The present invention concerns novel pyrrole compounds, derivatives of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine (BM212). The invention concerns the use of the described compounds as antitubercular agents and a process to obtain intermediates and final compounds. The compounds of the invention are found to be more active and much less toxic than previously known compounds.
Biava, M., Porretta, G.c., Pompei, R., Botta, M., Manetti, F., De Logu, A. (2013)Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto. . Brevetto No. EP2195289B1.
Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto
BOTTA, MAURIZIO;MANETTI, FABRIZIO;
2013-01-01
Abstract
The present invention concerns novel pyrrole compounds, derivatives of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine (BM212). The invention concerns the use of the described compounds as antitubercular agents and a process to obtain intermediates and final compounds. The compounds of the invention are found to be more active and much less toxic than previously known compounds.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/1011101
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo