BRAI, ANNALAURA
BRAI, ANNALAURA
Dipartimento di Biotecnologie, Chimica e Farmacia
A greener technique for microwave-assisted O-Silylation and silyl ether deprotection of uridine and other substrates
2022-01-01 Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E.
A novel bioresponsive self-immolative spacer based on aza-quinone methide reactivity for the controlled release of thiols, phenols, amines, sulfonamides or amides
2024-01-01 Ermini, Elena; Brai, Annalaura; Cini, Elena; Finetti, Federica; Giannini, Giuseppe; Padula, Daniele; Paradisi, Lucrezia; Poggialini, Federica; Trabalzini, Lorenza; Tolu, Paola; Taddei, Maurizio
An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines
2013-01-01 Botta, Maurizio; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, M.; Schenone, S.; Botta, M.
An Innovation 10 Years in the Making: The Stories in the Pages of ACS Medicinal Chemistry Letters
2022-01-01 Altman, Ryan A.; Brai, Annalaura; Golden, Jennifer; La Regina, Giuseppe; Li, Zhengqiu; Moore, Terry W.; Pomerantz, William C. K.; Rajapaksa, Naomi S.; Adams, Ashley M.
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme
2023-01-01 Poggialini, Federica; Vagaggini, Chiara; Brai, Annalaura; Pasqualini, Claudia; Crespan, Emmanuele; Maga, Giovanni; Perini, Cecilia; Cabella, Noemi; Botta, Lorenzo; Musumeci, Francesca; Frosini, Maria; Schenone, Silvia; Dreassi, Elena
DDX3 inhibitors show antiviral activity against positive-sense single-stranded RNA viruses but not against negative-sense single-stranded RNA viruses: The coxsackie B model
2020-01-01 Quaranta, Paola; Lottini, Giulia; Chesi, Giulia; Contrafatto, Flavia; Russotto, Roberta; Macera, Lisa; Lai, Michele; Spezia, Pietro Giorgio; Brai, Annalaura; Botta, Maurizio; Freer, Giulia; Pistello, Mauro
DDX3X Helicase Inhibitors as a New Strategy to Fight the West Nile Virus Infection
2019-01-01 Brai, Annalaura; Martelli, Francesco; Riva, Valentina; Garbelli, Anna; Fazi, Roberta; Zamperini, Claudio; Pollutri, Alessandro; Falsitta, Lucia; Ronzini, Stefania; Maccari, Laura; Maga, Giovanni; Giannecchini, Simone; Botta, Maurizio
DDX3X inhibitors, an effective way to overcome HIV-1 resistance
2020-01-01 Brai, Annalaura; Riva, Valentina; Saladini, Francesco; Zamperini, Claudio; Trivisani, Claudia; Garbelli, Anna; Pennisi, Carla; Giannini, Alessia; Boccuto, Adele; Bugli, Francesca; Martini, Maurizio; Sanguinetti, Maurizio; Dreassi, Elena; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio
DEAD-Box Helicase DDX3X as a host target against emerging viruses: new insights for medicinal chemical approaches
2022-01-01 Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E.
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors
2024-01-01 Di Stefano, M.; Masoni, S.; Bononi, G.; Poli, G.; Galati, S.; Gado, F.; Manzi, S.; Vagaggini, C.; Brai, A.; Caligiuri, I.; Asif, K.; Rizzolio, F.; Macchia, M.; Chicca, A.; Sodi, A.; Di Bussolo, V.; Minutolo, F.; Meier, P.; Gertsch, J.; Granchi, C.; Dreassi, E.; Tuccinardi, T.
Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family
2016-01-01 Tintori, Cristina; Brai, Annalaura; DASSO LANG, MARIA CHIARA; Deodato, Davide; Greco, Antonia Michela; Bizzarri, Bruno Mattia; Cascone, Lorena; Casian, Alexandru; Zamperini, Claudio; Dreassi, Elena; Crespan, Emmanuele; Maga, Giovanni; Vanham, Guido; Ceresola, Elisa; Canducci, Filippo; Ariën, Kevin K.; Botta, Maurizio
Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma
2023-01-01 Vagaggini, Chiara; Brai, Annalaura; Bonente, Denise; Lombardi, Jessica; Poggialini, Federica; Pasqualini, Claudia; Barone, Virginia; Nicoletti, Claudio; Bertelli, Eugenio; Dreassi, Elena
Efficient use of agricultural waste to naturally fortify Tenebrio molitor mealworms and evaluation of their nutraceutical properties
2023-01-01 Brai, A.; Poggialini, F.; Trivisani, C. I.; Vagaggini, C.; Tarchi, F.; Francardi, V.; Dreassi, E.
