BRIZZI, ANTONELLA
BRIZZI, ANTONELLA
Dipartimento di Biotecnologie, Chimica e Farmacia
1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 and CB2 receptor ligands
2011-01-01 Piscitelli, F; Ligresti, A; LA REGINA, G; Gatti, V; Brizzi, Antonella; Pasquini, Serena; Allarà, M; CARAI M. A., M; Novellino, E; Colombo, G; DI MARZO, V; Corelli, Federico; Silvestri, R.
2-Hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl(E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: synthesis, in silico analysis and in vitro pharmacological evaluation
2021-01-01 Brizzi, A.; Trezza, A.; Spiga, O.; Maramai, S.; Scorzelli, F.; Saponara, S.; Fusi, F.
3-Amino-alkylated indoles: Unexplored green products acting as anti-inflammatory agents
2020-01-01 Mazzotta, S.; Frattaruolo, L.; Brindisi, M.; Ulivieri, C.; Vanni, F.; Brizzi, A.; Carullo, G.; Cappello, A. R.; Aiello, F.
A multitarget semi-synthetic derivative of the flavonoid morin with improved in vitro vasorelaxant activity: Role of CaV1.2 and KCa1.1 channels
2021-01-01 Carullo, G.; Ahmed, A.; Trezza, A.; Spiga, O.; Brizzi, A.; Saponara, S.; Fusi, F.; Aiello, F.
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one derivatives
2013-01-01 Fedora, Grande; Brizzi, Antonella; Garofalo, Antonio; Francesca, Aiello
An approach to the stereo-controlled synthesis of polycyclic derivatives of L-4-thiazolidinecarboxilic acid active against HIV-1 integrase
2006-01-01 Aiello, F.; Brizzi, Antonella; De Grazia, O.; Garofalo, A.; Grande, F.; Sinicropi, M. S.; Dayam, R.; Neamati, N.
Anti-addictive properties of COR659 – Additional pharmacological evidence and comparison with a series of novel analogues
2019-01-01 Maccioni, Paola; Colombo, Giancarlo; Lorrai, Irene; Fara, Federica; Carai, Mauro A. M.; Gessa, Gian Luigi; Brizzi, Antonella; Mugnaini, Claudia; Corelli, Federico
Anti-Inflammatory and Antinociceptive Properties of the Quercetin-3-Oleate AV2, a Novel FFAR1 Partial Agonist
2024-01-01 Pessina, Federica; Casini, Ilenia; Gamberucci, Alessandra; Carullo, Gabriele; Signorini, Cinzia; Brizzi, Antonella; Aiello, Francesca; Aloisi, Anna Maria; Pieretti, Stefano
Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors
2021-01-01 Fiorucci, Diego; Milletti, Eva; Orofino, Francesco; Brizzi, Antonella; Mugnaini, Claudia; Corelli, Federico
Conformational Analysis of the N-Arachinylethanolamide (Anandamide) using Nuclear Magnetic Resonance and Theoretical Calculations
2001-01-01 Bonechi, Claudia; Brizzi, Antonella; Brizzi, Vittorio; M., Francioli; Donati, Alessandro; Rossi, Claudio
Cytotoxic effects of cannabinoids on human HT-29 colorectal adenocarcinoma cells: different mechanisms of THC, CBD, and CB83
2020-01-01 Cerretani, Daniela; Collodel, Giulia; Brizzi, Antonella; Fiaschi, ANNA IDA; Menchiari, Andrea; Moretti, Elena; Moltoni, Laura; Micheli, Lucia
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress
2016-01-01 Aiello, F.; Badolato, M.; Pessina, Federica; Sticozzi, C.; Maestrini, Vanessa; Aldinucci, C.; Luongo, L.; Guida, F.; Ligresti, A.; Artese, A.; Allarà, M.; Costa, G.; Frosini, Maria; Schiano Morello, A.; De Petrocellis, L.; Valacchi, G.; Alcaro, S.; Maione, S.; Di Marzo, V.; Corelli, Federico; Brizzi, Antonella
Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors
2022-01-01 Paolino, Marco; Rullo, Mariagrazia; Maramai, Samuele; de Candia, Modesto; Pisani, Leonardo; Catto, Marco; Mugnaini, Claudia; Brizzi, Antonella; Cappelli, Andrea; Olivucci, Massimo; Corelli, Federico; Altomare, Cosimo D
Design, synthesis and in vitro experimental validation of novel TRPV4 antagonists inspired by labdane diterpenes
2020-01-01 Mazzotta, S.; Carullo, G.; Schiano Moriello, A.; Amodeo, P.; Di Marzo, V.; Vega-Holm, M.; Vitale, R. M.; Aiello, F.; Brizzi, A.; De Petrocellis, L.
Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular KCa1.1 channel stimulators
2020-01-01 Carullo, G.; Ahmed, A.; Trezza, A.; Spiga, O.; Brizzi, A.; Saponara, S.; Fusi, F.; Aiello, F.
Design, Synthesis, and Binding Studies of New Potent Ligands of Cannabinoids Receptors
2005-01-01 Brizzi, Antonella; Brizzi, Vittorio; Cascio, M. G.; Bisogno, T.; Sirianni, Rossella; Dimarzo, V.
Design, synthesis, and physicochemical and pharmacological profiling of 7‐Hydroxy-5-oxopyrazolo[4,3‐b]pyridine-6-carboxamide derivatives with antiosteoarthritic activity in vivo
2020-01-01 Mugnaini, Claudia; Kostrzewa, Magdalena; Bryk, Marta; Mokhtar Mahmoud, Ali; Brizzi, Antonella; Lamponi, Stefania; Giorgi, Gianluca; Ferlenghi, Francesca; Vacondio, Federica; Maccioni, Paola; Colombo, Giancarlo; Mor, Marco; Starowicz, Katarzyna; Di Marzo, Vincenzo; Ligresti, Alessia; Corelli, Federico
Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors
2007-01-01 Brizzi, Antonella; Cascio, M. G.; Brizzi, Vittorio; Bisogno, T.; Dinatolo, Maria Teresa; Martinelli, A.; Tuccinardi, T.; Di Marzo, V.
Development and characterization of immobilized cannabinoid receptor (CB1/CB2) open tubular column for on-line screening
2011-01-01 Moaddel, R.; Rosenberg, A.; Spelman, K.; Frazier, J.; Frazier, C.; Nocerino, S.; Brizzi, Antonella; Mugnaini, Claudia; Wainer, I. W.
Development of 1-(2-aminophenyl)pyrrole-based amides acting as human topoisomerase I inhibitors
2023-01-01 Carullo, Gabriele; Mazzotta, Sarah; Ceramella, Jessica; Iacopetta, Domenico; Ramunno, Anna; Rosano, Camillo; Brizzi, Antonella; Campiani, Giuseppe; Aiello, Francesca; Sinicropi, Maria S
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 and CB2 receptor ligands | 1-gen-2011 | Piscitelli, F; Ligresti, A; LA REGINA, G; Gatti, V; Brizzi, Antonella; Pasquini, Serena; Allarà, M; CARAI M. A., M; Novellino, E; Colombo, G; DI MARZO, V; Corelli, Federico; Silvestri, R. | - | |
| 2-Hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl(E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: synthesis, in silico analysis and in vitro pharmacological evaluation | 1-gen-2021 | Brizzi, A.; Trezza, A.; Spiga, O.; Maramai, S.; Scorzelli, F.; Saponara, S.; Fusi, F. | - | |
| 3-Amino-alkylated indoles: Unexplored green products acting as anti-inflammatory agents | 1-gen-2020 | Mazzotta, S.; Frattaruolo, L.; Brindisi, M.; Ulivieri, C.; Vanni, F.; Brizzi, A.; Carullo, G.; Cappello, A. R.; Aiello, F. | - | |
| A multitarget semi-synthetic derivative of the flavonoid morin with improved in vitro vasorelaxant activity: Role of CaV1.2 and KCa1.1 channels | 1-gen-2021 | Carullo, G.; Ahmed, A.; Trezza, A.; Spiga, O.; Brizzi, A.; Saponara, S.; Fusi, F.; Aiello, F. | - | |
| Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one derivatives | 1-gen-2013 | Fedora, Grande; Brizzi, Antonella; Garofalo, Antonio; Francesca, Aiello | - | |
| An approach to the stereo-controlled synthesis of polycyclic derivatives of L-4-thiazolidinecarboxilic acid active against HIV-1 integrase | 1-gen-2006 | Aiello, F.; Brizzi, Antonella; De Grazia, O.; Garofalo, A.; Grande, F.; Sinicropi, M. S.; Dayam, R.; Neamati, N. | - | |
| Anti-addictive properties of COR659 – Additional pharmacological evidence and comparison with a series of novel analogues | 1-gen-2019 | Maccioni, Paola; Colombo, Giancarlo; Lorrai, Irene; Fara, Federica; Carai, Mauro A. M.; Gessa, Gian Luigi; Brizzi, Antonella; Mugnaini, Claudia; Corelli, Federico | - | |
