IRIS
CORELLI, FEDERICO
 Distribuzione geografica
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Continente #
NA - Nord America 16.074
EU - Europa 12.277
AS - Asia 7.293
SA - Sud America 1.255
AF - Africa 278
OC - Oceania 28
Continente sconosciuto - Info sul continente non disponibili 6
Totale 37.211
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Nazione #
US - Stati Uniti d'America 15.872
GB - Regno Unito 2.884
CN - Cina 2.591
SG - Singapore 2.180
RU - Federazione Russa 2.125
IE - Irlanda 1.621
IT - Italia 1.383
UA - Ucraina 1.043
BR - Brasile 1.040
FR - Francia 921
SE - Svezia 841
DE - Germania 710
VN - Vietnam 636
HK - Hong Kong 558
KR - Corea 428
FI - Finlandia 371
IN - India 220
BD - Bangladesh 161
TR - Turchia 115
ZA - Sudafrica 115
CA - Canada 96
AR - Argentina 73
MX - Messico 70
JP - Giappone 69
ES - Italia 65
IQ - Iraq 51
PL - Polonia 49
NL - Olanda 47
NG - Nigeria 39
PK - Pakistan 36
EC - Ecuador 35
CI - Costa d'Avorio 34
ID - Indonesia 33
BE - Belgio 31
CZ - Repubblica Ceca 28
AU - Australia 25
CL - Cile 25
SA - Arabia Saudita 25
AT - Austria 23
CO - Colombia 22
PY - Paraguay 19
UZ - Uzbekistan 19
VE - Venezuela 19
MA - Marocco 18
EG - Egitto 17
RO - Romania 17
AE - Emirati Arabi Uniti 16
JO - Giordania 16
KE - Kenya 16
MY - Malesia 15
LT - Lituania 14
CH - Svizzera 13
TN - Tunisia 12
TW - Taiwan 12
AL - Albania 11
IL - Israele 11
SN - Senegal 10
UY - Uruguay 10
EE - Estonia 9
KZ - Kazakistan 9
NP - Nepal 9
PH - Filippine 9
PT - Portogallo 9
GR - Grecia 8
IR - Iran 8
RS - Serbia 8
CR - Costa Rica 7
PE - Perù 7
TH - Thailandia 7
AZ - Azerbaigian 6
DK - Danimarca 6
GE - Georgia 6
SI - Slovenia 6
BG - Bulgaria 5
BH - Bahrain 5
HN - Honduras 5
HU - Ungheria 5
LB - Libano 5
LK - Sri Lanka 5
NO - Norvegia 5
TT - Trinidad e Tobago 5
AM - Armenia 4
DO - Repubblica Dominicana 4
DZ - Algeria 4
ET - Etiopia 4
EU - Europa 4
JM - Giamaica 4
LV - Lettonia 4
OM - Oman 4
PS - Palestinian Territory 4
SY - Repubblica araba siriana 4
AO - Angola 3
HR - Croazia 3
IM - Isola di Man 3
KG - Kirghizistan 3
KW - Kuwait 3
MD - Moldavia 3
NZ - Nuova Zelanda 3
PA - Panama 3
SK - Slovacchia (Repubblica Slovacca) 3
Totale 37.177
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Città #
Southend 2.582
Dallas 2.167
Dublin 1.618
Fairfield 1.486
Menlo Park 1.451
Singapore 1.215
Ashburn 898
Jacksonville 844
Chandler 813
Woodbridge 711
Wilmington 637
Santa Clara 631
Beijing 620
Moscow 578
Houston 553
Hong Kong 533
Seattle 500
Cambridge 489
Hefei 452
San Jose 421
Seoul 421
Siena 345
Ann Arbor 344
The Dalles 299
Princeton 294
Nanjing 287
Ho Chi Minh City 219
Los Angeles 210
Lauterbourg 177
Helsinki 165
Boardman 148
Hanoi 145
New York 131
Nanchang 124
Milan 117
Buffalo 112
Florence 99
San Diego 96
Johannesburg 95
Council Bluffs 92
San Mateo 91
São Paulo 89
Fremont 86
Bengaluru 67
Shenyang 67
Tianjin 62
Izmir 61
Rome 60
Munich 59
Shanghai 59
London 58
Hebei 52
Tokyo 52
Düsseldorf 49
Orem 48
Changsha 43
Frankfurt am Main 43
Columbus 41
Dearborn 41
Norwalk 40
Venezia 40
Rio de Janeiro 39
Chicago 37
Chennai 36
Abidjan 34
Abuja 34
Guangzhou 34
San Francisco 33
Kunming 32
Haiphong 31
Jiaxing 31
Turku 30
Lancaster 29
Brussels 28
Mumbai 28
Redondo Beach 28
Warsaw 28
Atlanta 26
Brooklyn 24
Hangzhou 24
Redwood City 24
Montreal 23
Stockholm 23
Belo Horizonte 22
Da Nang 22
Jinan 22
Málaga 22
Zhengzhou 22
Mexico City 21
Naples 21
Anguillara Sabazia 20
Ningbo 19
Baghdad 18
Campinas 18
Curitiba 18
Washington 18
Biên Hòa 17
Guarulhos 17
Manchester 17
Paris 17
Totale 25.314
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Nome #
Ligandi TRPV1 496
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 401
1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 and CB2 receptor ligands 359
Synthesis of pyrazolo[1,5-a]pyrimidine ring as a possible bioisosteric replacement of the 5-(1H-pyrrol-1-yl)pyrazole scaffold 355
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor 317
