A procedure to immobilise saccharides on a gold substrate based on self-assembled monolayer (SAM) methodology associated to click chemistry is presented. Alkanethiol self-assembled on gold was obtained. The SAM was modified in order to introduce an alkyne-terminated arm which could react with azido modified saccharides through click chemistry. The substrates were characterised at each modification step by reflection absorption infrared spectroscopy and time of flight secondary ion mass spectrometry. The stability of the organic arm immobilised on the gold substrate was also verified.
Leone, G., Consumi, M., Tognazzi, A., Magnani, A. (2010). Realisation and chemical characterisation of a model system for saccharide-based biosensor. THIN SOLID FILMS, 519(1), 462-470 [10.1016/j.tsf.2010.07.099].
Realisation and chemical characterisation of a model system for saccharide-based biosensor.
LEONE, GEMMA;M. CONSUMI;MAGNANI, AGNESE
2010-01-01
Abstract
A procedure to immobilise saccharides on a gold substrate based on self-assembled monolayer (SAM) methodology associated to click chemistry is presented. Alkanethiol self-assembled on gold was obtained. The SAM was modified in order to introduce an alkyne-terminated arm which could react with azido modified saccharides through click chemistry. The substrates were characterised at each modification step by reflection absorption infrared spectroscopy and time of flight secondary ion mass spectrometry. The stability of the organic arm immobilised on the gold substrate was also verified.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Thin Solid Films_2010.pdf
non disponibili
Tipologia:
Post-print
Licenza:
NON PUBBLICO - Accesso privato/ristretto
Dimensione
1.27 MB
Formato
Adobe PDF
|
1.27 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/34068