IRIS
6.1 Brevetto
 Distribuzione geografica
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Continente #
NA - Nord America 22.896
EU - Europa 20.833
AS - Asia 9.255
SA - Sud America 1.335
AF - Africa 441
Continente sconosciuto - Info sul continente non disponibili 32
OC - Oceania 31
AN - Antartide 1
Totale 54.824
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Nazione #
US - Stati Uniti d'America 22.500
GB - Regno Unito 8.066
CN - Cina 3.705
SG - Singapore 2.737
RU - Federazione Russa 2.485
IT - Italia 2.437
IE - Irlanda 1.923
UA - Ucraina 1.330
SE - Svezia 1.315
FR - Francia 1.180
BR - Brasile 1.112
DE - Germania 1.044
VN - Vietnam 729
HK - Hong Kong 666
KR - Corea 516
FI - Finlandia 436
CA - Canada 290
IN - India 246
ZA - Sudafrica 178
TR - Turchia 144
ES - Italia 125
CI - Costa d'Avorio 116
NL - Olanda 96
BD - Bangladesh 77
PL - Polonia 77
BE - Belgio 74
JP - Giappone 69
MX - Messico 67
AR - Argentina 63
IQ - Iraq 63
PK - Pakistan 42
EC - Ecuador 41
RO - Romania 38
CZ - Repubblica Ceca 36
ID - Indonesia 33
GR - Grecia 32
EU - Europa 31
CO - Colombia 28
MA - Marocco 28
AU - Australia 26
CL - Cile 25
VE - Venezuela 25
KE - Kenya 24
UZ - Uzbekistan 24
NG - Nigeria 23
SA - Arabia Saudita 23
EG - Egitto 20
IM - Isola di Man 18
JO - Giordania 18
AE - Emirati Arabi Uniti 16
DZ - Algeria 16
AT - Austria 15
MY - Malesia 15
PH - Filippine 14
PY - Paraguay 14
AZ - Azerbaigian 12
IR - Iran 12
LV - Lettonia 12
BO - Bolivia 11
IL - Israele 11
KG - Kirghizistan 11
LB - Libano 11
PA - Panama 11
HR - Croazia 10
HU - Ungheria 10
PE - Perù 10
TN - Tunisia 10
BG - Bulgaria 9
KZ - Kazakistan 9
SN - Senegal 9
LT - Lituania 8
NP - Nepal 8
PT - Portogallo 8
CH - Svizzera 7
ET - Etiopia 7
SI - Slovenia 6
UY - Uruguay 6
AL - Albania 5
BA - Bosnia-Erzegovina 5
HN - Honduras 5
NZ - Nuova Zelanda 5
OM - Oman 5
SK - Slovacchia (Repubblica Slovacca) 5
TH - Thailandia 5
DK - Danimarca 4
GT - Guatemala 4
NI - Nicaragua 4
PS - Palestinian Territory 4
RS - Serbia 4
TW - Taiwan 4
BH - Bahrain 3
CR - Costa Rica 3
KW - Kuwait 3
LK - Sri Lanka 3
MD - Moldavia 3
NO - Norvegia 3
AF - Afghanistan, Repubblica islamica di 2
AM - Armenia 2
AO - Angola 2
BB - Barbados 2
Totale 54.784
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Città #
Dallas 10.077
Southend 7.487
Dublin 1.882
Menlo Park 1.614
Singapore 1.532
Chandler 1.271
Jacksonville 1.102
Beijing 908
San Jose 788
Siena 788
Ashburn 714
Moscow 695
Hefei 688
Santa Clara 660
Hong Kong 649
Ann Arbor 528
Seoul 510
Nanjing 394
Princeton 388
Wilmington 366
The Dalles 317
Woodbridge 266
Los Angeles 239
Helsinki 230
Dearborn 216
Lauterbourg 209
Ho Chi Minh City 207
Munich 201
San Mateo 192
Dong Ket 188
Fairfield 177
Montréal 165
Boardman 161
Johannesburg 156
New York 142
Nanchang 141
Hanoi 129
Rome 126
Abidjan 115
Milan 113
Buffalo 110
Mcallen 110
Düsseldorf 106
Florence 105
São Paulo 99
Shenyang 98
Málaga 96
Bengaluru 91
Izmir 91
Shanghai 90
Lancaster 76
Kunming 75
Hebei 73
Brussels 70
Frankfurt am Main 69
Houston 66
Changsha 61
Redondo Beach 57
Auburn Hills 56
Redwood City 56
Tianjin 55
Philadelphia 52
Toronto 52
Jiaxing 50
Council Bluffs 46
Jinan 46
Orem 45
Tokyo 45
Fremont 44
Hangzhou 44
Mestre 44
Warsaw 44
Guangzhou 43
Zhengzhou 43
Chennai 41
Cambridge 39
Venezia 37
San Francisco 36
Montreal 35
Nuremberg 33
Rio de Janeiro 33
Amsterdam 32
London 31
Stockholm 28
Norwalk 27
Baghdad 26
Dhaka 26
Grünheide 26
Ningbo 26
Turin 26
Da Nang 25
Poplar 25
San Diego 25
Atlanta 24
Naples 24
Timisoara 24
Seattle 23
Brno 22
Chicago 22
Nairobi 22
Totale 39.777
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Nome #
1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF 7.373
Sulfated hyaluronic acid and esters 651
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 486
Ligandi TRPV1 480
Modello molecolare tridimensionale del peplomero del coronavirus della SARS come base razionale per la progettazione di farmaci e kit diagnostici 453
Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto 384
