The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.
Nevena, V., Sanja, G., Jelena, P., Vladimir, P., Botta, M., Veljković, V.J. (2008). Discovery of new therapeutic targets by the informational spectrum method. CURRENT PROTEIN & PEPTIDE SCIENCE, 9(5), 493-506 [10.2174/138920308785915245].
Discovery of new therapeutic targets by the informational spectrum method
Botta, Maurizio;
2008-01-01
Abstract
The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/20937
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