IRIS
PINI, ALESSANDRO
 Distribuzione geografica
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Continente #
NA - Nord America 9.187
EU - Europa 8.566
AS - Asia 4.178
SA - Sud America 677
AF - Africa 220
OC - Oceania 19
Continente sconosciuto - Info sul continente non disponibili 11
Totale 22.858
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Nazione #
US - Stati Uniti d'America 9.068
GB - Regno Unito 1.960
RU - Federazione Russa 1.623
CN - Cina 1.502
IT - Italia 1.376
SG - Singapore 1.209
IE - Irlanda 977
SE - Svezia 614
BR - Brasile 534
UA - Ucraina 527
DE - Germania 489
VN - Vietnam 426
FR - Francia 398
HK - Hong Kong 320
KR - Corea 237
FI - Finlandia 220
IN - India 133
ZA - Sudafrica 126
ES - Italia 82
BD - Bangladesh 64
CA - Canada 64
PL - Polonia 63
BE - Belgio 59
AR - Argentina 50
NL - Olanda 47
PK - Pakistan 38
JP - Giappone 36
TR - Turchia 36
MX - Messico 31
AT - Austria 26
IR - Iran 24
CZ - Repubblica Ceca 23
VE - Venezuela 20
NG - Nigeria 19
CL - Cile 18
IQ - Iraq 18
EC - Ecuador 17
AU - Australia 16
CH - Svizzera 16
KE - Kenya 16
CO - Colombia 14
PH - Filippine 13
AZ - Azerbaigian 12
CI - Costa d'Avorio 12
UZ - Uzbekistan 12
EU - Europa 11
LT - Lituania 11
RO - Romania 11
DZ - Algeria 10
IL - Israele 10
JO - Giordania 10
KZ - Kazakistan 10
AE - Emirati Arabi Uniti 9
EG - Egitto 9
ID - Indonesia 9
PE - Perù 9
TN - Tunisia 9
MA - Marocco 8
SA - Arabia Saudita 8
TW - Taiwan 7
DK - Danimarca 6
PY - Paraguay 6
BO - Bolivia 5
BY - Bielorussia 5
EE - Estonia 5
ET - Etiopia 5
MY - Malesia 5
BG - Bulgaria 4
CR - Costa Rica 4
DO - Repubblica Dominicana 4
JM - Giamaica 4
LA - Repubblica Popolare Democratica del Laos 4
NP - Nepal 4
OM - Oman 4
RS - Serbia 4
AL - Albania 3
AM - Armenia 3
BB - Barbados 3
GR - Grecia 3
GY - Guiana 3
LV - Lettonia 3
NZ - Nuova Zelanda 3
PA - Panama 3
BA - Bosnia-Erzegovina 2
KG - Kirghizistan 2
LB - Libano 2
PT - Portogallo 2
SI - Slovenia 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
AO - Angola 1
BN - Brunei Darussalam 1
CM - Camerun 1
CY - Cipro 1
GD - Grenada 1
GE - Georgia 1
HN - Honduras 1
HU - Ungheria 1
LK - Sri Lanka 1
MD - Moldavia 1
Totale 22.843
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Città #
Southend 1.750
Dallas 1.045
Dublin 965
Fairfield 778
Ashburn 670
Singapore 669
Chandler 554
Siena 483
Moscow 461
Jacksonville 426
Santa Clara 402
Woodbridge 400
Beijing 380
Ann Arbor 349
San Jose 326
Seattle 326
Wilmington 321
Houston 304
Hong Kong 298
Hefei 287
Menlo Park 260
Cambridge 246
Seoul 234
Princeton 171
Los Angeles 162
The Dalles 145
New York 139
Nanjing 133
Council Bluffs 130
Johannesburg 120
Milan 108
Ho Chi Minh City 104
Helsinki 96
Munich 94
Lauterbourg 93
Dong Ket 87
Boardman 84
Hanoi 78
Florence 77
San Mateo 67
Rome 66
Málaga 60
Shanghai 60
Buffalo 58
Nanchang 56
São Paulo 52
San Diego 51
Dearborn 42
Fremont 42
Shenyang 41
Orem 40
London 39
Bengaluru 37
Brussels 37
Hebei 34
Turku 34
Warsaw 34
Chicago 31
Redwood City 29
Frankfurt am Main 26
Toronto 26
Brooklyn 25
Tianjin 25
Tokyo 25
Chennai 24
Kunming 24
Redondo Beach 24
Washington 24
Columbus 23
Stockholm 22
Bagno a Ripoli 21
Da Nang 21
Porto Alegre 21
Changsha 20
Montreal 20
Phoenix 20
Abuja 19
Brno 19
Dhaka 19
Nuremberg 19
Amsterdam 18
Denver 18
Düsseldorf 18
San Francisco 18
Atlanta 17
Guangzhou 17
Jiaxing 17
Vienna 17
Belo Horizonte 16
Lappeenranta 16
Manchester 16
Ningbo 16
Hangzhou 15
Izmir 15
Paris 15
Rio de Janeiro 15
Zhengzhou 15
Brasília 14
Gdansk 14
Haiphong 14
Totale 15.453
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Nome #
Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging 372
Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe 362
The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells 357
Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumoniae and P. aeruginosa 353
Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug 335
A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo. 323
Heparan sulfate proteoglycans can promote opposite effects on adhesion and directional migration of different cancer cells 318
Cancer selectivity of tetrabranched neurotensin peptides is generated by simultaneous binding to sulfated glycosaminoglycans and protein receptors. 309
An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue 306
A new NT4 peptide-based drug delivery system for cancer treatment 301
A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo 300
Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions 300
Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer 298
Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity 297
The proteome speciation of an immortalized cystic fibrosis cell line: New perspectives on the pathophysiology of the disease 295
A novel phage-library-selected peptide inhibits human TNF-α binding to its receptors 291
Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate 283
Isomerization of an Antimicrobial Peptide Broadens Antimicrobial Spectrum to Gram-Positive Bacterial Pathogens 283
Analysis of the utility of a rapid vesicle isolation method for clinical strains of Pseudomonas aeruginosa 282
Antimicrobial peptide-loaded nanoparticles as inhalation therapy for Pseudomonas aeruginosa infections 276
Antimicrobial activity of novel dendrimeric peptides obtained by phage display selection and rational modification. 274
In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate 272
Antibacterial and anti-inflammatory activity of an antimicrobial peptide synthesized with D amino acids 272
Tumor imaging with tetrabranched neurotensin 267
A branched peptide mimotope of the nicotinic receptor binding site is a potent synthetic antidote against the snake neurotoxin alpha-bungarotoxin 264
Antibacterial and Anti-Inflammatory Activity of Branched Peptides Derived from Natural Host Defense Sequences 262
Antimicrobial activity of levofloxacin - M33 peptide conjugation or combination 262
Large-scale screening of organ specific autoantibodies in patients with autoimmune thyroid diseases 261
Branched peptides as bioactive molecules for drug design 259
Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase 257
Supramolecular aggregates as drug carriers on cell expressing receptors for branched Neurotensin 256
Branched peptides for tumor diagnosis and therapy 248
Branched Neurotensin For Tumor Targeting 247
Antimicrobial peptides active in in vitro models of endodontic bacterial infections modulate inflammation in human cardiac fibroblasts 246
Antibacterial peptides and analogues thereof 245
Bioactive peptides from libraries 241
Modular Branched Neurotensin Peptides for Tumor Target Tracing and Receptor-Mediated Therapy: A Proof-of-Concept 241
Branched peptides as targeting agents for tumor imaging and therapy 237
Esculentin-1a-derived peptides promote clearance of pseudomonas aeruginosa internalized in bronchial cells of cystic fibrosis patients and lung cell migration: Biochemical properties and a plausible mode of action 237
Branched neurotensin specifically binds a highly selective tumor cell marker, which is not neurotensin receptor 1 232
D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions 231
Dendrimeric peptide inhibitors of anthrax lethal and edema factors 230
Antimicrobial peptide, branched forms thereof, and their use in the treatment of bacterial infections 228
Biochemical filtering of a protein-protein docking simulation identifies the structure of a complex between a recombinant antibody fragment and alpha-bungarotoxin 227
Branched Neurotensin peptides for tumor personalized therapy 225
Branched multimeric peptides for tumor diagnosis and therapy 221
Endocytosis and trafficking of heparan sulfate proteoglycans in triple-negative breast cancer cells unraveled with a polycationic peptide 221
Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting 221
Synthetic peptides in the form of dendrimers become resistant to protease activity 220
Targeting different LRP receptors and sulfated proteoglycan by branched neurotensin provide high cancer selectivity 217
Mimicking the nicotinic receptor binding site by a single chain Fv selected by competitive panning from a synthetic phage library 215
Synergistic activity profile of an antimicrobial peptide against multidrug-resistant and extensively drug-resistant strains of Gram-negative bacterial pathogens 212
Antimicrobial activity of two novel antimicrobial peptides AA139 and SET-M33 against clinically and genotypically diverse Klebsiella pneumoniae isolates with differing antibiotic resistance profiles 211
Turning nonspecific cytotoxic drugs into tumor-selective agents via conjugation to branched peptides. 209
ANTICORPI E PEPTIDI -I farmaci del XXI secolo- 208
Branched neurotensin specifically binds a highly selective tumor cell marker, which is not neurotensin receptor 1 207
Design and in vitro evaluation of branched peptide conjugates:turning nonspecific cytotoxic drugs into tumor-selective agents 206
