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EnglishAnti-idiotypic antibodies which recognise the idiotope of an antibody specific for a yeast killer toxin possess microbicidal activity. Fragments (e.g. decapeptides) of these anti-idiotypic antibodies, particularly those comprising CDR residues, also show microbicidal activity, as do peptides having 5 the same sequence but composed of D-amino acids, or including amino acid substitutions. Peptidomimetics of these microbicidal polypeptides are also provided. Antiviral activity is also seen.
Luciano, P., Antonio, C., Bracci, L., Neri, P., & Lozzi, L. (2003)Toxin-related antibodies with antimicrobial and antiviral activity. . Brevetto No. US 7722876 B2.
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| Titolo: | Toxin-related antibodies with antimicrobial and antiviral activity |
| Autori: | |
| Anno: | 2003 |
| Citazione: | Luciano, P., Antonio, C., Bracci, L., Neri, P., & Lozzi, L. (2003)Toxin-related antibodies with antimicrobial and antiviral activity. . Brevetto No. US 7722876 B2. |
| Abstract: | Anti-idiotypic antibodies which recognise the idiotope of an antibody specific for a yeast killer toxin possess microbicidal activity. Fragments (e.g. decapeptides) of these anti-idiotypic antibodies, particularly those comprising CDR residues, also show microbicidal activity, as do peptides having 5 the same sequence but composed of D-amino acids, or including amino acid substitutions. Peptidomimetics of these microbicidal polypeptides are also provided. Antiviral activity is also seen. |
| Handle: | http://hdl.handle.net/11365/996223 |
| Appare nelle tipologie: | 6.1 Brevetto |
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http://hdl.handle.net/11365/996223
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