IRIS
PATRUSSI, LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 3.539
EU - Europa 3.474
AS - Asia 490
AF - Africa 20
Continente sconosciuto - Info sul continente non disponibili 3
SA - Sud America 3
OC - Oceania 2
Totale 7.531
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Nazione #
US - Stati Uniti d'America 3.525
GB - Regno Unito 985
IT - Italia 694
IE - Irlanda 563
SE - Svezia 314
CN - Cina 277
RU - Federazione Russa 221
UA - Ucraina 204
FR - Francia 154
DE - Germania 130
SG - Singapore 106
FI - Finlandia 92
VN - Vietnam 44
ES - Italia 32
BE - Belgio 29
CI - Costa d'Avorio 17
JP - Giappone 13
NL - Olanda 13
CA - Canada 11
TR - Turchia 11
CZ - Repubblica Ceca 10
IR - Iran 9
CH - Svizzera 8
IN - India 7
GR - Grecia 4
AT - Austria 3
EU - Europa 3
HK - Hong Kong 3
IL - Israele 3
IQ - Iraq 3
PT - Portogallo 3
TW - Taiwan 3
AU - Australia 2
BR - Brasile 2
EG - Egitto 2
HU - Ungheria 2
LK - Sri Lanka 2
LU - Lussemburgo 2
PA - Panama 2
PL - Polonia 2
AL - Albania 1
AR - Argentina 1
BG - Bulgaria 1
CR - Costa Rica 1
EE - Estonia 1
ID - Indonesia 1
JO - Giordania 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LT - Lituania 1
MA - Marocco 1
MD - Moldavia 1
MY - Malesia 1
PK - Pakistan 1
RO - Romania 1
RS - Serbia 1
SA - Arabia Saudita 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
UZ - Uzbekistan 1
Totale 7.531
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Città #
Southend 908
Dublin 555
Ashburn 550
Fairfield 440
Menlo Park 360
Chandler 305
Siena 234
Woodbridge 204
Seattle 176
Ann Arbor 172
Wilmington 171
Jacksonville 169
Houston 148
Cambridge 135
Princeton 93
Florence 81
Singapore 79
Nanjing 61
Helsinki 60
Beijing 47
Dong Ket 43
New York 38
Dearborn 35
Shanghai 35
Moscow 28
San Diego 28
Boardman 27
Brussels 27
Málaga 26
San Mateo 24
Rome 22
Shenyang 20
Milan 19
Abidjan 17
Fremont 17
Nanchang 16
Munich 15
Redwood City 14
Lancaster 13
London 11
Kunming 10
Nagareyama 10
Norwalk 10
Venezia 10
Brno 9
Columbus 9
Greve in Chianti 9
Hefei 9
Prato 9
Hebei 8
Jiaxing 8
Mestre 7
Padova 7
Phoenix 7
Bacoli 6
Dallas 6
Izmir 6
Jinan 6
Los Angeles 6
Ningbo 6
San Francisco 6
Santa Clara 6
Schoenebeck 6
Tianjin 6
Lausanne 5
Merate 5
Scarperia 5
Toronto 5
Washington 5
Amsterdam 4
Düsseldorf 4
Hangzhou 4
Inverigo 4
Kilburn 4
Marano di Napoli 4
Perugia 4
Anguillara Sabazia 3
Azzate 3
Cantagallo 3
Guangzhou 3
Hounslow 3
Lanzhou 3
Lappeenranta 3
Livorno 3
Madrid 3
Monastier di Treviso 3
Monmouth Junction 3
New Bedfont 3
Oxford 3
Paullo 3
Pescara 3
Pisa 3
Priocca 3
Pune 3
Scandicci 3
Taizhou 3
Tappahannock 3
Toulouse 3
Vienna 3
Afragola 2
Totale 5.729
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Nome #
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T cell antigen receptor signaling to Ras family GTPases and Myc dependent survival 463
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape 280
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system 229
The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis 218
Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment 218
Analysis of TCR/CD3 recycling at the immune synapse 216
The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse 207
Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia 200
Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells 198
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes 186
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia 184
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 177
Lack of p66Shc in the CLL mouse model E mu-TCL1 exacerbates nodal and extranodal infiltration of leukemic cells which can undergo Richter's transformation 172
The Rab GTPase Rab8 as a shared regulator of ciliogenesis and immune synapse assembly: from a conserved pathway to diverse cellular structures 168
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T-cells 163
The CXCL12/CXCR4 Axis as a Therapeutic Target in Cancer and HIV-1 Infection 161
The B-side of the immune response 156
Nonsteroidal anti-inflammatory drugs inhibit a Fyn dependent pathway coupled to Rac and stress kinase activation in TCR signaling 152
