A rapid protocol for the multicomponent microwave-assisted organocatalytic domino Knoevenagel/hetero Diels–Alder reaction (DKHDA) has been developed for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. The reported procedure could be used for the fast generation of novel substituted 2,3-dihydropyran[2,3-c]pyrazoles with potential anti-tuberculosis activity.

Radi, M., Bernardo, V., Bechi, B., Castagnolo, D., Pagano, M., & Botta, M. (2009). Microwave-assisted organocatalytic multicomponent Knoevenagel/Hetero Diels Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. TETRAHEDRON LETTERS, 50, 6572-6575 [10.1016/j.tetlet.2009.09.047].

Microwave-assisted organocatalytic multicomponent Knoevenagel/Hetero Diels Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles

RADI, MARCO;BERNARDO, VINCENZO;BECHI, BEATRICE;CASTAGNOLO, DANIELE;PAGANO, MAFALDA;BOTTA, MAURIZIO
2009

Abstract

A rapid protocol for the multicomponent microwave-assisted organocatalytic domino Knoevenagel/hetero Diels–Alder reaction (DKHDA) has been developed for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. The reported procedure could be used for the fast generation of novel substituted 2,3-dihydropyran[2,3-c]pyrazoles with potential anti-tuberculosis activity.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/9219
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