IRIS
6.1 Brevetto
 Distribuzione geografica
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Continente #
EU - Europa 17.826
NA - Nord America 9.409
AS - Asia 2.761
AF - Africa 133
SA - Sud America 32
Continente sconosciuto - Info sul continente non disponibili 31
OC - Oceania 24
AN - Antartide 1
Totale 30.217
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Nazione #
US - Stati Uniti d'America 9.177
GB - Regno Unito 7.915
IT - Italia 2.080
IE - Irlanda 1.919
CN - Cina 1.903
UA - Ucraina 1.315
SE - Svezia 1.289
DE - Germania 899
FR - Francia 854
RU - Federazione Russa 789
SG - Singapore 389
FI - Finlandia 329
CA - Canada 223
VN - Vietnam 191
CI - Costa d'Avorio 111
TR - Turchia 111
ES - Italia 110
BE - Belgio 73
HK - Hong Kong 48
RO - Romania 36
CZ - Repubblica Ceca 34
NL - Olanda 33
PL - Polonia 33
EU - Europa 31
GR - Grecia 30
JP - Giappone 28
IN - India 27
AU - Australia 21
IM - Isola di Man 18
BR - Brasile 16
HR - Croazia 10
HU - Ungheria 10
IR - Iran 10
EG - Egitto 8
LV - Lettonia 8
CL - Cile 7
BG - Bulgaria 6
AT - Austria 5
CO - Colombia 5
ID - Indonesia 5
KR - Corea 5
PA - Panama 5
PH - Filippine 5
PT - Portogallo 5
SI - Slovenia 5
IL - Israele 4
MA - Marocco 4
MY - Malesia 4
SK - Slovacchia (Repubblica Slovacca) 4
TN - Tunisia 4
TW - Taiwan 4
CH - Svizzera 3
DK - Danimarca 3
LT - Lituania 3
NZ - Nuova Zelanda 3
PK - Pakistan 3
AE - Emirati Arabi Uniti 2
AF - Afghanistan, Repubblica islamica di 2
CY - Cipro 2
EC - Ecuador 2
EE - Estonia 2
KG - Kirghizistan 2
LK - Sri Lanka 2
NG - Nigeria 2
RS - Serbia 2
TH - Thailandia 2
ZA - Sudafrica 2
AM - Armenia 1
AR - Argentina 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BD - Bangladesh 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
GE - Georgia 1
GS - Georgia del Sud e Isole Sandwich Australi 1
JO - Giordania 1
KH - Cambogia 1
KW - Kuwait 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LU - Lussemburgo 1
MD - Moldavia 1
MK - Macedonia 1
MS - Montserrat 1
MX - Messico 1
PY - Paraguay 1
SA - Arabia Saudita 1
SC - Seychelles 1
UZ - Uzbekistan 1
Totale 30.217
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Città #
Southend 7.487
Dublin 1.878
Menlo Park 1.614
Chandler 1.271
Jacksonville 1.101
Siena 770
Ann Arbor 528
Beijing 494
Ashburn 492
Nanjing 393
Princeton 388
Wilmington 366
Singapore 271
Woodbridge 266
Dearborn 216
San Mateo 192
Dong Ket 188
Fairfield 177
Montréal 165
Boardman 161
Munich 154
Helsinki 147
Nanchang 141
Moscow 127
Abidjan 111
Mcallen 110
Málaga 96
Shenyang 95
Rome 94
Düsseldorf 93
Izmir 90
Shanghai 80
Lancaster 76
Hebei 73
Kunming 73
Florence 72
Brussels 69
New York 57
Auburn Hills 56
Redwood City 56
Changsha 50
Milan 50
Philadelphia 50
Jiaxing 49
Tianjin 49
Houston 48
Fremont 44
Mestre 44
Jinan 43
Los Angeles 43
Hong Kong 41
Cambridge 39
Venezia 37
Zhengzhou 37
Hangzhou 34
Toronto 33
Frankfurt am Main 31
Hefei 29
San Francisco 28
Guangzhou 27
Norwalk 27
Grünheide 26
Ningbo 25
Timisoara 24
San Diego 23
Brno 22
Taizhou 22
Seattle 20
Douglas 18
Gdynia 16
Naples 16
Paris 14
Washington 14
Amsterdam 13
Changchun 13
Dallas 13
Lanzhou 13
Ottawa 13
Turin 13
Fuzhou 12
Kansas City 12
London 11
Santa Clara 11
Bologna 10
Calenzano 10
Edinburgh 10
Zagreb 10
Besançon 9
Melbourne 9
Nashville 9
Parma 9
Poplar 9
Catania 8
Chicago 8
Haikou 8
Messina 8
Monsummano Terme 8
Prato 8
Riga 8
Saronno 8
Totale 21.634
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Nome #
Sulfated hyaluronic acid and esters 595
Modello molecolare tridimensionale del peplomero del coronavirus della SARS come base razionale per la progettazione di farmaci e kit diagnostici 378
Ligandi TRPV1 351
1-aminopyrazole, Verfahren zu deren herstellung und diese Verbindung enthaltende 293
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 255
N-ACYLTHIOUREA AND N-ACYLUREA INHIBITORS OF THE HEDGEHOG PROTEIN SIGNALLING PATHWAY 245
Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto 234
Gli1 inhibitors and uses thereof 227
N-Acylthourees et N-acylurees inhibiteurs de la voie de signalisation des proteines Hedgehog 224
Dérivé de quinolinone 221
RADAR OBSTACLE DETECTOR FOR A RAILWAY CROSSING 220
1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF 220
Linear guanidine derivatives, methods of preparation and uses thereof 217
New macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors 215
Derives substitues en 4 de pyrazolo[3,4-d]pyrimidine et pyrrolo[2,3-d]pyrimidine et utilisations associees 208
N-Acylthiourees et N-acylurees inhibiteurs de la voie de signalisation des proteines Hedgehog 207
Acyl guanidine derivatives modulating the hedgehog protein signaling pathway 197
Sistema integrato per la produzione di energia elettrica tramite celle a combustibile alimentate con idrogeno ottenuto da etanolo o altro alcool a seguito di reforming catalitico 197
Supramolecular aggregates as drug carriers on cell expressing receptors for branched Neurotensin 194
DERIVATI FOSFATATI DI POLISACCARIDI E USI DI ESSI 191
Toxin-related antibodies with antimicrobial and antiviral activity 190
Derives d'acyl-guanidines modulateurs de la voie de signalisation des proteines hedgehog 188
Histone Deacetylase Inhibitors-based antibody drug conjugates (ADCs) and use in therapy 188
New 4-substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 187
Peptidi epitopici immunogenici del CEA da utilizzare nella chemio-immunoterapia del carcinoma del colon-retto e della mammella. 186
"A method of inhibiting cancer cell growth using a vector expressing pRb2/p130." 186
Metodo e kit per la rivelazione della razza suina cinta senese. 183
Systems and methods for treating brain disease using targeted neurostimulation 182
ANTIBODIES DIRECTED AGAINST THE MYELIN BASIC PROTEIN RECOGNISING AN EPITOPE OF CD64 AND THEIR USE AS IMMUNOSUPPRESSANT 181
U1snRNP regulates gene expression and modulates oncogenicity 181
Tetraidropiranil e tetraidrofuranil-eteri con odore floreale. 175
Procedimento di marcatura anticontraffazione di prodotti a stampa e relativo sistema” inventori 172
Branched peptides for tumor diagnosis and therapy 172
N-Acylthiourees et N-acylurees inhibiteurs de la voie de signalisation des proteines hedgehog 172
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 169
158. Preparation of analogues of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine as antitubercular agents 169
Sistema per guidare un soggetto o utente attraverso un operatore remoto 169
" Methods of inhibiting smooth muscle cell proliferation and preventing restenosis with a vector expressing RB2/p130 " 167
”Tumor Suppressor Protein pRB2, related gene products, and DNA encoding therefor” 167
A METHOD FOR IN VITRO DIAGNOSIS OF ALLERGY AND RELATED DEVICE 164
TREATMENT OF ALKAPTONURIA AND TYROSINEMIA TYPE 1 162
Polisaccaridi solfatati 161
Treatment of alkaptonuria and tyrosinemia type I 158
ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE 157
null 157
Nitroesteri di 1,5-Diaril-2-alchil-pirroli-3-sostituiti,Inibitori Selettivi di COX-2 e Donatori di Ossido Nitrico 156
Detergente emolliente per l'igiene palpebrale e perioculare. 155
Pyrrole compounds as inibitors of mycobacteria, synthesis thereof and intermediates thereto 155
“Diagnostic and therapeutic tools for X-linked mental retardation syndrome “ 155
Impianto di cogenerazione a idrogeno, particolarmente per edifici fuori-griglia 154
COMPOSITIONS FOR TREATING HELICOBACTER PYLORI INFECTION 154
Apparecchiatura per la raccolta di materiale biologico o abiologico, in particolare polline 153
ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS. 153
NUOVA TERAPIA PER IL TRATTAMENTO DELL'IPERURICEMIA NELLA SINDROME DI LESCH-NYHAN 153
”Tumor Suppressor Protein pRB2, related gene products, and DNA encoding therefor” 150
null 150