1-aminopyrazole, Verfahren zu deren herstellung und diese Verbindung enthaltende 383
N-ACYLTHIOUREA AND N-ACYLUREA INHIBITORS OF THE HEDGEHOG PROTEIN SIGNALLING PATHWAY 382
New macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors 368
Linear guanidine derivatives, methods of preparation and uses thereof 357
"A method of inhibiting cancer cell growth using a vector expressing pRb2/p130." 354
N-Acylthiourees et N-acylurees inhibiteurs de la voie de signalisation des proteines Hedgehog 354
RADAR OBSTACLE DETECTOR FOR A RAILWAY CROSSING 353
Dérivé de quinolinone 353
N-Acylthourees et N-acylurees inhibiteurs de la voie de signalisation des proteines Hedgehog 350
Gli1 inhibitors and uses thereof 347
Derives substitues en 4 de pyrazolo[3,4-d]pyrimidine et pyrrolo[2,3-d]pyrimidine et utilisations associees 340
" Methods of inhibiting smooth muscle cell proliferation and preventing restenosis with a vector expressing RB2/p130 " 334
Acyl guanidine derivatives modulating the hedgehog protein signaling pathway 328
Derives d'acyl-guanidines modulateurs de la voie de signalisation des proteines hedgehog 327
Systems and methods for treating brain disease using targeted neurostimulation 319
"Peptide inhibitors of cyclin-dependent kinase activity and uses thereof." 317
Metodo e kit per la rivelazione della razza suina cinta senese. 309
"pRb2/p130 Peptide Inhibitors of cdk2 Kinase activity" 305
158. Preparation of analogues of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine as antitubercular agents 298
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 293
"Methods of diagnosis, prognosis and treating breast cancer." 288
"Gene modulation by Rb2/p130 expression." 288
"Methods for determining presence of cancer by analyzing the expression of cyclin-dependent kinase 9 (CDK9) and /or cyclin T1 in lymphoid tissue." 287
"Genetic and epigenetic alterations in the diagnosis and treatment of cancer." 284
Apparecchiatura per la raccolta di materiale biologico o abiologico, in particolare polline 277
"Peptide inhibitors of cyclin-dependent kinase activity and uses thereof." 273
"Methods for the diagnosis and prognosis of cancer." 269
6-Vinyl pyrimidine and pyrimidinone derivatives and the use thereof 268
"Regenerating and enhancing development of muscle tissue." 267
"Determination of Cyclin-Dependent Kinase Inhibitor p27 levels as a prognostic factor in cancer patients." 266
Tetraidropiranil e tetraidrofuranil-eteri con odore floreale. 263
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 261
SISTEMA PER ESEGUIRE IL TRACKING DI UN OGGETTO 261
ANTIBODIES DIRECTED AGAINST THE MYELIN BASIC PROTEIN RECOGNISING AN EPITOPE OF CD64 AND THEIR USE AS IMMUNOSUPPRESSANT 260
Histone Deacetylase Inhibitors-based antibody drug conjugates (ADCs) and use in therapy 259
Supramolecular aggregates as drug carriers on cell expressing receptors for branched Neurotensin 256
Peptidi epitopici immunogenici del CEA da utilizzare nella chemio-immunoterapia del carcinoma del colon-retto e della mammella. 256
DERIVATI FOSFATATI DI POLISACCARIDI E USI DI ESSI 254
N-Acylthiourees et N-acylurees inhibiteurs de la voie de signalisation des proteines hedgehog 254
U1snRNP regulates gene expression and modulates oncogenicity 254
New 4-substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 253
Acido ialuronico solfatato e suoi derivati legati covalentemente a polimeri sintetici per la preparazione di biomateriali e per rivestimento di oggetti biomedicali in campo sanitario e chirurgico 250
Branched peptides for tumor diagnosis and therapy 248
Sistema per guidare un soggetto o utente attraverso un operatore remoto 247
Sistema integrato per la produzione di energia elettrica tramite celle a combustibile alimentate con idrogeno ottenuto da etanolo o altro alcool a seguito di reforming catalitico 246
Antibacterial peptides and analogues thereof 245
Dispositivo da dito personalizzabile con retroazione kinestetica e cutanea 244
