OBJECTIVE: To evaluate the pregnancy outcome in women >30 years old with uterine fibroids also considering other possible concomitant risk factors. METHODS: A multicentric, observational and retrospective study was conducted. All women were asked to complete a questionnaire while they were in hospital and the outcome of pregnancy was investigated. RESULTS: Women with uterine fibroids before pregnancy were more frequently >35 years old and in their clinical history before pregnancy showed more pelvic pain, polliachiuria, previous pelvic surgery, hypermenorrhea and dysmenorrhea, than control women (p < 0.0001). During pregnancy patients with uterine fibroids showed significantly more threatened preterm birth (PTB) and PTB, weight gain, hyperemesis, gestational hypertension and post-partum bleeding and showed more often requirement for emergency cesarean section (p < 0.0001). The multivariate logistic regression model used for evaluating the effect of clinical parameters on outcome of pregnancy showed that age >35 years, pelvic pain, work, weight gain, hyperemesis, threatened miscarriage and threatened PTB were significantly correlated with unfavorable pregnancy outcome , independently of the presence of uterine fibroids (p < 0.0001). CONCLUSIONS: The present study confirming a more frequent negative pregnancy outcome in presence of uterine fibroids, showed that other risk factors may affect pregnancy and delivery outcome in women aging >30 years old.

Conti, N., Tosti, C., Pinzauti, S., Tomaiuolo, T., Cevenini, G., Severi, F.M., et al. (2013). Uterine fibroids affect pregnancy outcome in women over 30 years old: role of other risk factors. THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 26(6), 584-587 [10.3109/14767058.2012.745504].

Uterine fibroids affect pregnancy outcome in women over 30 years old: role of other risk factors

Conti, N.;Tosti, C.;Pinzauti, S.;Cevenini, G.;Severi, F. M.;Di Tommaso, M.;Petraglia, F.
2013

Abstract

OBJECTIVE: To evaluate the pregnancy outcome in women >30 years old with uterine fibroids also considering other possible concomitant risk factors. METHODS: A multicentric, observational and retrospective study was conducted. All women were asked to complete a questionnaire while they were in hospital and the outcome of pregnancy was investigated. RESULTS: Women with uterine fibroids before pregnancy were more frequently >35 years old and in their clinical history before pregnancy showed more pelvic pain, polliachiuria, previous pelvic surgery, hypermenorrhea and dysmenorrhea, than control women (p < 0.0001). During pregnancy patients with uterine fibroids showed significantly more threatened preterm birth (PTB) and PTB, weight gain, hyperemesis, gestational hypertension and post-partum bleeding and showed more often requirement for emergency cesarean section (p < 0.0001). The multivariate logistic regression model used for evaluating the effect of clinical parameters on outcome of pregnancy showed that age >35 years, pelvic pain, work, weight gain, hyperemesis, threatened miscarriage and threatened PTB were significantly correlated with unfavorable pregnancy outcome , independently of the presence of uterine fibroids (p < 0.0001). CONCLUSIONS: The present study confirming a more frequent negative pregnancy outcome in presence of uterine fibroids, showed that other risk factors may affect pregnancy and delivery outcome in women aging >30 years old.
Conti, N., Tosti, C., Pinzauti, S., Tomaiuolo, T., Cevenini, G., Severi, F.M., et al. (2013). Uterine fibroids affect pregnancy outcome in women over 30 years old: role of other risk factors. THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 26(6), 584-587 [10.3109/14767058.2012.745504].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/46109
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