IRIS
PATRUSSI, LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 6.562
EU - Europa 4.902
AS - Asia 2.373
SA - Sud America 395
AF - Africa 143
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 3
Totale 14.385
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Nazione #
US - Stati Uniti d'America 6.493
GB - Regno Unito 1.038
IT - Italia 1.022
RU - Federazione Russa 931
SG - Singapore 782
CN - Cina 731
IE - Irlanda 567
BR - Brasile 325
SE - Svezia 323
VN - Vietnam 289
FR - Francia 239
UA - Ucraina 211
DE - Germania 205
HK - Hong Kong 192
FI - Finlandia 148
KR - Corea 111
ZA - Sudafrica 66
IN - India 58
ES - Italia 39
NL - Olanda 39
JP - Giappone 35
AR - Argentina 31
CA - Canada 31
BD - Bangladesh 30
BE - Belgio 29
TR - Turchia 24
MX - Messico 22
IQ - Iraq 20
CI - Costa d'Avorio 19
CH - Svizzera 17
PL - Polonia 17
AT - Austria 16
NG - Nigeria 14
PK - Pakistan 14
CZ - Repubblica Ceca 13
IR - Iran 13
EC - Ecuador 12
VE - Venezuela 10
KE - Kenya 9
UZ - Uzbekistan 9
DZ - Algeria 8
ID - Indonesia 8
AU - Australia 7
CO - Colombia 7
LT - Lituania 7
MA - Marocco 7
DK - Danimarca 6
EG - Egitto 6
JO - Giordania 6
TN - Tunisia 6
AL - Albania 5
GR - Grecia 5
IL - Israele 5
KG - Kirghizistan 5
HU - Ungheria 4
KZ - Kazakistan 4
MY - Malesia 4
PA - Panama 4
PE - Perù 4
PH - Filippine 4
SA - Arabia Saudita 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
ET - Etiopia 3
EU - Europa 3
GE - Georgia 3
JM - Giamaica 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
TW - Taiwan 3
AO - Angola 2
BH - Bahrain 2
CL - Cile 2
DO - Repubblica Dominicana 2
LK - Sri Lanka 2
LU - Lussemburgo 2
MD - Moldavia 2
NP - Nepal 2
SI - Slovenia 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BO - Bolivia 1
BY - Bielorussia 1
CM - Camerun 1
CR - Costa Rica 1
EE - Estonia 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
MK - Macedonia 1
NI - Nicaragua 1
NO - Norvegia 1
OM - Oman 1
PS - Palestinian Territory 1
PY - Paraguay 1
Totale 14.378
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Città #
Dallas 1.815
Southend 908
Ashburn 676
Dublin 558
Singapore 497
Fairfield 440
Menlo Park 360
Chandler 305
Moscow 262
Siena 253
Santa Clara 242
Woodbridge 204
Seattle 179
Hong Kong 178
Ann Arbor 176
Wilmington 171
Jacksonville 169
San Jose 168
Beijing 160
Hefei 155
Houston 152
Florence 139
Cambridge 135
Seoul 109
Milan 93
Princeton 93
Ho Chi Minh City 88
The Dalles 88
Helsinki 87
Los Angeles 81
Council Bluffs 68
Nanjing 62
Johannesburg 61
New York 60
Lauterbourg 58
Hanoi 54
Rome 45
Munich 44
Dong Ket 43
Shanghai 39
Dearborn 35
Boardman 32
San Diego 29
Buffalo 28
São Paulo 28
Brussels 27
London 26
Málaga 26
San Mateo 24
Columbus 22
Frankfurt am Main 22
Bengaluru 21
Orem 20
Shenyang 20
Abidjan 19
Fremont 17
Redondo Beach 17
Tokyo 17
Chicago 16
Lappeenranta 16
Nanchang 16
Turku 16
Rio de Janeiro 15
Lancaster 14
Redwood City 14
Abuja 13
Amsterdam 13
Haiphong 13
Phoenix 12
San Francisco 12
Warsaw 12
Brasília 11
Da Nang 11
Düsseldorf 11
Nuremberg 11
Poplar 11
Kunming 10
Nagareyama 10
Norwalk 10
Stockholm 10
Venezia 10
Vienna 10
Brno 9
Chennai 9
Denver 9
Greve in Chianti 9
Jinan 9
Mexico City 9
Montreal 9
Naples 9
Prato 9
Tashkent 9
Toronto 9
Hebei 8
Hải Dương 8
Jiaxing 8
Lausanne 8
Padova 8
Atlanta 7
Baghdad 7
Totale 10.355
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Nome #
Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles 1.170
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T cell antigen receptor signaling to Ras family GTPases and Myc dependent survival 631
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape 388
Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment 344
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 330
Analysis of TCR/CD3 recycling at the immune synapse 330
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system 324
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 309
Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells 297
The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis 295
The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse 290
Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia 289
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia 289
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia 275
F-actin dynamics controls segregation of the TCR signaling cascade to clustered lipid rafts 270
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes 269
Astrocyte deficiency of the Shc family member Rai attenuates myelin-reactive Th17 cell-dependent neurodegeneration in EAE: a mechanistic study of astrocyte-T cell interactions 267