Exploitation of the Nutraceutical Potential of the Infesting Seaweed Chaetomorpha linum as a Yellow Mealworms’ Feed: Focus on Nutrients and Antioxidant Activity
2025-01-01 Brai, A.; Brogi, E.; Tarchi, F.; Poggialini, F.; Vagaggini, C.; Simoni, S.; Francardi, V.; Dreassi, E
Exploiting fall foliage by-products to optimize Tenebrio molitor nutraceutical value
2023-01-01 Brai, A.; Provenzani, M. P.; Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Tarchi, F.; Frosinini, R.; Francardi, V.; Simoni, S.; Dreassi, E.
Exploring the implication of DDX3X in DENV infection: discovery of the first-in-class DDX3X fluorescent inhibitor
2020-01-01 Brai, A.; Boccuto, A.; Monti, M.; Marchi, S.; Vicenti, I.; Saladini, F.; Trivisani, C. I.; Pollutri, A.; Trombetta, C. M.; Montomoli, E.; Riva, V.; Garbelli, A.; Nola, E. M.; Zazzi, M.; Maga, G.; Dreassi, E.; Botta, M.
Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors
2015-01-01 Fazi, Roberta; Tintori, Cristina; Brai, Annalaura; Botta, Lorenzo; Selvaraj, Manikandan; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents
2016-01-01 Brai, Annalaura; Fazi, Roberta; Tintori, Cristina; Zamperini, Claudio; Bugli, Francesca; Sanguinetti, Maurizio; Stigliano, Egidio; Esté, José; Badia, Roger; Franco, Sandra; Martinez, Miguel A.; Martinez, Javier P.; Meyerhans, Andreas; Saladini, Francesco; Zazzi, Maurizio; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio
Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity
2024-01-01 Fiorucci, D.; Meaccini, M.; Poli, G.; Stincarelli, M. A.; Vagaggini, C.; Giannecchini, S.; Sutto-Ortiz, P.; Canard, B.; Decroly, E.; Dreassi, E.; Brai, A.; Botta, M.
In This Issue, Volume 12, Issue 7
2021-01-01 Brai, Annalaura
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A greener technique for microwave-assisted O-Silylation and silyl ether deprotection of uridine and other substrates | 1-gen-2022 | Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E. | - | |
| A novel bioresponsive self-immolative spacer based on aza-quinone methide reactivity for the controlled release of thiols, phenols, amines, sulfonamides or amides | 1-gen-2024 | Ermini, Elena; Brai, Annalaura; Cini, Elena; Finetti, Federica; Giannini, Giuseppe; Padula, Daniele; Paradisi, Lucrezia; Poggialini, Federica; Trabalzini, Lorenza; Tolu, Paola; Taddei, Maurizio | - | |
| An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines | 1-gen-2013 | Botta, Maurizio; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, M.; Schenone, S.; Botta, M. | - | |
| An Innovation 10 Years in the Making: The Stories in the Pages of ACS Medicinal Chemistry Letters | 1-gen-2022 | Altman, Ryan A.; Brai, Annalaura; Golden, Jennifer; La Regina, Giuseppe; Li, Zhengqiu; Moore, Terry W.; Pomerantz, William C. K.; Rajapaksa, Naomi S.; Adams, Ashley M. | - | |
| Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme | 1-gen-2023 | Poggialini, Federica; Vagaggini, Chiara; Brai, Annalaura; Pasqualini, Claudia; Crespan, Emmanuele; Maga, Giovanni; Perini, Cecilia; Cabella, Noemi; Botta, Lorenzo; Musumeci, Francesca; Frosini, Maria; Schenone, Silvia; Dreassi, Elena | - | |
| DDX3 inhibitors show antiviral activity against positive-sense single-stranded RNA viruses but not against negative-sense single-stranded RNA viruses: The coxsackie B model | 1-gen-2020 | Quaranta, Paola; Lottini, Giulia; Chesi, Giulia; Contrafatto, Flavia; Russotto, Roberta; Macera, Lisa; Lai, Michele; Spezia, Pietro Giorgio; Brai, Annalaura; Botta, Maurizio; Freer, Giulia; Pistello, Mauro | - | |
| DDX3X Helicase Inhibitors as a New Strategy to Fight the West Nile Virus Infection | 1-gen-2019 | Brai, Annalaura; Martelli, Francesco; Riva, Valentina; Garbelli, Anna; Fazi, Roberta; Zamperini, Claudio; Pollutri, Alessandro; Falsitta, Lucia; Ronzini, Stefania; Maccari, Laura; Maga, Giovanni; Giannecchini, Simone; Botta, Maurizio | - | |
