GIANNINI, ALESSIA
GIANNINI, ALESSIA
Dipartimento di Scienze Mediche, Chirurgiche e Neuroscienze
(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity
2020-01-01 Humbert, N; Kovalenko, L; Saladini, F; Giannini, A; Pires, M; Botzanowski, T; Cherenok, S; Boudier, C; Sharma, Kk; Real, E; Zaporozhets, Oa; Cianférani, S; Seguin-Devaux, C; Poggialini, F; Botta, M; Zazzi, M; Kalchenko, Vi; Mori, M; Mély, Y.
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein
2020-01-01 Malancona, Savina; Mori, Mattia; Fezzardi, Paola; Santoriello, Marisabella; Basta, Andreina; Nibbio, Martina; Kovalenko, Lesia; Speziale, Roberto; Battista, Maria Rosaria; Cellucci, Antonella; Gennari, Nadia; Monteagudo, Edith; Di Marco, Annalise; Giannini, Alessia; Sharma, Rajhans; Pires, Manuel; Real, Eleonore; Zazzi, Maurizio; Dasso Lang, Maria Chiara; De Forni, Davide; Saladini, Francesco; Mely, Yves; Summa, Vincenzo; Harper, Steven; Botta, Maurizio
Agreement between an in-house replication competent and a reference replication defective recombinant virus assay for measuring phenotypic resistance to HIV-1 protease, reverse transcriptase, and integrase inhibitors
2018-01-01 Saladini, Francesco; Giannini, Alessia; Boccuto, Adele; Vicenti, Ilaria; Zazzi, Maurizio
Comparable in vitro activity of second-generation HIV-1 integrase strand transfer inhibitors (INSTIs) on HIV-1 clinical isolates with INSTI resistance mutations
2020-01-01 Saladini, Francesco; Giannini, Alessia; Boccuto, Adele; Dragoni, Filippo; Appendino, Alice; Albanesi, Edoardo; Vicenti, Ilaria; Zazzi, Maurizio
Comparative analysis of different cell systems for Zika virus (ZIKV) propagation and evaluation of anti-ZIKV compounds in vitro
2018-01-01 Vicenti, Ilaria; Boccuto, Adele; Giannini, Alessia; Dragoni, Filippo; Saladini, Francesco; Zazzi, Maurizio
DDX3X inhibitors, an effective way to overcome HIV-1 resistance
2020-01-01 Brai, Annalaura; Riva, Valentina; Saladini, Francesco; Zamperini, Claudio; Trivisani, Claudia; Garbelli, Anna; Pennisi, Carla; Giannini, Alessia; Boccuto, Adele; Bugli, Francesca; Martini, Maurizio; Sanguinetti, Maurizio; Dreassi, Elena; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio
Development of a Cell-Based Immunodetection Assay for Simultaneous Screening of Antiviral Compounds Inhibiting Zika and Dengue Virus Replication.
2020-01-01 Vicenti, I; Dragoni, F; Giannini, A; Giammarino, F; Spinicci, M; Saladini, F; Boccuto, A; Zazzi, M.
Development of an internally controlled quantitative PCR to measure total cell-associated HIV-1 DNA in blood
2018-01-01 Vicenti, Ilaria; Meini, Genny; Saladini, Francesco; Giannini, Alessia; Boccuto, Adele; Schiaroli, Elisabetta; Zazzi, Maurizio
Evaluation of sofosbuvir activity and resistance profile against West Nile virus in vitro
2020-01-01 Dragoni, F; Boccuto, A; Picarazzi, F; Giannini, A; Giammarino, F; Saladini, F; Mori, M; Mastrangelo, E; Zazzi, M; Vicenti, I.