The Rab GTPase Rab8 as a shared regulator of ciliogenesis and immune synapse assembly: from a conserved pathway to diverse cellular structures 263
Lack of p66Shc in the CLL mouse model E mu-TCL1 exacerbates nodal and extranodal infiltration of leukemic cells which can undergo Richter's transformation 253
Dysfunctional immune synapses in T cell immunodeficiencies 252
Anthrax toxins inhibit immune cell chemotaxis 246
An AMBRA1, ULK1 and PP2A regulatory network regulates cytotoxic T cell differentiation via TFEB activation 243
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T-cells 240
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 240
Simvastatin inhibits T cell activation by selectively impairing the function of RAS superfamily GTPases 233
Boosting chemokine receptor recycling: An elixir of life for chronic lymphocytic leukemia 222
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis 220
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays 219
Nonsteroidal anti-inflammatory drugs inhibit a Fyn dependent pathway coupled to Rac and stress kinase activation in TCR signaling 218
The B-side of the immune response 218
The CXCL12/CXCR4 Axis as a Therapeutic Target in Cancer and HIV-1 Infection 217
Defective Vav expression and impaired F-actin reorganization in a subset of common variable immunodeficiency patients with T-cell defects 210
Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases. 209
Fetal Myocardial Expression of GLUT1: Roles of BPA Exposure and Cord Blood Exosomes in a Rat Model 208
p66Shc-dependent apoptosis requires Lck and CaMKII activity 208
The adenylate cyclase toxin of Bordetella pertussis binds to T cells via the integrin LFA-1 and induces its disengagement from the immune synapse 202
The Glycerophosphoinositols: From Lipid Metabolites to Modulators of T-Cell Signaling 201
Glycerophosphoinositol-4-phosphate enhances SDF-1?-stimulated T-cell chemotaxis through PTK-dependent activation of Vav 196
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy 196
Intracellular mediators of CXCR4-dependent signaling in T-cells 191
Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation 188
Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc 188
Anthrax toxins suppress immune cell activation and chemotaxis by perturbing receptor signaling 184
Themis releases the brakes on TCR signaling during thymocyte selection by disabling SHP-1 181
Mucosal B cells 178
p66Shc promotes apoptosis and antagonises mitogenic signaling in T cells. 176
p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB 170
Learning from TCR Signaling and Immunological Synapse Assembly to Build New Chimeric Antigen Receptors (CARs). 166
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling 159
Rewiring the T cell-suppressive cytokine landscape of the tumor microenvironment: a new frontier for precision anti-cancer therapy 158
p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation 158
The Helicobacter pylori vacuolating toxin inhibits T-cell activation by two independent mechanisms 156
P66shc: A pleiotropic regulator of B cell trafficking and a gatekeeper in chronic lymphocytic leukemia 134
p66Shc promotes apoptosis and antagonises mitogenic signaling in T-cells 132
Nature vs. Nurture: The Two Opposing Behaviors of Cytotoxic T Lymphocytes in the Tumor Microenvironment 131
Interleukin (IL)-9 Supports the Tumor-Promoting Environment of Chronic Lymphocytic Leukemia 128
P66Shc deficiency promotes B cell chemotaxis by enhancing CXCR4 and CCR7 recycling in Chronic Lymphocytic Leukemia 114
Reduced p66Shc expression in Chronic lymphocytic leukemia (CLL) B cells enhances CXCR4/CCR7 recycling and impairs S1P1 expression promoting their lymph node accumulation 113
Negative regulation of chemokine receptor signalling and B cell chemotaxis by p66Shc 111
Regulation of lymphocyte trafficking by p66Shc: novel insight into CLL B cell survival 104
IFT20 regulates TFEB-dependent lytic granule biogenesis in cytotoxic T lymphocytes by orchestrating the MPR-dependent transport of granzyme B 89
Totale 14.590
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Categoria #
all - tutte 40.051
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.051
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021330 0 0 0 0 0 0 0 0 0 143 108 79
2021/2022871 52 92 30 98 72 26 45 38 48 97 100 173
2022/20231.175 88 142 150 155 113 207 23 88 112 39 38 20
2023/20241.336 35 18 106 52 50 248 320 322 4 34 33 114
2024/20251.944 47 106 195 120 244 200 88 125 131 84 195 409
2025/20265.435 349 1.721 675 532 954 154 546 153 173 178 0 0
Totale 14.590