Endometriosis is an important contributing factor to chronic pelvic pain and infertility. Matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) have each been implicated in the establishment of endometriotic lesions. Since relaxin regulates the expression of MMPs and VEGF in the endometrium, we tested the hypothesis that relaxin plays a role in endometriosis by comparing the expression of relaxin mRNA and its LGR7 (RXFP1) receptor mRNA in normal human endometrium to those in samples from patients with endometriosis

Morelli, S.S., Petraglia, F., Weiss, G., Luisi, S., Florio, P., Goldsmith, L.T. (2009). Relaxin in endometriosis. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1160, 138-139 [10.1111/j.1749-6632.2008.03792.x].

Relaxin in endometriosis

PETRAGLIA, F.;LUISI, S.;FLORIO, P.;
2009-01-01

Abstract

Endometriosis is an important contributing factor to chronic pelvic pain and infertility. Matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) have each been implicated in the establishment of endometriotic lesions. Since relaxin regulates the expression of MMPs and VEGF in the endometrium, we tested the hypothesis that relaxin plays a role in endometriosis by comparing the expression of relaxin mRNA and its LGR7 (RXFP1) receptor mRNA in normal human endometrium to those in samples from patients with endometriosis
2009
Morelli, S.S., Petraglia, F., Weiss, G., Luisi, S., Florio, P., Goldsmith, L.T. (2009). Relaxin in endometriosis. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1160, 138-139 [10.1111/j.1749-6632.2008.03792.x].
File in questo prodotto:
File Dimensione Formato  
j.1749-6632.2008.03792.x.pdf

non disponibili

Tipologia: Post-print
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 59.85 kB
Formato Adobe PDF
59.85 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/23462
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo