IRIS
CORELLI, FEDERICO
 Distribuzione geografica
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Continente #
NA - Nord America 15.706
EU - Europa 12.199
AS - Asia 7.115
SA - Sud America 1.254
AF - Africa 277
OC - Oceania 28
Continente sconosciuto - Info sul continente non disponibili 6
Totale 36.585
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Nazione #
US - Stati Uniti d'America 15.535
GB - Regno Unito 2.884
CN - Cina 2.556
SG - Singapore 2.150
RU - Federazione Russa 2.125
IE - Irlanda 1.621
IT - Italia 1.307
UA - Ucraina 1.043
BR - Brasile 1.039
FR - Francia 921
SE - Svezia 841
DE - Germania 710
VN - Vietnam 631
HK - Hong Kong 545
KR - Corea 427
FI - Finlandia 371
IN - India 220
TR - Turchia 115
ZA - Sudafrica 115
CA - Canada 84
AR - Argentina 73
BD - Bangladesh 71
JP - Giappone 68
ES - Italia 64
MX - Messico 60
IQ - Iraq 51
PL - Polonia 49
NL - Olanda 47
NG - Nigeria 39
EC - Ecuador 35
PK - Pakistan 35
CI - Costa d'Avorio 34
ID - Indonesia 32
BE - Belgio 31
CZ - Repubblica Ceca 28
AU - Australia 25
CL - Cile 25
SA - Arabia Saudita 25
AT - Austria 23
CO - Colombia 22
PY - Paraguay 19
UZ - Uzbekistan 19
VE - Venezuela 19
MA - Marocco 18
EG - Egitto 17
RO - Romania 17
AE - Emirati Arabi Uniti 16
JO - Giordania 16
KE - Kenya 16
MY - Malesia 14
CH - Svizzera 13
LT - Lituania 13
TW - Taiwan 12
AL - Albania 11
IL - Israele 11
TN - Tunisia 11
SN - Senegal 10
UY - Uruguay 10
EE - Estonia 9
KZ - Kazakistan 9
NP - Nepal 9
PH - Filippine 9
PT - Portogallo 9
GR - Grecia 8
IR - Iran 8
RS - Serbia 8
PE - Perù 7
TH - Thailandia 7
AZ - Azerbaigian 6
DK - Danimarca 6
GE - Georgia 6
SI - Slovenia 6
BG - Bulgaria 5
BH - Bahrain 5
CR - Costa Rica 5
HU - Ungheria 5
LB - Libano 5
LK - Sri Lanka 5
NO - Norvegia 5
AM - Armenia 4
DO - Repubblica Dominicana 4
DZ - Algeria 4
ET - Etiopia 4
EU - Europa 4
HN - Honduras 4
LV - Lettonia 4
OM - Oman 4
PS - Palestinian Territory 4
SY - Repubblica araba siriana 4
AO - Angola 3
HR - Croazia 3
IM - Isola di Man 3
KG - Kirghizistan 3
KW - Kuwait 3
MD - Moldavia 3
NZ - Nuova Zelanda 3
PA - Panama 3
SK - Slovacchia (Repubblica Slovacca) 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
Totale 36.554
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Città #
Southend 2.582
Dallas 2.160
Dublin 1.617
Fairfield 1.486
Menlo Park 1.451
Singapore 1.208
Ashburn 872
Jacksonville 844
Chandler 812
Woodbridge 711
Wilmington 637
Beijing 615
Santa Clara 605
Moscow 578
Houston 552
Hong Kong 520
Seattle 500
Cambridge 489
Hefei 452
Seoul 421
Siena 345
Ann Arbor 344
San Jose 328
The Dalles 299
Princeton 294
Nanjing 286
Ho Chi Minh City 217
Los Angeles 200
Lauterbourg 177
Helsinki 165
Boardman 148
Hanoi 144
Nanchang 124
New York 114
Buffalo 107
Milan 104
Florence 96
San Diego 96
Johannesburg 95
San Mateo 91
Council Bluffs 90
São Paulo 89
Fremont 86
Bengaluru 67
Shenyang 67
Tianjin 62
Izmir 61
Munich 59
London 58
Shanghai 57
Rome 53
Hebei 52
Tokyo 52
Düsseldorf 49
Orem 46
Frankfurt am Main 43
Dearborn 41
Changsha 40
Columbus 40
Norwalk 40
Venezia 40
Rio de Janeiro 39
Chennai 36
Abidjan 34
Abuja 34
Chicago 34
Guangzhou 33
Kunming 32
San Francisco 32
Haiphong 31
Jiaxing 31
Turku 30
Lancaster 29
Brussels 28
Mumbai 28
Redondo Beach 28
Warsaw 28
Atlanta 25
Redwood City 24
Hangzhou 23
Stockholm 23
Belo Horizonte 22
Brooklyn 22
Da Nang 22
Jinan 22
Montreal 22
Málaga 22
Zhengzhou 22
Anguillara Sabazia 20
Naples 19
Ningbo 19
Baghdad 18
Campinas 18
Curitiba 18
Washington 18
Biên Hòa 17
Guarulhos 17
Manchester 17
Amman 16
Amsterdam 16
Totale 25.047
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Nome #
Ligandi TRPV1 480
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 397
1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 and CB2 receptor ligands 354
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor 316
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 311
Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease 300
Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach 296
Synthesis of pyrazolo[1,5-a]pyrimidine ring as a possible bioisosteric replacement of the 5-(1H-pyrrol-1-yl)pyrazole scaffold 285
Computational studies of competitive inhibitors of nitric oxide synthase (NOS) enzymes: towards the development of powerful and isoform-selective inhibitors 274
Design, Synthesis, and Pharmacological Characterization of Indole-3-ylacetamides, Indole-3-yloxoacetamides, and Indole-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse Agonists 274
Activation of the GABAB receptor prevents nicotine-induced locomotor stimulation in mice 272
New fluoroquinolones active against fluoroquinolones-resistant Mycobacterium tuberculosis strains 272
Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors 269
6-Vinyl pyrimidine and pyrimidinone derivatives and the use thereof 268
3D QSAR studies of the interaction between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA). A combined pharmacophore generation and pseudoreceptor modeling approach applied to taxanes and epothilones 266
A Novel Route to Calix[4]arenes. 2. Solution- and Solid-State Structural Analyses and Molecular Modeling Studies 258
6-Substituted-4(3H)-pyrimidinones. A family of antiviral agents possessing a broad spectrum of activities 253
Suppressing effect of COR659 on alcohol, sucrose, and chocolate self-administration in rats: Involvement of the GABAB and cannabinoid CB1 receptors 252
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility 250
Synthesis, 1 structural properties, and pharmacological evaluation of 2-(acylamino)thiophene-3-carboxamides and analogues thereof 247
A combinatorial approach for the solid phase synthesis of 5,6-disubstituted pyrimidinones and pyrimidine derivatives 246
3D QSAR models of interaction between b-tubulin and MSAAs: taxanes and epothilones 246
A new linker for anchoring/masking primary amines on solid support 246
A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors 245
Anxiety-like behaviors at the end of the nocturnal period in sP rats with a “history” of unpredictable, limited access to alcohol. 243
NUOVA TERAPIA PER IL TRATTAMENTO DELL'IPERURICEMIA NELLA SINDROME DI LESCH-NYHAN 243
Screen of unfocused libraries identified compounds with direct or synergistic antibacterial activity 242
Synthesis and biological evaluation of New N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands 241
Antifungal agents. 10. New derivatives of 1-[(Aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, synthesis, anti-Candida activity and Quantitative Structure-Analysis Relationship studies 240
An improved synthesis of solid-supported reagents (SSRs) for selective acylation of amines by microwave irradiation 239
3D QSAR studies for the β-tubulin binding site of microtubule-stabilizing anticancer agents (MSAAs): A pseudoreceptor model for taxanes based on the experimental structure of tubulin 239
A genetic-function-approximation-based QSAR model for the affinity of arylpiperazines toward a1 adrenoceptors 238
Regioselective functionalization of quinolin-4(1H)-ones via sequential palladium-catalyzed reactions 237
Dihydro-alkylthio-benzyl-oxopyrimidines as Inhibitors of Reverse Transcriptase: Synthesis and Rationalization of the Biological Data on Both Wild-Type Enzyme and Relevant Clinical Mutants 237
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 3. Synthesis, Structure-Affinity Relationships, and Pharmacological Characterization of 6-Substituted 4-Quinolone-3-carboxamides as Highly Selective Cannabinoid-2 Receptor Ligands 235
Combinatorial chemistry as a tool for targeting different stages of the replicative HIV-1 cycle 235
Alpha1-Adrenoceptor Antagonists. 4. Pharmacophore-based Design, Synthesis, and Biological Evaluation of New Imidazo-, Benzimidazo-, and Indoloarylpiperazine Derivatives 234
