Premature atherosclerosis and cardiac complications have been reported among the systemic manifestations of cerebrotendinous xanthomatosis (CTX), a rare bile acid disorder with predominantly neurological features. In some cases, myocardial infarction has been the cause of sudden death. We examined nine CTX patients to determine whether they also had clinical or subclinical signs of cardiovascular disorders. In four of them, transthoracic echocardiography showed thickening of the interatrial septum compatible with lipomatous hypertrophy. The unexpected association of the two abnormalities is unlikely to be coincidental and suggests that careful cardiac examination should be considered, even in the absence of clinical manifestations.
Scheda prodotto non validato
Scheda prodotto in fase di analisi da parte dello staff di validazione
|Titolo:||Cerebrotendinous xanthomatosis: evidence of lipomatous hypertrophy of the atrial septum.|
|Rivista:||JOURNAL OF NEUROLOGY|
|Citazione:||Dotti, M., Mondillo, S., Plewnia, K., Agricola, E., & Federico, A. (1998). Cerebrotendinous xanthomatosis: evidence of lipomatous hypertrophy of the atrial septum. JOURNAL OF NEUROLOGY, 245(11), 723-726.|
|Appare nelle tipologie:||1.1 Articolo in rivista|