PINI, ALESSANDRO
 Distribuzione geografica
Continente #
NA - Nord America 5.888
EU - Europa 5.868
AS - Asia 891
SA - Sud America 15
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 11
AF - Africa 3
Totale 12.688
Nazione #
US - Stati Uniti d'America 5.870
GB - Regno Unito 1.863
IT - Italia 997
IE - Irlanda 986
CN - Cina 682
SE - Svezia 597
UA - Ucraina 524
DE - Germania 336
FR - Francia 259
FI - Finlandia 125
VN - Vietnam 91
ES - Italia 67
BE - Belgio 36
PL - Polonia 23
IR - Iran 22
TR - Turchia 22
CA - Canada 16
HK - Hong Kong 14
IN - India 13
NL - Olanda 13
EU - Europa 11
AU - Australia 10
RU - Federazione Russa 10
AT - Austria 9
JP - Giappone 8
PK - Pakistan 8
RO - Romania 8
BR - Brasile 6
PE - Perù 5
IL - Israele 4
JO - Giordania 4
PH - Filippine 4
SG - Singapore 4
BD - Bangladesh 3
CL - Cile 3
RS - Serbia 3
CZ - Repubblica Ceca 2
EE - Estonia 2
EG - Egitto 2
GR - Grecia 2
KZ - Kazakistan 2
MX - Messico 2
NZ - Nuova Zelanda 2
AM - Armenia 1
AZ - Azerbaigian 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CH - Svizzera 1
EC - Ecuador 1
GE - Georgia 1
HU - Ungheria 1
KE - Kenya 1
KR - Corea 1
LA - Repubblica Popolare Democratica del Laos 1
LT - Lituania 1
MT - Malta 1
MY - Malesia 1
SA - Arabia Saudita 1
SI - Slovenia 1
TH - Thailandia 1
UZ - Uzbekistan 1
Totale 12.688
Città #
Southend 1.771
Dublin 975
Fairfield 783
Chandler 554
Ashburn 467
Siena 455
Jacksonville 430
Woodbridge 403
Ann Arbor 351
Wilmington 325
Seattle 324
Houston 299
Menlo Park 261
Cambridge 247
Princeton 173
Beijing 172
Nanjing 134
Dong Ket 91
New York 80
San Mateo 68
Málaga 61
Boardman 59
Nanchang 55
Shanghai 52
San Diego 51
Florence 48
Helsinki 47
Dearborn 42
Fremont 42
Shenyang 40
Rome 37
Hebei 35
Brussels 32
Redwood City 29
Kunming 23
Tianjin 22
Washington 22
Bagno a Ripoli 21
Changsha 19
Jiaxing 17
Ningbo 16
Izmir 15
Milan 15
Gdansk 14
London 14
Düsseldorf 13
Kansas City 12
Phoenix 12
Zhengzhou 12
Jinan 11
Toronto 11
Arezzo 10
Hangzhou 10
Lancaster 10
San Francisco 10
Chicago 9
Norwalk 9
University Park 9
Venezia 9
Vienna 9
Zanjan 9
Guangzhou 8
Tappahannock 8
Auburn Hills 7
Colle Di Val D'elsa 7
Atlanta 6
Hong Kong 6
Lanzhou 6
Nürnberg 6
Taizhou 6
Fuzhou 5
Kilburn 5
Leawood 5
Lima 5
Radomsko 5
Waukegan 5
Amman 4
Amsterdam 4
Catania 4
Changchun 4
Como 4
Cosenza 4
Grosseto 4
Hefei 4
Lappeenranta 4
Los Angeles 4
Melbourne 4
Napoli 4
Pontedera 4
Redmond 4
Sesto Fiorentino 4
Timisoara 4
Bangalore 3
Canberra 3
Capalbio 3
Castellina In Chianti 3
Costa Mesa 3
Council Bluffs 3
Dallas 3
Fucecchio 3
Totale 9.534
Nome #
Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging 259
Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumoniae and P. aeruginosa 244
The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells 244
Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe 240
The proteome speciation of an immortalized cystic fibrosis cell line: New perspectives on the pathophysiology of the disease 223
Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions. 211
Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug 205
In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate 203
Isomerization of an Antimicrobial Peptide Broadens Antimicrobial Spectrum to Gram-Positive Bacterial Pathogens 199
Tumor imaging with tetrabranched neurotensin 196
Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer 195
Supramolecular aggregates as drug carriers on cell expressing receptors for branched Neurotensin 186
Cancer selectivity of tetrabranched neurotensin peptides is generated by simultaneous binding to sulfated glycosaminoglycans and protein receptors. 186
Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity 184
Heparan Sulfate Proteoglycans Can Promote Opposite Effects on Adhesion and Directional Migration of Different Cancer Cells 176
Branched peptides for tumor diagnosis and therapy 165
Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate 164
Synergistic activity profile of an antimicrobial peptide against multidrug-resistant and extensively drug-resistant strains of Gram-negative bacterial pathogens 164
A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo. 159
Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase 158
Branched Neurotensin For Tumor Targeting 158
A new NT4 peptide-based drug delivery system for cancer treatment 158
D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions 156
Antimicrobial activity of levofloxacin - M33 peptide conjugation or combination 155
Branched peptides as bioactive molecules for drug design 153
An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue 152
Synthetic peptides in the form of dendrimers become resistant to protease activity 151
A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo. 150
A novel phage-library-selected peptide inhibits human TNF-α binding to its receptors 149
Modular Branched Neurotensin Peptides for Tumor Target Tracing and Receptor-Mediated Therapy: A Proof-of-Concept 148
Antimicrobial peptide-loaded nanoparticles as inhalation therapy for Pseudomonas aeruginosa infections 146
Esculentin-1a-derived peptides promote clearance of pseudomonas aeruginosa internalized in bronchial cells of cystic fibrosis patients and lung cell migration: Biochemical properties and a plausible mode of action 141
Large-scale screening of organ specific autoantibodies in patients with autoimmune thyroid diseases 141
Antimicrobial activity of novel dendrimeric peptides obtained by phage display selection and rational modification. 140
Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting 139
Antibacterial and anti-inflammatory activity of an antimicrobial peptide synthesized with D amino acids 138
Branched multimeric peptides for tumor diagnosis and therapy 136
Branched peptides as targeting agents for tumor imaging and therapy 136
Bioactive peptides from libraries 135
Antimicrobial peptide, branched forms thereof, and their use in the treatment of bacterial infections 135
Mimicking the nicotinic receptor binding site by a single chain Fv selected by competitive panning from a synthetic phage library 133
Targeting different LRP receptors and sulfated proteoglycan by branched neurotensin provide high cancer selectivity 133
Antibacterial peptides and analogues thereof 128
Branched neurotensin for tumor targeting 128
Design and in vitro evaluation of branched peptide conjugates:turning nonspecific cytotoxic drugs into tumor-selective agents. 127
Immunomodulatory and anti-inflammatory activity in vitro and in vivo of a novel antimicrobial candidate. 127
Branched neurotensin specifically binds a highly selective tumor cell marker, which is not neurotensin receptor 1 123
Molecular basis of branched peptides resistance to enzyme proteolysis 123
Neurotensin-derived branched peptides and uses thereof 121
COMPOSTI ANTI TNF-ALPHA E LORO USI 121
Biochemical filtering of a protein-protein docking simulation identifies the structure of a complex between a recombinant antibody fragment and alpha-bungarotoxin 119
Tumor imaging with tetrabranched neurotensin 119
Branched neurotensin specifically binds a highly selective tumor cell marker, which is not neurotensin receptor 1 118
BRANCHED PEPTIDES AS THERAPEUTICS 117
A branched peptide mimotope of the nicotinic receptor binding site is a potent synthetic antidote against the snake neurotoxin alpha-bungarotoxin 117
The development of antimicrobial peptides as new antibacterial drugs. 117
ANTICORPI E PEPTIDI -I farmaci del XXI secolo- 116
Mimotopes of the nicotinic receptor binding site selected by a combinatorial peptide library 116
Synthetic antidotes against snake neurotoxins 116
The antimicrobial peptide M33. An example of drug development 113
Dendrimeric peptide inhibitors of anthrax lethal and edema factor 112
Phage display and colony filter screening for high-throughput selection of antibody libraries 110
The antimicrobial peptide M33. An example of drug development 110
Antimicrobial activity of two novel antimicrobial peptides AA139 and SET-M33 against clinically and genotypically diverse Klebsiella pneumoniae isolates with differing antibiotic resistance profiles 110
Dendrimeric peptide inhibitors of anthrax lethal and edema factors 108
Branched Neurotensin peptides for tumor personalized therapy 107
Tumor selective targeting by branched peptides 107
TARGETING BY AFFINITY MATURED RECOMBINANT ANTIBODY FRAGMENTS OF AN ANGIOGENESIS ASSOCIATED FIBRONECTIN ISOFORM 106
Strategies for the construction and use of peptide and antibody libraries displayed on phages. 106
Endocytosis and trafficking of heparan sulfate proteoglycans in triple-negative breast cancer cells unraveled with a polycationic peptide 106
null 105
Solubility improvement of an anthrax toxin peptide inhibitor by rational aminoacid randomization 103
Biochemical characterization and strong in vivo activity of a novel antimicrobial peptide specific for gram-negative bacteria 103
Multiple Antigen Peptides (MAP) as antidotes against snake neurotoxin intoxication 102
Turning nonspecific cytotoxic drugs into tumor-selective agents via conjugation to branched peptides. 102
Target Selective Drug Delivery through Liposome Labeled with Oligobranched Neurotensin Peptides 101
Esculentin(1-21), an amphibian skin membrane-active peptide with potent activity on both planktonic and biofilm cells of the bacterial pathogen Pseudomonas aeruginosa. 100
Peptide sequences, their branched form and use thereof for antimicrobial applications 99
Rational design and molecular diversity for the construction of anti-alpha-bungarotoxin antidotes with high affinity and in vivo efficiency 97
Phage display of antibody fragments 96
Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo 94
Branched neurotensin peptides for tumor targeting 91
Synthetic peptides in the form of dendrimers can become resistant to protease activity 90
NMR study of the secondary structure and biopharmaceutical formulation of an active branched antimicrobial peptide 90
OLIGO-BRANCHED PEPTIDES FOR TUMOR TARGETING: FROM MAGIC BULLETS TO MAGIC FORKS. 87
Characterization of the branched antimicrobial peptide M6 by analyzing its mechanism of action and in vivo toxicity. 85
In vitro inhalation cytotoxicity testing of therapeutic nanosystems for pulmonary infection 84
Synthetic inhibitors of anthrax lethal toxin 82
null 78
Antimicrobial peptides active in in vitro models of endodontic bacterial infections modulate inflammation in human cardiac fibroblasts 75
null 75
Dendrimeric peptides for tumor targeting 70
STRONG SYNTHETIC INHIBITORS OF ANTHRAX LETHAL TOXIN 64
Peptide Drugs 63
Peptides mimotopes of the nicotinic receptor binding site 61
Rationally designed affinity maturation of a synthetic antidote against alpha-bungarotoxin 50
Turning Traditional Cytotoxic Drugs Into Tumour-selective Agents 40
Safety evaluations of a synthetic antimicrobial peptide administered intravenously in rats and dogs 38
In Vivo Efficacy and Toxicity of an Antimicrobial Peptide in a Model of Endotoxin-Induced Pulmonary Inflammation 32
Diagnostics of myasthenic syndromes: detection of anti-AChR and anti-MuSK antibodies 30
Totale 12.779
Categoria #
all - tutte 36.959
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.959


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019592 0 0 0 0 0 0 0 0 0 0 287 305
2019/20202.492 302 88 178 359 182 193 208 283 212 240 91 156
2020/20212.378 108 185 48 191 77 333 227 310 206 328 153 212
2021/20221.498 87 157 97 157 95 63 60 81 58 177 171 295
2022/20232.067 115 209 254 280 221 386 53 162 171 88 89 39
2023/20241.477 54 52 132 78 69 449 561 34 8 36 4 0
Totale 12.909