In a previous paper, we showed inhibition of rat liver L-threonine dehydrogenase by a preparation obtained by dialysis and concentration from rat liver mitochondria stored at -20 degrees C for 7-10 days (Pagani, R., Leoncini, R., Guerranti, R. and Marinello, E. (1990) It. J. Biochem. 39, 106-114). The chemical composition of the fraction containing the unknown 'inhibitor' has now been studied and identified as D-3-hydroxybutyrate (D3HB).
Pagani, R., Guerranti, R., Righi, S., Lazzeretti, L., Leoncini, R., Marinello, E., et al. (1995). Identification of a mitochondrial inhibitor of rat liver L-threonine dehydrogenase. BIOCHIMICA ET BIOPHYSICA ACTA, 1244(1), 49-52 [10.1016/0304-4165(94)00192-Z].
Identification of a mitochondrial inhibitor of rat liver L-threonine dehydrogenase
Pagani R.;Guerranti R.;Leoncini R.;Marinello E.;Pizzichini M.
1995-01-01
Abstract
In a previous paper, we showed inhibition of rat liver L-threonine dehydrogenase by a preparation obtained by dialysis and concentration from rat liver mitochondria stored at -20 degrees C for 7-10 days (Pagani, R., Leoncini, R., Guerranti, R. and Marinello, E. (1990) It. J. Biochem. 39, 106-114). The chemical composition of the fraction containing the unknown 'inhibitor' has now been studied and identified as D-3-hydroxybutyrate (D3HB).
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https://hdl.handle.net/11365/37388
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