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury 314
Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease 307
Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach 298
Computational studies of competitive inhibitors of nitric oxide synthase (NOS) enzymes: towards the development of powerful and isoform-selective inhibitors 278
Design, Synthesis, and Pharmacological Characterization of Indole-3-ylacetamides, Indole-3-yloxoacetamides, and Indole-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse Agonists 277
New fluoroquinolones active against fluoroquinolones-resistant Mycobacterium tuberculosis strains 275
Activation of the GABAB receptor prevents nicotine-induced locomotor stimulation in mice 274
3D QSAR studies of the interaction between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA). A combined pharmacophore generation and pseudoreceptor modeling approach applied to taxanes and epothilones 271
Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors 270
6-Vinyl pyrimidine and pyrimidinone derivatives and the use thereof 270
A Novel Route to Calix[4]arenes. 2. Solution- and Solid-State Structural Analyses and Molecular Modeling Studies 261
6-Substituted-4(3H)-pyrimidinones. A family of antiviral agents possessing a broad spectrum of activities 257
Suppressing effect of COR659 on alcohol, sucrose, and chocolate self-administration in rats: Involvement of the GABAB and cannabinoid CB1 receptors 254
Synthesis, 1 structural properties, and pharmacological evaluation of 2-(acylamino)thiophene-3-carboxamides and analogues thereof 251
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility 251
A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors 249
3D QSAR models of interaction between b-tubulin and MSAAs: taxanes and epothilones 248
A combinatorial approach for the solid phase synthesis of 5,6-disubstituted pyrimidinones and pyrimidine derivatives 247
A new linker for anchoring/masking primary amines on solid support 247
Dihydro-alkylthio-benzyl-oxopyrimidines as Inhibitors of Reverse Transcriptase: Synthesis and Rationalization of the Biological Data on Both Wild-Type Enzyme and Relevant Clinical Mutants 245
NUOVA TERAPIA PER IL TRATTAMENTO DELL'IPERURICEMIA NELLA SINDROME DI LESCH-NYHAN 245
Screen of unfocused libraries identified compounds with direct or synergistic antibacterial activity 245
Synthesis and biological evaluation of New N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands 244
Anxiety-like behaviors at the end of the nocturnal period in sP rats with a “history” of unpredictable, limited access to alcohol. 243
A genetic-function-approximation-based QSAR model for the affinity of arylpiperazines toward a1 adrenoceptors 243
Antifungal agents. 10. New derivatives of 1-[(Aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, synthesis, anti-Candida activity and Quantitative Structure-Analysis Relationship studies 243
An improved synthesis of solid-supported reagents (SSRs) for selective acylation of amines by microwave irradiation 242
3D QSAR studies for the β-tubulin binding site of microtubule-stabilizing anticancer agents (MSAAs): A pseudoreceptor model for taxanes based on the experimental structure of tubulin 240
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 3. Synthesis, Structure-Affinity Relationships, and Pharmacological Characterization of 6-Substituted 4-Quinolone-3-carboxamides as Highly Selective Cannabinoid-2 Receptor Ligands 239
Regioselective functionalization of quinolin-4(1H)-ones via sequential palladium-catalyzed reactions 239
Alpha1-Adrenoceptor Antagonists. 4. Pharmacophore-based Design, Synthesis, and Biological Evaluation of New Imidazo-, Benzimidazo-, and Indoloarylpiperazine Derivatives 236
Combinatorial chemistry as a tool for targeting different stages of the replicative HIV-1 cycle 236
Simplified Analogues of Immucillin-G Retain Potent Human Purine Nucleoside Phosphorylase Inhibitory Activity 235
Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor 235
6-Substituted-4(3H)-pyrimidinones. A family of antiviral agents possessing a broad spectrum of activities 235
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 1. Synthesis and Structure-Activity Relationship of a Class of Human Immunodeficiency Virus type 1 Integrase Inhibitors 235
Chiral Azole Derivatives, 3. Synthesis of the Enantiomers of the Potent Aromatase Inhibitor 1-[2-Benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole 234
Parallel solution phase synthesis of 4-dialkylamino-2-methylsulfonyl-6-vinylpyrimidines 232
Design, synthesis, and physicochemical and pharmacological profiling of 7‐Hydroxy-5-oxopyrazolo[4,3‐b]pyridine-6-carboxamide derivatives with antiosteoarthritic activity in vivo 232
New Resorcinol-Anandamide "Hybrids" as Potent Cannabinoid Receptor Ligands Endowed with antinociceptive activity in vivo 231
A pharmacophore modeling approach to design new taxol® mimics: towards the synthesis of potential anticancer and MDR-reversing agent 231
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 6. Synthesis and Pharmacological Evaluation of 7-Substituted 4-Quinolone-3-carboxamide Derivatives as High Affinity Ligands for Cannabinoid Receptors 228
3D QSAR models of interactions between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA): a survey on taxanes and epothilones 228
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice 228
Synthesis of an original oxygenated taxuspine X analogue: a versatile non-natural natural product with remarkable P-gp modulating activity 227
A novel highly selective cannabinoid CB2 agonist reduces in vitro growth and TGF-beta release of human glial cell tumors 227
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 2. Synthesis and Structure-Activity Relationship of Potent and Selective Cannabinoid-2 Receptor Agonists Endowed with Analgesic Activity in Vivo 226
In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB2 receptor inverse agonists 225
Microwave-enhanced Sonogashira coupling reaction of substituted pyrimidinones and pyrimidine nucleosides 222
Antifungal Agents. 11.N-Substituted Derivatives of 1-[(Aryl)(4-aryl-1H-pyrrol-3yl)methyl]-1H-imidazole: Synthesis, Anti-Candida Activity, and QSAR Studies 221
Solid phase synthesis of 5,6-disubstituted pyrimidinone and pyrimidindione derivatives 221
Diltiazem-like calcium entry blockers: a hypothesis of the receptor-binding site based on a comparative molecular field analysis model 219
Reduction by the positive allosteric modulator of the GABAB receptor, GS39783, of alcohol self-administration in Sardinian alcohol-preferring rats exposed to the “sipper” procedure 217
Microwave-assisted ethylene-alkyne cross-metathesis: synthesis of chiral 2-(N-1-acetyl-1-arylmethyl)-1,3-butadienes 217
5,6-Dihydro-5-[4-[4-(2-methoxyphenyl)-1- piperazinyl]butyl]-4H- pyrrolo[1,2-a][1,4]benzodiazepine-4,6-dione and Related Compounds as New 5-HT1A Receptor Ligands 217
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 214
Solution-phase parallel synthesis of S-DABO analogues 214
Synthesis, Cannabinoid Receptor Affinity, and Molecular Modeling Studies of Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides 212
Synthesis and Interaction with Copper(II) Cations of Cyano- and Aminoresorcin[4]arenes 210
COR758, a negative allosteric modulator of GABAB receptors 210
Pyrrolobenzodiazepines and related systems. 2. Synthesis and biological properties of isonoraptazepine derivatives 208
Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies 208
Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands 208
Light-mediated activation/deactivation control and in vitro ADME-Tox profiling of a donepezil-like Dual AChE/MAO-B Inhibitor 204
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 204
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy 204
Solid-phase synthesis (SPS) of substituted uracils via Oxone® cleavage methodology 203
