A series of 2-arylpyrazolo[4,3-c] quinolin-3-one derivatives, bearing different substituents in the two aromatic rings, were prepared and tested for their ability to displace [H-3] flunitrazepam from rat brain membranes. Some compounds have shown an affinity for receptors comparable and sometimes higher than that of CGS series.

Savini, L., Massarelli, P., Pellerano, C., Fiorini, I., Bruni, G., & Romeo, M.R. (1993). Pyrazolo[4,3-c]quinolines. Synthesis and specific inhibition of benzodiazepine receptor binding (Note I). IL FARMACO, 48(1), 65-76.

Pyrazolo[4,3-c]quinolines. Synthesis and specific inhibition of benzodiazepine receptor binding (Note I)

SAVINI, LUISA;MASSARELLI, PAOLA;PELLERANO, CESARE;FIORINI, ISABELLA;BRUNI, GIANCARLO;
1993

Abstract

A series of 2-arylpyrazolo[4,3-c] quinolin-3-one derivatives, bearing different substituents in the two aromatic rings, were prepared and tested for their ability to displace [H-3] flunitrazepam from rat brain membranes. Some compounds have shown an affinity for receptors comparable and sometimes higher than that of CGS series.
Savini, L., Massarelli, P., Pellerano, C., Fiorini, I., Bruni, G., & Romeo, M.R. (1993). Pyrazolo[4,3-c]quinolines. Synthesis and specific inhibition of benzodiazepine receptor binding (Note I). IL FARMACO, 48(1), 65-76.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/402195
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