NUOVA TERAPIA PER IL TRATTAMENTO DELL'IPERURICEMIA NELLA SINDROME DI LESCH-NYHAN 243
3-Substituted-1,5-diarly-2-alkyl-pyrroles Highly Selective and Orally Effective COX-2 Inhibitors 242
ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE 240
Polymetaphosphate based formulations for therapy of microcrystalline arthropaties 239
Sistema per guidare il passo di un soggetto 238
Novel aryl piperazine derivatives with medical utility 237
Toxin-related antibodies with antimicrobial and antiviral activity 236
Procedimento di marcatura anticontraffazione di prodotti a stampa e relativo sistema” inventori 230
”Tumor Suppressor Protein pRB2, related gene products, and DNA encoding therefor” 229
Antimicrobial peptide, branched forms thereof, and their use in the treatment of bacterial infections 228
Polisaccaridi solfatati 226
COMPOSITIONS FOR TREATING HELICOBACTER PYLORI INFECTION 226
Amidine, Thiourea and Guanidine Derivatives of 2-Aminobenzothiazoles and Aminobenzothiazines, Novel Pharmacological Agents for the Treatment of Neurodegenerative Pathologies 225
A METHOD FOR IN VITRO DIAGNOSIS OF ALLERGY AND RELATED DEVICE 224
ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS. 222
Impianto di cogenerazione a idrogeno, particolarmente per edifici fuori-griglia 221
Branched multimeric peptides for tumor diagnosis and therapy 220
Nuovi Potenti e Selettivi ligandi dei recettori dei cannabinoidi 220
Dispositivo di disinfezione 220
Process for the production of aliskiren 219
TREATMENT OF ALKAPTONURIA AND TYROSINEMIA TYPE 1 219
Detergente emolliente per l'igiene palpebrale e perioculare. 218
Aryl triazole compounds with antitumoural activity 218
Pyrrole compounds as inibitors of mycobacteria, synthesis thereof and intermediates thereto 213
”Tumor Suppressor Protein pRB2, related gene products, and DNA encoding therefor” 205
Nitroesteri di 1,5-Diaril-2-alchil-pirroli-3-sostituiti,Inibitori Selettivi di COX-2 e Donatori di Ossido Nitrico 205
Procedimento per il trattamento delle acque reflue da lavorazione degli oli di oliva e simili per l'ottenimento, per via naturale, di antiossidanti per impieghi farmaceutico, cosmetico ed alimentare. 205
LINEAR AND CYCLIC GUANIDINE DERIVATIVES, METHOD OF PREPARATION AND USES THEREOF 204
“Diagnostic and therapeutic tools for X-linked mental retardation syndrome “ 204
Three electrode electrochemical amperometric sensor 201
Preparation of new macrocyclic amidinourea derivatives as chitinase inhibitors 201
Coloranti sostantivi fotostabili per la colorazione semipermanente dei capelli. 200
NOVEL 4-AMINO-QUINOLINE DERIVATIVES USEFUL AS ANTI-MALARIA DRUGS 200
Lampada igienizzante 199
Fos regulated genes and use thereof 198
Virosoma dell'influenza immunoricostituito (IRIV) contenente il gene per CD40L come immunoprotettore tumorale CEA-specifico e usi immunogenici di esso. 198
Quinolinone derivatives 197
Treatment of alkaptonuria and tyrosinemia type I 197
Procedimento per la produzione dell’esametildi 196
Derivati 4-sostituiti della 1-(2-cloro-2-feniletil)-1H-pirazolo[3,4-d]pirimidina e loro usi. 195
Misuratore di Campo elettrico 194
marcatore biologico per l'atrofia muscolare spinale. 194
Procedimento per la conversione regiospecifica di ossirani in alcoli primari bifunzionali 193
Acyl guanidine derivatives modulating the hedgehog protein signaling pathway 193
Method and system for fetal weight estimation 193
COMPOUNDS WITH ATYPICAL ANTIPSYCHOTIC ACTIVITY 192
Neurotensin-derived branched peptides and uses thereof 192
Totale 33.685
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021976 0 0 0 0 0 0 0 0 0 207 272 497
2021/20223.906 302 607 356 225 136 320 74 106 260 326 526 668
2022/20234.623 326 357 588 625 459 912 81 382 441 152 207 93
2023/20243.232 142 49 244 134 134 686 1.233 207 12 69 47 275
2024/20256.023 205 419 509 307 575 290 139 290 504 250 607 1.928
2025/202620.151 1.168 4.172 7.286 1.528 2.246 521 1.563 448 400 819 0 0
Totale 55.192