Simplified Analogues of Immucillin-G Retain Potent Human Purine Nucleoside Phosphorylase Inhibitory Activity 234
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 1. Synthesis and Structure-Activity Relationship of a Class of Human Immunodeficiency Virus type 1 Integrase Inhibitors 234
Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor 233
6-Substituted-4(3H)-pyrimidinones. A family of antiviral agents possessing a broad spectrum of activities 233
Chiral Azole Derivatives, 3. Synthesis of the Enantiomers of the Potent Aromatase Inhibitor 1-[2-Benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole 231
A pharmacophore modeling approach to design new taxol® mimics: towards the synthesis of potential anticancer and MDR-reversing agent 229
Parallel solution phase synthesis of 4-dialkylamino-2-methylsulfonyl-6-vinylpyrimidines 228
Design, synthesis, and physicochemical and pharmacological profiling of 7‐Hydroxy-5-oxopyrazolo[4,3‐b]pyridine-6-carboxamide derivatives with antiosteoarthritic activity in vivo 228
New Resorcinol-Anandamide "Hybrids" as Potent Cannabinoid Receptor Ligands Endowed with antinociceptive activity in vivo 225
A novel highly selective cannabinoid CB2 agonist reduces in vitro growth and TGF-beta release of human glial cell tumors 225
In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB2 receptor inverse agonists 224
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 6. Synthesis and Pharmacological Evaluation of 7-Substituted 4-Quinolone-3-carboxamide Derivatives as High Affinity Ligands for Cannabinoid Receptors 224
Synthesis of an original oxygenated taxuspine X analogue: a versatile non-natural natural product with remarkable P-gp modulating activity 224
3D QSAR models of interactions between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA): a survey on taxanes and epothilones 224
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 223
Antifungal Agents. 11.N-Substituted Derivatives of 1-[(Aryl)(4-aryl-1H-pyrrol-3yl)methyl]-1H-imidazole: Synthesis, Anti-Candida Activity, and QSAR Studies 221
Solid phase synthesis of 5,6-disubstituted pyrimidinone and pyrimidindione derivatives 221
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 2. Synthesis and Structure-Activity Relationship of Potent and Selective Cannabinoid-2 Receptor Agonists Endowed with Analgesic Activity in Vivo 220
Microwave-enhanced Sonogashira coupling reaction of substituted pyrimidinones and pyrimidine nucleosides 220
5,6-Dihydro-5-[4-[4-(2-methoxyphenyl)-1- piperazinyl]butyl]-4H- pyrrolo[1,2-a][1,4]benzodiazepine-4,6-dione and Related Compounds as New 5-HT1A Receptor Ligands 217
Reduction by the positive allosteric modulator of the GABAB receptor, GS39783, of alcohol self-administration in Sardinian alcohol-preferring rats exposed to the “sipper” procedure 215
Diltiazem-like calcium entry blockers: a hypothesis of the receptor-binding site based on a comparative molecular field analysis model 215
Microwave-assisted ethylene-alkyne cross-metathesis: synthesis of chiral 2-(N-1-acetyl-1-arylmethyl)-1,3-butadienes 213
Synthesis, Cannabinoid Receptor Affinity, and Molecular Modeling Studies of Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides 212
Solution-phase parallel synthesis of S-DABO analogues 212
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 209
Synthesis and Interaction with Copper(II) Cations of Cyano- and Aminoresorcin[4]arenes 209
Pyrrolobenzodiazepines and related systems. 2. Synthesis and biological properties of isonoraptazepine derivatives 205
Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies 205
Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands 205
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 204
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 204
COR758, a negative allosteric modulator of GABAB receptors 204
Solid-phase synthesis (SPS) of substituted uracils via Oxone® cleavage methodology 203
