Immobilized lipase from Mucor miehei (RML) catalyzed the regioselective acylation of the C-2 side-chain of the C-alkyl resorcin[4]arene tetra-alcohol 1 in the 1,2-alternate form in organic solvents using vinyl acetate as acylating reagent. The influence of reaction parameters and solvent choice were also studied. Docking simulations allowed the determination of the binding geometry of 1, revealing the importance of Trp88 residue in stabilizing the Michaelis–Menten complex between enzyme and substrate.

Botta, B., Zappia, G., Tafi, A., Botta, M., Manetti, F., Cernia, E., et al. (2003). Erratum: Lipase-catalyzed regioselective acylation of resorcin[4]arenes (Journal of Molecular Catalysis B: Enzymatic (2002) 16 (24-247) PII: S1381117701000686). JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 21(4-6), 313 [10.1016/S1381-1177(02)00221-7].

Erratum: Lipase-catalyzed regioselective acylation of resorcin[4]arenes (Journal of Molecular Catalysis B: Enzymatic (2002) 16 (24-247) PII: S1381117701000686)

TAFI, ANDREA;BOTTA, MAURIZIO;MANETTI, FABRIZIO;
2003-01-01

Abstract

Immobilized lipase from Mucor miehei (RML) catalyzed the regioselective acylation of the C-2 side-chain of the C-alkyl resorcin[4]arene tetra-alcohol 1 in the 1,2-alternate form in organic solvents using vinyl acetate as acylating reagent. The influence of reaction parameters and solvent choice were also studied. Docking simulations allowed the determination of the binding geometry of 1, revealing the importance of Trp88 residue in stabilizing the Michaelis–Menten complex between enzyme and substrate.
2003
Botta, B., Zappia, G., Tafi, A., Botta, M., Manetti, F., Cernia, E., et al. (2003). Erratum: Lipase-catalyzed regioselective acylation of resorcin[4]arenes (Journal of Molecular Catalysis B: Enzymatic (2002) 16 (24-247) PII: S1381117701000686). JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 21(4-6), 313 [10.1016/S1381-1177(02)00221-7].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/30341
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