BRAI, ANNALAURA
BRAI, ANNALAURA
Dipartimento di Biotecnologie, Chimica e Farmacia
A Greener Technique for Microwave-Assisted O-Silylation and Silyl Ether Deprotection of Uridine and Other Substrates
2022-01-01 Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E.
An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines
2013-01-01 Botta, Maurizio; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, M.; Schenone, S.; Botta, M.
DDX3X Helicase Inhibitors as a New Strategy to Fight the West Nile Virus Infection
2019-01-01 Brai, Annalaura; Martelli, Francesco; Riva, Valentina; Garbelli, Anna; Fazi, Roberta; Zamperini, Claudio; Pollutri, Alessandro; Falsitta, Lucia; Ronzini, Stefania; Maccari, Laura; Maga, Giovanni; Giannecchini, Simone; Botta, Maurizio
DDX3X inhibitors, an effective way to overcome HIV-1 resistance
2020-01-01 Brai, Annalaura; Riva, Valentina; Saladini, Francesco; Zamperini, Claudio; Trivisani, CLAUDIA IMMACOLATA; Garbelli, Anna; Pennisi, Carla; Giannini, Alessia; Boccuto, Adele; Bugli, Francesca; Martini, Maurizio; Sanguinetti, Maurizio; Dreassi, Elena; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio
DEAD-Box Helicase DDX3X as a Host Target against Emerging Viruses: New Insights for Medicinal Chemical Approaches
2022-01-01 Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E.
Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family
2016-01-01 Tintori, Cristina; Brai, Annalaura; DASSO LANG, MARIA CHIARA; Deodato, Davide; Greco, Antonia Michela; Bizzarri, Bruno Mattia; Cascone, Lorena; Casian, Alexandru; Zamperini, Claudio; Dreassi, Elena; Crespan, Emmanuele; Maga, Giovanni; Vanham, Guido; Ceresola, Elisa; Canducci, Filippo; Ariën, Kevin K.; Botta, Maurizio
Exploring the implication of DDX3X in DENV infection: discovery of the first-in-class DDX3X fluorescent inhibitor
2020-01-01 Brai, Annalaura; Boccuto, Adele; Monti, Martina; Marchi, Serena; Vicenti, Ilaria; Saladini, Francesco; Trivisani, CLAUDIA IMMACOLATA; Pollutri, Alessandro; Trombetta, CLAUDIA MARIA; Montomoli, Emanuele; Riva, Valentina; Garbelli, Anna; Maria Nola, Emanuele; Zazzi, Maurizio; Maga, Giovanni; Dreassi, Elena; Botta, Maurizio
Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors
2015-01-01 Fazi, Roberta; Tintori, Cristina; Brai, Annalaura; Botta, Lorenzo; Selvaraj, Manikandan; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents
2016-01-01 Brai, Annalaura; Fazi, Roberta; Tintori, Cristina; Zamperini, Claudio; Bugli, Francesca; Sanguinetti, Maurizio; Stigliano, Egidio; Esté, José; Badia, Roger; Franco, Sandra; Martinez, Miguel A.; Martinez, Javier P.; Meyerhans, Andreas; Saladini, Francesco; Zazzi, Maurizio; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio
Inhibition of HIV-1 Reverse Transcriptase Dimerization by Small Molecules
2016-01-01 Tintori, Cristina; Corona, Angela; Esposito, Francesca; Brai, Annalaura; Grandi, Nicole; Ceresola, Elisa Rita; Clementi, Massimo; Canducci, Filippo; Tramontano, Enzo; Botta, Maurizio
Novel broad spectrum virucidal molecules against enveloped viruses
2018-01-01 Cagno, Valeria; Tintori, Cristina; Civra, Andrea; Cavalli, Roberta; Tiberi, Marika; Botta, Lorenzo; Brai, Annalaura; Poli, Giulio; Tapparel, Caroline; Lembo, David; Botta, Maurizio
Protein-protein interactions and human cellular cofactors as new targets for HIV therapy
2014-01-01 Tintori, Cristina; Brai, Annalaura; Fallacara, ANNA LUCIA; Fazi, Roberta; Schenone, Silvia; Botta, Maurizio
Proteins from Tenebrio molitor: An interesting functional ingredient and a source of ACE inhibitory peptides
2022-01-01 Brai, A.; Immacolata Trivisani, C.; Vagaggini, C.; Stella, R.; Angeletti, R.; Iovenitti, G.; Francardi, V.; Dreassi, E.
Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection
2021-01-01 Ciccosanti, Fabiola; Di Rienzo, Martina; Romagnoli, Alessandra; Colavita, Francesca; Refolo, Giulia; Castilletti, Concetta; Agrati, Chiara; Brai, Annalaura; Manetti, Fabrizio; Botta, Lorenzo; Capobianchi, Maria Rosaria; Ippolito, Giuseppe; Piacentini, Mauro; Fimia, Gian Maria
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives
2022-01-01 Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides
2018-01-01 Tintori, Cristina; Iovenitti, Giulia; Ceresola, Elisa Rita; Ferrarese, Roberto; Zamperini, Claudio; Brai, Annalaura; Poli, Giulio; Dreassi, Elena; Cagno, Valeria; Lembo, David; Canducci, Filippo; Botta, Maurizio
Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma
2021-01-01 Rango, E.; D'Antona, L.; Iovenitti, G.; Brai, A.; Mancini, A.; Zamperini, C.; Trivisani, C. I.; Marianelli, S.; Fallacara, A. L.; Molinari, A.; Cianciusi, A.; Schenone, S.; Perrotti, N.; Dreassi, E.; Botta, M.
Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X
2019-01-01 Brai, Annalaura; Ronzini, Stefania; Riva, Valentina; Botta, Lorenzo; Zamperini, Claudio; Borgini, Matteo; Trivisani, Claudia Immacolata; Garbelli, Anna; Pennisi, Carla; Boccuto, Adele; Saladini, Francesco; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio
Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses
2020-01-01 Riva, V.; Garbelli, A.; Brai, A.; Casiraghi, F.; Fazi, R.; Trivisani, C. I.; Boccuto, A.; Saladini, F.; Vicenti, I.; Martelli, F.; Zazzi, M.; Giannecchini, S.; Dreassi, E.; Botta, M.; Maga, G.
Viral Envelope Membrane: A Special Entry Pathway and a Promising Drug Target
2021-01-01 Palombi, Nastasja; Brai, Annalaura; Gerace, Martina; DI MARIA, Salvatore; Orofino, Francesco; Corelli, Federico
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A Greener Technique for Microwave-Assisted O-Silylation and Silyl Ether Deprotection of Uridine and Other Substrates | 1-gen-2022 | Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E. | - | |
| An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines | 1-gen-2013 | Botta, Maurizio; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, M.; Schenone, S.; Botta, M. | - | |
| DDX3X Helicase Inhibitors as a New Strategy to Fight the West Nile Virus Infection | 1-gen-2019 | Brai, Annalaura; Martelli, Francesco; Riva, Valentina; Garbelli, Anna; Fazi, Roberta; Zamperini, Claudio; Pollutri, Alessandro; Falsitta, Lucia; Ronzini, Stefania; Maccari, Laura; Maga, Giovanni; Giannecchini, Simone; Botta, Maurizio | - | |
| DDX3X inhibitors, an effective way to overcome HIV-1 resistance | 1-gen-2020 | Brai, Annalaura; Riva, Valentina; Saladini, Francesco; Zamperini, Claudio; Trivisani, CLAUDIA IMMACOLATA; Garbelli, Anna; Pennisi, Carla; Giannini, Alessia; Boccuto, Adele; Bugli, Francesca; Martini, Maurizio; Sanguinetti, Maurizio; Dreassi, Elena; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio | - | |
| DEAD-Box Helicase DDX3X as a Host Target against Emerging Viruses: New Insights for Medicinal Chemical Approaches | 1-gen-2022 | Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E. | - | |
| Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family | 1-gen-2016 | Tintori, Cristina; Brai, Annalaura; DASSO LANG, MARIA CHIARA; Deodato, Davide; Greco, Antonia Michela; Bizzarri, Bruno Mattia; Cascone, Lorena; Casian, Alexandru; Zamperini, Claudio; Dreassi, Elena; Crespan, Emmanuele; Maga, Giovanni; Vanham, Guido; Ceresola, Elisa; Canducci, Filippo; Ariën, Kevin K.; Botta, Maurizio | - | |
| Exploring the implication of DDX3X in DENV infection: discovery of the first-in-class DDX3X fluorescent inhibitor | 1-gen-2020 | Brai, Annalaura; Boccuto, Adele; Monti, Martina; Marchi, Serena; Vicenti, Ilaria; Saladini, Francesco; Trivisani, CLAUDIA IMMACOLATA; Pollutri, Alessandro; Trombetta, CLAUDIA MARIA; Montomoli, Emanuele; Riva, Valentina; Garbelli, Anna; Maria Nola, Emanuele; Zazzi, Maurizio; Maga, Giovanni; Dreassi, Elena; Botta, Maurizio | - | |
| Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors | 1-gen-2015 | Fazi, Roberta; Tintori, Cristina; Brai, Annalaura; Botta, Lorenzo; Selvaraj, Manikandan; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio | - | |
| Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents | 1-gen-2016 | Brai, Annalaura; Fazi, Roberta; Tintori, Cristina; Zamperini, Claudio; Bugli, Francesca; Sanguinetti, Maurizio; Stigliano, Egidio; Esté, José; Badia, Roger; Franco, Sandra; Martinez, Miguel A.; Martinez, Javier P.; Meyerhans, Andreas; Saladini, Francesco; Zazzi, Maurizio; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio | - | |
| Inhibition of HIV-1 Reverse Transcriptase Dimerization by Small Molecules | 1-gen-2016 | Tintori, Cristina; Corona, Angela; Esposito, Francesca; Brai, Annalaura; Grandi, Nicole; Ceresola, Elisa Rita; Clementi, Massimo; Canducci, Filippo; Tramontano, Enzo; Botta, Maurizio | - | |
| Novel broad spectrum virucidal molecules against enveloped viruses | 1-gen-2018 | Cagno, Valeria; Tintori, Cristina; Civra, Andrea; Cavalli, Roberta; Tiberi, Marika; Botta, Lorenzo; Brai, Annalaura; Poli, Giulio; Tapparel, Caroline; Lembo, David; Botta, Maurizio | - | |
| Protein-protein interactions and human cellular cofactors as new targets for HIV therapy | 1-gen-2014 | Tintori, Cristina; Brai, Annalaura; Fallacara, ANNA LUCIA; Fazi, Roberta; Schenone, Silvia; Botta, Maurizio | - | |
| Proteins from Tenebrio molitor: An interesting functional ingredient and a source of ACE inhibitory peptides | 1-gen-2022 | Brai, A.; Immacolata Trivisani, C.; Vagaggini, C.; Stella, R.; Angeletti, R.; Iovenitti, G.; Francardi, V.; Dreassi, E. | - | |
| Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection | 1-gen-2021 | Ciccosanti, Fabiola; Di Rienzo, Martina; Romagnoli, Alessandra; Colavita, Francesca; Refolo, Giulia; Castilletti, Concetta; Agrati, Chiara; Brai, Annalaura; Manetti, Fabrizio; Botta, Lorenzo; Capobianchi, Maria Rosaria; Ippolito, Giuseppe; Piacentini, Mauro; Fimia, Gian Maria | - | |
| Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives | 1-gen-2022 | Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano | - | |
| Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides | 1-gen-2018 | Tintori, Cristina; Iovenitti, Giulia; Ceresola, Elisa Rita; Ferrarese, Roberto; Zamperini, Claudio; Brai, Annalaura; Poli, Giulio; Dreassi, Elena; Cagno, Valeria; Lembo, David; Canducci, Filippo; Botta, Maurizio | - | |
| Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma | 1-gen-2021 | Rango, E.; D'Antona, L.; Iovenitti, G.; Brai, A.; Mancini, A.; Zamperini, C.; Trivisani, C. I.; Marianelli, S.; Fallacara, A. L.; Molinari, A.; Cianciusi, A.; Schenone, S.; Perrotti, N.; Dreassi, E.; Botta, M. | - | |
| Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X | 1-gen-2019 | Brai, Annalaura; Ronzini, Stefania; Riva, Valentina; Botta, Lorenzo; Zamperini, Claudio; Borgini, Matteo; Trivisani, Claudia Immacolata; Garbelli, Anna; Pennisi, Carla; Boccuto, Adele; Saladini, Francesco; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio | - | |
| Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses | 1-gen-2020 | Riva, V.; Garbelli, A.; Brai, A.; Casiraghi, F.; Fazi, R.; Trivisani, C. I.; Boccuto, A.; Saladini, F.; Vicenti, I.; Martelli, F.; Zazzi, M.; Giannecchini, S.; Dreassi, E.; Botta, M.; Maga, G. | - | |
| Viral Envelope Membrane: A Special Entry Pathway and a Promising Drug Target | 1-gen-2021 | Palombi, Nastasja; Brai, Annalaura; Gerace, Martina; DI MARIA, Salvatore; Orofino, Francesco; Corelli, Federico | - |