidrug-resistance reverting activity 203
Human tuberculosis II. m. tuberculosis mechanisms of genetic and phenotypic resistance to anti-tuberculosis drugs 200
Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig 200
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injectionof GABA, GABAA and GABAB agonists and antagonists 200
The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress 198
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids 198
Neuroprotection afforded by GABA against oxygen-glucose deprivation-induced injury in rat cortical brain slices: an hormetic dose-response effect 198
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives 196
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl 196
Apoptotic-induced effects of acacia catechu willd. Extract in human colon cancer cells 195
Neuroprotective Effects of Castanea sativa Mill. Bark Extract in Human Neuroblastoma Cells Subjected to Oxidative Stress 192
Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin 190
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles 190
Effect of the endocrine distruptor Bisphenonol in "in vitro" models of human placenta 189
Ligand promiscuity between the efflux pumps human p-glycoprotein and s. aureus NorA 185
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 179
Playing with opening and closing of heterocycles: using the Cusmano-Ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors 177
In vivo release of taurine from rat neostriatum and substantia nigra 175
Cytochrome P450-dependent metabolism of l-deprenyl in monkey (Cercopithecus aethiops) and C57BL/6 mouse brain microsomal preparations 175
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening 174
Olive leaves and hibiscus flowers extracts-based preparation protect brain from oxidative stress-induced injury 170
Serum Metabolomics and Proteomics to Study the Antihypertensive Effect of Protein Extracts from Tenebrio molitor 169
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme 168
Totale 23.931
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Categoria #
all - tutte 85.360
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 85.360
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.065 0 0 0 0 99 50 93 92 82 180 157 312
2022/20232.122 127 185 308 297 164 400 37 196 233 79 66 30
2023/20241.723 70 31 157 74 95 432 559 34 13 41 50 167
2024/20253.391 108 154 309 200 437 197 127 208 329 189 335 798
2025/20267.769 635 1.046 806 812 1.444 241 884 267 337 430 202 665
2026/20272.021 400 256 733 535 97 0 0 0 0 0 0 0
Totale 27.064