IRIS
BENVENUTI, MANUELA
 Distribuzione geografica
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Continente #
EU - Europa 2.644
NA - Nord America 2.595
AS - Asia 412
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 4
AF - Africa 1
SA - Sud America 1
Totale 5.665
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Nazione #
US - Stati Uniti d'America 2.589
GB - Regno Unito 789
IE - Irlanda 555
CN - Cina 364
IT - Italia 302
UA - Ucraina 294
SE - Svezia 256
DE - Germania 160
FR - Francia 129
FI - Finlandia 96
VN - Vietnam 21
BE - Belgio 14
IN - India 10
RU - Federazione Russa 10
PL - Polonia 8
AU - Australia 7
AT - Austria 4
CA - Canada 4
EU - Europa 4
NL - Olanda 4
CH - Svizzera 3
GR - Grecia 3
LU - Lussemburgo 3
ES - Italia 2
HK - Hong Kong 2
HR - Croazia 2
HU - Ungheria 2
JP - Giappone 2
KR - Corea 2
MK - Macedonia 2
PH - Filippine 2
PT - Portogallo 2
SG - Singapore 2
AL - Albania 1
BG - Bulgaria 1
CL - Cile 1
DO - Repubblica Dominicana 1
EG - Egitto 1
ID - Indonesia 1
IR - Iran 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
MD - Moldavia 1
NZ - Nuova Zelanda 1
PA - Panama 1
RO - Romania 1
SA - Arabia Saudita 1
TR - Turchia 1
TW - Taiwan 1
Totale 5.665
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Città #
Southend 712
Dublin 555
Chandler 305
Fairfield 305
Jacksonville 241
Woodbridge 167
Ashburn 166
Wilmington 137
Cambridge 112
Seattle 112
Houston 111
Princeton 109
Ann Arbor 101
Siena 89
Menlo Park 87
Nanjing 87
Beijing 73
Fremont 55
Helsinki 46
Boardman 41
San Mateo 37
New York 35
San Diego 35
Sesto Fiorentino 33
Nanchang 28
Dong Ket 21
Shanghai 21
London 17
Shenyang 17
Venezia 17
Changsha 15
Florence 15
Lancaster 15
Brussels 14
Jiaxing 14
Kunming 14
Tianjin 14
Jinan 11
Norwalk 10
Düsseldorf 9
San Francisco 9
Zhengzhou 9
Hangzhou 8
Hebei 8
West Jordan 8
Dearborn 7
Milan 7
Ningbo 7
Gdynia 6
Guangzhou 5
Taizhou 5
Auburn Hills 4
Haikou 4
Philadelphia 4
Pisa 4
Pontedera 4
Redwood City 4
Rome 4
Vienna 4
Canberra 3
Changchun 3
Edinburgh 3
Hanover 3
Hefei 3
Kilburn 3
Luxembourg 3
Moscow 3
Nuremberg 3
Prato 3
Roorkee 3
Tappahannock 3
Torino 3
Acton 2
Almada 2
Amsterdam 2
Athens 2
Atlanta 2
Bari 2
Bitonto 2
Bologna 2
Budapest 2
Campi Bisenzio 2
Caselle Torinese 2
Columbus 2
Corbetta 2
Dobong-gu 2
Fort Worth 2
Indore 2
Irvine 2
Islington 2
Las Vegas 2
Livorno 2
Lucca 2
Mestre 2
Montale 2
Ponte A Égola 2
Prescot 2
Pune 2
San Giovanni Valdarno 2
Seveso 2
Totale 4.209
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Nome #
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model 153
VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- And metallo-β-lactamases, restores activity of cefepime in enterobacterales and Pseudomonas aeruginosa 134
Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem 133
X-ray Crystal Structure of the Acinetobacter baumannii OXA-24/40 Class D Carbapenemase Inhibited by NXL104 132
Crystal structure of AphA class B acid phosphatase/phosphotransferase from E. coli 130
Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam 130
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease 128
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- And Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections 128
Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam. 126
The structure of the human glutaminyl cyclase–SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders 126
A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases 124
null 120
Crystallization of soluble proteins in vapor diffusion for x-ray crystallography 118
Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design 118
Structural characterisation of a new heparinisable material based on ethylene/vinyl alcohol/vinyl acetate terpolymer and a poly(amido-amine) 118
Crystallization and preliminary crystallographic analysis of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E: a novel dioxygenase involved in the biodegradation of polychlorinated aromatic compounds 118
XAS of dilute biological samples 116
Sulfated hyaluronic acid as heparin-like material: physicochemical and biological characterization 115
Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC  beta-Lactamases 111
The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction 109
Sulfated hyaluronic acid as heparin-like material: physico-chemical and biological characterization 107
