IRIS
BRINDISI, MARGHERITA
 Distribuzione geografica
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Continente #
NA - Nord America 5.936
EU - Europa 4.570
AS - Asia 1.676
SA - Sud America 280
AF - Africa 43
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 7
Totale 12.521
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Nazione #
US - Stati Uniti d'America 5.884
GB - Regno Unito 1.249
RU - Federazione Russa 981
CN - Cina 699
IT - Italia 594
IE - Irlanda 539
SG - Singapore 503
DE - Germania 275
UA - Ucraina 269
SE - Svezia 268
BR - Brasile 233
FR - Francia 141
HK - Hong Kong 138
FI - Finlandia 107
VN - Vietnam 76
TR - Turchia 66
IN - India 45
KR - Corea 39
CA - Canada 33
NL - Olanda 28
ES - Italia 22
AR - Argentina 20
CZ - Repubblica Ceca 20
AT - Austria 17
BD - Bangladesh 17
JP - Giappone 17
CI - Costa d'Avorio 15
GR - Grecia 15
BE - Belgio 14
MX - Messico 11
IR - Iran 9
MA - Marocco 8
ZA - Sudafrica 8
EG - Egitto 7
ID - Indonesia 7
IQ - Iraq 7
PL - Polonia 7
SA - Arabia Saudita 7
AU - Australia 6
PE - Perù 6
UZ - Uzbekistan 6
EC - Ecuador 5
IL - Israele 5
PK - Pakistan 5
AE - Emirati Arabi Uniti 4
AZ - Azerbaigian 4
CL - Cile 4
CO - Colombia 4
EU - Europa 4
JO - Giordania 4
RO - Romania 4
VE - Venezuela 4
BG - Bulgaria 3
DK - Danimarca 3
KZ - Kazakistan 3
NO - Norvegia 3
PY - Paraguay 3
XK - ???statistics.table.value.countryCode.XK??? 3
BY - Bielorussia 2
CH - Svizzera 2
GE - Georgia 2
HU - Ungheria 2
JM - Giamaica 2
KG - Kirghizistan 2
LB - Libano 2
LT - Lituania 2
OM - Oman 2
TN - Tunisia 2
TV - Tuvalu 2
TW - Taiwan 2
AL - Albania 1
AO - Angola 1
BB - Barbados 1
BO - Bolivia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
HN - Honduras 1
KE - Kenya 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
NI - Nicaragua 1
NP - Nepal 1
NZ - Nuova Zelanda 1
RS - Serbia 1
TJ - Tagikistan 1
TM - Turkmenistan 1
TT - Trinidad e Tobago 1
Totale 12.521
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Città #
Southend 1.131
Fairfield 795
Dallas 633
Ashburn 605
Dublin 536
Woodbridge 368
Siena 336
Seattle 324
Houston 300
Wilmington 288
Chandler 287
Cambridge 284
Moscow 251
Singapore 242
Jacksonville 228
Santa Clara 210
Beijing 206
Ann Arbor 178
Hong Kong 137
Princeton 101
Dearborn 82
New York 74
Nanjing 73
Los Angeles 61
Izmir 59
Helsinki 51
San Diego 48
Munich 45
Boardman 43
Hefei 41
Fremont 38
San Mateo 38
Seoul 37
The Dalles 37
Shanghai 33
Buffalo 26
Milan 26
Nanchang 26
Columbus 22
Guangzhou 22
Hanoi 22
London 22
Bengaluru 21
São Paulo 21
Lappeenranta 20
Washington 20
Council Bluffs 19
Shenyang 19
Brno 18
Ho Chi Minh City 18
Jinan 18
Redwood City 17
San Francisco 17
Hebei 16
Lancaster 16
Berlin 15
Abidjan 14
Brussels 14
Düsseldorf 14
Kunming 14
Maastricht 14
Nuremberg 13
Montreal 12
Málaga 12
Norwalk 12
Tokyo 12
Vienna 12
Atlanta 11
Brooklyn 11
Florence 11
Redondo Beach 11
Stockholm 11
Avellino 10
Denver 10
Menlo Park 10
Tianjin 10
Toronto 10
Venezia 10
Aachen 9
Changsha 9
Chicago 9
Frankfurt am Main 9
Poplar 9
Portsmouth 9
Turku 9
Boston 8
Catanzaro 8
Dong Ket 8
Jiaxing 8
Ningbo 8
Phoenix 8
Rome 7
Borgo San Lorenzo 6
Orem 6
Rio de Janeiro 6
Taizhou 6
Tashkent 6
Warsaw 6
Zhengzhou 6
Dhaka 5
Totale 9.044
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Nome #
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation 403
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 378
Development of novel cyclic peptides as pro-apoptotic agents 367
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 358
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 349
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 340
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 330
Synthetic spirocyclic endoperoxides: new antimalarial scaffolds 303
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 297
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 294
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 292
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 291
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 290
Identification of novel fluorescent probes preventing PrP(Sc) replication in prion diseases 283
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 278
Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies 266
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 256
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents 249
Telomerase-based cancer therapeutics: a review on their clinical trials 246
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 246
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity 244
An efficient approach to chiral C8/C9-Piperazino-Substituted 1,4-Benzodiazepin-2-ones as peptidomimetic scaffolds 233
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 214
Design, Synthesis, Biological Evaluation, and X‐ray Studies of HIV‐1 Protease Inhibitors with Modified P2′ Ligands of Darunavir 213
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders 212
Screening and phenotypical characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) inhibitors as multistage antischistosomal agents 209
Computational tool for fast in silico evaluation of hERG K+ channel affinity 208
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation 208
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations 206
Raising the bar in anticancer therapy: recent advances in, and perspectives on, telomerase inhibitors 204
Synthetic studies toward bicyclic endoperoxides presenting polar side chains 203
Achmatowicz reaction and its application in the syntheses of bioactive molecules 201
Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants 196
null 195
Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1'-P2' ligands 195
Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex 192
Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1 '-P2 ' ligands 189
Organic Carbamates in Drug Design and Medicinal Chemistry 186
Site-directed mutagenesis of key residues unveiled a novel allosteric site on human adenosine kinase for Pyrrolobenzoxa(thia)zepinone non-nucleoside inhibitors 185
Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: definition of the structural determinants for enzyme inhibition 184
HCV-targeted Antivirals: Current Status and Future Challenges 177
Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis 174
Rational design of the first difluorostatone-based PfSUB1 inhibitors 172
Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand 168
The Curtius rearrangement: mechanistic insight and recent applications in natural product syntheses 160
Tacrine based human cholinesterase inhibitors: synthesis of peptidic-tethered derivatives and their effects on potency and selectivity 156
Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand 149
The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry 147
Highly stereoselective asymmetric aldol routes to tert-butyl-2-(3,5-difluorophenyl)-1-oxiran-2-yl)ethyl)carbamates: Building blocks for novel protease inhibitors 144
Nature Inspired Molecular Design: Stereoselective Synthesis of Bicyclic and Polycyclic Ethers for Potent HIV-1 Protease Inhibitors 135
Highly Selective and Potent Human β-Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X-ray Structure and Structure–Activity Relationship Studies 134
Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs 131
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Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents 104
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Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitors 68
Polypharmacology of dopamine receptor ligands 68
Unconventional Knoevenagel-type indoles: Synthesis and cell-based studies for the identification of pro-apoptotic agents 55
Sustainable Joullié–Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors 37
Totale 12.771
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Categoria #
all - tutte 35.329
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.329
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.278 0 0 0 0 0 298 183 209 111 300 112 65
2021/2022903 70 105 71 39 36 21 47 24 37 165 111 177
2022/20231.003 57 89 147 134 108 200 22 87 100 25 23 11
2023/2024927 32 15 85 34 43 275 294 35 6 40 16 52
2024/20251.539 51 76 217 91 177 104 20 57 184 75 153 334
2025/20262.691 287 494 496 519 858 37 0 0 0 0 0 0
Totale 12.771