The syntheses of some 3-substituted-2-(4-methyl-1-piperazinyl)4-phenylquinolines are reported. The title compounds were tested for their potential activities on 5-HT receptor subtypes and 5-HT uptake site; compounds 4b-d showed micromolar affinity for 5-HT3 and 5-HT uptake site.
Anzini, M., Cappelli, A., Vomero, S., Campiani, G., Cagnotto, A., Skorupska, M. (1991). Synthesis and 5-HT Receptors Binding Studies of Some 3-Substituted-2-(4-methyl-1-piperazinyl)-4-phenylquinolines. IL FARMACO, 46(12), 1435-1447.
Synthesis and 5-HT Receptors Binding Studies of Some 3-Substituted-2-(4-methyl-1-piperazinyl)-4-phenylquinolines
Anzini M.;Cappelli A.;Vomero S.;Campiani G.;
1991-01-01
Abstract
The syntheses of some 3-substituted-2-(4-methyl-1-piperazinyl)4-phenylquinolines are reported. The title compounds were tested for their potential activities on 5-HT receptor subtypes and 5-HT uptake site; compounds 4b-d showed micromolar affinity for 5-HT3 and 5-HT uptake site.
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https://hdl.handle.net/11365/8235
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