BENVENUTI, MANUELA
BENVENUTI, MANUELA
Dipartimento di Biotecnologie, Chimica e Farmacia
1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors
2022-01-01 Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity
2021-01-01 Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors
2020-01-01 Gavara, L.; Sevaille, L.; De Luca, F.; Mercuri, P.; Bebrone, C.; Feller, G.; Legru, A.; Cerboni, G.; Tanfoni, S.; Baud, D.; Cutolo, G.; Bestgen, B.; Chelini, G.; Verdirosa, F.; Sannio, F.; Pozzi, C.; Benvenuti, M.; Kwapien, K.; Fischer, M.; Becker, K.; Frere, J. -M.; Mangani, S.; Gresh, N.; Berthomieu, D.; Galleni, M.; Docquier, Jd; Hernandez, J. -F.
A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases
2006-01-01 Calderone, V.; Forleo, C.; Benvenuti, Manuela; Thaller, M. C.; Rossolini, G. M.; Mangani, Stefano
Acid-base properties and complexing abilities of an aminodicarboxylic acid and its corresponding polymer
1986-01-01 Benvenuti, M.; Casolaro, Mario; Fini, A.; Laus, M.
Adsorption of metal ions from sulphuric acid solution by chelating resins
1984-01-01 Benvenuti, M.; Billi, A.; Casolaro, Mario
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease
2018-01-01 Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Benvenuti, Manuela; Costi, MARIA PAOLA; Mangani, Stefano
ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-Producing enterobacteriaceae
2020-01-01 Davies, D. T.; Leiris, S.; Sprynski, N.; Castandet, J.; Lozano, C.; Bousquet, J.; Zalacain, M.; Vasa, S.; Dasari, P. K.; Pattipati, R.; Vempala, N.; Gujjewar, S.; Godi, S.; Jallala, R.; Sathyap, R. R.; Darshanoju, N. A.; Ravu, V. R.; Juventhala, R. R.; Pottabathini, N.; Sharma, S.; Pothukanuri, S.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Mangani, S.; Docquier, J. D.; Lemonnier, M.; Everett, M.
Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam
2018-01-01 Pozzi, Cecilia; Di Pisa, Flavio; De Luca, Filomena; Benvenuti, Manuela; Docquier, Jean Denis; Mangani, Stefano
Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design
2018-01-01 Di Pisa, Flavio; Pozzi, Cecilia; Benvenuti, Manuela; Docquier, Jean-Denis; De Luca, Filomena; Mangani, Stefano
Calorimetric study of macromolecular complex formation between heparin and poly(amido-amine)s.
1983-01-01 Benvenuti, M.; Casini, G.; Casolaro, Mario; Ghedini, N.; Tempesti, E.
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. Evidence for a dinuclear zinc site
2007-01-01 Mangani, Stefano; Benvenuti, Manuela; Moir, A. J.; Ranieri Raggi, M.; Martini, D.; Sabbatini, A. R.; Raggi, A.
Crystal structure and mutational analysis of FUS-1 (OXA-85), a class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum
2006-01-01 Benvenuti, M.; Calderone, V.; Docquier, JEAN DENIS; Fosse, T.; Mangani, Stefano; Rossolini, GIAN MARIA; Voha, C.
Crystal structure of AphA class B acid phosphatase/phosphotransferase from E. coli
2003-01-01 Calderone, Vito; C., Forleo; Benvenuti, Manuela; Rossolini, GIAN MARIA; Mangani, Stefano; M. C., Thaller
Crystal structure of Enterococcus faecalis Thymidylate synthase
2010-01-01 Pozzi, Cecilia; Benvenuti, Manuela; Ferrari, Stefania; Luciani, Rosaria; Catalano, Alessia; Stroud Robert, M.; Costi Maria, Paola; Mangani, Stefano
Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam.
2013-01-01 Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, L.; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS
Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates
2010-01-01 Docquier, JEAN DENIS; Benvenuti, Manuela; Calderone, V; Giuliani, F; Kapetis, D; DE LUCA, Filomena; Rossolini, GIAN MARIA; Mangani, Stefano
Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases
2009-01-01 Docquier, J. D.; Calderone, V.; De Luca, F.; Benvenuti, M.; Giuliani, F.; Bellucci, L.; Tafi, A.; Nordmann, P.; Botta, M.; Rossolini, G. M.; Mangani, S.
Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem
2016-01-01 Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, Laurent; Nordmann, Patrice; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS
Crystallization and preliminary crystallographic analysis of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E: a novel dioxygenase involved in the biodegradation of polychlorinated aromatic compounds
1999-01-01 Benvenuti, Manuela; F., Briganti; A., Scozzafava; L., Golovleva; V. M., Travkin; Mangani, Stefano
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors | 1-gen-2022 | Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François | - | |
| 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity | 1-gen-2021 | Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent | - | |
| 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors | 1-gen-2020 | Gavara, L.; Sevaille, L.; De Luca, F.; Mercuri, P.; Bebrone, C.; Feller, G.; Legru, A.; Cerboni, G.; Tanfoni, S.; Baud, D.; Cutolo, G.; Bestgen, B.; Chelini, G.; Verdirosa, F.; Sannio, F.; Pozzi, C.; Benvenuti, M.; Kwapien, K.; Fischer, M.; Becker, K.; Frere, J. -M.; Mangani, S.; Gresh, N.; Berthomieu, D.; Galleni, M.; Docquier, Jd; Hernandez, J. -F. | - | |
| A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases | 1-gen-2006 | Calderone, V.; Forleo, C.; Benvenuti, Manuela; Thaller, M. C.; Rossolini, G. M.; Mangani, Stefano | - | |
| Acid-base properties and complexing abilities of an aminodicarboxylic acid and its corresponding polymer | 1-gen-1986 | Benvenuti, M.; Casolaro, Mario; Fini, A.; Laus, M. | - | |
| Adsorption of metal ions from sulphuric acid solution by chelating resins | 1-gen-1984 | Benvenuti, M.; Billi, A.; Casolaro, Mario | - | |
| Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease | 1-gen-2018 | Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Benvenuti, Manuela; Costi, MARIA PAOLA; Mangani, Stefano | - | |
| ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-Producing enterobacteriaceae | 1-gen-2020 | Davies, D. T.; Leiris, S.; Sprynski, N.; Castandet, J.; Lozano, C.; Bousquet, J.; Zalacain, M.; Vasa, S.; Dasari, P. K.; Pattipati, R.; Vempala, N.; Gujjewar, S.; Godi, S.; Jallala, R.; Sathyap, R. R.; Darshanoju, N. A.; Ravu, V. R.; Juventhala, R. R.; Pottabathini, N.; Sharma, S.; Pothukanuri, S.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Mangani, S.; Docquier, J. D.; Lemonnier, M.; Everett, M. | - | |
| Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam | 1-gen-2018 | Pozzi, Cecilia; Di Pisa, Flavio; De Luca, Filomena; Benvenuti, Manuela; Docquier, Jean Denis; Mangani, Stefano | - | |
| Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design | 1-gen-2018 | Di Pisa, Flavio; Pozzi, Cecilia; Benvenuti, Manuela; Docquier, Jean-Denis; De Luca, Filomena; Mangani, Stefano | - | |
| Calorimetric study of macromolecular complex formation between heparin and poly(amido-amine)s. | 1-gen-1983 | Benvenuti, M.; Casini, G.; Casolaro, Mario; Ghedini, N.; Tempesti, E. | - | |
| Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. Evidence for a dinuclear zinc site | 1-gen-2007 | Mangani, Stefano; Benvenuti, Manuela; Moir, A. J.; Ranieri Raggi, M.; Martini, D.; Sabbatini, A. R.; Raggi, A. | - | |
| Crystal structure and mutational analysis of FUS-1 (OXA-85), a class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum | 1-gen-2006 | Benvenuti, M.; Calderone, V.; Docquier, JEAN DENIS; Fosse, T.; Mangani, Stefano; Rossolini, GIAN MARIA; Voha, C. | - | |
| Crystal structure of AphA class B acid phosphatase/phosphotransferase from E. coli | 1-gen-2003 | Calderone, Vito; C., Forleo; Benvenuti, Manuela; Rossolini, GIAN MARIA; Mangani, Stefano; M. C., Thaller | - | |
| Crystal structure of Enterococcus faecalis Thymidylate synthase | 1-gen-2010 | Pozzi, Cecilia; Benvenuti, Manuela; Ferrari, Stefania; Luciani, Rosaria; Catalano, Alessia; Stroud Robert, M.; Costi Maria, Paola; Mangani, Stefano | - | |
| Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam. | 1-gen-2013 | Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, L.; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS | - | |
| Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates | 1-gen-2010 | Docquier, JEAN DENIS; Benvenuti, Manuela; Calderone, V; Giuliani, F; Kapetis, D; DE LUCA, Filomena; Rossolini, GIAN MARIA; Mangani, Stefano | - | |
| Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases | 1-gen-2009 | Docquier, J. D.; Calderone, V.; De Luca, F.; Benvenuti, M.; Giuliani, F.; Bellucci, L.; Tafi, A.; Nordmann, P.; Botta, M.; Rossolini, G. M.; Mangani, S. | - | |
| Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem | 1-gen-2016 | Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, Laurent; Nordmann, Patrice; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS | - | |
| Crystallization and preliminary crystallographic analysis of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E: a novel dioxygenase involved in the biodegradation of polychlorinated aromatic compounds | 1-gen-1999 | Benvenuti, Manuela; F., Briganti; A., Scozzafava; L., Golovleva; V. M., Travkin; Mangani, Stefano | - |