IRIS
MANGANI, STEFANO
 Distribuzione geografica
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Continente #
NA - Nord America 29.605
EU - Europa 12.445
AS - Asia 6.368
SA - Sud America 1.246
AF - Africa 121
OC - Oceania 25
Continente sconosciuto - Info sul continente non disponibili 18
Totale 49.828
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Nazione #
US - Stati Uniti d'America 29.432
GB - Regno Unito 3.066
CN - Cina 2.528
RU - Federazione Russa 2.343
IE - Irlanda 1.829
SG - Singapore 1.780
IT - Italia 1.170
SE - Svezia 1.090
BR - Brasile 1.085
UA - Ucraina 1.081
HK - Hong Kong 698
DE - Germania 611
FR - Francia 501
FI - Finlandia 393
VN - Vietnam 382
KR - Corea 351
IN - India 158
CA - Canada 101
AR - Argentina 70
TR - Turchia 64
BD - Bangladesh 58
PL - Polonia 54
IQ - Iraq 52
NL - Olanda 51
JP - Giappone 49
ES - Italia 40
AT - Austria 38
ID - Indonesia 37
ZA - Sudafrica 37
MX - Messico 36
BE - Belgio 32
CZ - Repubblica Ceca 32
SA - Arabia Saudita 26
PK - Pakistan 25
GR - Grecia 24
UZ - Uzbekistan 22
AU - Australia 21
EC - Ecuador 19
IR - Iran 18
CI - Costa d'Avorio 17
CO - Colombia 16
EU - Europa 15
EG - Egitto 14
VE - Venezuela 13
AZ - Azerbaigian 12
CL - Cile 12
KE - Kenya 12
CH - Svizzera 11
PH - Filippine 11
PY - Paraguay 11
IL - Israele 10
LT - Lituania 10
MY - Malesia 10
PT - Portogallo 10
RO - Romania 10
DO - Repubblica Dominicana 8
JM - Giamaica 8
JO - Giordania 8
KZ - Kazakistan 8
AL - Albania 7
BG - Bulgaria 7
BO - Bolivia 7
ET - Etiopia 7
TW - Taiwan 7
UY - Uruguay 7
AE - Emirati Arabi Uniti 6
EE - Estonia 6
KG - Kirghizistan 6
LB - Libano 6
NP - Nepal 6
MA - Marocco 5
PE - Perù 5
TH - Thailandia 5
DZ - Algeria 4
HR - Croazia 4
LU - Lussemburgo 4
NG - Nigeria 4
NI - Nicaragua 4
QA - Qatar 4
TN - Tunisia 4
ZM - Zambia 4
AO - Angola 3
CR - Costa Rica 3
HN - Honduras 3
KW - Kuwait 3
LV - Lettonia 3
NZ - Nuova Zelanda 3
OM - Oman 3
PA - Panama 3
SN - Senegal 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
BY - Bielorussia 2
GE - Georgia 2
LY - Libia 2
MD - Moldavia 2
MK - Macedonia 2
PS - Palestinian Territory 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
Totale 49.796
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Città #
Dallas 16.047
Southend 2.676
Dublin 1.823
Fairfield 1.724
Chandler 994
Ashburn 993
Singapore 964
Jacksonville 890
Woodbridge 814
Santa Clara 689
Wilmington 682
Seattle 657
Cambridge 625
Hong Kong 619
Moscow 612
Beijing 601
Houston 601
Ann Arbor 412
Siena 382
Seoul 349
Princeton 323
Hefei 313
Nanjing 306
Helsinki 204
Boardman 188
New York 183
Fremont 182
The Dalles 169
Los Angeles 165
San Mateo 165
Council Bluffs 126
San Diego 119
Dong Ket 103
Shanghai 102
Menlo Park 101
Ho Chi Minh City 100
Nanchang 97
Buffalo 95
São Paulo 95
Columbus 91
Munich 91
London 83
Florence 77
Redondo Beach 70
Milan 69
Bengaluru 65
Hanoi 58
Tianjin 57
Shenyang 54
Hebei 52
Kunming 50
Changsha 48
San Jose 48
Lancaster 46
San Francisco 44
Tokyo 42
Düsseldorf 41
Sesto Fiorentino 36
Zhengzhou 35
Jiaxing 34
Toronto 34
Venezia 34
Warsaw 33
Brooklyn 31
Chicago 31
Guangzhou 31
Jinan 30
Brussels 29
Dearborn 28
Ningbo 28
Norwalk 28
Poplar 27
Rio de Janeiro 27
Rome 27
Mestre 25
Montreal 25
Denver 24
Nuremberg 24
Atlanta 22
Jakarta 22
Vienna 22
Curitiba 21
Frankfurt am Main 21
Hangzhou 21
Phoenix 21
Tashkent 21
Amsterdam 20
Belo Horizonte 20
Stockholm 20
Brno 19
Trofarello 19
Baghdad 18
Boston 18
Izmir 18
Abidjan 17
Chennai 17
Pisa 17
Redwood City 17
Brasília 16
Johannesburg 16
Totale 38.420
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Nome #
1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors 7.413
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity 7.324
VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- And metallo-β-lactamases, restores activity of cefepime in enterobacterales and Pseudomonas aeruginosa 322
An update on β-lactamase inhibitor discovery and development 295
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections 263
Xanthopsin-like systems via site-specific click-functionalization of a retinoic acid binding protein 251
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease 248
X-ray absorption spectroscopy study of native and phenylphosphorodiamidate-inhibited Bacillus pasteurii urease 247
Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem 246
Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional (μ3-oxo)Tris[(μ2-peroxo)] triiron(III) cluster 245
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 244
Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs 240
Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity 237
Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam 237
Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam. 233
4-Chlorocatechol 1,2-dioxygenase from the chlorophenol-utilizing Gram-positive Rhodococcus opacus 1CP: crystallization and preliminary crystallographic analysis 231
2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives 231
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors 229
A ternary complex of carbonic anhydrase: X-ray crystallographic structure of the adduct of human carbonic anhydrase II with the activator phenylalanine and the inhibitor azide 227
A hint for the function of human Sco1 from different structures 225
A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases 225
Evidence of destabilization of the human thymidylate synthase (hTS) dimeric structure induced by the interface mutation Q62R 225
Iron binding to human heavy-chain ferritin 223
Differences in the Binding of Copper(I) to α- and β-Synuclein 221
Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction 221
Crystal and molecular structure of the ternary complex Zn(II)–ATP–2,2′-bipyridyl 220
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery 219
Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design 218
X-ray Crystal Structure of the Acinetobacter baumannii OXA-24/40 Class D Carbapenemase Inhibited by NXL104 215
An Italian contribution to structural genomics: Understanding metalloproteins 213
X-ray-diffraction Studies On Carboxypeptidase-a Complexes - the Zinc Stereochemistry 213
Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors 213
X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors 208
Crystal and molecular structure of the ternary complex bis[(adenosine 5'-triphosphato)(2,2'-bipyridine)zinc(II)] tetrahydrate 208
On nature's strategy for assigning genetic code multiplicity 207
Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H′ ferritin 204
Crystallization and preliminary crystallographic analysis of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E: a novel dioxygenase involved in the biodegradation of polychlorinated aromatic compounds 202
Crystal structure of AphA class B acid phosphatase/phosphotransferase from E. coli 201
Crystal-structure of the Complex Between Human Carbonic Anhydrase-ii and the Aromatic Inhibitor 1,2,4-triazole 201
Homodimeric Enzymes as Drug Targets 200
Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase 199
X-ray-diffraction Study of the Interaction Between Carboxypeptidase-a and (s)-(+)-1-amino-2-phenylethyl Phosphonic Acid 199
Copper(I)-alkyl sulfide and -cysteine tri-nuclear clusters as models for metallo proteins: a structural density functional analysis 199
Assisted assembly of a (µ3-oxo)-tris(µ2-peroxo)triiron(III) cluster in L-ferritins and its functional significance. 199
Discovery of ANT3310, a novel broad-spectrum serine β-Lactamase inhibitor of the diazabicyclooctane class, which strongly potentiates meropenem activity against carbapenem-resistant enterobacterales and acinetobacter baumannii 199
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS) 198
X-ray Crystallography Contributions to Drug Discovery Against Parasite 198
Crystal-structure of the Ternary Complex Between Carboxypeptidase-a, L-phenylalanine, and the Azide Ion 197
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase for the treatment of Alzheimer disease 197
Time-lapse anomalous X-ray diffraction shows how Fe(2+) substrate ions move through ferritin protein nanocages to oxidoreductase sites 196
ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-Producing enterobacteriaceae 196
A redox switch in CopC: An intriguing copper trafficking protein that binds copper(I) and copper(II) at different sites 195
A prokaryotic superoxide dismutase paralog lacking two Cu ligands: From largely unstructured in solution to ordered in the crystal 195
X-ray, Nmr and Molecular-dynamics Studies On Reduced Bovine Superoxide-dismutase - Implications For the Mechanism 195
Structure-Function Relationships of Class D Carbapenemases 194
Assembly of a Functional Triiron(III) Cluster in L-Ferritin 194
Structural characterization of a synthetic mimic of the Photoactive Yellow Protein 194
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model 193
X-ray-absorption Studies On Catechol 2,3-dioxygenase From Pseudomonas-putida Mt2 192
Structural and functional characterization of the human thymidylate synthase (hTS) interface variant R175C, new perspectives for the development of hTS inhibitors 192
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates 191
Development of flavonol and flavanone derivatives as anti-trypanosomatidic drugs 191
