IRIS
MANGANI, STEFANO
 Distribuzione geografica
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Continente #
NA - Nord America 11.704
EU - Europa 10.289
AS - Asia 1.996
SA - Sud America 83
AF - Africa 34
OC - Oceania 24
Continente sconosciuto - Info sul continente non disponibili 17
Totale 24.147
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Nazione #
US - Stati Uniti d'America 11.648
GB - Regno Unito 2.952
IE - Irlanda 1.831
CN - Cina 1.295
SE - Svezia 1.069
UA - Ucraina 1.068
IT - Italia 1.045
RU - Federazione Russa 758
DE - Germania 517
FR - Francia 468
FI - Finlandia 369
SG - Singapore 369
VN - Vietnam 108
HK - Hong Kong 80
BR - Brasile 67
CA - Canada 50
CZ - Repubblica Ceca 31
NL - Olanda 30
TR - Turchia 29
BE - Belgio 28
IN - India 26
AU - Australia 21
GR - Grecia 19
PL - Polonia 19
ES - Italia 17
CI - Costa d'Avorio 16
EU - Europa 15
AT - Austria 14
CH - Svizzera 11
IR - Iran 11
JP - Giappone 9
RO - Romania 9
IL - Israele 8
EG - Egitto 7
IQ - Iraq 7
UZ - Uzbekistan 6
PT - Portogallo 5
SA - Arabia Saudita 5
TW - Taiwan 5
KG - Kirghizistan 4
KZ - Kazakistan 4
LU - Lussemburgo 4
BD - Bangladesh 3
BG - Bulgaria 3
CO - Colombia 3
EC - Ecuador 3
EE - Estonia 3
LT - Lituania 3
MY - Malesia 3
NZ - Nuova Zelanda 3
PH - Filippine 3
PK - Pakistan 3
TH - Thailandia 3
ZM - Zambia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AE - Emirati Arabi Uniti 2
AL - Albania 2
AR - Argentina 2
AZ - Azerbaigian 2
BO - Bolivia 2
CL - Cile 2
HR - Croazia 2
ID - Indonesia 2
KR - Corea 2
LV - Lettonia 2
MK - Macedonia 2
NG - Nigeria 2
PA - Panama 2
QA - Qatar 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
CG - Congo 1
CY - Cipro 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
GY - Guiana 1
HU - Ungheria 1
IM - Isola di Man 1
JM - Giamaica 1
KE - Kenya 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
MD - Moldavia 1
MX - Messico 1
NO - Norvegia 1
PE - Perù 1
PS - Palestinian Territory 1
RS - Serbia 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
SV - El Salvador 1
TN - Tunisia 1
UY - Uruguay 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 24.147
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Città #
Southend 2.676
Dublin 1.826
Fairfield 1.723
Chandler 994
Jacksonville 887
Woodbridge 813
Ashburn 798
Wilmington 682
Santa Clara 655
Seattle 651
Cambridge 625
Houston 594
Ann Arbor 412
Siena 382
Princeton 323
Nanjing 305
Singapore 222
Beijing 221
Helsinki 202
Boardman 183
Fremont 182
San Mateo 165
New York 129
San Diego 116
Moscow 108
Dong Ket 103
Menlo Park 101
Nanchang 97
Shanghai 87
London 69
Florence 59
Hebei 52
Shenyang 52
Tianjin 52
Kunming 49
Changsha 46
Lancaster 46
Milan 36
Sesto Fiorentino 36
Jiaxing 34
Venezia 34
Düsseldorf 33
Munich 32
Jinan 30
Zhengzhou 30
Toronto 29
Brussels 28
Dearborn 28
Ningbo 28
Norwalk 28
Mestre 25
San Francisco 25
Rome 23
Brno 19
Guangzhou 19
Trofarello 19
Frankfurt am Main 17
Hangzhou 17
Pisa 17
Redwood City 17
Abidjan 16
Amsterdam 16
Izmir 16
Tappahannock 16
Los Angeles 15
Chicago 13
Prato 12
Taizhou 12
Vienna 12
Hounslow 11
Olomouc 11
Phoenix 11
Bologna 10
Prescot 10
São Paulo 10
Canberra 9
Gdynia 9
Kilburn 9
Lanzhou 9
Redmond 8
West Jordan 8
Auburn Hills 7
Berlin 7
Changchun 7
Columbus 7
Fuzhou 7
Hefei 7
Zurich 7
Bari 6
Cairo 6
Chengdu 6
Falls Church 6
Madrid 6
Nuremberg 6
Paris 6
Sydney 6
Zanjan 6
Chiswick 5
Indiana 5
Martellago 5
Totale 17.652
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Nome #
VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- And metallo-β-lactamases, restores activity of cefepime in enterobacterales and Pseudomonas aeruginosa 243
Xanthopsin-like systems via site-specific click-functionalization of a retinoic acid binding protein 209
An update on β-lactamase inhibitor discovery and development 205
X-ray absorption spectroscopy study of native and phenylphosphorodiamidate-inhibited Bacillus pasteurii urease 187
Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs 185
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections 181
Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem 179
Differences in the Binding of Copper(I) to α- and β-Synuclein 173
Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional (μ3-oxo)Tris[(μ2-peroxo)] triiron(III) cluster 170
X-ray-diffraction Studies On Carboxypeptidase-a Complexes - the Zinc Stereochemistry 168
Crystal-structure of the Complex Between Human Carbonic Anhydrase-ii and the Aromatic Inhibitor 1,2,4-triazole 166