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy 152
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis 151
Boosting chemokine receptor recycling: An elixir of life for chronic lymphocytic leukemia 151
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 151
Simvastatin inhibits T cell activation by selectively impairing the function of RAS superfamily GTPases 148
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays 148
Themis releases the brakes on TCR signaling during thymocyte selection by disabling SHP-1 145
The Glycerophosphoinositols: From Lipid Metabolites to Modulators of T-Cell Signaling 143
Intracellular mediators of CXCR4-dependent signaling in T-cells 142
Dysfunctional immune synapses in T cell immunodeficiencies 142
F-actin dynamics controls segregation of the TCR signaling cascade to clustered lipid rafts 137
Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases. 134
p66Shc-dependent apoptosis requires Lck and CaMKII activity 131
Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc 131
Defective Vav expression and impaired F-actin reorganization in a subset of common variable immunodeficiency patients with T-cell defects 121
Astrocyte deficiency of the Shc family member Rai attenuates myelin-reactive Th17 cell-dependent neurodegeneration in EAE: a mechanistic study of astrocyte-T cell interactions 119
Mucosal B cells 118
Anthrax toxins inhibit immune cell chemotaxis 117
The adenylate cyclase toxin of Bordetella pertussis binds to T cells via the integrin LFA-1 and induces its disengagement from the immune synapse 111
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling 110
Glycerophosphoinositol-4-phosphate enhances SDF-1?-stimulated T-cell chemotaxis through PTK-dependent activation of Vav 107
p66Shc promotes apoptosis and antagonises mitogenic signaling in T cells. 104
Fetal Myocardial Expression of GLUT1: Roles of BPA Exposure and Cord Blood Exosomes in a Rat Model 87
The Helicobacter pylori vacuolating toxin inhibits T-cell activation by two independent mechanisms 87
p66Shc promotes apoptosis and antagonises mitogenic signaling in T-cells 75
Anthrax toxins suppress immune cell activation and chemotaxis by perturbing receptor signaling 75
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia 73
p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB 70
P66shc: A pleiotropic regulator of B cell trafficking and a gatekeeper in chronic lymphocytic leukemia 69
Reduced p66Shc expression in Chronic lymphocytic leukemia (CLL) B cells enhances CXCR4/CCR7 recycling and impairs S1P1 expression promoting their lymph node accumulation 63
Regulation of lymphocyte trafficking by p66Shc: novel insight into CLL B cell survival 61
Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation 57
Nature vs. Nurture: The Two Opposing Behaviors of Cytotoxic T Lymphocytes in the Tumor Microenvironment 57
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 53
P66Shc deficiency promotes B cell chemotaxis by enhancing CXCR4 and CCR7 recycling in Chronic Lymphocytic Leukemia 50
Learning from TCR Signaling and Immunological Synapse Assembly to Build New Chimeric Antigen Receptors (CARs). 50
Negative regulation of chemokine receptor signalling and B cell chemotaxis by p66Shc 48
Interleukin (IL)-9 Supports the Tumor-Promoting Environment of Chronic Lymphocytic Leukemia 41
p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation 29
Rewiring the T cell-suppressive cytokine landscape of the tumor microenvironment: a new frontier for precision anti-cancer therapy 10
Totale 7.716
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Categoria #
all - tutte 24.697
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.697
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020788 0 0 0 0 109 111 103 151 113 100 33 68
2020/20211.091 59 73 29 76 98 111 51 159 105 143 108 79
2021/2022871 52 92 30 98 72 26 45 38 48 97 100 173
2022/20231.175 88 142 150 155 113 207 23 88 112 39 38 20
2023/20241.336 35 18 106 52 50 248 320 322 4 34 33 114
2024/2025505 47 106 195 120 37 0 0 0 0 0 0 0
Totale 7.716