BRINDISI, MARGHERITA

BRINDISI, MARGHERITA  

Dipartimento di Biotecnologie, Chimica e Farmacia  

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Risultati 1 - 20 di 88 (tempo di esecuzione: 0.0 secondi).
Titolo Data di pubblicazione Autore(i) File Abstract
A stereoselective approach to peptidomimetic BACE1 inhibitors 1-gen-2013 Butini, Stefania; Emanuele, Gabellieri; Brindisi, Margherita; Giovani, Simone; Maramai, Samuele; Kshirsagar, Giridhar; Egeria, Guarino; Brogi, Simone; Valeria La, Pietra; Mariateresa, Giustiniano; Luciana, Marinelli; Ettore, Novellino; Campiani, Giuseppe; Cappelli, Andrea; Gemma, Sandra -
A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues 1-gen-2013 Brindisi, Margherita; Gemma, Sandra; Alfano, Gloria; Kshirsagar, Giridhar; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania -
A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides 1-gen-2013 Gemma, Sandra; Kunjir, SANIL ASHOK; Brindisi, Margherita; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania -
Achmatowicz reaction and its application in the syntheses of bioactive molecules 1-gen-2016 Ghosh, Arun K.; Brindisi, Margherita -
Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation 1-gen-2017 Brogi, Simone; Maramai, Samuele; Brindisi, Margherita; Chemi, Giulia; Porcari, Valentina; Corallo, Claudio; Gennari, Luigi; Novellino, Ettore; Ramunno, Anna; Butini, Stefania; Campiani, Giuseppe; Gemma, Sandra -
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders 1-gen-2019 Brogi, Simone; Campiani, Giuseppe; Brindisi, Margherita; Butini, Stefania -
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 1-gen-2018 Vallone, Alessandra; D'Alessandro, Sarah; Brogi, Simone; Brindisi, Margherita; Chemi, Giulia; Alfano, Gloria; Lamponi, Stefania; Lee, Soon Goo; Jez, Joseph M.; Koolen, Karin J. M.; Dechering, Koen J.; Saponara, Simona; Fusi, Fabio; Gorelli, Beatrice; Taramelli, Donatella; Parapini, Silvia; Caldelari, Reto; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania -
Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas 1-gen-2020 Khan, T.; Relitti, N.; Brindisi, M.; Magnano, S.; Zisterer, D.; Gemma, S.; Butini, S.; Campiani, G. -
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 1-gen-2019 D'Alessandro, S.; Alfano, G.; Di Cerbo, L.; Brogi, S.; Chemi, G.; Relitti, N.; Brindisi, M.; Lamponi, S.; Novellino, E.; Campiani, G.; Gemma, S.; Basilico, N.; Taramelli, D.; Baratto, M. C.; Pogni, R.; Butini, S. -
Computational tool for fast in silico evaluation of hERG K+ channel affinity 1-gen-2017 Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Brogi, Simone; Butini, Stefania; Brindisi, Margherita -
The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry 1-gen-2018 Ghosh, A. K.; Brindisi, M.; Sarkar, A. -
The Curtius rearrangement: mechanistic insight and recent applications in natural product syntheses 1-gen-2018 Ghosh, Arun K.; Sarkar, Anindya; Brindisi, Margherita -
Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis 1-gen-2018 Ghosh, A. K.; Nyalapatla, R. P.; Kovela, S.; Rao, K. V.; Brindisi, M.; Osswald, H. L.; Amano, M.; Aoki, M.; Agniswamy, J.; Wang, Y. -F.; Weber, I. T.; Mitsuya, H. -
Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants 1-gen-2018 Ghosh, Arun K; Rao, Kalapala Venkateswara; Nyalapatla, Prasanth R; Kovela, Satish; Brindisi, Margherita; Osswald, Heather L; Sekhara Reddy, Bhavanam; Agniswamy, Johnson; Wang, Yuan-Fang; Aoki, Manabu; Hattori, Shin-Ichiro; Weber, Irene T; Mitsuya, Hiroaki -
Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex 1-gen-2017 Ghosh, Arun K.; Brindisi, Margherita; Nyalapatla, Prasanth R.; Takayama, Jun; Ella-Menye, Jean-Rene; Yashchuk, Sofiya; Agniswamy, Johnson; Wang, Yuan-Fang; Aoki, Manabu; Amano, Masayuki; Weber, Irene T.; Mitsuya, Hiroaki -
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents. 1-gen-2008 C., Fattorusso; Campiani, Giuseppe; G., Kukreja; M., Persico; Butini, Stefania; Romano, MARIA PIA; Altarelli, Maria; S., Ros; Brindisi, Margherita; Savini, Luisa; E., Novellino; Nacci, Vito; E., Fattorusso; S., Parapini; N., Basilico; D., Taramelli; V., Yardley; S., Croft; M., Borriello; Gemma, Sandra -
Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1 '-P2 ' ligands 1-gen-2017 Ghosh, Arun K.; Brindisi, Margherita; Yen, Yu-Chen; Cã¡rdenas, Emilio L.; Ella-Menye, Jean-Rene; Kumaragurubaran, Nagaswamy; Huang, Xiangping; Tang, Jordan; Mesecar, Andrew D. -
Design, Synthesis, Biological Evaluation, and X‐ray Studies of HIV‐1 Protease Inhibitors with Modified P2′ Ligands of Darunavir 1-gen-2017 Ghosh, Arun K.; Fyvie, W. Sean; Brindisi, Margherita; Steffey, Melinda; Agniswamy, Johnson; Wang, Yuan-Fang; Aoki, Manabu; Amano, Masayuki; Weber, Irene T.; Mitsuya, Hiroaki -
Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand 1-gen-2018 Ghosh, A. K.; Ghosh, K.; Brindisi, M.; Lendy, E. K.; Yen, Y. -C.; Kumaragurubaran, N.; Huang, X.; Tang, J.; Mesecar, A. D. -
Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1'-P2' ligands 1-gen-2017 Ghosh, Arun K.; Sean Fyvie, W.; Brindisi, Margherita; Steffey, Melinda; Agniswamy, Johnson; Wang, Yuan-Fang; Aoki, Manabu; Amano, Masayuki; Weber, Irene T.; Mitsuya, Hiroaki -