DOCQUIER, JEAN DENIS
DOCQUIER, JEAN DENIS
Dipartimento di Biotecnologie Mediche
1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors
2022-01-01 Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François
1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors
2022-01-01 Gavara, Laurent; Verdirosa, Federica; Sevaille, Laurent; Legru, Alice; Corsica, Giuseppina; Nauton, Lionel; Sandra Mercuri, Paola; Sannio, Filomena; De Luca, Filomena; Hadjadj, Margot; Cerboni, Giulia; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Docquier, Jean-Denis; Hernandez, Jean-François
1,2,4-Triazole-3-thione compounds as inhibitors of di-zinc metallo-β-lactamases
2017-01-01 Sevaille, Laurent; Gavara, Laurent; Bebrone, Carine; DE LUCA, Filomena; Nauton, Lionel; Achard, Maud; Mercuri, Paola; Tanfoni, Silvia; Borgianni, Luisa; Guyon, Carole; Lonjon, Pauline; Turan Zitouni, Gülhan; Dzieciolowski, Julia; Becker, Katja; Bénard, Lionel; Condon, Ciaran; Maillard, Ludovic; Martinez, Jean; Frère, Jean Marie; Dideberg, Otto; Galleni, Moreno; Docquier, JEAN DENIS; Hernandez, Jean François
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity
2021-01-01 Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent
4-(N-alkyl-and-acyl-amino)-1,2,4-triazole-3-thione analogs as metallo-β-lactamase inhibitors: Impact of 4-linker on potency and spectrum of inhibition
2020-01-01 Gavara, L.; Verdirosa, F.; Legru, A.; Mercuri, P. S.; Nauton, L.; Sevaille, L.; Feller, G.; Berthomieu, D.; Sannio, F.; Marcoccia, F.; Tanfoni, S.; Luca, F. D.; Gresh, N.; Galleni, M.; Docquier, J. D.; Hernandez, J. -F.
4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors
2021-01-01 Gavara, Laurent; Legru, Alice; Verdirosa, Federica; Sevaille, Laurent; Nauton, Lionel; Corsica, Giuseppina; Mercuri, Paola Sandra; Sannio, Filomena; Feller, Georges; Coulon, Rémi; De Luca, Filomena; Cerboni, Giulia; Tanfoni, Silvia; Chelini, Giulia; Galleni, Moreno; Docquier, Jean-Denis; Hernandez, Jean-François
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors
2020-01-01 Gavara, L.; Sevaille, L.; De Luca, F.; Mercuri, P.; Bebrone, C.; Feller, G.; Legru, A.; Cerboni, G.; Tanfoni, S.; Baud, D.; Cutolo, G.; Bestgen, B.; Chelini, G.; Verdirosa, F.; Sannio, F.; Pozzi, C.; Benvenuti, M.; Kwapien, K.; Fischer, M.; Becker, K.; Frere, J. -M.; Mangani, S.; Gresh, N.; Berthomieu, D.; Galleni, M.; Docquier, Jd; Hernandez, J. -F.
4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections
2024-01-01 Barbieri, Francesca; Carlen, Vincent; Martina, Maria Grazia; Sannio, Filomena; Cancade, Sacha; Perini, Cecilia; Restori, Margherita; Crespan, Emmanuele; Maga, Giovanni; Docquier, Jean-Denis; Cagno, Valeria; Radi, Marco
[Carbapenem resistance in Pseudomonas aeruginosa isolates: an example of interaction between different mechanisms].
2011-01-01 Santella, G; Pollini, Simona; Docquier, JEAN DENIS; Almuzara, M; Gutkind, G; Rossolini, GIAN MARIA; Radice, M.