Identification of copper(II) binding sites in the aminoglycosidic antibiotic Neomycin B 190
Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity 189
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. Evidence for a dinuclear zinc site 189
Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases 188
XAS of dilute biological samples 188
A hint for the function of human Sco1 from different structures (vol 103, pg 8595, 2006) 188
Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart 188
High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor 184
Crystal structure and mutational analysis of FUS-1 (OXA-85), a class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum 183
Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini 183
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- And Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections 183
Anion Coordination Chemistry - Crystal-structure of the Super Complex - [h81,4,7,10,13,16,19,22,25,28-deca-azacyclotriacontane][co(cn)6]2cl2.10h 2o 182
Dynamic properties of bovine Cu,Zn superoxide dismutase from crystallographic data 181
Crystallographic determination of reduced bovine superoxide dismutase at pH 5.0 and of anion binding to its active site 181
The structure of the human glutaminyl cyclase–SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders 181
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. A new model for substrate interactions at a dinuclear cocatalytic Zn site 180
A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis casts two nickels 180
Anion Coordination Chemistry .2. Electrochemical, Thermodynamic, and Structural Studies On Supercomplex Formation Between Large Polyammonium Cycloalkanes and the 2 Complex Anions Hexacyanoferrate(ii) and Hexacyanocobaltate(iii) 178
Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction? 176
The first structure of a bacterial class B acid phosphatase reveals further structural heterogeneity among phosphatases of the haloacid dehalogenase fold 176
Carbonic-anhydrase - An Example of How the Cavity Governs the Reactivity At the Zinc Ion 175
Crystal structure of Enterococcus faecalis Thymidylate synthase 175
Structural characterization of a synthetic mimic of the Photoactive Yellow Protein 175
Structural properties of the nickel ions in urease: novel insights into the catalytic and inhibition mechanisms 173
Exafs Studies On Copper Transferrin 173
Crystal-structure of the Complex Between Carboxypeptidase-a and the Biproduct Analog Inhibitor L-benzylsuccinate At 2.0-a Resolution 173
Crystallization of soluble proteins in vapor diffusion for x-ray crystallography 172
Characterization of the zinc-binding site of the histidine-proline-rich glycoprotein associated with rabbit skeletal muscle AMP deaminase 172
Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase. 172
XAS characterization of the active sites of novel intradiol ring-cleaving dioxygenases: hydroxyquinol and chlorocatechol dioxygenases 171
Thermal-stability of Some Potassium Dibenzo-18-crown-6 Solid Compounds - Kx(db18c6) (x = Ncs, Br, I, No3) - Differential Scanning Calorimetry and X-ray-investigations 171
Interaction of Carboxypeptidase-a With Anions - Crystal-structure of the Complex With the Hpo(2-) Anion 170
Structure and properties of copper-zinc superoxide dismutases 170
A copper(I) protein possibly involved in the assembly of Cu-A center of bacterial cytochrome c oxidase 170
Structural comparison of enterococcus faecalis and human thymidylate synthase complexes with the substrate dUMP and its analogue FdUMP provides hints about enzyme conformational variabilities 170
Crystal and Molecular Structure of a Photoisomer of an Oxodipyrro-methene: The E-Isomer of 3,4-Dimethyl-2,2'-pyrromethen-5(1H)-one 168
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 167
Regiospecific Allyl-alkyne Coupling On An Organotriruthenium Carbonyl Cluster - Crystal-structure of Ru3(co)8(mu-eta-1-eta-1-eta-4-phc=c(ph)c(me)=cch2nme2) 166
Totale 34.499
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Categoria #
all - tutte 127.891
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 127.891
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.578 0 0 0 0 0 615 101 565 380 353 238 326
2021/20222.870 175 448 254 250 129 111 146 106 105 304 292 550
2022/20233.710 252 211 497 487 402 794 79 324 428 43 106 87
2023/20242.882 141 72 192 107 240 669 1.009 46 14 54 49 289
2024/20255.559 223 301 438 295 672 275 210 433 449 205 604 1.454
2025/202622.375 1.008 5.441 12.060 1.421 2.156 289 0 0 0 0 0 0
Totale 50.244