New 4-anilinoquinoline-3-carboxylic acids, N-[3-carboxyquinolyl (4)]anthranilic acids and their corresponding esters were synthetized by reacting 4-chloro-3-carbethoxyquinolines with substituted anilines and methyl anthranilate respectively. All the compounds were tested for antiinflammatory and analgesic activities. Some derivatives showed a significant antiinflammatory activity comparable to that of indomethacin.

Pellerano, C., Savini, L., Massarelli, P., Bruni, G., & Fiaschi, A.I. (1990). New quinoline derivatives: synthesis and evaluation for antiinflammatory and analgesic properties - Note I. IL FARMACO, 45(3), 269-284.

New quinoline derivatives: synthesis and evaluation for antiinflammatory and analgesic properties - Note I

PELLERANO, CESARE;SAVINI, LUISA;MASSARELLI, PAOLA;BRUNI, GIANCARLO;FIASCHI, ANNA IDA
1990

Abstract

New 4-anilinoquinoline-3-carboxylic acids, N-[3-carboxyquinolyl (4)]anthranilic acids and their corresponding esters were synthetized by reacting 4-chloro-3-carbethoxyquinolines with substituted anilines and methyl anthranilate respectively. All the compounds were tested for antiinflammatory and analgesic activities. Some derivatives showed a significant antiinflammatory activity comparable to that of indomethacin.
Pellerano, C., Savini, L., Massarelli, P., Bruni, G., & Fiaschi, A.I. (1990). New quinoline derivatives: synthesis and evaluation for antiinflammatory and analgesic properties - Note I. IL FARMACO, 45(3), 269-284.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/402198
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