Purine nucleotides were studied in human peripheral blood lymphocytes from normal subjects and patients with chronic B-cell lymphocytic leukemia (B-CLL). Nucleotide content was determined by high performance liquid chromatography (HPLC). The overall rate of purine nucleotide synthesis was measured following the incorporation of 14C-formate into the nucleotides of a lymphocytic suspension. Results indicate a substantially reduced rate of purine nucleotide metabolism.
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|Titolo:||Purine nucleotide metabolism in lymphocytes of B-cell chronic lymphocytic leukemia patients.|
|Citazione:||Tabucchi, A., Carlucci, F., Leoncini, R., Vannoni, D., Consolmagno, E., Marinello, E., et al. (1995). Purine nucleotide metabolism in lymphocytes of B-cell chronic lymphocytic leukemia patients. BIOMÉDECINE & PHARMACOTHÉRAPIE, 49(3), 141-144.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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