The antimicrobial peptide M33. An example of drug development 206
Branched neurotensin for tumor targeting 205
The development of antimicrobial peptides as new antibacterial drugs 204
Tumor selective targeting by branched peptides 200
Branched oncolytic peptides target HSPGs, inhibit metastasis, and trigger the release of molecular determinants of immunogenic cell death in pancreatic cancer 198
Biochemical characterization and strong in vivo activity of a novel antimicrobial peptide specific for gram-negative bacteria 197
Molecular basis of branched peptides resistance to enzyme proteolysis 197
Mimotopes of the nicotinic receptor binding site selected by a combinatorial peptide library 194
Neurotensin-derived branched peptides and uses thereof 192
Branched peptides as therapeutics 186
NMR study of the secondary structure and biopharmaceutical formulation of an active branched antimicrobial peptide 186
Phage display and colony filter screening for high-throughput selection of antibody libraries 185
Characterization of the branched antimicrobial peptide M6 by analyzing its mechanism of action and in vivo toxicity. 183
Dendrimeric peptide inhibitors of anthrax lethal and edema factor 179
COMPOSTI ANTI TNF-ALPHA E LORO USI 177
Antimicrobial Peptides towards Clinical Application-A Long History to Be Concluded 173
Synthetic antidotes against snake neurotoxins 173
Target Selective Drug Delivery through Liposome Labeled with Oligobranched Neurotensin Peptides 173
In Vivo Efficacy and Toxicity of an Antimicrobial Peptide in a Model of Endotoxin-Induced Pulmonary Inflammation 171
Esculentin(1-21), an amphibian skin membrane-active peptide with potent activity on both planktonic and biofilm cells of the bacterial pathogen Pseudomonas aeruginosa 168
The antimicrobial peptide M33. An example of drug development 167
Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform 165
The tardigrade damage suppressor protein modulates transcription factor and DNA repair genes in human cells treated with hydroxyl radicals and UV-C 164
Multiple Antigen Peptides (MAP) as antidotes against snake neurotoxin intoxication 164
Branched neurotensin peptides for tumor targeting 162
Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo 161
Tumor imaging with tetrabranched neurotensin 161
Targeting heparan sulfate proteoglycans as an effective strategy for inhibiting cancer cell migration and invasiveness compared to heparin 159
Solubility improvement of an anthrax toxin peptide inhibitor by rational aminoacid randomization 157
Safety evaluations of a synthetic antimicrobial peptide administered intravenously in rats and dogs 155
Dendrimeric peptides for tumor targeting 155
Oligo-branched peptides for tumor targeting: From magic bullets to magic forks 155
Strategies for the construction and use of peptide and antibody libraries displayed on phages. 153
Peptide sequences, their branched form and use thereof for antimicrobial applications 152
Screening of organ-specific autoantibodies in a large cohort of patients with autoimmune thyroid diseases. 152
In vitro inhalation cytotoxicity testing of therapeutic nanosystems for pulmonary infection 150
Inhalable Polymeric Nanoparticles for Pulmonary Delivery of Antimicrobial Peptide SET-M33: antibacterial activity and toxicity in vitro and in vivo 143
Phage display of antibody fragments 143
Synthetic inhibitors of anthrax lethal toxin 139
Synthetic peptides in the form of dendrimers can become resistant to protease activity 139
Pulmonary Safety Profile of Esc Peptides and Esc-Peptide-Loaded Poly(lactide-co-glycolide) Nanoparticles: A Promising Therapeutic Approach for Local Treatment of Lung Infectious Diseases 137
Rational design and molecular diversity for the construction of anti-alpha-bungarotoxin antidotes with high affinity and in vivo efficiency 137
Turning Traditional Cytotoxic Drugs Into Tumour-selective Agents 134
Totale 22.281
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Categoria #
all - tutte 67.443
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.443
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021668 0 0 0 0 0 0 0 0 0 310 152 206
2021/20221.476 87 157 96 157 93 62 60 78 58 165 171 292
2022/20232.050 114 207 253 279 221 384 50 161 170 85 87 39
2023/20241.572 51 49 130 77 69 440 550 34 8 35 20 109
2024/20253.193 72 140 358 185 390 181 126 200 241 119 331 850
2025/20267.054 565 1.040 846 930 1.470 312 846 261 331 453 0 0
Totale 23.130