PATRUSSI, LAURA
 Distribuzione geografica
Continente #
NA - Nord America 3.890
EU - Europa 3.755
AS - Asia 635
SA - Sud America 117
AF - Africa 28
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 8.432
Nazione #
US - Stati Uniti d'America 3.872
GB - Regno Unito 991
IT - Italia 869
IE - Irlanda 563
SE - Svezia 316
CN - Cina 305
RU - Federazione Russa 225
UA - Ucraina 206
SG - Singapore 199
FR - Francia 167
DE - Germania 158
BR - Brasile 107
FI - Finlandia 103
VN - Vietnam 44
ES - Italia 32
BE - Belgio 29
NL - Olanda 23
CI - Costa d'Avorio 17
AT - Austria 14
JP - Giappone 14
TR - Turchia 14
CH - Svizzera 13
CZ - Repubblica Ceca 13
CA - Canada 12
HK - Hong Kong 10
IR - Iran 10
IN - India 7
AR - Argentina 5
DK - Danimarca 5
GR - Grecia 5
AU - Australia 4
EG - Egitto 4
MA - Marocco 4
EC - Ecuador 3
EU - Europa 3
IL - Israele 3
IQ - Iraq 3
KG - Kirghizistan 3
PA - Panama 3
PK - Pakistan 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
TW - Taiwan 3
AL - Albania 2
BD - Bangladesh 2
HU - Ungheria 2
KZ - Kazakistan 2
LK - Sri Lanka 2
LU - Lussemburgo 2
PL - Polonia 2
UZ - Uzbekistan 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
CO - Colombia 1
CR - Costa Rica 1
DZ - Algeria 1
EE - Estonia 1
ID - Indonesia 1
JM - Giamaica 1
JO - Giordania 1
KR - Corea 1
LA - Repubblica Popolare Democratica del Laos 1
LT - Lituania 1
LV - Lettonia 1
MD - Moldavia 1
MX - Messico 1
MY - Malesia 1
RO - Romania 1
RS - Serbia 1
SA - Arabia Saudita 1
SI - Slovenia 1
TH - Thailandia 1
TN - Tunisia 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 8.432
Città #
Southend 908
Dublin 555
Ashburn 550
Fairfield 440
Menlo Park 360
Chandler 305
Siena 251
Santa Clara 235
Woodbridge 204
Ann Arbor 176
Seattle 176
Wilmington 171
Jacksonville 169
Houston 148
Cambridge 135
Florence 116
Singapore 101
Princeton 93
Helsinki 66
Nanjing 61
Milan 52
Beijing 48
Dong Ket 43
New York 40
Rome 37
Shanghai 37
Dearborn 35
Boardman 29
Moscow 29
San Diego 28
Brussels 27
Málaga 26
San Mateo 24
Council Bluffs 22
Munich 20
Shenyang 20
Abidjan 17
Fremont 17
Nanchang 16
Los Angeles 15
Redwood City 14
Lancaster 13
London 13
Düsseldorf 11
Hefei 11
The Dalles 11
Kunming 10
Nagareyama 10
Norwalk 10
Venezia 10
Brno 9
Columbus 9
Greve in Chianti 9
Nuremberg 9
Prato 9
Hebei 8
Hong Kong 8
Jiaxing 8
Lausanne 8
Padova 8
São Paulo 8
Vienna 8
Brescia 7
Frankfurt am Main 7
Lauterbourg 7
Mestre 7
Phoenix 7
Bacoli 6
Dallas 6
Izmir 6
Jinan 6
Naples 6
Ningbo 6
San Francisco 6
Schoenebeck 6
Tianjin 6
Bergamo 5
Lappeenranta 5
Merate 5
Scarperia 5
Toronto 5
Washington 5
Amsterdam 4
Cairo 4
Hangzhou 4
Inverigo 4
Kilburn 4
Marano di Napoli 4
Perugia 4
Taizhou 4
Anguillara Sabazia 3
Atlanta 3
Azzate 3
Bari 3
Bishkek 3
Brasília 3
Canberra 3
Cantagallo 3
Copenhagen 3
Curitiba 3
Totale 6.197
Nome #
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T cell antigen receptor signaling to Ras family GTPases and Myc dependent survival 474
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape 298
Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment 241
The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis 236
Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system 236
Analysis of TCR/CD3 recycling at the immune synapse 231
The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse 223
Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia 212
Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells 211
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia 199
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes 195
Lack of p66Shc in the CLL mouse model E mu-TCL1 exacerbates nodal and extranodal infiltration of leukemic cells which can undergo Richter's transformation 191
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 188
The Rab GTPase Rab8 as a shared regulator of ciliogenesis and immune synapse assembly: from a conserved pathway to diverse cellular structures 180
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 178
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T-cells 177
The CXCL12/CXCR4 Axis as a Therapeutic Target in Cancer and HIV-1 Infection 169
Nonsteroidal anti-inflammatory drugs inhibit a Fyn dependent pathway coupled to Rac and stress kinase activation in TCR signaling 165
