A partially hydrolyzed ethylene/vinyl acetate (EVA) copolymer was modified through the covalent binding of a heparin-complexing polymer, in order to improve its blood compatibility. Two different heparinizable polymeric materials (EVAPA I and II) were obtained by a two-step reaction between an ethylene/vinyl alcohol/vinyl acetate (EVALVA) terpolymer and a poly-(amido-amine) (N2LL) using either hexamethylene diisocyanate (HMDI) or 1,1'-carbonyldimidazole (CDI) as bifunctional agents. EVALVA terpolymer was prepared by a homogeneous saponification process, and the percentage of hydrolysis was determined by an analytical method. EVAPA I and II syntheses were followed by FT-IR/ATR (Fourier Transform Infrared/Attenuated Total Reflection) spectroscopy.
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|Titolo:||Synthesis of two novel heparinizable polymeric materials starting from an ethylene/vinyl alcohol/vinyl acetate terpolymer|
|Citazione:||R., B., Benvenuti, M., Magnani, A., & F., T. (1992). Synthesis of two novel heparinizable polymeric materials starting from an ethylene/vinyl alcohol/vinyl acetate terpolymer. DIE MAKROMOLEKULARE CHEMIE, 193(12), 2979-2988.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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