The use of BAL to study ILDs has improved our understanding of IPF pathogenesis. BAL fluid is routinely collected and can be considered a clinical and research tool. The procedure is well tolerated and minimally invasive. No specific cell lines from BAL or immortalized cell lines from IPF patients are available commercially. A method to quickly isolate and characterize fibroblasts from BAL is an unmet research need.

Bergantini, L., D'Alessandro, M., Gangi, S., Cavallaro, D., Campiani, G., Butini, S., et al. (2022). Bronchoalveolar-Lavage-Derived Fibroblast Cell Line (B-LSDM7) as a New Protocol for Investigating the Mechanisms of Idiopathic Pulmonary Fibrosis. CELLS, 11(9), 1441 [10.3390/cells11091441].

Bronchoalveolar-Lavage-Derived Fibroblast Cell Line (B-LSDM7) as a New Protocol for Investigating the Mechanisms of Idiopathic Pulmonary Fibrosis

Bergantini, Laura;d'Alessandro, Miriana;Gangi, Sara;Cavallaro, Dalila;Campiani, Giuseppe;Butini, Stefania;Landi, Claudia;Bini, Luca;Cameli, Paolo;Bargagli, Elena
2022-01-01

Abstract

The use of BAL to study ILDs has improved our understanding of IPF pathogenesis. BAL fluid is routinely collected and can be considered a clinical and research tool. The procedure is well tolerated and minimally invasive. No specific cell lines from BAL or immortalized cell lines from IPF patients are available commercially. A method to quickly isolate and characterize fibroblasts from BAL is an unmet research need.
Bergantini, L., D'Alessandro, M., Gangi, S., Cavallaro, D., Campiani, G., Butini, S., et al. (2022). Bronchoalveolar-Lavage-Derived Fibroblast Cell Line (B-LSDM7) as a New Protocol for Investigating the Mechanisms of Idiopathic Pulmonary Fibrosis. CELLS, 11(9), 1441 [10.3390/cells11091441].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/1212254
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