External quality assessment of HIV-1 DNA quantification assays used in the clinical setting in Italy
2022-01-01 Vicenti, Ilaria; Dragoni, Filippo; Giannini, Alessia; Casabianca, Anna; Lombardi, Francesca; Di Sante, Laura; Turriziani, Ombretta; Racca, Sara; Paolucci, Stefania; Lai, Alessia; Bon, Isabella; Abbate, Isabella; Rozera, Gabriella; Belmonti, Simone; Scutari, Rossana; Alteri, Claudia; Saladini, Francesco; Zazzi, Maurizio
HIV drug discovery and resistance testing through cell based assays
2019-01-01 Giannini, Alessia
Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein
2018-01-01 Gamba, Elia; Mori, Mattia; Kovalenko, Lesia; Giannini, Alessia; Sosic, Alice; Saladini, Francesco; Fabris, Dan; Mély, Yves; Gatto, Barbara; Botta, Maurizio
In vitro cross-resistance to doravirine in a panel of HIV-1 clones harbouring multiple NNRTI resistance mutations
2021-01-01 Saladini, F.; Giammarino, F.; Hosseini, B. A.; Giannini, A.; Boccuto, A.; Dragoni, F.; Vicenti, I.; Shafer, R. W.; Zazzi, M.
In vitro susceptibility of HIV-1 CRF02_AG to temsavir, the active compound of the attachment inhibitor fostemsavir
2021-01-01 Saladini, Francesco; Giannini, Alessia; Giammarino, Federica; Boccuto, Adele; Dragoni, Filippo; Vicenti, Ilaria; Zazzi, Maurizio
In vitro susceptibility to fostemsavir is not affected by long-term exposure to antiviral therapy in MDR HIV-1-infected patients
2020-01-01 Saladini, Francesco; Giannini, Alessia; Giammarino, Federica; Maggiolo, Franco; Vichi, Francesca; Corbelli, Giulio M; Galli, Andrea; Bigoloni, Alba; Poli, Andrea; Santoro, Maria M; Zazzi, Maurizio; Castagna, Antonella
Maraviroc as a potential HIV-1 latency-reversing agent in cell line models and ex vivo CD4 T cells
2021-01-01 Vicenti, Ilaria; Dragoni, Filippo; Monti, Martina; Trombetta, Claudia Maria; Giannini, Alessia; Boccuto, Adele; Saladini, Francesco; Rossetti, Barbara; De Luca, Andrea; Ciabattini, Annalisa; Pastore, Gabiria; Medaglini, Donata; Orofino, Giancarlo; Montomoli, Emanuele; Zazzi, Maurizio
Performance of Geno2Pheno[coreceptor] to infer coreceptor use in human immunodeficiency virus type 1 (HIV-1) subtype A
2019-01-01 Vicenti, I.; Lai, A.; Giannini, A.; Boccuto, A.; Dragoni, F.; Saladini, F.; Zazzi, M.
Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains
2018-01-01 Mori, Mattia; Kovalenko, Lesia; Malancona, Savina; Saladini, Francesco; De Forni, Davide; Pires, Manuel; Humbert, Nicolas; Real, Eleonore; Botzanowski, Thomas; Cianférani, Sarah; Giannini, Alessia; Dasso Lang, Maria Chiara; Cugia, Giulia; Poddesu, Barbara; Lori, Franco; Zazzi, Maurizio; Harper, Steven; Summa, Vincenzo; Mely, Yves; Botta, Maurizio
Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein
2019-01-01 Mori, M.; Dasso Lang, M. C.; Saladini, F.; Palombi, N.; Kovalenko, L.; De Forni, D.; Poddesu, B.; Friggeri, L.; Giannini, A.; Malancona, S.; Summa, V.; Zazzi, M.; Mely, Y.; Botta, M.
