Incidence of sudden death in Rett syndrome is greater than that of the general population and cardiac electrical instability is a prime suspect cause. Our study shows that girls with Rett syndrome had significantly lower heart rate variability (marker of autonomic disarray) and longer corrected QT intervals compared with an age-matched group of healthy girls. These abnormalities increased with advancing stages of the syndrome. These findings suggest a possible role of cardiac dysfunction in the sudden death associated with Rett syndrome.

Guideri, F., Acampa, M., Hayek, G., Zappella, M., Di Perri, T. (1999). Reduced heart rate variability in patients affected with Rett syndrome. A possible explanation for sudden death. NEUROPEDIATRICS, 30(3), 146-148 [10.1055/s-2007-973480].

Reduced heart rate variability in patients affected with Rett syndrome. A possible explanation for sudden death

Guideri F.;Acampa M.;Di Perri T.
1999-01-01

Abstract

Incidence of sudden death in Rett syndrome is greater than that of the general population and cardiac electrical instability is a prime suspect cause. Our study shows that girls with Rett syndrome had significantly lower heart rate variability (marker of autonomic disarray) and longer corrected QT intervals compared with an age-matched group of healthy girls. These abnormalities increased with advancing stages of the syndrome. These findings suggest a possible role of cardiac dysfunction in the sudden death associated with Rett syndrome.
1999
Guideri, F., Acampa, M., Hayek, G., Zappella, M., Di Perri, T. (1999). Reduced heart rate variability in patients affected with Rett syndrome. A possible explanation for sudden death. NEUROPEDIATRICS, 30(3), 146-148 [10.1055/s-2007-973480].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/1183965
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