The use of BAL to study ILDs has improved our understanding of IPF pathogenesis. BAL fluid is routinely collected and can be considered a clinical and research tool. The procedure is well tolerated and minimally invasive. No specific cell lines from BAL or immortalized cell lines from IPF patients are available commercially. A method to quickly isolate and characterize fibroblasts from BAL is an unmet research need.
Bergantini, L., D'Alessandro, M., Gangi, S., Cavallaro, D., Campiani, G., Butini, S., et al. (2022). Bronchoalveolar-Lavage-Derived Fibroblast Cell Line (B-LSDM7) as a new protocol for investigating the mechanisms of idiopathic pulmonary fibrosis. CELLS, 11(9) [10.3390/cells11091441].
Bronchoalveolar-Lavage-Derived Fibroblast Cell Line (B-LSDM7) as a new protocol for investigating the mechanisms of idiopathic pulmonary fibrosis
Bergantini, Laura;d'Alessandro, Miriana;Gangi, Sara;Campiani, Giuseppe;Butini, Stefania;Landi, Claudia;Bini, Luca;Cameli, Paolo;Bargagli, Elena
2022-01-01
Abstract
The use of BAL to study ILDs has improved our understanding of IPF pathogenesis. BAL fluid is routinely collected and can be considered a clinical and research tool. The procedure is well tolerated and minimally invasive. No specific cell lines from BAL or immortalized cell lines from IPF patients are available commercially. A method to quickly isolate and characterize fibroblasts from BAL is an unmet research need.
| File | Dimensione | Formato | |
|---|---|---|---|
|
bronchoalveolar cells-11-01441.pdf
accesso aperto
Descrizione: Articolo
Tipologia:
PDF editoriale
Licenza:
Creative commons
Dimensione
5.43 MB
Formato
Adobe PDF
|
5.43 MB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/1212254