IRIS
BRIZZI, ANTONELLA
 Distribuzione geografica
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Continente #
EU - Europa 5.387
NA - Nord America 5.341
AS - Asia 2.587
SA - Sud America 448
AF - Africa 125
OC - Oceania 14
Continente sconosciuto - Info sul continente non disponibili 1
Totale 13.903
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Nazione #
US - Stati Uniti d'America 5.248
GB - Regno Unito 1.210
IT - Italia 1.145
RU - Federazione Russa 958
CN - Cina 842
SG - Singapore 775
IE - Irlanda 620
BR - Brasile 367
SE - Svezia 301
FR - Francia 288
DE - Germania 276
VN - Vietnam 251
UA - Ucraina 238
HK - Hong Kong 217
FI - Finlandia 147
KR - Corea 147
IN - India 99
ZA - Sudafrica 61
TR - Turchia 49
CA - Canada 41
MX - Messico 36
BD - Bangladesh 35
JP - Giappone 34
NL - Olanda 34
PL - Polonia 33
ES - Italia 29
AR - Argentina 28
NG - Nigeria 18
PK - Pakistan 17
AT - Austria 16
BE - Belgio 16
IQ - Iraq 16
EC - Ecuador 14
ID - Indonesia 14
AU - Australia 13
TW - Taiwan 12
CI - Costa d'Avorio 10
AE - Emirati Arabi Uniti 8
CL - Cile 8
CZ - Repubblica Ceca 8
PT - Portogallo 8
VE - Venezuela 8
GR - Grecia 7
KE - Kenya 7
SA - Arabia Saudita 7
UZ - Uzbekistan 7
CH - Svizzera 6
CO - Colombia 6
EE - Estonia 6
IL - Israele 6
JO - Giordania 6
LT - Lituania 6
MY - Malesia 6
SN - Senegal 6
AM - Armenia 5
AZ - Azerbaigian 5
DZ - Algeria 5
EG - Egitto 5
IR - Iran 5
PY - Paraguay 5
SI - Slovenia 5
SK - Slovacchia (Repubblica Slovacca) 5
LV - Lettonia 4
MA - Marocco 4
PE - Perù 4
TN - Tunisia 4
AL - Albania 3
CM - Camerun 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
GE - Georgia 3
LK - Sri Lanka 3
NP - Nepal 3
RS - Serbia 3
SR - Suriname 3
SY - Repubblica araba siriana 3
UY - Uruguay 3
ET - Etiopia 2
HR - Croazia 2
HU - Ungheria 2
JM - Giamaica 2
KG - Kirghizistan 2
KZ - Kazakistan 2
MK - Macedonia 2
NO - Norvegia 2
PA - Panama 2
PH - Filippine 2
RO - Romania 2
SV - El Salvador 2
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
BO - Bolivia 1
BY - Bielorussia 1
DK - Danimarca 1
DM - Dominica 1
EU - Europa 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
Totale 13.895
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Città #
Southend 1.081
Dallas 724
Dublin 618
Fairfield 498
Singapore 448
Ashburn 355
Siena 309
Santa Clara 268
Moscow 266
Menlo Park 252
Beijing 251
Chandler 251
Woodbridge 231
Hong Kong 202
Wilmington 196
San Jose 190
Jacksonville 185
Hefei 169
Seattle 165
Houston 160
Cambridge 143
Seoul 141
Ann Arbor 138
Milan 114
Princeton 108
Los Angeles 101
Florence 91
Helsinki 86
The Dalles 79
Nanjing 77
Ho Chi Minh City 76
Lauterbourg 69
Hanoi 65
Council Bluffs 64
Johannesburg 58
New York 57
Fremont 53
Rome 46
Boardman 42
Munich 42
San Mateo 38
São Paulo 34
Bengaluru 30
Dearborn 30
Frankfurt am Main 27
London 27
San Diego 27
Tokyo 27
Izmir 25
Shanghai 24
Buffalo 22
Nanchang 21
Orem 21
Naples 20
Redondo Beach 20
Düsseldorf 19
Shenyang 19
Abuja 18
Columbus 18
Chicago 17
Turku 17
Chennai 16
Brooklyn 15
Tianjin 15
Warsaw 15
Brussels 14
Guangzhou 13
Haiphong 13
Paris 13
Manchester 12
Nuremberg 12
San Francisco 12
Vienna 12
Amsterdam 11
Bari 11
Hebei 11
Montreal 11
Piscataway 11
Abidjan 10
Cardiff 10
Dong Ket 10
Kunming 10
L’Aquila 10
Norwalk 10
Redwood City 10
Rio de Janeiro 10
Bologna 9
Brescia 9
Lappeenranta 9
Mexico City 9
Mogliano 9
Mumbai 9
Palermo 9
Toronto 9
Washington 9
Zhengzhou 9
Candiolo 8
Denver 8
Falkenstein 8
Jakarta 8
Totale 9.389
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Nome #
Ligandi TRPV1 480
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 397
Cytotoxic effects of cannabinoids on human HT-29 colorectal adenocarcinoma cells: different mechanisms of THC, CBD, and CB83 355
1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 and CB2 receptor ligands 354
Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease 300
Nuclear magnetic resonance for studying recognition processes between anandamide and cannabinoid receptors 296
Quercetin/oleic acid-based G-protein-coupled receptor 40 ligands as new insulin secretion modulators 293
Synthesis of pyrazolo[1,5-a]pyrimidine ring as a possible bioisosteric replacement of the 5-(1H-pyrrol-1-yl)pyrazole scaffold 285
New fluoroquinolones active against fluoroquinolones-resistant Mycobacterium tuberculosis strains 272
Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors 269
Development and characterization of immobilized cannabinoid receptor (CB1/CB2) open tubular column for on-line screening 261
Suppressing effect of COR659 on alcohol, sucrose, and chocolate self-administration in rats: Involvement of the GABAB and cannabinoid CB1 receptors 252
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility 250
Screen of unfocused libraries identified compounds with direct or synergistic antibacterial activity 242
Synthesis and biological evaluation of New N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands 241
Anti-Inflammatory and Antinociceptive Properties of the Quercetin-3-Oleate AV2, a Novel FFAR1 Partial Agonist 240
Synthesis and in vitro pharmacological activity of oxypropanol analogs of labetalol 237
Regioselective functionalization of quinolin-4(1H)-ones via sequential palladium-catalyzed reactions 237
Dihydro-alkylthio-benzyl-oxopyrimidines as Inhibitors of Reverse Transcriptase: Synthesis and Rationalization of the Biological Data on Both Wild-Type Enzyme and Relevant Clinical Mutants 237
Design, Synthesis, and Binding Studies of New Potent Ligands of Cannabinoids Receptors 231
Design, synthesis, and physicochemical and pharmacological profiling of 7‐Hydroxy-5-oxopyrazolo[4,3‐b]pyridine-6-carboxamide derivatives with antiosteoarthritic activity in vivo 228
A multitarget semi-synthetic derivative of the flavonoid morin with improved in vitro vasorelaxant activity: Role of CaV1.2 and KCa1.1 channels 227
New Resorcinol-Anandamide "Hybrids" as Potent Cannabinoid Receptor Ligands Endowed with antinociceptive activity in vivo 225
The Interactions of the 5-HT3 Receptor with Quipazine-Like Arylpiperazine Ligands. The Journey Track at the End of the First Decade of the Third Millennium 224
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 6. Synthesis and Pharmacological Evaluation of 7-Substituted 4-Quinolone-3-carboxamide Derivatives as High Affinity Ligands for Cannabinoid Receptors 224
Nuovi Potenti e Selettivi ligandi dei recettori dei cannabinoidi 220
Synthesis and antitumor activities of a series of novel quinoxalinhydrazides 219
3-Amino-alkylated indoles: Unexplored green products acting as anti-inflammatory agents 219
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one derivatives 215
Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors 213
Synthesis, Cannabinoid Receptor Affinity, and Molecular Modeling Studies of Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides 212
Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular KCa1.1 channel stimulators 212
2-Hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl(E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: synthesis, in silico analysis and in vitro pharmacological evaluation 212
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists 210
Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands 206
Conformational Analysis of the N-Arachinylethanolamide (Anandamide) using Nuclear Magnetic Resonance and Theoretical Calculations 205
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol (2-AG) Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 (CB1) Receptor 204
TRPV1-FAAH-COX: The Couples Game in Pain Treatment 199