Multitarget hedgehog pathway inhibitors and uses thereof 150
Antibacterial peptides and analogues thereof 149
3-Substituted-1,5-diarly-2-alkyl-pyrroles Highly Selective and Orally Effective COX-2 Inhibitors 149
Acyl guanidine derivatives modulating the hedgehog protein signaling pathway 148
Acyl guanidine derivatives modulating the hedgehog protein signaling pathway 147
Process for the production of aliskiren 146
Antimicrobial peptide, branched forms thereof, and their use in the treatment of bacterial infections 146
Nuovi Potenti e Selettivi ligandi dei recettori dei cannabinoidi 145
Procedimento per il trattamento delle acque reflue da lavorazione degli oli di oliva e simili per l'ottenimento, per via naturale, di antiossidanti per impieghi farmaceutico, cosmetico ed alimentare. 145
Novel aryl piperazine derivatives with medical utility 144
"pRb2/p130 Peptide Inhibitors of cdk2 Kinase activity" 144
Three electrode electrochemical amperometric sensor 144
Polymetaphosphate based formulations for therapy of microcrystalline arthropaties 144
Quinolinone derivatives 144
marcatore biologico per l'atrofia muscolare spinale. 144
Branched multimeric peptides for tumor diagnosis and therapy 142
Aryl triazole compounds with antitumoural activity 142
Virosoma dell'influenza immunoricostituito (IRIV) contenente il gene per CD40L come immunoprotettore tumorale CEA-specifico e usi immunogenici di esso. 139
null 138
Procedimento per la produzione dell’esametildi 137
Preparation of new macrocyclic amidinourea derivatives as chitinase inhibitors 137
null 137
Method and device for measurement of magnetic induction 137
Amidine, Thiourea and Guanidine Derivatives of 2-Aminobenzothiazoles and Aminobenzothiazines, Novel Pharmacological Agents for the Treatment of Neurodegenerative Pathologies 137
null 137
"Gene modulation by Rb2/p130 expression." 136
"Peptide inhibitors of cyclin-dependent kinase activity and uses thereof." 136
Misuratore di Campo elettrico 135
Procedimento per la conversione regiospecifica di ossirani in alcoli primari bifunzionali 135
COMPOSTO BASEADO EM ACIDO HIALURONICO, SAL DE SODIO, PROCESSO PARA PREPARAR UM COMPOSTO OU UM SEU SAL, COMPOSIQAO FARMACEUTICA, PRODUTO MEDICINAL E DISPOSITIVO MEDICO PARA USO HUMANO OU VETERINARIO, E, USO DE COMPOSTO OU DE SEU SAL 135
"Genetic and epigenetic alterations in the diagnosis and treatment of cancer." 133
"Methods for the diagnosis and prognosis of cancer." 133
Heterotricyclic Amide Derivatives as Neurokinin-1 (NK1) Receptor Ligands 132
Coloranti sostantivi fotostabili per la colorazione semipermanente dei capelli. 132
6-Vinyl pyrimidine and pyrimidinone derivatives and the use thereof 132
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 132
"Peptide inhibitors of cyclin-dependent kinase activity and uses thereof." 132
COMPOUNDS WITH ATYPICAL ANTIPSYCHOTIC ACTIVITY 131
Acido ialuronico solfatato e suoi derivati legati covalentemente a polimeri sintetici per la preparazione di biomateriali e per rivestimento di oggetti biomedicali in campo sanitario e chirurgico 131
"Methods for determining presence of cancer by analyzing the expression of cyclin-dependent kinase 9 (CDK9) and /or cyclin T1 in lymphoid tissue." 131
Method and system for fetal weight estimation 130
DERIVATI 4-SOSTITUITI DELLA 1-(2-CLORO-2-FENILETIL)-1H-PIRAZOLO[3,4-D]PIRIMIDINA E LORO USI. 129
Proteine, Fh-binding protein of Streptococcus pneumoniae 129
Prokineticin 1 receptor agonists and their uses 129
Totale 17.205
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.566 0 0 0 0 184 380 283 664 141 527 138 249
2020/20213.709 112 356 27 247 89 738 260 484 420 207 272 497
2021/20223.906 302 607 356 225 136 320 74 106 260 326 526 668
2022/20234.623 326 357 588 625 459 912 81 382 441 152 207 93
2023/20243.232 142 49 244 134 134 686 1.233 207 12 69 47 275
2024/20251.547 205 419 509 307 107 0 0 0 0 0 0 0
Totale 30.565