The HIV-1 integrase E157Q polymorphism per se does not alter susceptibility to raltegravir and dolutegravir in vitro
2017-01-01 Saladini, Francesco; Giannini, Alessia; Boccuto, Adele; Tiezzi, Diletta; Vicenti, Ilaria; Zazzi, Maurizio
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| (Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity | 1-gen-2020 | Humbert, N; Kovalenko, L; Saladini, F; Giannini, A; Pires, M; Botzanowski, T; Cherenok, S; Boudier, C; Sharma, Kk; Real, E; Zaporozhets, Oa; Cianférani, S; Seguin-Devaux, C; Poggialini, F; Botta, M; Zazzi, M; Kalchenko, Vi; Mori, M; Mély, Y. | - | |
| 5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein | 1-gen-2020 | Malancona, Savina; Mori, Mattia; Fezzardi, Paola; Santoriello, Marisabella; Basta, Andreina; Nibbio, Martina; Kovalenko, Lesia; Speziale, Roberto; Battista, Maria Rosaria; Cellucci, Antonella; Gennari, Nadia; Monteagudo, Edith; Di Marco, Annalise; Giannini, Alessia; Sharma, Rajhans; Pires, Manuel; Real, Eleonore; Zazzi, Maurizio; Dasso Lang, Maria Chiara; De Forni, Davide; Saladini, Francesco; Mely, Yves; Summa, Vincenzo; Harper, Steven; Botta, Maurizio | - | |
| Agreement between an in-house replication competent and a reference replication defective recombinant virus assay for measuring phenotypic resistance to HIV-1 protease, reverse transcriptase, and integrase inhibitors | 1-gen-2018 | Saladini, Francesco; Giannini, Alessia; Boccuto, Adele; Vicenti, Ilaria; Zazzi, Maurizio | - | |
| Comparable in vitro activity of second-generation HIV-1 integrase strand transfer inhibitors (INSTIs) on HIV-1 clinical isolates with INSTI resistance mutations | 1-gen-2020 | Saladini, Francesco; Giannini, Alessia; Boccuto, Adele; Dragoni, Filippo; Appendino, Alice; Albanesi, Edoardo; Vicenti, Ilaria; Zazzi, Maurizio | - | |
| Comparative analysis of different cell systems for Zika virus (ZIKV) propagation and evaluation of anti-ZIKV compounds in vitro | 1-gen-2018 | Vicenti, Ilaria; Boccuto, Adele; Giannini, Alessia; Dragoni, Filippo; Saladini, Francesco; Zazzi, Maurizio | - | |
| DDX3X inhibitors, an effective way to overcome HIV-1 resistance | 1-gen-2020 | Brai, Annalaura; Riva, Valentina; Saladini, Francesco; Zamperini, Claudio; Trivisani, Claudia; Garbelli, Anna; Pennisi, Carla; Giannini, Alessia; Boccuto, Adele; Bugli, Francesca; Martini, Maurizio; Sanguinetti, Maurizio; Dreassi, Elena; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio | - | |
| Development of a Cell-Based Immunodetection Assay for Simultaneous Screening of Antiviral Compounds Inhibiting Zika and Dengue Virus Replication. | 1-gen-2020 | Vicenti, I; Dragoni, F; Giannini, A; Giammarino, F; Spinicci, M; Saladini, F; Boccuto, A; Zazzi, M. | - | |
| Development of an internally controlled quantitative PCR to measure total cell-associated HIV-1 DNA in blood | 1-gen-2018 | Vicenti, Ilaria; Meini, Genny; Saladini, Francesco; Giannini, Alessia; Boccuto, Adele; Schiaroli, Elisabetta; Zazzi, Maurizio | - | |
| Evaluation of sofosbuvir activity and resistance profile against West Nile virus in vitro | 1-gen-2020 | Dragoni, F; Boccuto, A; Picarazzi, F; Giannini, A; Giammarino, F; Saladini, F; Mori, M; Mastrangelo, E; Zazzi, M; Vicenti, I. | - | |