A Clinical Study Provides the First Direct Evidence That Interindividual Variations in Fecal β-Lactamase Activity Affect the Gut Mycobiota Dynamics in Response to β-Lactam Antibiotics
2022-01-01 Delavy, Margot; Burdet, Charles; Sertour, Natacha; Devente, Savannah; Docquier, Jean-Denis; Grall, Nathalie; Volant, Stevenn; Ghozlane, Amine; Duval, Xavier; Mentré, France; D'Enfert, Christophe; Bougnoux, Marie-Elisabeth
A fragment-based drug discovery strategy applied to the identification of NDM-1 β-lactamase inhibitors
2022-01-01 Caburet, Jérémy; Boucherle, Benjamin; Bourdillon, Sofiane; Simoncelli, Giorgia; Verdirosa, Federica; Docquier, Jean-Denis; Moreau, Yohann; Krimm, Isabelle; Crouzy, Serge; Peuchmaur, Marine
A standard numbering scheme for class C β-lactamases
2020-01-01 Mack, A. R.; Barnes, M. D.; Taracila, M. A.; Hujer, A. M.; Hujer, K. M.; Cabot, G.; Feldgarden, M.; Haft, D. H.; Klimke, W.; Van Den Akker, F.; Vila, A. J.; Smania, A.; Haider, S.; Papp-Wallace, K. M.; Bradford, P. A.; Rossolini, G. M.; Docquier, J. D.; Frere, J. -M.; Galleni, M.; Hanson, N. D.; Oliver, A.; Plesiat, P.; Poirel, L.; Nordmann, P.; Palzkill, T. G.; Jacoby, G. A.; Bush, K.; Bonomo, R. A.
Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization
2018-01-01 Pasero, Carolina; D'Agostino, Ilaria; De Luca, Filomena; Zamperini, Claudio; Deodato, Davide; Truglio, Giuseppina I.; Sannio, Filomena; DEL PRETE, Rosita; Ferraro, Teresa; Visaggio, Daniela; Mancini, Arianna; Guglielmi, Mario B.; Visca, Paolo; Docquier, Jean-Denis; Botta, Maurizio
Amino acid replacement at position 228 induces fluctuation in the Ω-loop of KPC-3 and reduces the affinity against oxyimino cephalosporins: Kinetic and molecular dynamics studies
2020-01-01 Piccirilli, A.; Brisdelli, F.; Docquier, J. D.; Aschi, M.; Cherubini, S.; De Luca, F.; Matagne, A.; Amicosante, G.; Perilli, M.
An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library
2024-01-01 Ardino, C.; Sannio, F.; Poli, G.; Galati, S.; Dreassi, E.; Botta, L.; Docquier, J. D.; D'Agostino, I.
An update on β-lactamase inhibitor discovery and development
2018-01-01 Docquier, Jean-Denis; Mangani, Stefano
Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy
2021-01-01 Martin, M. J.; Corey, B. W.; Sannio, F.; Hall, L. R.; Macdonald, U.; Jones, B. T.; Mills, E. G.; Harless, C.; Stam, J.; Maybank, R.; Kwak, Y.; Schaufler, K.; Becker, K.; Hubner, N. -O.; Cresti, S.; Tordini, G.; Valassina, M.; Cusi, M. G.; Bennett, J. W.; Russo, T. A.; Mcgann, P. T.; Lebreton, F.; Docquier, J
ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-Producing enterobacteriaceae
2020-01-01 Davies, D. T.; Leiris, S.; Sprynski, N.; Castandet, J.; Lozano, C.; Bousquet, J.; Zalacain, M.; Vasa, S.; Dasari, P. K.; Pattipati, R.; Vempala, N.; Gujjewar, S.; Godi, S.; Jallala, R.; Sathyap, R. R.; Darshanoju, N. A.; Ravu, V. R.; Juventhala, R. R.; Pottabathini, N.; Sharma, S.; Pothukanuri, S.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Mangani, S.; Docquier, J. D.; Lemonnier, M.; Everett, M.
Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA
2022-01-01 D'Agostino, I.; Ardino, C.; Poli, G.; Sannio, F.; Lucidi, M.; Poggialini, F.; Visaggio, D.; Rango, E.; Filippi, S.; Petricci, E.; Visca, P.; Botta, L.; Docquier, J. -D.; Dreassi, E.
