IRIS
6.1 Brevetto
 Distribuzione geografica
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Continente #
NA - Nord America 21.625
EU - Europa 20.240
AS - Asia 7.980
SA - Sud America 1.241
AF - Africa 240
Continente sconosciuto - Info sul continente non disponibili 32
OC - Oceania 29
AN - Antartide 1
Totale 51.388
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Nazione #
US - Stati Uniti d'America 21.258
GB - Regno Unito 8.017
CN - Cina 3.422
RU - Federazione Russa 2.483
IT - Italia 2.349
SG - Singapore 2.308
IE - Irlanda 1.921
UA - Ucraina 1.325
SE - Svezia 1.310
BR - Brasile 1.057
DE - Germania 1.010
FR - Francia 884
HK - Hong Kong 607
KR - Corea 515
VN - Vietnam 416
FI - Finlandia 364
CA - Canada 279
IN - India 196
TR - Turchia 139
ES - Italia 123
CI - Costa d'Avorio 116
NL - Olanda 80
BE - Belgio 74
PL - Polonia 67
BD - Bangladesh 58
JP - Giappone 57
AR - Argentina 55
MX - Messico 54
IQ - Iraq 41
CZ - Repubblica Ceca 36
RO - Romania 36
EC - Ecuador 35
ZA - Sudafrica 35
EU - Europa 31
GR - Grecia 31
PK - Pakistan 28
AU - Australia 24
MA - Marocco 24
ID - Indonesia 22
VE - Venezuela 22
CO - Colombia 21
IM - Isola di Man 18
UZ - Uzbekistan 18
CL - Cile 16
EG - Egitto 16
AT - Austria 15
KE - Kenya 15
JO - Giordania 14
AE - Emirati Arabi Uniti 13
SA - Arabia Saudita 13
LV - Lettonia 12
AZ - Azerbaigian 11
IR - Iran 11
PA - Panama 11
PY - Paraguay 11
HR - Croazia 10
HU - Ungheria 10
KG - Kirghizistan 10
TN - Tunisia 10
BG - Bulgaria 9
BO - Bolivia 9
DZ - Algeria 9
IL - Israele 9
LB - Libano 9
PE - Perù 9
PH - Filippine 9
MY - Malesia 8
LT - Lituania 7
PT - Portogallo 7
UY - Uruguay 6
BA - Bosnia-Erzegovina 5
KZ - Kazakistan 5
NZ - Nuova Zelanda 5
SI - Slovenia 5
SK - Slovacchia (Repubblica Slovacca) 5
SN - Senegal 5
CH - Svizzera 4
DK - Danimarca 4
GT - Guatemala 4
HN - Honduras 4
NI - Nicaragua 4
NP - Nepal 4
PS - Palestinian Territory 4
RS - Serbia 4
TH - Thailandia 4
TW - Taiwan 4
AL - Albania 3
CR - Costa Rica 3
LK - Sri Lanka 3
NO - Norvegia 3
OM - Oman 3
AF - Afghanistan, Repubblica islamica di 2
AM - Armenia 2
BN - Brunei Darussalam 2
BS - Bahamas 2
BW - Botswana 2
CY - Cipro 2
DO - Repubblica Dominicana 2
EE - Estonia 2
GE - Georgia 2
Totale 51.358
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Città #
Dallas 10.072
Southend 7.487
Dublin 1.880
Menlo Park 1.614
Singapore 1.288
Chandler 1.271
Jacksonville 1.102
Beijing 904
Siena 784
Moscow 695
Ashburn 680
Santa Clara 643
Hong Kong 599
Hefei 575
Ann Arbor 528
Seoul 510
Nanjing 394
Princeton 388
Wilmington 366
Woodbridge 266
Dearborn 216
Los Angeles 206
Munich 201
San Mateo 192
Dong Ket 188
Fairfield 177
Montréal 165
Boardman 161
Helsinki 158
Nanchang 141
Rome 119
New York 117
Abidjan 115
Mcallen 110
Buffalo 108
Düsseldorf 106
The Dalles 104
Milan 99
Shenyang 98
Florence 96
Málaga 96
Ho Chi Minh City 92
São Paulo 92
Izmir 91
Bengaluru 90
Shanghai 86
Lancaster 76
Kunming 75
Hebei 73
Brussels 70
Houston 65
Changsha 61
Redondo Beach 57
Auburn Hills 56
Redwood City 56
Tianjin 53
Philadelphia 52
Jiaxing 49
Toronto 48
Jinan 46
Fremont 44
Hangzhou 44
Mestre 44
Frankfurt am Main 42
Zhengzhou 42
Guangzhou 41
Hanoi 40
Cambridge 39
Venezia 37
San Francisco 36
Tokyo 36
Council Bluffs 35
Warsaw 35
Rio de Janeiro 32
Montreal 29
Nuremberg 29
Norwalk 27
Grünheide 26
London 26
Ningbo 26
Chennai 25
Poplar 24
San Diego 24
Stockholm 24
Timisoara 24
Dhaka 23
Seattle 23
Brno 22
Chicago 22
Naples 22
Taizhou 22
Turin 22
Turku 22
Amsterdam 21
Atlanta 19
Belo Horizonte 19
Brooklyn 19
Douglas 18
Washington 18
Curitiba 17
Totale 37.447
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Nome #
1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF 7.353
Sulfated hyaluronic acid and esters 641
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 463
Ligandi TRPV1 455
Modello molecolare tridimensionale del peplomero del coronavirus della SARS come base razionale per la progettazione di farmaci e kit diagnostici 438
1-aminopyrazole, Verfahren zu deren herstellung und diese Verbindung enthaltende 364
Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto 364
N-ACYLTHIOUREA AND N-ACYLUREA INHIBITORS OF THE HEDGEHOG PROTEIN SIGNALLING PATHWAY 356
New macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors 349
N-Acylthiourees et N-acylurees inhibiteurs de la voie de signalisation des proteines Hedgehog 341
"A method of inhibiting cancer cell growth using a vector expressing pRb2/p130." 340
Linear guanidine derivatives, methods of preparation and uses thereof 340
N-Acylthourees et N-acylurees inhibiteurs de la voie de signalisation des proteines Hedgehog 337
Dérivé de quinolinone 333
Gli1 inhibitors and uses thereof 327
Derives substitues en 4 de pyrazolo[3,4-d]pyrimidine et pyrrolo[2,3-d]pyrimidine et utilisations associees 327
RADAR OBSTACLE DETECTOR FOR A RAILWAY CROSSING 320
" Methods of inhibiting smooth muscle cell proliferation and preventing restenosis with a vector expressing RB2/p130 " 316
Acyl guanidine derivatives modulating the hedgehog protein signaling pathway 308
"Peptide inhibitors of cyclin-dependent kinase activity and uses thereof." 304
Derives d'acyl-guanidines modulateurs de la voie de signalisation des proteines hedgehog 299
Systems and methods for treating brain disease using targeted neurostimulation 297
"pRb2/p130 Peptide Inhibitors of cdk2 Kinase activity" 291
Metodo e kit per la rivelazione della razza suina cinta senese. 290
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 275
"Methods of diagnosis, prognosis and treating breast cancer." 275
"Gene modulation by Rb2/p130 expression." 275
158. Preparation of analogues of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine as antitubercular agents 274
"Methods for determining presence of cancer by analyzing the expression of cyclin-dependent kinase 9 (CDK9) and /or cyclin T1 in lymphoid tissue." 271
"Genetic and epigenetic alterations in the diagnosis and treatment of cancer." 259
Apparecchiatura per la raccolta di materiale biologico o abiologico, in particolare polline 256
"Peptide inhibitors of cyclin-dependent kinase activity and uses thereof." 256
"Regenerating and enhancing development of muscle tissue." 255
"Methods for the diagnosis and prognosis of cancer." 254
"Determination of Cyclin-Dependent Kinase Inhibitor p27 levels as a prognostic factor in cancer patients." 253
ANTIBODIES DIRECTED AGAINST THE MYELIN BASIC PROTEIN RECOGNISING AN EPITOPE OF CD64 AND THEIR USE AS IMMUNOSUPPRESSANT 252
Histone Deacetylase Inhibitors-based antibody drug conjugates (ADCs) and use in therapy 249
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 247
Supramolecular aggregates as drug carriers on cell expressing receptors for branched Neurotensin 245
Tetraidropiranil e tetraidrofuranil-eteri con odore floreale. 244
6-Vinyl pyrimidine and pyrimidinone derivatives and the use thereof 242
DERIVATI FOSFATATI DI POLISACCARIDI E USI DI ESSI 241
New 4-substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof 240
Peptidi epitopici immunogenici del CEA da utilizzare nella chemio-immunoterapia del carcinoma del colon-retto e della mammella. 238
U1snRNP regulates gene expression and modulates oncogenicity 238
Sistema integrato per la produzione di energia elettrica tramite celle a combustibile alimentate con idrogeno ottenuto da etanolo o altro alcool a seguito di reforming catalitico 236
SISTEMA PER ESEGUIRE IL TRACKING DI UN OGGETTO 235
Antibacterial peptides and analogues thereof 234
Dispositivo da dito personalizzabile con retroazione kinestetica e cutanea 232
Sistema per guidare un soggetto o utente attraverso un operatore remoto 231
Branched peptides for tumor diagnosis and therapy 229
Acido ialuronico solfatato e suoi derivati legati covalentemente a polimeri sintetici per la preparazione di biomateriali e per rivestimento di oggetti biomedicali in campo sanitario e chirurgico 229
N-Acylthiourees et N-acylurees inhibiteurs de la voie de signalisation des proteines hedgehog 227
