IRIS
MANGANI, STEFANO
 Distribuzione geografica
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Continente #
NA - Nord America 30.501
EU - Europa 12.895
AS - Asia 7.548
SA - Sud America 1.394
AF - Africa 269
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 18
Totale 52.651
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Nazione #
US - Stati Uniti d'America 30.296
GB - Regno Unito 3.128
CN - Cina 2.726
RU - Federazione Russa 2.346
SG - Singapore 2.205
IE - Irlanda 1.832
IT - Italia 1.218
BR - Brasile 1.166
SE - Svezia 1.094
UA - Ucraina 1.085
HK - Hong Kong 749
FR - Francia 722
VN - Vietnam 677
DE - Germania 640
FI - Finlandia 414
KR - Corea 351
IN - India 210
ZA - Sudafrica 116
CA - Canada 110
AR - Argentina 89
IQ - Iraq 82
BD - Bangladesh 78
TR - Turchia 73
NL - Olanda 69
JP - Giappone 59
PL - Polonia 59
ES - Italia 52
ID - Indonesia 49
MX - Messico 47
PK - Pakistan 40
AT - Austria 39
BE - Belgio 33
NG - Nigeria 33
CZ - Repubblica Ceca 32
SA - Arabia Saudita 32
EC - Ecuador 29
VE - Venezuela 28
GR - Grecia 26
UZ - Uzbekistan 26
CL - Cile 23
KE - Kenya 22
AU - Australia 21
PH - Filippine 21
CI - Costa d'Avorio 20
CO - Colombia 20
EG - Egitto 18
IR - Iran 18
CH - Svizzera 16
MY - Malesia 16
EU - Europa 15
JO - Giordania 15
AZ - Azerbaigian 14
IL - Israele 14
MA - Marocco 12
NP - Nepal 12
PY - Paraguay 12
RO - Romania 12
JM - Giamaica 11
LT - Lituania 11
TN - Tunisia 11
UY - Uruguay 11
KZ - Kazakistan 10
PT - Portogallo 10
AE - Emirati Arabi Uniti 9
AL - Albania 9
BG - Bulgaria 9
DZ - Algeria 9
ET - Etiopia 9
LB - Libano 9
DO - Repubblica Dominicana 8
PE - Perù 8
TW - Taiwan 8
BO - Bolivia 7
EE - Estonia 6
KG - Kirghizistan 6
PA - Panama 6
NI - Nicaragua 5
OM - Oman 5
PS - Palestinian Territory 5
TH - Thailandia 5
CR - Costa Rica 4
HR - Croazia 4
LU - Lussemburgo 4
NZ - Nuova Zelanda 4
QA - Qatar 4
RS - Serbia 4
TT - Trinidad e Tobago 4
ZM - Zambia 4
AO - Angola 3
BY - Bielorussia 3
HN - Honduras 3
KW - Kuwait 3
LV - Lettonia 3
LY - Libia 3
SN - Senegal 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
BA - Bosnia-Erzegovina 2
GE - Georgia 2
GT - Guatemala 2
Totale 52.611
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Città #
Dallas 16.051
Southend 2.676
Dublin 1.826
Fairfield 1.724
Singapore 1.297
Ashburn 1.038
Chandler 994
Jacksonville 891
Woodbridge 815
Santa Clara 700
Wilmington 682
Seattle 657
Hong Kong 652
Cambridge 625
Moscow 612
Beijing 610
Houston 602
San Jose 431
Ann Arbor 412
Siena 382
Hefei 373
Seoul 349
Princeton 323
Nanjing 306
The Dalles 277
Council Bluffs 249
Helsinki 223
Lauterbourg 200
Los Angeles 193
Boardman 189
New York 189
Fremont 182
Ho Chi Minh City 180
San Mateo 165
Hanoi 148
San Diego 121
Shanghai 104
Dong Ket 103
Menlo Park 101
São Paulo 100
Nanchang 97
Buffalo 96
Johannesburg 93
Columbus 91
Munich 91
London 88
Florence 80
Milan 75
Redondo Beach 70
Bengaluru 67
Orem 59
Tianjin 58
Shenyang 54
Hebei 52
Tokyo 51
Kunming 50
Changsha 48
Lancaster 47
San Francisco 46
Frankfurt am Main 42
Düsseldorf 41
Toronto 37
Sesto Fiorentino 36
Chicago 35
Warsaw 35
Zhengzhou 35
Jiaxing 34
Venezia 34
Guangzhou 33
Brooklyn 32
Amsterdam 31
Kensington 31
Rome 31
Jinan 30
Rio de Janeiro 30
Brussels 29
Chennai 29
Baghdad 28
Dearborn 28
Denver 28
Ningbo 28
Norwalk 28
Abuja 27
Nuremberg 27
Poplar 27
Atlanta 26
Montreal 26
Mestre 25
Tashkent 25
Curitiba 24
Belo Horizonte 23
Hangzhou 23
Jakarta 23
Da Nang 22
Stockholm 22
Vienna 22
Manchester 21
Phoenix 21
Abidjan 20
Dhaka 20
Totale 40.234
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Nome #
1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors 7.460
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity 7.350
VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- And metallo-β-lactamases, restores activity of cefepime in enterobacterales and Pseudomonas aeruginosa 339
An update on β-lactamase inhibitor discovery and development 322
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease 279
Xanthopsin-like systems via site-specific click-functionalization of a retinoic acid binding protein 274
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections 273
Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional (μ3-oxo)Tris[(μ2-peroxo)] triiron(III) cluster 268
X-ray absorption spectroscopy study of native and phenylphosphorodiamidate-inhibited Bacillus pasteurii urease 264
Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem 264
Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs 263
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 263
Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity 261
Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam 257
Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction 250
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors 250
Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam. 249
Iron binding to human heavy-chain ferritin 247
4-Chlorocatechol 1,2-dioxygenase from the chlorophenol-utilizing Gram-positive Rhodococcus opacus 1CP: crystallization and preliminary crystallographic analysis 245
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery 245
2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives 243
A hint for the function of human Sco1 from different structures 241
A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases 241
Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design 240
A ternary complex of carbonic anhydrase: X-ray crystallographic structure of the adduct of human carbonic anhydrase II with the activator phenylalanine and the inhibitor azide 236
Evidence of destabilization of the human thymidylate synthase (hTS) dimeric structure induced by the interface mutation Q62R 236
Crystal and molecular structure of the ternary complex Zn(II)–ATP–2,2′-bipyridyl 234
Differences in the Binding of Copper(I) to α- and β-Synuclein 233
An Italian contribution to structural genomics: Understanding metalloproteins 231
Crystal and molecular structure of the ternary complex bis[(adenosine 5'-triphosphato)(2,2'-bipyridine)zinc(II)] tetrahydrate 231
X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors 227
Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors 225
X-ray Crystal Structure of the Acinetobacter baumannii OXA-24/40 Class D Carbapenemase Inhibited by NXL104 223
X-ray-diffraction Studies On Carboxypeptidase-a Complexes - the Zinc Stereochemistry 220
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase for the treatment of Alzheimer disease 219
Crystal structure of AphA class B acid phosphatase/phosphotransferase from E. coli 218
Time-lapse anomalous X-ray diffraction shows how Fe(2+) substrate ions move through ferritin protein nanocages to oxidoreductase sites 218
Discovery of ANT3310, a novel broad-spectrum serine β-Lactamase inhibitor of the diazabicyclooctane class, which strongly potentiates meropenem activity against carbapenem-resistant enterobacterales and acinetobacter baumannii 218
On nature's strategy for assigning genetic code multiplicity 217
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model 215
Copper(I)-alkyl sulfide and -cysteine tri-nuclear clusters as models for metallo proteins: a structural density functional analysis 214
Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H′ ferritin 214
Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase 213
Homodimeric Enzymes as Drug Targets 213
Assisted assembly of a (µ3-oxo)-tris(µ2-peroxo)triiron(III) cluster in L-ferritins and its functional significance. 213
Development of flavonol and flavanone derivatives as anti-trypanosomatidic drugs 213
ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-Producing enterobacteriaceae 213
Crystallization and preliminary crystallographic analysis of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E: a novel dioxygenase involved in the biodegradation of polychlorinated aromatic compounds 212
Crystal-structure of the Complex Between Human Carbonic Anhydrase-ii and the Aromatic Inhibitor 1,2,4-triazole 211
A prokaryotic superoxide dismutase paralog lacking two Cu ligands: From largely unstructured in solution to ordered in the crystal 211
Identification of copper(II) binding sites in the aminoglycosidic antibiotic Neomycin B 210
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS) 210
A redox switch in CopC: An intriguing copper trafficking protein that binds copper(I) and copper(II) at different sites 209
X-ray, Nmr and Molecular-dynamics Studies On Reduced Bovine Superoxide-dismutase - Implications For the Mechanism 208
Assembly of a Functional Triiron(III) Cluster in L-Ferritin 208
X-ray Crystallography Contributions to Drug Discovery Against Parasite 208
X-ray-diffraction Study of the Interaction Between Carboxypeptidase-a and (s)-(+)-1-amino-2-phenylethyl Phosphonic Acid 207
Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases 206
Crystal-structure of the Ternary Complex Between Carboxypeptidase-a, L-phenylalanine, and the Azide Ion 205
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates 205
Structural and functional characterization of the human thymidylate synthase (hTS) interface variant R175C, new perspectives for the development of hTS inhibitors 205
Structural characterization of a synthetic mimic of the Photoactive Yellow Protein 205