From an inactive prokaryotic SOD homologue to an active protein through site-directed mutagenesis 107
The soluble Y115E-Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease 107
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. Evidence for a dinuclear zinc site 107
Evolution to carbapenem -hydrolyzing activity in noncarbapenemase class D beta-lactamase OXA-10 by rational protein design 106
Structural Insights into the Catalytic Mechanism of the Bacterial Class B Phosphatase AphA Belonging to the DDDD Superfamily of Phosphohydrolases 103
The first structure of a bacterial class B acid phosphatase reveals further structural heterogeneity among phosphatases of the haloacid dehalogenase fold 103
Sulfated hyaluronic acid as heparin-like material: physico-chemical and biological characterization 102
High-Resolution Crystal Structure of the Subclass B3 Metallo-beta-Lactamase BJP-1: Rational Basis for Substrate Specificity and Interaction with Sulfonamides 102
Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases 101
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates 101
Crystal structure and mutational analysis of FUS-1 (OXA-85), a class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum 100
ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae 96
Structure of the extended-spectrum beta-lactamase TEM-72 inhibited by citrate 89
Preparation, physico-chemical and biological characterization of heparinizable materials 88
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors 88
Structural and functional characterization of two new class D beta-lactamases: OXA-46 and OXA-48 85
Metallo-enzyme mechanism from accurate structural data 83
Crystal structure of Enterococcus faecalis Thymidylate synthase 83
New trends in blood compatible materials 83
Acid-base properties and complexing abilities of an aminodicarboxylic acid and its corresponding polymer 83
Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii 83
Evolution to carbapenem-hydrolyzing activity in class D β-lactamases by rational protein design. 80
Derivati solfatati dell'acido ialuronico come prodotto eparino-simili: caratterizzazione chimico-fisica e biologica 78
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity 69
Adsorption of metal ions from sulphuric acid solution by chelating resins 69
Crystallographic studies of new human Thymidylate synthase inhibitors 67
Expression, purification, crystallization and preliminary X-ray characterization of the class B acid phosphatase (AphA) from Escherichia coli 67
Materials containing heparin complexing polymers, physicochemical characterization and compatibility 66
1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors 65
Crystallographic studies of new human Thymidylate synthase inhibitors. 64
Crystallographic studies of new human Thymidylate synthase inhibitors 64
Derivati solfatati dell'acido ialuronico come prodotti eparino-simili: caratterizzazione chimico-fisica e biologica 60
Synthesis of two novel heparinizable polymeric materials (EVAPA-45 and EVAPA) for hemodialysis membranes 55
Calorimetric study of macromolecular complex formation between heparin and poly(amido-amine)s. 55
null 54
Synthesis of two novel heparinizable polymeric materials starting from an ethylene/vinyl alcohol/vinyl acetate terpolymer 54
New macromolecular ligands. Basicity and complexing properties of monomeric and polymeric dicarboxylic aminoacids 46
Synthesis and chemical characterization: characterization of biomaterials in contact with blood 44
Large size chelate rings in copper(II) complexes with triamine 40
Structural and functional characterization of two new class D beta-lactamase: OXA-46 and OXA-48 39
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates 20
Totale 5.750
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Categoria #
all - tutte 17.540
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.540
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019251 0 0 0 0 0 0 0 0 0 0 119 132
2019/20201.043 166 35 73 151 62 56 79 138 94 92 24 73
2020/2021973 32 98 22 72 76 141 38 157 120 77 56 84
2021/2022771 38 99 69 49 79 27 34 39 27 78 62 170
2022/20231.080 70 77 128 136 116 238 17 104 131 12 27 24
2023/2024767 43 16 60 34 53 206 292 24 2 30 7 0
Totale 5.750