Polymetaphosphate based formulations for therapy of microcrystalline arthropaties 226
NUOVA TERAPIA PER IL TRATTAMENTO DELL'IPERURICEMIA NELLA SINDROME DI LESCH-NYHAN 225
Toxin-related antibodies with antimicrobial and antiviral activity 225
ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE 222
Procedimento di marcatura anticontraffazione di prodotti a stampa e relativo sistema” inventori 221
Novel aryl piperazine derivatives with medical utility 217
Polisaccaridi solfatati 214
A METHOD FOR IN VITRO DIAGNOSIS OF ALLERGY AND RELATED DEVICE 214
”Tumor Suppressor Protein pRB2, related gene products, and DNA encoding therefor” 213
ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS. 211
Impianto di cogenerazione a idrogeno, particolarmente per edifici fuori-griglia 210
Antimicrobial peptide, branched forms thereof, and their use in the treatment of bacterial infections 210
Amidine, Thiourea and Guanidine Derivatives of 2-Aminobenzothiazoles and Aminobenzothiazines, Novel Pharmacological Agents for the Treatment of Neurodegenerative Pathologies 209
3-Substituted-1,5-diarly-2-alkyl-pyrroles Highly Selective and Orally Effective COX-2 Inhibitors 208
TREATMENT OF ALKAPTONURIA AND TYROSINEMIA TYPE 1 208
COMPOSITIONS FOR TREATING HELICOBACTER PYLORI INFECTION 207
Sistema per guidare il passo di un soggetto 207
Detergente emolliente per l'igiene palpebrale e perioculare. 206
Branched multimeric peptides for tumor diagnosis and therapy 206
Dispositivo di disinfezione 206
Aryl triazole compounds with antitumoural activity 205
Pyrrole compounds as inibitors of mycobacteria, synthesis thereof and intermediates thereto 201
Nuovi Potenti e Selettivi ligandi dei recettori dei cannabinoidi 199
Process for the production of aliskiren 198
”Tumor Suppressor Protein pRB2, related gene products, and DNA encoding therefor” 195
Nitroesteri di 1,5-Diaril-2-alchil-pirroli-3-sostituiti,Inibitori Selettivi di COX-2 e Donatori di Ossido Nitrico 193
Three electrode electrochemical amperometric sensor 193
Treatment of alkaptonuria and tyrosinemia type I 192
“Diagnostic and therapeutic tools for X-linked mental retardation syndrome “ 190
Coloranti sostantivi fotostabili per la colorazione semipermanente dei capelli. 188
Preparation of new macrocyclic amidinourea derivatives as chitinase inhibitors 188
Acyl guanidine derivatives modulating the hedgehog protein signaling pathway 185
LINEAR AND CYCLIC GUANIDINE DERIVATIVES, METHOD OF PREPARATION AND USES THEREOF 184
Quinolinone derivatives 184
marcatore biologico per l'atrofia muscolare spinale. 183
Fos regulated genes and use thereof 183
Virosoma dell'influenza immunoricostituito (IRIV) contenente il gene per CD40L come immunoprotettore tumorale CEA-specifico e usi immunogenici di esso. 182
Lampada igienizzante 182
COMPOUNDS WITH ATYPICAL ANTIPSYCHOTIC ACTIVITY 181
Procedimento per il trattamento delle acque reflue da lavorazione degli oli di oliva e simili per l'ottenimento, per via naturale, di antiossidanti per impieghi farmaceutico, cosmetico ed alimentare. 181
Multitarget hedgehog pathway inhibitors and uses thereof 181
NOVEL 4-AMINO-QUINOLINE DERIVATIVES USEFUL AS ANTI-MALARIA DRUGS 180
Derivati 4-sostituiti della 1-(2-cloro-2-feniletil)-1H-pirazolo[3,4-d]pirimidina e loro usi. 179
Misuratore di Campo elettrico 179
Procedimento per la conversione regiospecifica di ossirani in alcoli primari bifunzionali 179
Elemento prensile robotico indossabile da un soggetto per ausilio alla presa 179
Neurotensin-derived branched peptides and uses thereof 178
Totale 32.052
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.878 0 0 0 0 0 738 260 484 420 207 272 497
2021/20223.906 302 607 356 225 136 320 74 106 260 326 526 668
2022/20234.623 326 357 588 625 459 912 81 382 441 152 207 93
2023/20243.232 142 49 244 134 134 686 1.233 207 12 69 47 275
2024/20256.023 205 419 509 307 575 290 139 290 504 250 607 1.928
2025/202616.715 1.168 4.172 7.286 1.528 2.246 315 0 0 0 0 0 0
Totale 51.756