Antibiotic Resistance, Medical Need and Development of Novel Antibacterials
2014-01-01 Docquier, JEAN DENIS
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors | 1-gen-2022 | Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François | - | |
| 1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors | 1-gen-2022 | Gavara, Laurent; Verdirosa, Federica; Sevaille, Laurent; Legru, Alice; Corsica, Giuseppina; Nauton, Lionel; Sandra Mercuri, Paola; Sannio, Filomena; De Luca, Filomena; Hadjadj, Margot; Cerboni, Giulia; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Docquier, Jean-Denis; Hernandez, Jean-François | - | |
| 1,2,4-Triazole-3-thione compounds as inhibitors of di-zinc metallo-β-lactamases | 1-gen-2017 | Sevaille, Laurent; Gavara, Laurent; Bebrone, Carine; DE LUCA, Filomena; Nauton, Lionel; Achard, Maud; Mercuri, Paola; Tanfoni, Silvia; Borgianni, Luisa; Guyon, Carole; Lonjon, Pauline; Turan Zitouni, Gülhan; Dzieciolowski, Julia; Becker, Katja; Bénard, Lionel; Condon, Ciaran; Maillard, Ludovic; Martinez, Jean; Frère, Jean Marie; Dideberg, Otto; Galleni, Moreno; Docquier, JEAN DENIS; Hernandez, Jean François | - | |
| 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity | 1-gen-2021 | Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent | - | |
| 4-(N-alkyl-and-acyl-amino)-1,2,4-triazole-3-thione analogs as metallo-β-lactamase inhibitors: Impact of 4-linker on potency and spectrum of inhibition | 1-gen-2020 | Gavara, L.; Verdirosa, F.; Legru, A.; Mercuri, P. S.; Nauton, L.; Sevaille, L.; Feller, G.; Berthomieu, D.; Sannio, F.; Marcoccia, F.; Tanfoni, S.; Luca, F. D.; Gresh, N.; Galleni, M.; Docquier, J. D.; Hernandez, J. -F. | - | |
| 4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors | 1-gen-2021 | Gavara, Laurent; Legru, Alice; Verdirosa, Federica; Sevaille, Laurent; Nauton, Lionel; Corsica, Giuseppina; Mercuri, Paola Sandra; Sannio, Filomena; Feller, Georges; Coulon, Rémi; De Luca, Filomena; Cerboni, Giulia; Tanfoni, Silvia; Chelini, Giulia; Galleni, Moreno; Docquier, Jean-Denis; Hernandez, Jean-François | - | |
| 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors | 1-gen-2020 | Gavara, L.; Sevaille, L.; De Luca, F.; Mercuri, P.; Bebrone, C.; Feller, G.; Legru, A.; Cerboni, G.; Tanfoni, S.; Baud, D.; Cutolo, G.; Bestgen, B.; Chelini, G.; Verdirosa, F.; Sannio, F.; Pozzi, C.; Benvenuti, M.; Kwapien, K.; Fischer, M.; Becker, K.; Frere, J. -M.; Mangani, S.; Gresh, N.; Berthomieu, D.; Galleni, M.; Docquier, Jd; Hernandez, J. -F. | - | |
| 4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections | 1-gen-2024 | Barbieri, Francesca; Carlen, Vincent; Martina, Maria Grazia; Sannio, Filomena; Cancade, Sacha; Perini, Cecilia; Restori, Margherita; Crespan, Emmanuele; Maga, Giovanni; Docquier, Jean-Denis; Cagno, Valeria; Radi, Marco | - | |
| [Carbapenem resistance in Pseudomonas aeruginosa isolates: an example of interaction between different mechanisms]. | 1-gen-2011 | Santella, G; Pollini, Simona; Docquier, JEAN DENIS; Almuzara, M; Gutkind, G; Rossolini, GIAN MARIA; Radice, M. | - | |
| A Clinical Study Provides the First Direct Evidence That Interindividual Variations in Fecal β-Lactamase Activity Affect the Gut Mycobiota Dynamics in Response to β-Lactam Antibiotics | 1-gen-2022 | Delavy, Margot; Burdet, Charles; Sertour, Natacha; Devente, Savannah; Docquier, Jean-Denis; Grall, Nathalie; Volant, Stevenn; Ghozlane, Amine; Duval, Xavier; Mentré, France; D'Enfert, Christophe; Bougnoux, Marie-Elisabeth | - | |
