IRIS
BENVENUTI, MANUELA
 Distribuzione geografica
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Continente #
NA - Nord America 18.476
EU - Europa 3.936
AS - Asia 2.133
SA - Sud America 400
AF - Africa 90
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 4
Totale 25.049
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Nazione #
US - Stati Uniti d'America 18.409
GB - Regno Unito 849
CN - Cina 815
RU - Federazione Russa 712
SG - Singapore 568
IE - Irlanda 556
IT - Italia 540
BR - Brasile 333
UA - Ucraina 293
SE - Svezia 263
HK - Hong Kong 231
DE - Germania 227
FR - Francia 216
VN - Vietnam 199
FI - Finlandia 110
KR - Corea 87
IN - India 55
ZA - Sudafrica 41
NL - Olanda 35
PL - Polonia 28
CA - Canada 27
AR - Argentina 24
IQ - Iraq 22
CZ - Repubblica Ceca 21
BE - Belgio 19
BD - Bangladesh 18
MX - Messico 17
ID - Indonesia 16
JP - Giappone 15
AT - Austria 14
TR - Turchia 14
PK - Pakistan 13
CI - Costa d'Avorio 12
AU - Australia 9
CL - Cile 9
UZ - Uzbekistan 9
VE - Venezuela 9
EC - Ecuador 8
JM - Giamaica 8
JO - Giordania 8
NP - Nepal 8
PH - Filippine 8
CH - Svizzera 7
ES - Italia 7
NG - Nigeria 7
EG - Egitto 6
PT - Portogallo 6
SA - Arabia Saudita 6
TN - Tunisia 6
DO - Repubblica Dominicana 5
GR - Grecia 5
IR - Iran 5
MY - Malesia 5
BO - Bolivia 4
CO - Colombia 4
EU - Europa 4
KE - Kenya 4
MA - Marocco 4
PY - Paraguay 4
TW - Taiwan 4
AZ - Azerbaigian 3
HR - Croazia 3
HU - Ungheria 3
IL - Israele 3
LT - Lituania 3
LU - Lussemburgo 3
NI - Nicaragua 3
OM - Oman 3
PA - Panama 3
PE - Perù 3
AL - Albania 2
AO - Angola 2
BG - Bulgaria 2
BY - Bielorussia 2
DZ - Algeria 2
ET - Etiopia 2
KZ - Kazakistan 2
LB - Libano 2
LY - Libia 2
MD - Moldavia 2
MK - Macedonia 2
QA - Qatar 2
RS - Serbia 2
UY - Uruguay 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
BB - Barbados 1
BF - Burkina Faso 1
BH - Bahrain 1
CG - Congo 1
CY - Cipro 1
EE - Estonia 1
GE - Georgia 1
HN - Honduras 1
KG - Kirghizistan 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
ME - Montenegro 1
MN - Mongolia 1
Totale 25.042
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Città #
Dallas 14.756
Southend 699
Dublin 554
Chandler 304
Singapore 300
Fairfield 295
Ashburn 269
Santa Clara 257
Jacksonville 236
Hong Kong 223
Moscow 195
Beijing 185
Woodbridge 161
San Jose 140
Wilmington 134
Siena 115
Seattle 112
Cambridge 108
Houston 107
Princeton 107
Ann Arbor 99
Hefei 93
Menlo Park 87
Nanjing 85
Seoul 85
The Dalles 71
Ho Chi Minh City 56
Boardman 55
Council Bluffs 55
Helsinki 55
Fremont 54
Los Angeles 54
New York 54
Lauterbourg 53
Milan 47
Hanoi 43
Buffalo 38
Johannesburg 37
Munich 36
San Diego 36
San Mateo 36
Shanghai 35
Sesto Fiorentino 33
Florence 30
Nanchang 27
London 26
São Paulo 23
Columbus 22
Orem 22
Dong Ket 21
Brussels 19
Bengaluru 18
Kensington 18
Changsha 17
Shenyang 17
Venezia 17
Chicago 16
Denver 16
Redondo Beach 16
Warsaw 16
Kunming 15
Lancaster 15
Poplar 15
Rome 15
Tianjin 15
Rio de Janeiro 14
San Francisco 14
Zhengzhou 14
Amsterdam 13
Guangzhou 13
Jiaxing 13
Tokyo 13
Abidjan 12
Brno 12
Düsseldorf 12
Jinan 12
Nuremberg 12
Hangzhou 11
Brooklyn 10
Frankfurt am Main 10
Haiphong 10
Brescia 9
Norwalk 9
Prato 9
Tashkent 9
Amman 8
Chennai 8
Da Nang 8
Hebei 8
Vienna 8
West Jordan 8
Bari 7
Dearborn 7
Jakarta 7
Montreal 7
Ningbo 7
Olomouc 7
Toronto 7
Abuja 6
Belo Horizonte 6
Totale 21.310
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Nome #
1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors 7.464
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity 7.357
VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- And metallo-β-lactamases, restores activity of cefepime in enterobacterales and Pseudomonas aeruginosa 351
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease 284
Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem 270
Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam 259
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors 253
Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam. 249
Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design 243
A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases 243
X-ray Crystal Structure of the Acinetobacter baumannii OXA-24/40 Class D Carbapenemase Inhibited by NXL104 223
Crystal structure of AphA class B acid phosphatase/phosphotransferase from E. coli 221
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model 221
Discovery of ANT3310, a novel broad-spectrum serine β-Lactamase inhibitor of the diazabicyclooctane class, which strongly potentiates meropenem activity against carbapenem-resistant enterobacterales and acinetobacter baumannii 220
ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-Producing enterobacteriaceae 216
Crystallization and preliminary crystallographic analysis of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E: a novel dioxygenase involved in the biodegradation of polychlorinated aromatic compounds 213
