IRIS
MORI, MATTIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.642
EU - Europa 3.929
AS - Asia 464
SA - Sud America 8
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 7
AF - Africa 4
Totale 10.061
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Nazione #
US - Stati Uniti d'America 5.629
GB - Regno Unito 1.102
IE - Irlanda 1.008
IT - Italia 535
SE - Svezia 332
CN - Cina 317
UA - Ucraina 308
FR - Francia 294
DE - Germania 159
FI - Finlandia 83
VN - Vietnam 62
ES - Italia 39
TR - Turchia 28
BE - Belgio 17
PL - Polonia 13
CA - Canada 12
IN - India 11
IR - Iran 9
JP - Giappone 9
BG - Bulgaria 8
EU - Europa 7
NL - Olanda 7
AU - Australia 6
CH - Svizzera 6
SG - Singapore 5
HK - Hong Kong 4
ID - Indonesia 4
AE - Emirati Arabi Uniti 3
BR - Brasile 3
EG - Egitto 3
PT - Portogallo 3
SA - Arabia Saudita 3
CY - Cipro 2
DK - Danimarca 2
EC - Ecuador 2
GR - Grecia 2
AM - Armenia 1
AT - Austria 1
BD - Bangladesh 1
CL - Cile 1
CO - Colombia 1
CZ - Repubblica Ceca 1
DO - Repubblica Dominicana 1
EE - Estonia 1
IM - Isola di Man 1
JO - Giordania 1
LK - Sri Lanka 1
LV - Lettonia 1
MA - Marocco 1
MD - Moldavia 1
MK - Macedonia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PE - Perù 1
PK - Pakistan 1
RO - Romania 1
RU - Federazione Russa 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TJ - Tagikistan 1
Totale 10.061
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Città #
Southend 1.012
Dublin 1.003
Fairfield 940
Ashburn 565
Woodbridge 476
Seattle 413
Chandler 353
Wilmington 348
Houston 336
Cambridge 328
Jacksonville 219
Ann Arbor 207
Menlo Park 201
Princeton 200
Siena 196
San Mateo 97
Beijing 90
New York 73
San Diego 67
Nanjing 65
Dong Ket 62
Redwood City 60
Helsinki 53
Boardman 46
Fremont 39
Milan 31
Rome 29
London 27
Izmir 24
Nanchang 22
Shanghai 22
Florence 21
Salamanca 21
Norwalk 18
Shenyang 18
Brussels 17
Dearborn 15
Phoenix 15
Jinan 14
Málaga 13
San Francisco 12
Düsseldorf 11
Venezia 10
Changsha 9
Hebei 9
Kunming 8
Sofia 8
Toronto 8
Guangzhou 7
Jiaxing 7
Kilburn 7
Hounslow 6
Ningbo 6
Padova 6
Pisa 6
Taizhou 6
Tianjin 6
Bonndorf 5
Perugia 5
Arezzo 4
Bagno A Ripoli 4
Bologna 4
Jakarta 4
Los Angeles 4
Parma 4
Tokyo 4
Zanjan 4
Zhengzhou 4
Berlin 3
Brescia 3
Cairo 3
Dubai 3
Esslingen am Neckar 3
Falkenstein 3
Fort Worth 3
Fuzhou 3
Genoa 3
Genova 3
Haikou 3
Hangzhou 3
Hong Kong 3
Islington 3
Melbourne 3
Naples 3
Novara 3
Porto 3
Prescot 3
Reggio Nell'emilia 3
Riyadh 3
Southwark 3
Turin 3
Wandsworth 3
Washington 3
Bari 2
Boston 2
Carpi 2
Changchun 2
Chiswick 2
Cittadella 2
Copenhagen 2
Totale 8.023
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Nome #
Structure, function, involvement in diseases and targeting of 14-3-3 proteins: An Update 208
Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02 201
Potent and selective carboxylic acid inhibitors of tumor-associated carbonic anhydrases IX and XII 189
Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains 184
Molecular insights to the bioactive form of BV02, a reference inhibitor of 14-3-3σ protein-protein interactions 183
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors 181
In Memory of Maurizio Botta: His Contribution to the Development of Computer-Aided Drug Design 170
Differentially activated Src kinase in chemo-naive human primary osteosarcoma cells and effects of a Src kinase inhibitor 169
Discovery of in vitro antitubercular agents through in silico ligand-based approaches 166
Tautomers of a Fluorescent G Surrogate and Their Distinct Photophysics Provide Additional Information Channels 162
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3s case 161
Discovery of 14-3-3 Protein-Protein Interaction Inhibitors that Sensitize Multidrug-Resistant Cancer Cells to Doxorubicin and the Akt Inhibitor GSK690693 154
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors 146
Structure Prediction and Validation of the ERK8 Kinase Domain 142
Multitarget hedgehog pathway inhibitors and uses thereof 142
A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors 140
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 138
Small molecules modulation of 14-3-3 protein–protein interactions 136
Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein 136
Predicting the binding mode of known NCp7 inhibitors to facilitate the design of novel modulators 129
Mycobacterial carbonic anhydrase inhibition with phenolic acids and esters: kinetic and computational investigations 128
Naturally occurring Diels-Alder-type adducts from Morus nigra as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B 128
Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor. 127
Molecular Dynamics and DFT Study on HIV-1 Nucleocapsid Protein-7 in Complex with Viral Genome. 122
Targeting Protein-Protein and Protein-Nucleic Acid Interactions for Anti-HIV Therapy 122
Free energy profile and kinetics studies of paclitaxel internalization from the outer to the inner wall of microtubules 121
Nucleocapsid protein: A desirable target for future therapies against HIV-1 121
Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein 119
A Class of Potent Inhibitors of the HIV-1 Nucleocapsid Protein Based on Aminopyrrolic Scaffolds 118
Use of virtual screening for discovering antiretroviral compounds interacting with the HIV-1 nucleocapsid protein. 117
Evaluation of sofosbuvir activity and resistance profile against West Nile virus in vitro. 117
Predicting the Binding Mode of Known NCp7 Inhibitors To Facilitate the Design of Novel Modulators. 115
Inhibition of melanoma cell migration and invasion targeting the hypoxic tumor associated caxii 115
null 114
Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing 114
Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (PtpB) inhibitors from natural products 113
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein 112
Functional and structural characterization of 2-amino-4-phenylthiazole inhibitors of the HIV-1 nucleocapsid protein with antiviral activity 110
Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction 107
Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog 105
(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity 100
A selective competitive inhibitor of aldehyde dehydrogenase 1A3 hinders cancer cell growth, invasiveness and stemness in vitro 100
null 100
Probing the Pore Drug Binding Site ofMicrotubules with Fluorescent Taxanes:Evidence of Two Binding Poses 98
Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines 97
Novel sulfamide-containing compounds as selective carbonic anhydrase i inhibitors 95
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma 93
Targeting GLI factors to inhibit the Hedgehog pathway 92
Histone demethylating agents as potential S-adenosyl-l-methionine-competitors 90
Nigritanine as a new potential antimicrobial alkaloid for the treatment of staphylococcus aureus-induced infections 90
Statins interfere with the attachment of S. cerevisiae mtDNA to the inner mitochondrial membrane 89
Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia 85
Experimental and Computational Druggability Exploration of the 14-3-3ζ/SOS1pS1161PPI Interface 84
A smo/gli multitarget hedgehog pathway inhibitor impairs tumor growth 83
Current trends in Hedgehog signaling pathway inhibition by small molecules 81
A Molecular Tool Targeting the Base-Flipping Activity of Human UHRF1 81
Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone 79
Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts 78
Synthetic thiosemicarbazones as a new class of Mycobacterium tuberculosis protein tyrosine phosphatase A inhibitors 76
P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation 73
Synthesis of distal and proximal fleximer base analogues and evaluation in the nucleocapsid protein of HIV-1 72
A deadly spillover: SARS-CoV-2 outbreak 72
Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge 72
Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold 71
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold 70
A chalcone derivative binds a putative allosteric site of YopH: Inhibition of a virulence factor of Yersinia 70
Excited-State Dynamics of Thienoguanosine, an Isomorphic Highly Fluorescent Analogue of Guanosine 69
One hundred faces of cyclopamine 68
Targeting the nucleocapsid protein of HIV-1 (NCp7) with nucleobase flexibility 66
A Highly Soluble Matrix Metalloproteinase-9 Inhibitor for Potential Treatment of Dry Eye Syndrome 59
Synthesis of flexible purine analog inhibitors of NCp7 58
Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia 57
Natural products as an important source in drug discovery 57
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present) 55
Molecular Dynamics Simulations and Structural Analysis of Giardia Duodenalis 14-3-3 Protein-Protein Interactions 53
Yeast as a tool to select inhibitors of the cullin deneddylating enzyme Csn5 53
INHIBITORS OF ANTIBIOTIC RESISTANCE MEDIATED BY ARN T 53
Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells 52
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype 52
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban 52
A novel colistin adjuvant identified by virtual screening for ArnT inhibitors 52
Sofosbuvir selects for drug-resistant amino acid variants in the zika virus RNA-dependent RNA-polymerase complex in vitro 51
Dual smo/braf inhibition by flavonolignans from silybum marianum† 50
Occurrence of Enantioselectivity in Nature: The Case of (S)-Norcoclaurine 50
Potency and Selectivity Optimization of Tryptophanol-Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer 49
Alvaxanthone, a thymidylate synthase inhibitor with nematocidal and tumoricidal activities 49
In Memory of Maurizio Botta: His Vision of Medicinal Chemistry 48
Inhibitory Effect of Lithospermic Acid on the HIV-1 Nucleocapsid Protein 47
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma 47
What makes thienoguanosine an outstanding fluorescent DNA probe? 44
Conformational insights into the C-terminal mutations of human rhodopsin in retinitis pigmentosa 44
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells 40
Active Components from Cassia abbreviata Prevent HIV-1 Entry by Distinct Mechanisms of Action 40
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 ddiabetes patients: Rescue by alpha-ketoglutarate and TET-TDG functional reactivation 39
Click reaction as a tool to combine pharmacophores: The case of Vismodegib 38
Repurposing drugs for the management of COVID-19 38
Ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors 37
Compounds for use in the treatment of brain diseases 36
Hydrolytic inhibition of α-chymotrypsin by 2,8,14,20-tetrakis(D-leucyl-D-valinamido)resorc[4]arenecarboxylic acid: a spectroscopic NMR and computational combined approach 36
Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment 36
Totale 9.448
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Categoria #
all - tutte 40.894
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.894
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019485 0 0 0 0 0 0 0 0 0 95 203 187
2019/20201.799 155 61 87 197 89 102 252 259 226 180 73 118
2020/20212.667 74 138 113 120 631 339 152 397 126 263 86 228
2021/20221.469 78 183 148 30 51 89 75 53 119 154 176 313
2022/20231.669 144 172 249 237 95 351 33 119 142 37 44 46
2023/20241.408 48 32 130 139 39 395 518 60 13 34 0 0
Totale 10.397