We report a procedure for the continuous-flow production of cyclohexanone from phenol on the basis of the use of sodium formate as a biomass-derived source of hydrogen and Pd/C as an easily accessible catalyst system. The reaction worked in water at pH12.0 at 90Â°C. By setting a packed reactor charged with the Pd/C catalyst (10wt%) at a flow rate of 0.5mLmin-1, we achieved continuous-flow production of cyclohexanone in high yield with high selectivity and productivity.
|Titolo:||Continuous-Flow Palladium-Catalyzed Synthesis of Cyclohexanones from Phenols using Sodium Formate as a Safe Hydrogen Source|
|Citazione:||Valentini, F., Santillo, N., Petrucci, C., Lanari, D., Petricci, E., Taddei, M., et al. (2018). Continuous-Flow Palladium-Catalyzed Synthesis of Cyclohexanones from Phenols using Sodium Formate as a Safe Hydrogen Source. CHEMCATCHEM.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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