| A fragment-based drug discovery strategy applied to the identification of NDM-1 β-lactamase inhibitors | 1-gen-2022 | Caburet, Jérémy; Boucherle, Benjamin; Bourdillon, Sofiane; Simoncelli, Giorgia; Verdirosa, Federica; Docquier, Jean-Denis; Moreau, Yohann; Krimm, Isabelle; Crouzy, Serge; Peuchmaur, Marine | - | |
| A standard numbering scheme for class C β-lactamases | 1-gen-2020 | Mack, A. R.; Barnes, M. D.; Taracila, M. A.; Hujer, A. M.; Hujer, K. M.; Cabot, G.; Feldgarden, M.; Haft, D. H.; Klimke, W.; Van Den Akker, F.; Vila, A. J.; Smania, A.; Haider, S.; Papp-Wallace, K. M.; Bradford, P. A.; Rossolini, G. M.; Docquier, J. D.; Frere, J. -M.; Galleni, M.; Hanson, N. D.; Oliver, A.; Plesiat, P.; Poirel, L.; Nordmann, P.; Palzkill, T. G.; Jacoby, G. A.; Bush, K.; Bonomo, R. A. | - | |
| Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization | 1-gen-2018 | Pasero, Carolina; D'Agostino, Ilaria; De Luca, Filomena; Zamperini, Claudio; Deodato, Davide; Truglio, Giuseppina I.; Sannio, Filomena; DEL PRETE, Rosita; Ferraro, Teresa; Visaggio, Daniela; Mancini, Arianna; Guglielmi, Mario B.; Visca, Paolo; Docquier, Jean-Denis; Botta, Maurizio | - | |
| Amino acid replacement at position 228 induces fluctuation in the Ω-loop of KPC-3 and reduces the affinity against oxyimino cephalosporins: Kinetic and molecular dynamics studies | 1-gen-2020 | Piccirilli, A.; Brisdelli, F.; Docquier, J. D.; Aschi, M.; Cherubini, S.; De Luca, F.; Matagne, A.; Amicosante, G.; Perilli, M. | - | |
| An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library | 1-gen-2024 | Ardino, C.; Sannio, F.; Poli, G.; Galati, S.; Dreassi, E.; Botta, L.; Docquier, J. D.; D'Agostino, I. | - | |
| An update on β-lactamase inhibitor discovery and development | 1-gen-2018 | Docquier, Jean-Denis; Mangani, Stefano | - | |
| Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy | 1-gen-2021 | Martin, M. J.; Corey, B. W.; Sannio, F.; Hall, L. R.; Macdonald, U.; Jones, B. T.; Mills, E. G.; Harless, C.; Stam, J.; Maybank, R.; Kwak, Y.; Schaufler, K.; Becker, K.; Hubner, N. -O.; Cresti, S.; Tordini, G.; Valassina, M.; Cusi, M. G.; Bennett, J. W.; Russo, T. A.; Mcgann, P. T.; Lebreton, F.; Docquier, J | - | |
| ANT2681: SAR studies leading to the identification of a metallo-β-lactamase inhibitor with potential for clinical use in combination with meropenem for the treatment of infections caused by NDM-Producing enterobacteriaceae | 1-gen-2020 | Davies, D. T.; Leiris, S.; Sprynski, N.; Castandet, J.; Lozano, C.; Bousquet, J.; Zalacain, M.; Vasa, S.; Dasari, P. K.; Pattipati, R.; Vempala, N.; Gujjewar, S.; Godi, S.; Jallala, R.; Sathyap, R. R.; Darshanoju, N. A.; Ravu, V. R.; Juventhala, R. R.; Pottabathini, N.; Sharma, S.; Pothukanuri, S.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Mangani, S.; Docquier, J. D.; Lemonnier, M.; Everett, M. | - | |
| Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA | 1-gen-2022 | D'Agostino, I.; Ardino, C.; Poli, G.; Sannio, F.; Lucidi, M.; Poggialini, F.; Visaggio, D.; Rango, E.; Filippi, S.; Petricci, E.; Visca, P.; Botta, L.; Docquier, J. -D.; Dreassi, E. | - | |
| Antibiotic Resistance, Medical Need and Development of Novel Antibacterials | 1-gen-2014 | Docquier, JEAN DENIS | - |