A new method is reported for the synthesis of the α,β-unsaturated nitrone moiety characteristic of the stephacidin/avrainvillamide family of bioactive prenylated indole alkaloids. Application to the synthesis of stephacidin analogs and a potential biological probe are showcased.

A new method is reported for the synthesis of the α,β-unsaturated nitrone moiety characteristic of the stephacidin/avrainvillamide family of bioactive prenylated indole alkaloids. Application to the synthesis of stephacidin analogs and a potential biological probe are showcased. © 2009 Elsevier Ltd. All rights reserved.

Hafensteiner, B.D., Escribano, M., Petricci, E., & Baran, P.S. (2009). An improved synthesis of α,β-unsaturated nitrones relevant to the stephacidins and analogs thereof. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 19(14), 3808-3810 [10.1016/j.bmcl.2009.04.045].

An improved synthesis of α,β-unsaturated nitrones relevant to the stephacidins and analogs thereof

PETRICCI, ELENA;
2009

Abstract

A new method is reported for the synthesis of the α,β-unsaturated nitrone moiety characteristic of the stephacidin/avrainvillamide family of bioactive prenylated indole alkaloids. Application to the synthesis of stephacidin analogs and a potential biological probe are showcased.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/417340
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