| DDX3X inhibitors, an effective way to overcome HIV-1 resistance | 1-gen-2020 | Brai, Annalaura; Riva, Valentina; Saladini, Francesco; Zamperini, Claudio; Trivisani, Claudia; Garbelli, Anna; Pennisi, Carla; Giannini, Alessia; Boccuto, Adele; Bugli, Francesca; Martini, Maurizio; Sanguinetti, Maurizio; Dreassi, Elena; Zazzi, Maurizio; Maga, Giovanni; Botta, Maurizio | - | |
| DEAD-Box Helicase DDX3X as a host target against emerging viruses: new insights for medicinal chemical approaches | 1-gen-2022 | Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E. | - | |
| Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2024 | Di Stefano, M.; Masoni, S.; Bononi, G.; Poli, G.; Galati, S.; Gado, F.; Manzi, S.; Vagaggini, C.; Brai, A.; Caligiuri, I.; Asif, K.; Rizzolio, F.; Macchia, M.; Chicca, A.; Sodi, A.; Di Bussolo, V.; Minutolo, F.; Meier, P.; Gertsch, J.; Granchi, C.; Dreassi, E.; Tuccinardi, T. | - | |
| Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family | 1-gen-2016 | Tintori, Cristina; Brai, Annalaura; DASSO LANG, MARIA CHIARA; Deodato, Davide; Greco, Antonia Michela; Bizzarri, Bruno Mattia; Cascone, Lorena; Casian, Alexandru; Zamperini, Claudio; Dreassi, Elena; Crespan, Emmanuele; Maga, Giovanni; Vanham, Guido; Ceresola, Elisa; Canducci, Filippo; Ariën, Kevin K.; Botta, Maurizio | - | |
| Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma | 1-gen-2023 | Vagaggini, Chiara; Brai, Annalaura; Bonente, Denise; Lombardi, Jessica; Poggialini, Federica; Pasqualini, Claudia; Barone, Virginia; Nicoletti, Claudio; Bertelli, Eugenio; Dreassi, Elena | - | |
| Efficient use of agricultural waste to naturally fortify Tenebrio molitor mealworms and evaluation of their nutraceutical properties | 1-gen-2023 | Brai, A.; Poggialini, F.; Trivisani, C. I.; Vagaggini, C.; Tarchi, F.; Francardi, V.; Dreassi, E. | - | |
| Exploitation of the Nutraceutical Potential of the Infesting Seaweed Chaetomorpha linum as a Yellow Mealworms’ Feed: Focus on Nutrients and Antioxidant Activity | 1-gen-2025 | Brai, A.; Brogi, E.; Tarchi, F.; Poggialini, F.; Vagaggini, C.; Simoni, S.; Francardi, V.; Dreassi, E | - | |
| Exploiting fall foliage by-products to optimize Tenebrio molitor nutraceutical value | 1-gen-2023 | Brai, A.; Provenzani, M. P.; Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Tarchi, F.; Frosinini, R.; Francardi, V.; Simoni, S.; Dreassi, E. | - | |
| Exploring the implication of DDX3X in DENV infection: discovery of the first-in-class DDX3X fluorescent inhibitor | 1-gen-2020 | Brai, A.; Boccuto, A.; Monti, M.; Marchi, S.; Vicenti, I.; Saladini, F.; Trivisani, C. I.; Pollutri, A.; Trombetta, C. M.; Montomoli, E.; Riva, V.; Garbelli, A.; Nola, E. M.; Zazzi, M.; Maga, G.; Dreassi, E.; Botta, M. | - | |
| Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors | 1-gen-2015 | Fazi, Roberta; Tintori, Cristina; Brai, Annalaura; Botta, Lorenzo; Selvaraj, Manikandan; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio | - | |
| Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents | 1-gen-2016 | Brai, Annalaura; Fazi, Roberta; Tintori, Cristina; Zamperini, Claudio; Bugli, Francesca; Sanguinetti, Maurizio; Stigliano, Egidio; Esté, José; Badia, Roger; Franco, Sandra; Martinez, Miguel A.; Martinez, Javier P.; Meyerhans, Andreas; Saladini, Francesco; Zazzi, Maurizio; Garbelli, Anna; Maga, Giovanni; Botta, Maurizio | - | |
| Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity | 1-gen-2024 | Fiorucci, D.; Meaccini, M.; Poli, G.; Stincarelli, M. A.; Vagaggini, C.; Giannecchini, S.; Sutto-Ortiz, P.; Canard, B.; Decroly, E.; Dreassi, E.; Brai, A.; Botta, M. | - | |
| In This Issue, Volume 12, Issue 7 | 1-gen-2021 | Brai, Annalaura | - |