X-ray, Nmr and Molecular-dynamics Studies On Reduced Bovine Superoxide-dismutase - Implications For the Mechanism 165
Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity 163
Iron binding to human heavy-chain ferritin 163
On nature's strategy for assigning genetic code multiplicity 162
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model 162
Homodimeric Enzymes as Drug Targets 158
Structure-Function Relationships of Class D Carbapenemases 158
Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase 157
Time-lapse anomalous X-ray diffraction shows how Fe(2+) substrate ions move through ferritin protein nanocages to oxidoreductase sites 157
X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors 156
Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors 156
Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart 155
X-ray Crystallography Contributions to Drug Discovery Against Parasite 154
Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H′ ferritin 153
X-ray-diffraction Study of the Interaction Between Carboxypeptidase-a and (s)-(+)-1-amino-2-phenylethyl Phosphonic Acid 152
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery 152
X-ray Crystal Structure of the Acinetobacter baumannii OXA-24/40 Class D Carbapenemase Inhibited by NXL104 151
2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives 150
XAS of dilute biological samples 147
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease 147
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS) 145
A ternary complex of carbonic anhydrase: X-ray crystallographic structure of the adduct of human carbonic anhydrase II with the activator phenylalanine and the inhibitor azide 144
Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam 144
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 144
Copper(I)-alkyl sulfide and -cysteine tri-nuclear clusters as models for metallo proteins: a structural density functional analysis 143
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- And Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections 142
X-ray-absorption Studies On Catechol 2,3-dioxygenase From Pseudomonas-putida Mt2 140
Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam. 140
The first structure of a bacterial class B acid phosphatase reveals further structural heterogeneity among phosphatases of the haloacid dehalogenase fold 140
Crystal structure of AphA class B acid phosphatase/phosphotransferase from E. coli 139
Crystal-structure of the Ternary Complex Between Carboxypeptidase-a, L-phenylalanine, and the Azide Ion 138
A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases 138
Crystal and molecular structure of the ternary complex bis[(adenosine 5'-triphosphato)(2,2'-bipyridine)zinc(II)] tetrahydrate 138
Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity 137
The structure of the human glutaminyl cyclase–SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders 137
Structural and functional characterization of the human thymidylate synthase (hTS) interface variant R175C, new perspectives for the development of hTS inhibitors 137
Evidence of destabilization of the human thymidylate synthase (hTS) dimeric structure induced by the interface mutation Q62R 137
Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction? 136
Crystallographic determination of reduced bovine superoxide dismutase at pH 5.0 and of anion binding to its active site 136
Interaction of Carboxypeptidase-a With Anions - Crystal-structure of the Complex With the Hpo(2-) Anion 135
Protein–Protein Interactions in the Solid State: The Troubles of Crystallizing Protein–Protein Complexes 135
Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase. 135
Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design 134
Assembly of a Functional Triiron(III) Cluster in L-Ferritin 134
Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini 134
Exafs Studies On Copper Transferrin 133
Carbonic-anhydrase - An Example of How the Cavity Governs the Reactivity At the Zinc Ion 133
1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors 132
X-ray studies of the binding of small anionic inhibitors at the carboxypeptidase A active site 132
Crystal and molecular structure of the ternary complex Zn(II)–ATP–2,2′-bipyridyl 132
Structure and properties of copper-zinc superoxide dismutases 131
Thermal-stability of Some Potassium Dibenzo-18-crown-6 Solid Compounds - Kx(db18c6) (x = Ncs, Br, I, No3) - Differential Scanning Calorimetry and X-ray-investigations 131