Chiral Azole Derivatives. 4. Enantiomers of Bifonazole and Related Antifungal Agents: Stereoselective Synthesis, Configuration Assignment, and Biological Evaluation 201
Efficient synthesis of iminoctadine, a potent antifungal agent and polyamine oxidase inhibitor (PAO) 200
Three-Dimensional Quantitative Structure-Selectivity Relationships (3D-QSSR) Analysis Guided Rational Design of a Highly Selective Ligand for the Cannabinoid Receptor 2 199
A model for the interaction of the sulfonic distamycin A derivatives, angiogenesis-modulating agents, with recombinant human basic fibroblast growth factor (bFGF) 199
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 198
Reducing effect of saikosaponin A, an active ingredient of Bupleurum falcatum, on alcohol self-administration in rats: Possible involvement of the GABAB receptor 197
Comparison of the effect of the positive allosteric modulator of the GABAb receptor, GS39783, on alcohol self-administration in three different lines of alcohol-preferring rats 197
Anti-addictive properties of COR659 – Additional pharmacological evidence and comparison with a series of novel analogues 196
Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors 194
Inhibition of alcohol self-administration by positive allosteric modulators of the GABA(B) receptor in rats: lack of tolerance and potentiation of baclofen 192
Synthesis, molecular modeling studies, and pharmacological activity of selective A1 receptor antagonists 190
Fibroblast growth factors and their inhibitors 187
Rational design and synthesis of homochiral azole antifungal agents 187
Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist 187
null 186
Preparation of a set of 4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-4-ones as potential Hsp90 ligands 185
Synthesis and biological evaluation of conformationally restricted analogs of tolmetin and ketorolac 185
Probing the substrate specificity for lipases. II. Kinetic and Modeling Studies on the Molecular Recognition of 2-Arylpropionic Esters by Candida rugosa and Rhizomucor miehei Lipases 185
Novel Substituted Aminoalkylguanidines as Potential Antihyperglycemic and Food Intake-Reducing Agents 184
New solid-supported reagents (SSRs) for selective acylation of amines 183
Practical synthesis of novel purine analogues as Hsp90 inhibitors. 183
Synthesis of reactive cytidine derivatives as building blocks for cross-linking oligonucleotides 183
Stereoselective synthesis of advanced intermediates en route to Taxuspine U and X: a study of macrocyclization via ring closing metathesis to highly constrained twelve-membered rings 183
Stereoselective synthesis of α-aryl-2-benzofuranmethanamines and α-aryl-1H-indole-2-methanamines through palladium-mediated annulation of chiral α-arylpropargylamines 181
Pharmacophore Based Receptor Modeling: The Case of Adenosine A3 Receptor Antagonists. An Approach to the Optimization of Protein Models 180
The 4-Quinolone-3-carboxylic Acid Motif as a Multivalent Scaffold in Medicinal Chemistry 180
Studies toward Taxuspine X, a potent Multidrug - Resistance Reversing Agent, via ring closing metathesis strategy 180
The tetramerization of 2,4-dimethoxycinnamates. A novel route to calixarenes 178
Towards new methodologies for the synthesis of biologically interesting 6-substituted pyrimidines and 4(3H)-pyrimidinones 178
Totale 22.871
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Categoria #
all - tutte 108.971
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 108.971
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021788 0 0 0 0 0 0 0 0 0 316 294 178
2021/20222.256 172 332 146 217 59 71 133 81 84 262 206 493
2022/20233.377 224 225 467 486 327 710 71 277 350 67 106 67
2023/20242.402 126 41 167 143 89 582 850 73 13 42 38 238
2024/20254.915 95 291 459 280 545 261 132 298 427 261 484 1.382
2025/202610.566 974 2.348 1.296 1.204 1.909 431 1.173 361 394 476 0 0
Totale 36.811