| Anti-Inflammatory and Antinociceptive Properties of the Quercetin-3-Oleate AV2, a Novel FFAR1 Partial Agonist | 1-gen-2024 | Pessina, Federica; Casini, Ilenia; Gamberucci, Alessandra; Carullo, Gabriele; Signorini, Cinzia; Brizzi, Antonella; Aiello, Francesca; Aloisi, Anna Maria; Pieretti, Stefano | - | |
| Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors | 1-gen-2021 | Fiorucci, Diego; Milletti, Eva; Orofino, Francesco; Brizzi, Antonella; Mugnaini, Claudia; Corelli, Federico | - | |
| Conformational Analysis of the N-Arachinylethanolamide (Anandamide) using Nuclear Magnetic Resonance and Theoretical Calculations | 1-gen-2001 | Bonechi, Claudia; Brizzi, Antonella; Brizzi, Vittorio; M., Francioli; Donati, Alessandro; Rossi, Claudio | - | |
| Cytotoxic effects of cannabinoids on human HT-29 colorectal adenocarcinoma cells: different mechanisms of THC, CBD, and CB83 | 1-gen-2020 | Cerretani, Daniela; Collodel, Giulia; Brizzi, Antonella; Fiaschi, ANNA IDA; Menchiari, Andrea; Moretti, Elena; Moltoni, Laura; Micheli, Lucia | - | |
| Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress | 1-gen-2016 | Aiello, F.; Badolato, M.; Pessina, Federica; Sticozzi, C.; Maestrini, Vanessa; Aldinucci, C.; Luongo, L.; Guida, F.; Ligresti, A.; Artese, A.; Allarà, M.; Costa, G.; Frosini, Maria; Schiano Morello, A.; De Petrocellis, L.; Valacchi, G.; Alcaro, S.; Maione, S.; Di Marzo, V.; Corelli, Federico; Brizzi, Antonella | - | |
| Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors | 1-gen-2022 | Paolino, Marco; Rullo, Mariagrazia; Maramai, Samuele; de Candia, Modesto; Pisani, Leonardo; Catto, Marco; Mugnaini, Claudia; Brizzi, Antonella; Cappelli, Andrea; Olivucci, Massimo; Corelli, Federico; Altomare, Cosimo D | - | |
| Design, synthesis and in vitro experimental validation of novel TRPV4 antagonists inspired by labdane diterpenes | 1-gen-2020 | Mazzotta, S.; Carullo, G.; Schiano Moriello, A.; Amodeo, P.; Di Marzo, V.; Vega-Holm, M.; Vitale, R. M.; Aiello, F.; Brizzi, A.; De Petrocellis, L. | - | |
| Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular KCa1.1 channel stimulators | 1-gen-2020 | Carullo, G.; Ahmed, A.; Trezza, A.; Spiga, O.; Brizzi, A.; Saponara, S.; Fusi, F.; Aiello, F. | - | |
| Design, Synthesis, and Binding Studies of New Potent Ligands of Cannabinoids Receptors | 1-gen-2005 | Brizzi, Antonella; Brizzi, Vittorio; Cascio, M. G.; Bisogno, T.; Sirianni, Rossella; Dimarzo, V. | - | |
| Design, synthesis, and physicochemical and pharmacological profiling of 7‐Hydroxy-5-oxopyrazolo[4,3‐b]pyridine-6-carboxamide derivatives with antiosteoarthritic activity in vivo | 1-gen-2020 | Mugnaini, Claudia; Kostrzewa, Magdalena; Bryk, Marta; Mokhtar Mahmoud, Ali; Brizzi, Antonella; Lamponi, Stefania; Giorgi, Gianluca; Ferlenghi, Francesca; Vacondio, Federica; Maccioni, Paola; Colombo, Giancarlo; Mor, Marco; Starowicz, Katarzyna; Di Marzo, Vincenzo; Ligresti, Alessia; Corelli, Federico | - | |
| Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors | 1-gen-2007 | Brizzi, Antonella; Cascio, M. G.; Brizzi, Vittorio; Bisogno, T.; Dinatolo, Maria Teresa; Martinelli, A.; Tuccinardi, T.; Di Marzo, V. | - | |
| Development and characterization of immobilized cannabinoid receptor (CB1/CB2) open tubular column for on-line screening | 1-gen-2011 | Moaddel, R.; Rosenberg, A.; Spelman, K.; Frazier, J.; Frazier, C.; Nocerino, S.; Brizzi, Antonella; Mugnaini, Claudia; Wainer, I. W. | - | |
| Development of 1-(2-aminophenyl)pyrrole-based amides acting as human topoisomerase I inhibitors | 1-gen-2023 | Carullo, Gabriele; Mazzotta, Sarah; Ceramella, Jessica; Iacopetta, Domenico; Ramunno, Anna; Rosano, Camillo; Brizzi, Antonella; Campiani, Giuseppe; Aiello, Francesca; Sinicropi, Maria S | - |