PATRUSSI, LAURA
 Distribuzione geografica
Continente #
NA - Nord America 3.494
EU - Europa 3.088
AS - Asia 365
Continente sconosciuto - Info sul continente non disponibili 3
SA - Sud America 3
AF - Africa 2
OC - Oceania 2
Totale 6.957
Nazione #
US - Stati Uniti d'America 3.484
GB - Regno Unito 980
IT - Italia 582
IE - Irlanda 563
SE - Svezia 313
CN - Cina 265
UA - Ucraina 202
FR - Francia 153
DE - Germania 113
FI - Finlandia 87
VN - Vietnam 43
ES - Italia 31
BE - Belgio 29
JP - Giappone 12
TR - Turchia 11
CA - Canada 8
CH - Svizzera 8
IN - India 7
IR - Iran 7
NL - Olanda 7
GR - Grecia 4
SG - Singapore 4
CZ - Repubblica Ceca 3
EU - Europa 3
IQ - Iraq 3
AT - Austria 2
AU - Australia 2
BR - Brasile 2
LU - Lussemburgo 2
PA - Panama 2
PT - Portogallo 2
TW - Taiwan 2
AR - Argentina 1
BG - Bulgaria 1
EE - Estonia 1
EG - Egitto 1
HK - Hong Kong 1
HU - Ungheria 1
ID - Indonesia 1
IL - Israele 1
JO - Giordania 1
KG - Kirghizistan 1
LK - Sri Lanka 1
MA - Marocco 1
MD - Moldavia 1
MY - Malesia 1
PK - Pakistan 1
RO - Romania 1
RU - Federazione Russa 1
SA - Arabia Saudita 1
SI - Slovenia 1
TH - Thailandia 1
UZ - Uzbekistan 1
Totale 6.957
Città #
Southend 908
Dublin 555
Ashburn 547
Fairfield 440
Menlo Park 360
Chandler 305
Siena 208
Woodbridge 204
Seattle 176
Ann Arbor 172
Wilmington 171
Jacksonville 169
Houston 148
Cambridge 135
Princeton 93
Florence 64
Nanjing 61
Helsinki 57
Beijing 47
Dong Ket 43
New York 38
Dearborn 35
Shanghai 32
San Diego 28
Boardman 27
Brussels 27
Málaga 26
San Mateo 24
Shenyang 20
Fremont 17
Rome 17
Nanchang 16
Redwood City 14
Lancaster 13
Milan 13
London 11
Kunming 10
Nagareyama 10
Norwalk 10
Venezia 10
Greve in Chianti 9
Hefei 9
Prato 9
Hebei 8
Jiaxing 8
Phoenix 7
Bacoli 6
Izmir 6
Jinan 6
Mestre 6
Ningbo 6
San Francisco 6
Schoenebeck 6
Tianjin 6
Lausanne 5
Los Angeles 5
Merate 5
Scarperia 5
Washington 5
Düsseldorf 4
Hangzhou 4
Inverigo 4
Kilburn 4
Marano di Napoli 4
Padova 4
Perugia 4
Toronto 4
Amsterdam 3
Anguillara Sabazia 3
Azzate 3
Cantagallo 3
Guangzhou 3
Hounslow 3
Lanzhou 3
Madrid 3
Monastier di Treviso 3
Monmouth Junction 3
New Bedfont 3
Paullo 3
Pescara 3
Pune 3
Scandicci 3
Taizhou 3
Tappahannock 3
Toulouse 3
Afragola 2
Arezzo 2
Auburn Hills 2
Bergamo 2
Brescia 2
Brindisi 2
Brno 2
Busto Arsizio 2
Cagliari 2
Cecina 2
Changsha 2
Chiswick 2
Conselve 2
Duffel 2
Falkenstein 2
Totale 5.500
Nome #
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T cell antigen receptor signaling to Ras family GTPases and Myc dependent survival 453
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape 252
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system 220
The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis 212
Analysis of TCR/CD3 recycling at the immune synapse 204
Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment 204
The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse 197
Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia 196
Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells 189
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia 177
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes 176
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 168
Lack of p66Shc in the CLL mouse model E mu-TCL1 exacerbates nodal and extranodal infiltration of leukemic cells which can undergo Richter's transformation 159
The Rab GTPase Rab8 as a shared regulator of ciliogenesis and immune synapse assembly: from a conserved pathway to diverse cellular structures 159
The CXCL12/CXCR4 Axis as a Therapeutic Target in Cancer and HIV-1 Infection. 157
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T-cells 155
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis. 148
Nonsteroidal anti-inflammatory drugs inhibit a Fyn dependent pathway coupled to Rac and stress kinase activation in TCR signaling 148
The B-side of the immune response 148
