The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.

Nevena, V., Sanja, G., Jelena, P., Vladimir, P., Botta, M., & Veljković, V.J. (2008). Discovery of new therapeutic targets by the informational spectrum method. CURRENT PROTEIN & PEPTIDE SCIENCE, 9, 493-506.

Discovery of new therapeutic targets by the informational spectrum method

Botta, Maurizio;
2008

Abstract

The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/20937
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