Crystallization and preliminary crystallographic analysis of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E: a novel dioxygenase involved in the biodegradation of polychlorinated aromatic compounds 131
4-Chlorocatechol 1,2-dioxygenase from the chlorophenol-utilizing Gram-positive Rhodococcus opacus 1CP: crystallization and preliminary crystallographic analysis 130
Crystallization of soluble proteins in vapor diffusion for x-ray crystallography 129
Crystal-structure of the Complex Between Carboxypeptidase-a and the Biproduct Analog Inhibitor L-benzylsuccinate At 2.0-a Resolution 129
Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction 128
A hint for the function of human Sco1 from different structures 127
Identification of copper(II) binding sites in the aminoglycosidic antibiotic Neomycin B 127
Regiospecific Allyl-alkyne Coupling On An Organotriruthenium Carbonyl Cluster - Crystal-structure of Ru3(co)8(mu-eta-1-eta-1-eta-4-phc=c(ph)c(me)=cch2nme2) 127
Polynuclear Zinc(ii) Complexes With Large Polyazacycloalkanes - Equilibrium Studies and Crystal-structure of the Binuclear [zn2([30]anen10)(ncs)](clo4)3 Complex 127
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity 126
Structural properties of the nickel ions in urease: novel insights into the catalytic and inhibition mechanisms 126
XAS characterization of the active sites of novel intradiol ring-cleaving dioxygenases: hydroxyquinol and chlorocatechol dioxygenases 125
Disruption of Protein-Protein Interfaces 125
Crystal and Molecular Structure of a Photoisomer of an Oxodipyrro-methene: The E-Isomer of 3,4-Dimethyl-2,2'-pyrromethen-5(1H)-one 124
An Italian contribution to structural genomics: Understanding metalloproteins 124
The crystal structure of the monomeric human SOD mutant F50E/G51E/E133Q at atomic resolution. The enzyme mechanism revisited 124
A redox switch in CopC: An intriguing copper trafficking protein that binds copper(I) and copper(II) at different sites 124
Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine 124
Dynamic properties of bovine Cu,Zn superoxide dismutase from crystallographic data 122
The Dependence of Cis-diamminedichloroplatinum(ii) Binding To Dna Upon the Gc Content - A Thermal and Spectrophotometric Investigation 122
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. A new model for substrate interactions at a dinuclear cocatalytic Zn site 121
Fragmenting the S100B-p53 Interaction: Combined Virtual/Biophysical Screening Approaches to Identify Ligands 121
Characterization of the zinc-binding site of the histidine-proline-rich glycoprotein associated with rabbit skeletal muscle AMP deaminase 121
Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC  beta-Lactamases 120
null 120
Exafs Studies On the Oxalate Adduct of Iron Transferrin 119
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates 119
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. Evidence for a dinuclear zinc site 119
The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction 118
The soluble Y115E-Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease 118
A prokaryotic superoxide dismutase paralog lacking two Cu ligands: From largely unstructured in solution to ordered in the crystal 118
Structural Insights into the Ferroxidase Site of Ferritins from Higher Eukaryotes 117
Structural characterization of a synthetic mimic of the Photoactive Yellow Protein 117
From an inactive prokaryotic SOD homologue to an active protein through site-directed mutagenesis 116
Structural comparison of enterococcus faecalis and human thymidylate synthase complexes with the substrate dUMP and its analogue FdUMP provides hints about enzyme conformational variabilities 116
Molecular details of urease inhibition by boric acid: insights into the catalytic mechanism 115
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 115
Totale 14.101
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Categoria #
all - tutte 82.677
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 82.677
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.176 0 0 0 0 0 0 375 603 381 409 107 301
2020/20213.826 107 430 87 360 264 615 101 565 380 353 238 326
2021/20222.870 175 448 254 250 129 111 146 106 105 304 292 550
2022/20233.716 252 211 497 487 404 794 79 325 430 43 107 87
2023/20242.895 141 73 193 109 241 673 1.012 46 15 54 49 289
2024/20252.216 224 301 440 295 676 277 3 0 0 0 0 0
Totale 24.545