| External quality assessment of HIV-1 DNA quantification assays used in the clinical setting in Italy | 1-gen-2022 | Vicenti, Ilaria; Dragoni, Filippo; Giannini, Alessia; Casabianca, Anna; Lombardi, Francesca; Di Sante, Laura; Turriziani, Ombretta; Racca, Sara; Paolucci, Stefania; Lai, Alessia; Bon, Isabella; Abbate, Isabella; Rozera, Gabriella; Belmonti, Simone; Scutari, Rossana; Alteri, Claudia; Saladini, Francesco; Zazzi, Maurizio | - | |
| HIV drug discovery and resistance testing through cell based assays | 1-gen-2019 | Giannini, Alessia | - | |
| Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein | 1-gen-2018 | Gamba, Elia; Mori, Mattia; Kovalenko, Lesia; Giannini, Alessia; Sosic, Alice; Saladini, Francesco; Fabris, Dan; Mély, Yves; Gatto, Barbara; Botta, Maurizio | - | |
| In vitro cross-resistance to doravirine in a panel of HIV-1 clones harbouring multiple NNRTI resistance mutations | 1-gen-2021 | Saladini, F.; Giammarino, F.; Hosseini, B. A.; Giannini, A.; Boccuto, A.; Dragoni, F.; Vicenti, I.; Shafer, R. W.; Zazzi, M. | - | |
| In vitro susceptibility of HIV-1 CRF02_AG to temsavir, the active compound of the attachment inhibitor fostemsavir | 1-gen-2021 | Saladini, Francesco; Giannini, Alessia; Giammarino, Federica; Boccuto, Adele; Dragoni, Filippo; Vicenti, Ilaria; Zazzi, Maurizio | - | |
| In vitro susceptibility to fostemsavir is not affected by long-term exposure to antiviral therapy in MDR HIV-1-infected patients | 1-gen-2020 | Saladini, Francesco; Giannini, Alessia; Giammarino, Federica; Maggiolo, Franco; Vichi, Francesca; Corbelli, Giulio M; Galli, Andrea; Bigoloni, Alba; Poli, Andrea; Santoro, Maria M; Zazzi, Maurizio; Castagna, Antonella | - | |
| Maraviroc as a potential HIV-1 latency-reversing agent in cell line models and ex vivo CD4 T cells | 1-gen-2021 | Vicenti, Ilaria; Dragoni, Filippo; Monti, Martina; Trombetta, Claudia Maria; Giannini, Alessia; Boccuto, Adele; Saladini, Francesco; Rossetti, Barbara; De Luca, Andrea; Ciabattini, Annalisa; Pastore, Gabiria; Medaglini, Donata; Orofino, Giancarlo; Montomoli, Emanuele; Zazzi, Maurizio | - | |
| Performance of Geno2Pheno[coreceptor] to infer coreceptor use in human immunodeficiency virus type 1 (HIV-1) subtype A | 1-gen-2019 | Vicenti, I.; Lai, A.; Giannini, A.; Boccuto, A.; Dragoni, F.; Saladini, F.; Zazzi, M. | - | |
| Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains | 1-gen-2018 | Mori, Mattia; Kovalenko, Lesia; Malancona, Savina; Saladini, Francesco; De Forni, Davide; Pires, Manuel; Humbert, Nicolas; Real, Eleonore; Botzanowski, Thomas; Cianférani, Sarah; Giannini, Alessia; Dasso Lang, Maria Chiara; Cugia, Giulia; Poddesu, Barbara; Lori, Franco; Zazzi, Maurizio; Harper, Steven; Summa, Vincenzo; Mely, Yves; Botta, Maurizio | - | |
| Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein | 1-gen-2019 | Mori, M.; Dasso Lang, M. C.; Saladini, F.; Palombi, N.; Kovalenko, L.; De Forni, D.; Poddesu, B.; Friggeri, L.; Giannini, A.; Malancona, S.; Summa, V.; Zazzi, M.; Mely, Y.; Botta, M. | - | |
| The HIV-1 integrase E157Q polymorphism per se does not alter susceptibility to raltegravir and dolutegravir in vitro | 1-gen-2017 | Saladini, Francesco; Giannini, Alessia; Boccuto, Adele; Tiezzi, Diletta; Vicenti, Ilaria; Zazzi, Maurizio | - |