Simvastatin inhibits T cell activation by selectively impairing the function of RAS superfamily GTPases 162
The B-side of the immune response 162
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy 161
Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays 161
Boosting chemokine receptor recycling: An elixir of life for chronic lymphocytic leukemia 158
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis 157
Dysfunctional immune synapses in T cell immunodeficiencies 157
F-actin dynamics controls segregation of the TCR signaling cascade to clustered lipid rafts 153
Themis releases the brakes on TCR signaling during thymocyte selection by disabling SHP-1 152
The Glycerophosphoinositols: From Lipid Metabolites to Modulators of T-Cell Signaling 150
Intracellular mediators of CXCR4-dependent signaling in T-cells 148
p66Shc-dependent apoptosis requires Lck and CaMKII activity 144
Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases. 143
Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc 139
Defective Vav expression and impaired F-actin reorganization in a subset of common variable immunodeficiency patients with T-cell defects 135
Astrocyte deficiency of the Shc family member Rai attenuates myelin-reactive Th17 cell-dependent neurodegeneration in EAE: a mechanistic study of astrocyte-T cell interactions 135
Mucosal B cells 127
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia 125
The adenylate cyclase toxin of Bordetella pertussis binds to T cells via the integrin LFA-1 and induces its disengagement from the immune synapse 124
Anthrax toxins inhibit immune cell chemotaxis 124
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling 119
p66Shc promotes apoptosis and antagonises mitogenic signaling in T cells. 117
Glycerophosphoinositol-4-phosphate enhances SDF-1?-stimulated T-cell chemotaxis through PTK-dependent activation of Vav 114
Fetal Myocardial Expression of GLUT1: Roles of BPA Exposure and Cord Blood Exosomes in a Rat Model 106
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients 97
The Helicobacter pylori vacuolating toxin inhibits T-cell activation by two independent mechanisms 94
p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB 94
An AMBRA1, ULK1 and PP2A regulatory network regulates cytotoxic T cell differentiation via TFEB activation 92
Anthrax toxins suppress immune cell activation and chemotaxis by perturbing receptor signaling 85
p66Shc promotes apoptosis and antagonises mitogenic signaling in T-cells 84
Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation 78
P66shc: A pleiotropic regulator of B cell trafficking and a gatekeeper in chronic lymphocytic leukemia 78
Learning from TCR Signaling and Immunological Synapse Assembly to Build New Chimeric Antigen Receptors (CARs). 76
p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation 70
Regulation of lymphocyte trafficking by p66Shc: novel insight into CLL B cell survival 70
Reduced p66Shc expression in Chronic lymphocytic leukemia (CLL) B cells enhances CXCR4/CCR7 recycling and impairs S1P1 expression promoting their lymph node accumulation 69
Nature vs. Nurture: The Two Opposing Behaviors of Cytotoxic T Lymphocytes in the Tumor Microenvironment 63
P66Shc deficiency promotes B cell chemotaxis by enhancing CXCR4 and CCR7 recycling in Chronic Lymphocytic Leukemia 58
Negative regulation of chemokine receptor signalling and B cell chemotaxis by p66Shc 56
Interleukin (IL)-9 Supports the Tumor-Promoting Environment of Chronic Lymphocytic Leukemia 54
Rewiring the T cell-suppressive cytokine landscape of the tumor microenvironment: a new frontier for precision anti-cancer therapy 36
Totale 8.631
Categoria #
all - tutte 29.080
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.080


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020101 0 0 0 0 0 0 0 0 0 0 33 68
2020/20211.091 59 73 29 76 98 111 51 159 105 143 108 79
2021/2022871 52 92 30 98 72 26 45 38 48 97 100 173
2022/20231.175 88 142 150 155 113 207 23 88 112 39 38 20
2023/20241.336 35 18 106 52 50 248 320 322 4 34 33 114
2024/20251.420 47 106 195 120 244 200 88 125 131 84 80 0
Totale 8.631