Brain glycoprotein sugars were studied during human brain development. Marked changes were found in the sugar content of glycopeptides derived from soluble and insoluble glycoproteins, showing a general decrease in the soluble and an increase in the insoluble fraction. The data indicate that changes in glycan moiety and/or in glycoprotein population occur during development. The existence of a‘critical period’in glycoprotein development which coincides with the formation of axonal and synaptic membranes sprouting has been established (Dobbing, 1971). Copyright © 1978, Wiley Blackwell. All rights reserved.
Federico, A., Di Benedetta, C., Milici, N. (1978). Glycoprotein changes during the development of human brain. JOURNAL OF NEUROCHEMISTRY, 31(4), 797-800 [10.1111/j.1471-4159.1978.tb00113.x].
Glycoprotein changes during the development of human brain
Federico, A.;
1978-01-01
Abstract
Brain glycoprotein sugars were studied during human brain development. Marked changes were found in the sugar content of glycopeptides derived from soluble and insoluble glycoproteins, showing a general decrease in the soluble and an increase in the insoluble fraction. The data indicate that changes in glycan moiety and/or in glycoprotein population occur during development. The existence of a‘critical period’in glycoprotein development which coincides with the formation of axonal and synaptic membranes sprouting has been established (Dobbing, 1971). Copyright © 1978, Wiley Blackwell. All rights reserved.
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https://hdl.handle.net/11365/28387
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