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy 147
Simvastatin inhibits T cell activation by selectively impairing the function of RAS superfamily GTPases 144
Boosting chemokine receptor recycling: An elixir of life for chronic lymphocytic leukemia 144
Themis releases the brakes on TCR signaling during thymocyte selection by disabling SHP-1 141
Intracellular mediators of CXCR4-dependent signaling in T-cells 139
The Glycerophosphoinositols: From Lipid Metabolites to Modulators of T-Cell Signaling 138
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays 138
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 135
Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases. 129
F-actin dynamics controls segregation of the TCR signaling cascade to clustered lipid rafts 128
Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc. 126
p66Shc-dependent apoptosis requires Lck and CaMKII activity 125
Dysfunctional immune synapses in T cell immunodeficiencies 119
Defective Vav expression and impaired F-actin reorganization in a subset of common variable immunodeficiency patients with T-cell defects 113
Mucosal B cells 111
Astrocyte deficiency of the Shc family member Rai attenuates myelin-reactive Th17 cell-dependent neurodegeneration in EAE: a mechanistic study of astrocyte-T cell interactions 109
Anthrax toxins inhibit immune cell chemotaxis 107
The adenylate cyclase toxin of Bordetella pertussis binds to T cells via the integrin LFA-1 and induces its disengagement from the immune synapse 105
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling. 105
p66Shc promotes apoptosis and antagonises mitogenic signaling in T cells. 98
Glycerophosphoinositol-4-phosphate enhances SDF-1?-stimulated T-cell chemotaxis through PTK-dependent activation of Vav 98
The Helicobacter pylori vacuolating toxin inhibits T-cell activation by two independent mechanisms 83
p66Shc promotes apoptosis and antagonises mitogenic signaling in T-cells 71
Fetal Myocardial Expression of GLUT1: Roles of BPA Exposure and Cord Blood Exosomes in a Rat Model 70
P66shc: A pleiotropic regulator of B cell trafficking and a gatekeeper in chronic lymphocytic leukemia 64
Anthrax toxins suppress immune cell activation and chemotaxis by perturbing receptor signaling 63
Regulation of lymphocyte trafficking by p66Shc: novel insight into CLL B cell survival 56
Reduced p66Shc expression in Chronic lymphocytic leukemia (CLL) B cells enhances CXCR4/CCR7 recycling and impairs S1P1 expression promoting their lymph node accumulation 55
Nature vs. Nurture: The Two Opposing Behaviors of Cytotoxic T Lymphocytes in the Tumor Microenvironment 55
p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB 53
P66Shc deficiency promotes B cell chemotaxis by enhancing CXCR4 and CCR7 recycling in Chronic Lymphocytic Leukemia 42
Negative regulation of chemokine receptor signalling and B cell chemotaxis by p66Shc 41
Learning from TCR Signaling and Immunological Synapse Assembly to Build New Chimeric Antigen Receptors (CARs). 41
Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation 39
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia 26
Interleukin (IL)-9 Supports the Tumor-Promoting Environment of Chronic Lymphocytic Leukemia 25
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 15
p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation 12
Totale 7.132
Categoria #
all - tutte 21.401
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.401


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019166 0 0 0 0 0 0 0 0 0 0 0 166
2019/20201.248 157 43 71 189 109 111 103 151 113 100 33 68
2020/20211.091 59 73 29 76 98 111 51 159 105 143 108 79
2021/2022871 52 92 30 98 72 26 45 38 48 97 100 173
2022/20231.175 88 142 150 155 113 207 23 88 112 39 38 20
2023/20241.257 35 18 106 52 50 248 320 322 4 34 33 35
Totale 7.132