Introduction: The study aim is to compare Video-Assisted (VATS) and Robotic-Assisted (RATS) lobectomy in the effort to identify advantages and limits of robotic procedures considering the high costs and specific surgeon training. Materials and methods: This is a monocentric prospective randomized trial in which patients suitable for miniinvasive lobectomy were randomized 1:2 in two groups: Group A, RATS (25 patients), and Group B, VATS (50 patients). The two groups were compared in terms of perioperative and postoperative results with a mean follow up of 37.9 (+/- 10.9) months. Results: We observed a significant reduction of pleural effusion on day 1 (140 ml vs 214, p = 0.003) and day 2 (186 vs 321, p = 0.001) for group A. The Visual Analogue Scale (VAS) showed significantly lower pain in the 1st p.o. day in group A (0,92 vs 1,17, p = 0,005). Surgery time in Group B was significantly lower (160 min vs 180, p = 0.036), but had a higher onset of atrial fibrillation and other cardiac arrhythmias (0/25 vs 9/50, p = 0.038). The OS and DFS were similar between the two groups (95.5 % vs 93.1 %, and 95.5 % vs 89.7 %, respectively). Furthermore, no statistical difference in the evaluation of quality of life during follow-up was found. Conclusions: The RATS approach, although burdened by higher surgical costs, constitutes a valid alternative to VATS; as it determines a lower inflammatory insult, with a consequent reduction in pleural effusion, less postoperative pain and cardiological comorbidities for the patient, it can potentially determine the shortening in hospitalization. In addition, RATS allows accurate lymph node dissection, which permit to reach results that are not inferior to VATS in terms of long-term outcomes.

Catelli, C., Corzani, R., Zanfrini, E., Franchi, F., Ghisalberti, M., Ligabue, T., et al. (2023). RoboticAssisted (RATS) versus Video-Assisted (VATS) lobectomy: a monocentric prospective randomized trial. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 49(12) [10.1016/j.ejso.2023.107256].

RoboticAssisted (RATS) versus Video-Assisted (VATS) lobectomy: a monocentric prospective randomized trial

Catelli C.;Corzani R.;Franchi F.;Ghisalberti M.;Meniconi F.;Addamo E.;Paladini P.;Luzzi L.
2023-01-01

Abstract

Introduction: The study aim is to compare Video-Assisted (VATS) and Robotic-Assisted (RATS) lobectomy in the effort to identify advantages and limits of robotic procedures considering the high costs and specific surgeon training. Materials and methods: This is a monocentric prospective randomized trial in which patients suitable for miniinvasive lobectomy were randomized 1:2 in two groups: Group A, RATS (25 patients), and Group B, VATS (50 patients). The two groups were compared in terms of perioperative and postoperative results with a mean follow up of 37.9 (+/- 10.9) months. Results: We observed a significant reduction of pleural effusion on day 1 (140 ml vs 214, p = 0.003) and day 2 (186 vs 321, p = 0.001) for group A. The Visual Analogue Scale (VAS) showed significantly lower pain in the 1st p.o. day in group A (0,92 vs 1,17, p = 0,005). Surgery time in Group B was significantly lower (160 min vs 180, p = 0.036), but had a higher onset of atrial fibrillation and other cardiac arrhythmias (0/25 vs 9/50, p = 0.038). The OS and DFS were similar between the two groups (95.5 % vs 93.1 %, and 95.5 % vs 89.7 %, respectively). Furthermore, no statistical difference in the evaluation of quality of life during follow-up was found. Conclusions: The RATS approach, although burdened by higher surgical costs, constitutes a valid alternative to VATS; as it determines a lower inflammatory insult, with a consequent reduction in pleural effusion, less postoperative pain and cardiological comorbidities for the patient, it can potentially determine the shortening in hospitalization. In addition, RATS allows accurate lymph node dissection, which permit to reach results that are not inferior to VATS in terms of long-term outcomes.
2023
Catelli, C., Corzani, R., Zanfrini, E., Franchi, F., Ghisalberti, M., Ligabue, T., et al. (2023). RoboticAssisted (RATS) versus Video-Assisted (VATS) lobectomy: a monocentric prospective randomized trial. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 49(12) [10.1016/j.ejso.2023.107256].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/1261575