Chiral Azole Derivatives. 4. Enantiomers of Bifonazole and Related Antifungal Agents: Stereoselective Synthesis, Configuration Assignment, and Biological Evaluation 202
Anti-addictive properties of COR659 – Additional pharmacological evidence and comparison with a series of novel analogues 202
Three-Dimensional Quantitative Structure-Selectivity Relationships (3D-QSSR) Analysis Guided Rational Design of a Highly Selective Ligand for the Cannabinoid Receptor 2 201
A model for the interaction of the sulfonic distamycin A derivatives, angiogenesis-modulating agents, with recombinant human basic fibroblast growth factor (bFGF) 201
Efficient synthesis of iminoctadine, a potent antifungal agent and polyamine oxidase inhibitor (PAO) 201
The 4-Quinolone-3-carboxylic Acid Motif as a Multivalent Scaffold in Medicinal Chemistry 199
Synthesis, molecular modeling studies, and pharmacological activity of selective A1 receptor antagonists 199
Reducing effect of saikosaponin A, an active ingredient of Bupleurum falcatum, on alcohol self-administration in rats: Possible involvement of the GABAB receptor 198
Comparison of the effect of the positive allosteric modulator of the GABAb receptor, GS39783, on alcohol self-administration in three different lines of alcohol-preferring rats 198
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 198
Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors 194
Inhibition of alcohol self-administration by positive allosteric modulators of the GABA(B) receptor in rats: lack of tolerance and potentiation of baclofen 192
Fibroblast growth factors and their inhibitors 189
Rational design and synthesis of homochiral azole antifungal agents 189
Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist 189
Preparation of a set of 4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-4-ones as potential Hsp90 ligands 187
Practical synthesis of novel purine analogues as Hsp90 inhibitors. 187
Novel Substituted Aminoalkylguanidines as Potential Antihyperglycemic and Food Intake-Reducing Agents 186
Synthesis and biological evaluation of conformationally restricted analogs of tolmetin and ketorolac 186
null 186
Probing the substrate specificity for lipases. II. Kinetic and Modeling Studies on the Molecular Recognition of 2-Arylpropionic Esters by Candida rugosa and Rhizomucor miehei Lipases 186
New solid-supported reagents (SSRs) for selective acylation of amines 185
Stereoselective synthesis of advanced intermediates en route to Taxuspine U and X: a study of macrocyclization via ring closing metathesis to highly constrained twelve-membered rings 185
Synthesis of reactive cytidine derivatives as building blocks for cross-linking oligonucleotides 183
Molecular modeling of azole antifungal agents active against Candida albicans .1. A comparative molecular field analysis study 183
Stereoselective synthesis of α-aryl-2-benzofuranmethanamines and α-aryl-1H-indole-2-methanamines through palladium-mediated annulation of chiral α-arylpropargylamines 182
Characterization and Differentiation of Heterocyclic Isomers. Part 2. Mass Spectrometry and Molecular Orbital Calculations on Pyrrolo[1,2-a][1,4]benzodiazepin-4-one, -6-one, -4,6-dione 182
Parallel Solution-Phase and Microwave-Assisted Synthesis of New S-DABO Derivatives Endowed with Subnanomolar Anti-HIV-1 Activity 181
Totale 23.240
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Categoria #
all - tutte 113.426
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 113.426
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021178 0 0 0 0 0 0 0 0 0 0 0 178
2021/20222.256 172 332 146 217 59 71 133 81 84 262 206 493
2022/20233.377 224 225 467 486 327 710 71 277 350 67 106 67
2023/20242.402 126 41 167 143 89 582 850 73 13 42 38 238
2024/20254.915 95 291 459 280 545 261 132 298 427 261 484 1.382
2025/202611.196 974 2.348 1.296 1.204 1.909 431 1.173 361 394 576 310 220
Totale 37.441