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates 211
Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases 208
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- And Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections 207
XAS of dilute biological samples 203
Adsorption of metal ions from sulphuric acid solution by chelating resins 199
The structure of the human glutaminyl cyclase–SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders 198
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. Evidence for a dinuclear zinc site 197
Crystal structure and mutational analysis of FUS-1 (OXA-85), a class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum 195
Sulfated hyaluronic acid as heparin-like material: physicochemical and biological characterization 193
Structural characterisation of a new heparinisable material based on ethylene/vinyl alcohol/vinyl acetate terpolymer and a poly(amido-amine) 193
Crystallization of soluble proteins in vapor diffusion for x-ray crystallography 184
Crystal structure of Enterococcus faecalis Thymidylate synthase 184
The first structure of a bacterial class B acid phosphatase reveals further structural heterogeneity among phosphatases of the haloacid dehalogenase fold 183
Acid-base properties and complexing abilities of an aminodicarboxylic acid and its corresponding polymer 179
Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC  beta-Lactamases 173
The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction 171
The soluble Y115E-Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease 171
Sulfated hyaluronic acid as heparin-like material: physico-chemical and biological characterization 164
Structural and functional characterization of two new class D beta-lactamase: OXA-46 and OXA-48 164
High-Resolution Crystal Structure of the Subclass B3 Metallo-beta-Lactamase BJP-1: Rational Basis for Substrate Specificity and Interaction with Sulfonamides 160
Structure of the extended-spectrum beta-lactamase TEM-72 inhibited by citrate 158
Structural Insights into the Catalytic Mechanism of the Bacterial Class B Phosphatase AphA Belonging to the DDDD Superfamily of Phosphohydrolases 158
From an inactive prokaryotic SOD homologue to an active protein through site-directed mutagenesis 158
Structural and functional characterization of two new class D beta-lactamases: OXA-46 and OXA-48 150
Evolution to carbapenem-hydrolyzing activity in class D β-lactamases by rational protein design 150
Evolution to carbapenem -hydrolyzing activity in noncarbapenemase class D beta-lactamase OXA-10 by rational protein design 149
Preparation, physico-chemical and biological characterization of heparinizable materials 145
Metallo-enzyme mechanism from accurate structural data 141
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates 140
Derivati solfatati dell'acido ialuronico come prodotto eparino-simili: caratterizzazione chimico-fisica e biologica 136
New trends in blood compatible materials 131
Calorimetric study of macromolecular complex formation between heparin and poly(amido-amine)s. 127
Expression, purification, crystallization and preliminary X-ray characterization of the class B acid phosphatase (AphA) from Escherichia coli 122
Materials containing heparin complexing polymers, physicochemical characterization and compatibility 122
Derivati solfatati dell'acido ialuronico come prodotti eparino-simili: caratterizzazione chimico-fisica e biologica 121
null 120
Crystallographic studies of new human Thymidylate synthase inhibitors. 112
Synthesis of two novel heparinizable polymeric materials (EVAPA-45 and EVAPA) for hemodialysis membranes 111
Crystallographic studies of new human Thymidylate synthase inhibitors 111
Crystallographic studies of new human Thymidylate synthase inhibitors 110
Synthesis of two novel heparinizable polymeric materials starting from an ethylene/vinyl alcohol/vinyl acetate terpolymer 106
New macromolecular ligands. Basicity and complexing properties of monomeric and polymeric dicarboxylic aminoacids 102
Synthesis and chemical characterization: characterization of biomaterials in contact with blood 99
Large size chelate rings in copper(II) complexes with triamine 97
null 54
Totale 25.154
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Categoria #
all - tutte 47.792
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.792
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202183 0 0 0 0 0 0 0 0 0 0 0 83
2021/2022758 38 97 68 49 77 27 32 39 26 76 62 167
2022/20231.069 69 77 126 135 115 236 17 103 128 12 27 24
2023/2024898 42 16 60 34 52 205 290 24 2 30 29 114
2024/20251.781 96 104 132 111 267 105 87 116 105 67 167 424
2025/202617.589 294 4.052 10.940 577 670 142 359 104 158 180 75 38
Totale 25.154