Iminoctadine (1,17-diguanidino-9-azaheptadecane), isolated from a mixture of polyamines and guanidines known as guazatine that is used in agriculture as a fungicide, showed interesting activity as human antifungal agent and PAO inhibitor. In this paper, we propose a straightforward synthetic strategy for obtaining pure iminoctadine tris(trifluoroacetate) in high overall yield. © Georg Thieme Verlag Stuttgart.
Raffi, F., Corelli, F., Botta, M. (2007). Efficient synthesis of iminoctadine, a potent antifungal agent and polyamine oxidase inhibitor (PAO). SYNTHESIS, 19, 3013-3016 [10.1055/s-2007-983898].
Efficient synthesis of iminoctadine, a potent antifungal agent and polyamine oxidase inhibitor (PAO)
Raffi, Francesco;Corelli, Federico;Botta, Maurizio
2007-01-01
Abstract
Iminoctadine (1,17-diguanidino-9-azaheptadecane), isolated from a mixture of polyamines and guanidines known as guazatine that is used in agriculture as a fungicide, showed interesting activity as human antifungal agent and PAO inhibitor. In this paper, we propose a straightforward synthetic strategy for obtaining pure iminoctadine tris(trifluoroacetate) in high overall yield. © Georg Thieme Verlag Stuttgart.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/2543
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo