Taxanes and epothilones: New insights into the binding mode of epothilone B with tubulin support a previous hypothesis based on a pseudoreceptor model, in which taxanes and epothilones binding in the β-tubulin binding pocket share several pharmacophoric elements.
Forli, S., Manetti, F., Altmann, K.H., Botta, M. (2010). Evaluation of Novel Epothilone Analogues by means of a common Pharmacophore and a QSAR Pseudoreceptor model for Taxanes and Epothilones. CHEMMEDCHEM, 5, 35-40 [10.1002/cmdc.200900303].
Evaluation of Novel Epothilone Analogues by means of a common Pharmacophore and a QSAR Pseudoreceptor model for Taxanes and Epothilones
MANETTI, FABRIZIO;BOTTA, MAURIZIO
2010-01-01
Abstract
Taxanes and epothilones: New insights into the binding mode of epothilone B with tubulin support a previous hypothesis based on a pseudoreceptor model, in which taxanes and epothilones binding in the β-tubulin binding pocket share several pharmacophoric elements.
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