Structure-Function Relationships of Class D Carbapenemases 204
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- And Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections 204
A hint for the function of human Sco1 from different structures (vol 103, pg 8595, 2006) 201
X-ray-absorption Studies On Catechol 2,3-dioxygenase From Pseudomonas-putida Mt2 201
XAS of dilute biological samples 200
Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart 200
Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity 199
Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini 198
High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor 198
The structure of the human glutaminyl cyclase–SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders 197
A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis casts two nickels 196
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. Evidence for a dinuclear zinc site 195
Anion Coordination Chemistry .2. Electrochemical, Thermodynamic, and Structural Studies On Supercomplex Formation Between Large Polyammonium Cycloalkanes and the 2 Complex Anions Hexacyanoferrate(ii) and Hexacyanocobaltate(iii) 195
Dynamic properties of bovine Cu,Zn superoxide dismutase from crystallographic data 193
Crystallographic determination of reduced bovine superoxide dismutase at pH 5.0 and of anion binding to its active site 193
Structural characterization of a synthetic mimic of the Photoactive Yellow Protein 192
Anion Coordination Chemistry - Crystal-structure of the Super Complex - [h81,4,7,10,13,16,19,22,25,28-deca-azacyclotriacontane][co(cn)6]2cl2.10h 2o 191
Crystal structure and mutational analysis of FUS-1 (OXA-85), a class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum 191
Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction? 190
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. A new model for substrate interactions at a dinuclear cocatalytic Zn site 188
Crystal-structure of the Complex Between Carboxypeptidase-a and the Biproduct Analog Inhibitor L-benzylsuccinate At 2.0-a Resolution 188
Structural properties of the nickel ions in urease: novel insights into the catalytic and inhibition mechanisms 186
Characterization of the zinc-binding site of the histidine-proline-rich glycoprotein associated with rabbit skeletal muscle AMP deaminase 183
Crystallization of soluble proteins in vapor diffusion for x-ray crystallography 182
Thermal-stability of Some Potassium Dibenzo-18-crown-6 Solid Compounds - Kx(db18c6) (x = Ncs, Br, I, No3) - Differential Scanning Calorimetry and X-ray-investigations 182
The first structure of a bacterial class B acid phosphatase reveals further structural heterogeneity among phosphatases of the haloacid dehalogenase fold 182
XAS characterization of the active sites of novel intradiol ring-cleaving dioxygenases: hydroxyquinol and chlorocatechol dioxygenases 181
Interaction of Carboxypeptidase-a With Anions - Crystal-structure of the Complex With the Hpo(2-) Anion 181
Crystal structure of Enterococcus faecalis Thymidylate synthase 181
Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase. 181
A copper(I) protein possibly involved in the assembly of Cu-A center of bacterial cytochrome c oxidase 181
Carbonic-anhydrase - An Example of How the Cavity Governs the Reactivity At the Zinc Ion 180
Structural comparison of enterococcus faecalis and human thymidylate synthase complexes with the substrate dUMP and its analogue FdUMP provides hints about enzyme conformational variabilities 180
Crystal and Molecular Structure of a Photoisomer of an Oxodipyrro-methene: The E-Isomer of 3,4-Dimethyl-2,2'-pyrromethen-5(1H)-one 179
Exafs Studies On Copper Transferrin 178
Structure and properties of copper-zinc superoxide dismutases 178
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 177
Regiospecific Allyl-alkyne Coupling On An Organotriruthenium Carbonyl Cluster - Crystal-structure of Ru3(co)8(mu-eta-1-eta-1-eta-4-phc=c(ph)c(me)=cch2nme2) 175
Totale 35.983
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Categoria #
all - tutte 133.220
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 133.220
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021917 0 0 0 0 0 0 0 0 0 353 238 326
2021/20222.870 175 448 254 250 129 111 146 106 105 304 292 550
2022/20233.710 252 211 497 487 402 794 79 324 428 43 106 87
2023/20242.882 141 72 192 107 240 669 1.009 46 14 54 49 289
2024/20255.559 223 301 438 295 672 275 210 433 449 205 604 1.454
2025/202625.198 1.008 5.441 12.060 1.421 2.156 505 1.183 336 539 549 0 0
Totale 53.067