Synthetic bioactive olivetol-related amides: the influence of the phenolic group in cannabinoid receptor activity 198
Anti-addictive properties of COR659 – Additional pharmacological evidence and comparison with a series of novel analogues 196
Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors 194
HIV-Reverse Transcriptase Inhibition: Inclusion of Ligand-Induced Fit by Cross-Docking Studies 190
Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist 187
Thiazolothiazepine Inhibitors of HIV-1 Integrase 177
Light-mediated activation/deactivation control and in vitro ADME-Tox profiling of a donepezil-like Dual AChE/MAO-B Inhibitor 175
Identification and Quantification of Trans-Resveratrol in Dietary Supplements by a Rapid and Straightforward RP-HPLC Method 174
Pinocembrin and its linolenoyl ester derivative induce wound healing activity in HaCaT cell line potentially involving a GPR120/FFA4 mediated pathway 174
Design, synthesis and in vitro experimental validation of novel TRPV4 antagonists inspired by labdane diterpenes 167
Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile 164
Optimization of Pyrazole Compounds as Antibiotic Adjuvants Active against Colistin- and Carbapenem-Resistant Acinetobacter baumannii 163
Polycondensed Heterocycles. Part 11: Preparation and Regioselective Reductions of 5-Phenyl-4H-pyrrolo[1,2-a][1]benzazepin-4-one 162
An approach to the stereo-controlled synthesis of polycyclic derivatives of L-4-thiazolidinecarboxilic acid active against HIV-1 integrase 156
Lipoic/Capsaicin-Related Amides: Synthesis and Biological Characterization of New TRPV1 Agonists Endowed with Protective Properties against Oxidative Stress 155
Suppressing effect of the novel positive allosteric modulator of the GABAB receptor, COR659, on locomotor hyperactivity induced by different drugs of abuse 154
Napthoxazepine Inhibitors of HIV-1 Integrase: Synthesis and Biological Evaluation 142
Synthesis of some novel 1-aryl-1H-1,2,3-triazole-4-carboxamides and ethyl 1-aryl-5-(1,2,3-triazol-1-yl)-1H-pyrazole-4-carboxylates 141
New synthesis of N1- and N2-substituted pyrazolo[4,3-b]pyridine-5-one derivatives as CB2 receptor ligands 137
Indole-2-Carboxamide as an Effective Scaffold for the Design of New TRPV1 Agonists 134
In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands 127
Targeting neuropathic pain: pathobiology, current treatment and peptidomimetics as a new therapeutic opportunity 127
GPR120/FFAR4 pharmacology: focus on agonists in Type 2 diabetes mellitus drug discovery 122
Development of 1-(2-aminophenyl)pyrrole-based amides acting as human topoisomerase I inhibitors 121
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor 118
Old strategies and new perspectives in modulating the endocannabinoid system 116
Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo 115
Investigation on Novel E/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity 112
The GABAB receptor positive allosteric modulator COR659: in vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives 101
Structure optimization of positive allosteric modulators of GABAB receptors led to the unexpected discovery of antagonists/potential negative allosteric modulators 99
Totale 14.101
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Categoria #
all - tutte 42.161
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.161
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021434 0 0 0 0 0 0 0 0 0 245 116 73
2021/20221.054 84 121 97 102 64 41 50 55 45 113 96 186
2022/20231.150 81 88 177 136 100 225 45 92 91 29 60 26
2023/20241.133 58 24 92 63 63 236 363 36 17 40 28 113
2024/20252.156 59 98 230 127 247 145 98 134 178 114 207 519
2025/20264.524 390 779 575 586 876 192 581 165 169 211 0 0
Totale 14.101